T. Ueyama

发表

Myocardin Expression Is Regulated by Nkx2.5, and Its Function Is Required for Cardiomyogenesis

Q. Nie, S. Izumo, H. Kasahara, 2003, Molecular and Cellular Biology.

Csm, a Cardiac-specific Isoform of the RNA Helicase Mov10l1, Is Regulated by Nkx2.5 in Embryonic Heart*

S. Izumo, H. Kasahara, N. Yamasaki, 2003, Journal of Biological Chemistry.

Nkx2.5 homeoprotein regulates expression of gap junction protein connexin 43 and sarcomere organization in postnatal cardiomyocytes.

W. Manning, P. Kang, C. Berul, 2003, Journal of molecular and cellular cardiology.

Characterization of Homo- and Heterodimerization of Cardiac Csx/Nkx2.5 Homeoprotein*

A. Usheva, N. Horikoshi, S. Izumo, 2001, The Journal of Biological Chemistry.

Ecscr regulates insulin sensitivity and predisposition to obesity by modulating endothelial cell functions

Y. Oike, H. Yamada, S. Matoba, 2013, Nature Communications.

Manipulation of Cardiac Phosphatidylinositol 3-Kinase (PI3K)/Akt Signaling by Apoptosis Regulator through Modulating IAP Expression (ARIA) Regulates Cardiomyocyte Death during Doxorubicin-induced Cardiomyopathy*

H. Yamada, S. Matoba, K. Ikeda, 2013, The Journal of Biological Chemistry.

Skeletal muscle-derived progenitors capable of differentiating into cardiomyocytes proliferate through myostatin-independent TGF-beta family signaling.

H. Matsubara, S. Asada, E. Ashihara, 2008, Biochemical and biophysical research communications.

Periaortic adipose tissue-specific activation of the renin-angiotensin system contributes to atherosclerosis development in uninephrectomized apoE-/- mice.

Y. Mori, H. Matsubara, H. Yamada, 2013, American journal of physiology. Heart and circulatory physiology.

PARM-1 promotes cardiomyogenic differentiation through regulating the BMP/Smad signaling pathway.

H. Matsubara, Tomosaburou Takahashi, T. Ueyama, 2012, Biochemical and biophysical research communications.

Controlled delivery of basic fibroblast growth factor promotes human cardiosphere-derived cell engraftment to enhance cardiac repair for chronic myocardial infarction.

H. Matsubara, Y. Tabata, M. Komeda, 2008, Journal of the American College of Cardiology.

p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia.

H. Matsubara, M. Okigaki, S. Matoba, 2012, Journal of molecular and cellular cardiology.

NFAT5 regulates the canonical Wnt pathway and is required for cardiomyogenic differentiation.

H. Matsubara, Tomosaburou Takahashi, T. Ueyama, 2012, Biochemical and biophysical research communications.

Kobe University Repository : Kernel Tit le Heparin and heparan sulfate inhibit extracellular signal-regulated kinase act ivat ion and myocardial cell hypertrophy induced

Y. Hayashi, H. Itoh, S. Kawashima, 2017 .

Glycogen Synthase Kinase-3β is Involved in the Process of Myocardial Hypertrophy Stimulated by Insulin-Like Growth Factor-1

S. Satomi-Kobayashi, R. Toh, S. Kawashima, 2004 .

Macrophages play a unique role in the plaque calcification by enhancing the osteogenic signals exerted by vascular smooth muscle cells.

H. Matsubara, M. Okigaki, H. Yamada, 2012, Biochemical and biophysical research communications.

Transplantation of periaortic adipose tissue from angiotensin receptor blocker-treated mice markedly ameliorates atherosclerosis development in apoE–/– mice

S. Matoba, H. Yamada, K. Ikeda, 2015, Journal of the renin-angiotensin-aldosterone system : JRAAS.

Role of endothelial lipase in plasma HDL levels in a murine model of hypertriglyceridemia.

K. Hirata, T. Quertermous, T. Ishida, 2009, Journal of atherosclerosis and thrombosis.

Bone marrow angiotensin AT2 receptor deficiency aggravates atherosclerosis development by eliminating macrophage liver X receptor-mediated anti-atherogenic actions

H. Yamada, S. Matoba, T. Ueyama, 2015, Journal of the renin-angiotensin-aldosterone system : JRAAS.

Resistance to endotoxin shock in transgenic mice overexpressing endothelial nitric oxide synthase.

K. Hirata, T. Yamashita, S. Kawashima, 2000, Circulation.

Deficiency of Nectin-2 Leads to Cardiac Fibrosis and Dysfunction Under Chronic Pressure Overload

H. Matsubara, K. Hirata, J. Miyoshi, 2009, Hypertension.

PARM-1 Is an Endoplasmic Reticulum Molecule Involved in Endoplasmic Reticulum Stress-Induced Apoptosis in Rat Cardiac Myocytes

H. Matsubara, S. Asada, Tomosaburou Takahashi, 2010, PloS one.

Maternal High-Fat Diet Exaggerates Atherosclerosis in Adult Offspring by Augmenting Periaortic Adipose Tissue-Specific Proinflammatory Response

S. Matoba, H. Yamada, T. Ueyama, 2015, Arteriosclerosis, thrombosis, and vascular biology.

The coiled-coil domain of MURC/cavin-4 is involved in membrane trafficking of caveolin-3 in cardiomyocytes.

S. Matoba, Takeru Kasahara, T. Ueyama, 2015, American journal of physiology. Heart and circulatory physiology.

MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by α1-adrenergic receptors

Y. Hayashi, H. Yamada, S. Matoba, 2014, Proceedings of the National Academy of Sciences.

Serotonin-Induced Hypercontraction Through 5-Hydroxytryptamine 1B Receptors in Atherosclerotic Rabbit Coronary Arteries

K. Hirata, M. Shiomi, S. Kawashima, 2001, Circulation.

Loss of Bcl-2 During the Senescence Exacerbates the Impaired Angiogenic Functions in Endothelial Cells by Deteriorating the Mitochondrial Redox State

H. Matsubara, M. Okigaki, H. Yamada, 2011, Hypertension.

Local Overexpression of Toll-Like Receptors at the Vessel Wall Induces Atherosclerotic Lesion Formation: Synergism of TLR2 and TLR4

K. Hirata, T. Yamashita, N. Emoto, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Short-Term Treatment with an Angiotensin II Receptor Blocker Prevents Necrotic Core Formation by Inhibiting Oxidative Stress-Mediated Apoptosis in Macrophages

H. Yamada, S. Matoba, Y. Tsubakimoto, 2015 .

Xenogenic smooth muscle cell immunization reduces neointimal formation in balloon-injured rabbit carotid arteries.

K. Hirata, T. Yamashita, R. Toh, 2005, Cardiovascular research.

Endothelin-1 activates p38 mitogen-activated protein kinase via endothelin-A receptor in rat myocardial cells

S. Kawashima, M. Namiki, M. Yokoyama, 1999, Molecular and Cellular Biochemistry.

Regulation of tyrosine phosphorylation of PYK2 in vascular endothelial cells by lysophosphatidylcholine.

K. Hirata, S. Ishido, S. Kawashima, 2001, American journal of physiology. Heart and circulatory physiology.

Inhibition of p53 preserves Parkin-mediated mitophagy and pancreatic β-cell function in diabetes

S. Matoba, E. Iwai-Kanai, K. Ikeda, 2014, Proceedings of the National Academy of Sciences.

Cardiac myocytes are recruited by bone marrow-derived cells in intact murine heart.

S. Satomi-Kobayashi, K. Hattori, R. Toh, 2002, The Kobe journal of medical sciences.

Stage-Specific Role of Endogenous Smad2 Activation in Cardiomyogenesis of Embryonic Stem Cells

H. Matsubara, H. Ueno, T. Yoshikawa, 2007, Circulation research.

Stage-Specific Role of Endogenous Smad 2 Activation in Cardiomyogenesis of Embryonic

H. Matsubara, T. Yoshikawa, S. Asada, 2007 .

Decreased expression of arginase II in the kidneys of Dahl salt-sensitive rats.

T. Gotoh, M. Mori, M. Yokoyama, 2002, Hypertension research : official journal of the Japanese Society of Hypertension.

Requirement of activation of the extracellular signal-regulated kinase cascade in myocardial cell hypertrophy.

H. Hotta, S. Ishido, T. Yamashita, 1999, Journal of molecular and cellular cardiology.

MURC Variants in Cardiomyopathy

G. Dorn, H. Matsubara, A. Marian, 2011 .

Haploinsufficiency of the cardiac transcription factor Nkx2‐5 variably affects the expression of putative target genes

S. Izumo, A. Dorfman, P. Jay, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Aging differentially alters the expression of angiogenic genes in a tissue-dependent manner.

S. Matoba, H. Yamada, K. Ikeda, 2014, Biochemical and biophysical research communications.

Mitsugumin 56 (hedgehog acyltransferase‐like) is a sarcoplasmic reticulum‐resident protein essential for postnatal muscle maturation

S. Kakizawa, M. Nishi, H. Takeshima, 2015, FEBS letters.

Regulation of Tight Junction Permeability and Occludin Phosphorylation by RhoA-p160ROCK-dependent and -independent Mechanisms*

S. Tsukita, S. Kawashima, T. Hirase, 2001, The Journal of Biological Chemistry.

Physiology of the Aging Vasculature Vascular endothelial senescence : from mechanisms to pathophysiology

T. Ueyama, Masahiro Koide, Y. Nakagawa, 2008 .

Long-Term Overexpression of Hsp70 Does Not Protect against Cardiac Dysfunction and Adverse Remodeling in a MURC Transgenic Mouse Model with Chronic Heart Failure and Atrial Fibrillation

M. Febbraio, H. Kiriazis, J. McMullen, 2015, PloS one.

The small-molecule BGP-15 protects against heart failure and atrial fibrillation in mice

P. Meikle, M. Febbraio, J. Sadoshima, 2014, Nature Communications.

MURC, a Muscle-Restricted Coiled-Coil Protein That Modulates the Rho/ROCK Pathway, Induces Cardiac Dysfunction and Conduction Disturbance

H. Matsubara, K. Harada, T. Shioi, 2008, Molecular and Cellular Biology.

MicroRNA-1 facilitates skeletal myogenic differentiation without affecting osteoblastic and adipogenic differentiation.

H. Matsubara, S. Asada, K. Isodono, 2006, Biochemical and biophysical research communications.

Molecular Genetic and Functional Characterization Implicate Muscle-Restricted Coiled-Coil Gene (MURC) as a Causal Gene for Familial Dilated Cardiomyopathy

G. Dorn, H. Matsubara, A. Marian, 2011, Circulation. Cardiovascular genetics.

Apoptosis regulator through modulating IAP expression (ARIA) controls the PI3K/Akt pathway in endothelial and endothelial progenitor cells

H. Matsubara, M. Okigaki, H. Yamada, 2011, Proceedings of the National Academy of Sciences.

Downregulation of Dicer expression by serum withdrawal sensitizes human endothelial cells to apoptosis.

H. Matsubara, S. Asada, K. Isodono, 2008, American journal of physiology. Heart and circulatory physiology.

Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart

S. Matoba, E. Iwai-Kanai, K. Ikeda, 2013, Nature Communications.

Abstract 15384: MURC Promotes Recruitment of Erk1/2 to Caveolae of the Plasma Membrane and Concentric Cardiac Hypertrophy Induced by a1-adrenergic Stimulation

T. Ueyama, N. Nakanishi, T. Ogata, 2013 .

Curcumin Attenuates Doxorubicin-Induced Cardiotoxicity by Inducing Autophagy via the Regulation of JNK Phosphorylation

S. Matoba, E. Iwai-Kanai, K. Ikeda, 2014 .

Osteopontin is a myosphere-derived secretory molecule that promotes angiogenic progenitor cell proliferation through the phosphoinositide 3-kinase/Akt pathway.

H. Matsubara, S. Asada, T. Nomura, 2007, Biochemical and biophysical research communications.

Skeletal myosphere-derived progenitor cell transplantation promotes neovascularization in delta-sarcoglycan knockdown cardiomyopathy.

H. Matsubara, S. Asada, E. Ashihara, 2007, Biochemical and biophysical research communications.

MURC deficiency in smooth muscle attenuates pulmonary hypertension

S. Matoba, Takeru Kasahara, T. Ueyama, 2016, Nature Communications.

Loss of MURC/Cavin-4 induces JNK and MMP-9 activity enhancement in vascular smooth muscle cells and exacerbates abdominal aortic aneurysm.

H. Yamada, S. Matoba, H. Aoki, 2017, Biochemical and biophysical research communications.

Activated RhoA stimulates c-fos gene expression in myocardial cells.

K. Hirata, S. Kawashima, M. Yokoyama, 1997, Circulation research.

Cerivastatin suppresses lipopolysaccharide-induced ICAM-1 expression through inhibition of Rho GTPase in BAEC.

K. Hirata, S. Kawashima, N. Inoue, 2000, Biochemical and biophysical research communications.

Human cardiac stem cells exhibit mesenchymal features and are maintained through Akt/GSK-3beta signaling.

H. Matsubara, H. Yaku, E. Ashihara, 2007, Biochemical and biophysical research communications.

Heparin and heparan sulfate inhibit extracellular signal-regulated kinase activation and myocardial cell hypertrophy induced by endothelin-1.

H. Itoh, S. Kawashima, M. Yokoyama, 2001, The Kobe journal of medical sciences.

Transplantation of cardiotrophin-1-expressing myoblasts to the left ventricular wall alleviates the transition from compensatory hypertrophy to congestive heart failure in Dahl salt-sensitive hypertensive rats.

S. Satomi-Kobayashi, R. Toh, S. Kawashima, 2004, Journal of the American College of Cardiology.

Clonally amplified cardiac stem cells are regulated by Sca-1 signaling for efficient cardiovascular regeneration

H. Matsubara, T. Nakagami, E. Ashihara, 2007, Journal of Cell Science.

Early Inflammatory Reactions in Atherosclerosis Are Induced by Proline-Rich Tyrosine Kinase/Reactive Oxygen Species–Mediated Release of Tumor Necrosis Factor-&agr; and Subsequent Activation of the p21Cip1/Ets-1/p300 System

Koji Ikeda, Hiroyuki Yamada, H. Matsubara, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Loss of Apoptosis Regulator through Modulating IAP Expression (ARIA) Protects Blood Vessels from Atherosclerosis*

K. Hatakeyama, Y. Asada, H. Yamada, 2014, The Journal of Biological Chemistry.

H. Yamada, S. Matoba, Ju Chen, 2015, PloS one.

Therapeutic potential of stem/progenitor cells in human skeletal muscle for cardiovascular regeneration.

T. Kubo, H. Matsubara, H. Yaku, 2007, Current stem cell research & therapy.

Shear stress enhances glutathione peroxidase expression in endothelial cells.

S. Kawashima, N. Inoue, M. Yokoyama, 2000, Biochemical and biophysical research communications.

Pyk2 aggravates hypoxia-induced pulmonary hypertension by activating HIF-1α.

S. Matoba, K. Ikeda, Makoto Ariyoshi, 2015, American journal of physiology. Heart and circulatory physiology.

Serglycin is a novel adipocytokine highly expressed in epicardial adipose tissue.

H. Matsubara, Y. Naito, K. Mizushima, 2013, Biochemical and biophysical research communications.

Kobe University Repository : Kernel タイトル Tit le Heparin and heparan sulfate inhibit extracellular signal-regulated kinase act ivat ion and myocardial cell hypertrophy induced by endothelin-1 著者

Y. Hayashi, H. Itoh, S. Kawashima, 2018 .

PTRF/Cavin-1 Deficiency Causes Cardiac Dysfunction Accompanied by Cardiomyocyte Hypertrophy and Cardiac Fibrosis

S. Matoba, Takeru Kasahara, T. Ueyama, 2016, PloS one.

Lysophosphatidylcholine inhibits endothelial cell migration and proliferation via inhibition of the extracellular signal-regulated kinase pathway.

K. Hirata, H. Hotta, S. Ishido, 2000, Arteriosclerosis, thrombosis, and vascular biology.

MURC, a muscle-restricted coiled-coil protein, is involved in the regulation of skeletal myogenesis.

H. Matsubara, S. Asada, K. Isodono, 2008, American journal of physiology. Cell physiology.