Anna C. Schinzel

发表

KRAS and YAP1 Converge to Regulate EMT and Tumor Survival

Joseph Rosenbluh, Arjun Bhutkar, William C. Hahn, 2014, Cell.

β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

Jill P. Mesirov, Joseph Rosenbluh, Aviad Tsherniak, 2012, Cell.

CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity

Sridhar Ramaswamy, Eric S. Lander, Ian F. Dunn, 2010, PloS one.

Synthetic Lethal Interaction between Oncogenic KRAS Dependency and STK33 Suppression in Human Cancer Cells

Sridhar Ramaswamy, D. Gary Gilliland, Pablo Tamayo, 2009, Cell.

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

R. Young, W. Hahn, K. Anderson, 2011, Cell.

β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

J. Mesirov, W. Hahn, W. Goessling, 2013, Cell.

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 lysine 27 trimethylation

Jacob D. Jaffe, Charles Y. Lin, W. Hahn, 2014, Nature Genetics.

Functional genomic screening reveals asparagine dependence as a metabolic vulnerability in sarcoma

W. Hahn, A. Schinzel, R. Bronson, 2015, eLife.

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

Ben S. Wittner, B. Wittner, J. Mesirov, 2009, Nature.

Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers.

J. Mesirov, P. Tamayo, W. Hahn, 2013, Cancer discovery.

Plasticity in the Absence of NOTCH Uncovers a RUNX2-Dependent Pathway in Small Cell Lung Cancer

Kristen L. Jones, Kristen L Jones, M. Tolstorukov, 2021, Cancer Research.

Initial genome sequencing and analysis of multiple myeloma

Trevor J Pugh, A. Sivachenko, K. Cibulskis, 2011, Nature.

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia.

S. Korsmeyer, M. Moskowitz, A. Schinzel, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Castration Resistance in Prostate Cancer Is Mediated by the Kinase NEK6.

Jacob D. Jaffe, W. Hahn, P. Kantoff, 2017, Cancer research.

Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit.

Travis J Cohoon, N. Hacohen, J. Mesirov, 2014, Cancer discovery.

KRAS and YAP 1 Converge to Regulate EMT and Tumor Survival Citation

W. Hahn, T. Jacks, D. Root, 2014 .

PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA

John G Doench, W. Hahn, D. Root, 2017, Nature Communications.

Integrative genomic approaches to understanding cancer.

W. Hahn, J. Boehm, A. Schinzel, 2009, Biochimica et biophysica acta.

Oncogenic transformation and experimental models of human cancer.

William C Hahn, W. Hahn, A. Schinzel, 2008, Frontiers in bioscience : a journal and virtual library.

AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer.

Yiling Lu, Gordon B Mills, Bhaskar Dutta, 2009, Cancer cell.

Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit.

N. Hacohen, J. Mesirov, P. Tamayo, 2014, Cancer discovery.

Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target.

W. Hahn, M. Meyerson, R. Verhaak, 2013, Genes & development.

target as a functional transcriptional LMO 3 lung adenocarcinoma identifies in NKX 2-1 Integrated cistromic and expression analysis of amplified Material Supplemental

W. Hahn, M. Meyerson, R. Verhaak, 2013 .

Proapoptotic BAX and BAK Modulate the Unfolded Protein Response by a Direct Interaction with IRE1α

S. Korsmeyer, A. Schinzel, C. Hetz, 2006, Science.

Bcl-2 family members: intracellular targeting, membrane-insertion, and changes in subcellular localization

C. Borner, A. Schinzel, T. Kaufmann, 2004 .

Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis

W. Hahn, M. Loda, P. Kantoff, 2012, Proceedings of the National Academy of Sciences.

Conformational control of Bax localization and apoptotic activity by Pro168

C. Borner, A. Schinzel, M. Schuler, 2004, The Journal of cell biology.

Bcl-2 family members: integrators of survival and death signals in physiology and pathology [corrected].

C. Borner, A. Schinzel, T. Kaufmann, 2004, Biochimica et biophysica acta.

The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation

C. Borner, A. Schinzel, S. Esnault, 2009, Nature Immunology.

Genetic Screening for Myeloma Cell Susceptibility to NK Cell Mediated Lysis Using Large Lentiviral shRNA Libraries

W. Hahn, J. Ritz, J. Daley, 2008 .

PRKACA Mediates Resistance to HER2-Targeted Therapy in Breast Cancer Cells and Restores Anti-Apoptotic Signaling

W. Hahn, J. Boehm, A. Schinzel, 2014, Oncogene.

An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells.

Birgit Schoeberl, Andrew L. Kung, David M. Livingston, 2010, Cancer cell.

The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia.

W. Hahn, K. Ross, J. Aster, 2012, The Journal of clinical investigation.

An Activated ErbB 3 / NRG 1 Autocrine Loop Supports In Vivo Proliferation in Ovarian Cancer Cells

W. Hahn, M. Meyerson, H. Greulich, 2022 .

Bcl-w(edding) with mitochondria.

C. Borner, A. Schinzel, T. Kaufmann, 2004, Trends in cell biology.

Proteomic and genetic approaches identify Syk as an AML target.

Tina N. Davis, Steven A Carr, William C Hahn, 2009, Cancer cell.

The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis

Zachary T Herbert, M. Tolstorukov, S. Signoretti, 2019, Genes & development.

Tyrosine kinase pathways modulate tumor susceptibility to natural killer cells.

Stefan Heinrichs, Roberto Bellucci, William C Hahn, 2012, The Journal of clinical investigation.