R. Jeggo

发表

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

Caleb Webber, Guy B. Williams, Mara Cercignani, 2019, Brain : a journal of neurology.

PFE-360-induced LRRK2 inhibition induces reversible, non-adverse renal changes in rats.

P. Jensen, R. Jeggo, Steen Larsen, 2018, Toxicology.

Inflammatory biomarkers in Alzheimer's disease plasma

Magda Tsolaki, Edward T. Bullmore, Gareth J. Barker, 2019, Alzheimer's & Dementia.

University of Birmingham Hippocampal 5HT7 receptors signal phosphorylation of the GluA1 subunit to facilitate AMPA receptor mediatedneurotransmission in vitro and in vivo

D. Hoyer, N. Barnes, L. Carboni, 2016 .

Effects of D-amino acid oxidase inhibition on memory performance and long-term potentiation in vivo

T. Large, U. Campbell, M. Varney, 2013, Pharmacology research & perspectives.

The role of central 5‐HT3 receptors in vagal reflex inputs to neurones in the nucleus tractus solitarius of anaesthetized rats

A. Ramage, R. Jeggo, D. Jordan, 2005, The Journal of physiology.

P62 accumulates through neuroanatomical circuits in response to tauopathy propagation

M. Millan, K. Duff, C. Goulbourne, 2021, Acta Neuropathologica Communications.

MRZ-99030 – A novel modulator of Aβ aggregation: II – Reversal of Aβ oligomer-induced deficits in long-term potentiation (LTP) and cognitive performance in rats and mice

Veronica Egger, C. Parsons, C. Chambon, 2015, Neuropharmacology.

MRZ-99030 e A novel modulator of Ab aggregation: II e Reversal of Ab oligomer-induced deficits in long-term potentiation (LTP) and cognitive performance in rats and mice

Veronica Egger, C. Parsons, C. Chambon, 2022 .

Long-Term Exposure to PFE-360 in the AAV-α-Synuclein Rat Model: Findings and Implications

P. Jensen, R. Jeggo, L. Badolo, 2018, eNeuro.

Parkinson's disease-like burst firing activity in subthalamic nucleus induced by AAV-α-synuclein is normalized by LRRK2 modulation

P. Jensen, R. Jeggo, L. Badolo, 2018, Neurobiology of Disease.

α7-nAChR agonist enhances neural plasticity in the hippocampus via a GABAergic circuit.

L. Leventhal, D. Flood, H. Patzke, 2016, Journal of neurophysiology.

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

M. Mattson, S. Oliet, G. Casadesus, 2020, Nature Reviews Drug Discovery.

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

M. Mattson, S. Oliet, G. Casadesus, 2020, Nature Reviews Drug Discovery.

Electrophysiological Techniques for Studying Synaptic Activity In Vivo

F. Zhao, R. Jeggo, D. Spanswick, 2000, Current protocols in pharmacology.

The N-methylated peptide SEN304 powerfully inhibits Aβ(1-42) toxicity by perturbing oligomer formation.

A. Doig, C. Eyers, D. Scopes, 2012, Biochemistry.

Effect of pulmonary C‐fibre afferent stimulation on cardiac vagal neurones in the nucleus ambiguus in anaesthetized cats

J. Jones, A. Ramage, R. Jeggo, 2000, The Journal of physiology.

Hippocampal 5‐HT7 receptors signal phosphorylation of the GluA1 subunit to facilitate AMPA receptor mediated‐neurotransmission in vitro and in vivo

D. Hoyer, N. Barnes, L. Carboni, 2016, British journal of pharmacology.

Aβ oligomer toxicity inhibitor protects memory in models of synaptic toxicity

E. O’Hare, D. Scopes, J. Mark Treherne, 2012, British journal of pharmacology.

Translational PK–PD modelling of molecular target modulation for the AMPA receptor positive allosteric modulator Org 26576

R. Bursi, M. Hutmacher, J. Schipper, 2011, Psychopharmacology.

A seeding-based neuronal model of tau aggregation for use in drug discovery

Inês S. Amorim, L. Cistarelli, E. Cecon, 2023, PloS one.

A Modest Increase in 11C-PK11195-Positron Emission Tomography TSPO Binding in Depression Is Not Associated With Serum C-Reactive Protein or Body Mass Index

Karen H. Adams, E. Bullmore, F. Turkheimer, 2021, Biological psychiatry. Cognitive neuroscience and neuroimaging.

Lack of support for bexarotene as a treatment for Alzheimer's disease

P. Mcgeer, E. Mcgeer, P. Hobson, 2016, Neuropharmacology.

Orally bioavailable small molecule drug protects memory in Alzheimer's disease models

E. O’Hare, D. Scopes, Eun-mee Kim, 2013, Neurobiology of Aging.

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

Tobias C. Wood, Karen H. Adams, C. Webber, 2019, Brain : a journal of neurology.

Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease

Karen H. Adams, E. Bullmore, F. Turkheimer, 2023, Journal of Neuroinflammation.

Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77‐LH‐28‐1

M. Whittington, C. Langmead, C. Davies, 2008, British journal of pharmacology.

The N-methylated peptide SEN304 powerfully inhibits Aβ(1-42) toxicity by perturbing oligomer formation.

A. Doig, C. Eyers, D. Scopes, 2012, Biochemistry.

Novel 5-aryloxypyrimidine SEN1576 as a candidate for the treatment of Alzheimer's disease.

E. O’Hare, D. Scopes, Eun-mee Kim, 2014, The international journal of neuropsychopharmacology.

Hippocampal 5-HT 7 receptors signal phosphorylation of the GluA 1 subunit to facilitate AMPA receptor mediated-neurotransmission in vitro and in vivo

D. Hoyer, N. Barnes, L. Carboni, 2016 .

In Vivo Electrophysiological Recording Techniques for the Study of Neuropathic Pain in Rodent Models

F. Zhao, R. Jeggo, D. Spanswick, 2014, Current protocols in pharmacology.