Mary C. Nakamura

发表

Brain trauma elicits non-canonical macrophage activation states

Charles C. Kim, Christine L. Hsieh, Mary C. Nakamura, 2016, Journal of Neuroinflammation.

Natural Killer Cells and Their Role in Disease

Mary C. Nakamura, 2002 .

Osteoclasts—the innate immune cells of the bone

Yalei Wu, Mary C. Nakamura, Yalei Wu, 2008, Autoimmunity.

Binding and uptake of H-ferritin are mediated by human transferrin receptor-1

W. Seaman, F. Torti, S. Torti, 2010, Proceedings of the National Academy of Sciences.

Lower PDL1/2 and AXL Expression on Lung Myeloid Cells Suggests Inflammatory Bias in Smoking and COPD.

Mary C. Nakamura, S. Zeng, M. Arjomandi, 2020, American journal of respiratory cell and molecular biology.

CIITA: A Master Regulator of Adaptive Immunity Shows Its Innate Side in the Bone

Mary C. Nakamura, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis

Lara A. Kahale, L. Fraenkel, E. Akl, 2021, Arthritis & rheumatology.

2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis

Lara A. Kahale, L. Fraenkel, E. Akl, 2021, Arthritis & rheumatology.

Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group

M. Suarez‐Almazor, M. Lacouture, I. Puzanov, 2017, Journal of Immunotherapy for Cancer.

TREM2, a DAP12‐Associated Receptor, Regulates Osteoclast Differentiation and Function

L. Lanier, W. Seaman, M. B. Humphrey, 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The Loss of Cbl-Phosphatidylinositol 3-Kinase Interaction Perturbs RANKL-mediated Signaling, Inhibiting Bone Resorption and Promoting Osteoclast Survival*

M. Barbe, A. Sanjay, W. Langdon, 2010, The Journal of Biological Chemistry.

β-catenin Signaling Regulates Cell Fate Decisions at the Transition Zone of the Chondro-Osseous Junction During Fracture Healing

E. Hsiao, D. Hu, T. Miclau, 2020, bioRxiv.

Glucocorticoid excess in mice results in early activation of osteoclastogenesis and adipogenesis and prolonged suppression of osteogenesis: a longitudinal study of gene expression in bone tissue from glucocorticoid-treated mice.

N. Lane, W. Yao, Mary C. Nakamura, 2008, Arthritis and rheumatism.

α1 / α2 domains of H‐2Dd, but not H‐2Ld, induce “missing self” reactivity in vivo – No effect of H‐2Ld on protection against NK cells expressing the inhibitory receptor Ly49G2

J. Ryan, Mary C. Nakamura, M. Johansson, 1998 .

Specificity of the Murine NK Cell Inhibitory Restricts the Allelic d Domain of H-2D 2 a The

W. Seaman, J. Ryan, Mary C. Nakamura, 1998 .

Mouse Ly-49D Recognizes H-2Dd and Activates Natural Killer Cell Cytotoxicity

W. Seaman, J. Ortaldo, J. Ryan, 1999, The Journal of experimental medicine.

The Innate Immune Response to Salmonella enterica Serovar Typhimurium by Macrophages Is Dependent on TREM2-DAP12

A. Aderem, W. Seaman, Kelly D. Smith, 2008, Infection and Immunity.

Mouse Ly-49A Interrupts Early Signaling Events in Natural Killer Cell Cytotoxicity and Functionally Associates with the SHP-1 Tyrosine Phosphatase

W. Seaman, L. Shultz, J. Ryan, 1997, The Journal of experimental medicine.

Inhibitory Receptors Alter Natural Killer Cell Interactions with Target Cells Yet Allow Simultaneous Killing of Susceptible Targets

O. Axner, J. Ryan, C. Sentman, 1999, The Journal of experimental medicine.

Activating Ly-49 D and Inhibitory Ly-49 A Natural Killer Cell Receptors Demonstrate Distinct Requirements for Interaction with H 2-D d By

W. Seaman, S. Hayashi, J. Ryan, 2000 .

Activating Ly-49d and Inhibitory Ly-49a Natural Killer Cell Receptors Demonstrate Distinct Requirements for Interaction with H2-Dd

W. Seaman, S. Hayashi, J. Ryan, 2000, The Journal of experimental medicine.

Alloreactive Rat Natural Killer Cells Identification of an Inhibitory MHC Receptor on

J. Ryan, Mary C. Nakamura, J. Vaage, 1997 .

Role of ITAM‐containing adapter proteins and their receptors in the immune system and bone

L. Lanier, M. B. Humphrey, Mary C. Nakamura, 2005, Immunological reviews.

CMRF-35-Like Molecule-1, a Novel Mouse Myeloid Receptor, Can Inhibit Osteoclast Formation1

W. Seaman, D. Ginzinger, M. B. Humphrey, 2003, The Journal of Immunology.

Basic Aspects of Osteoclast Differentiation and Function

J. Charles, Mary C. Nakamura, N. Alesi, 2020 .

Chapter 25 – Pathogenesis of Inflammation-Induced Bone Loss

M. B. Humphrey, Mary C. Nakamura, M. Humphrey, 2006 .

CCR2 deficiency alters activation of microglia subsets in traumatic brain injury

G. Schmajuk, B. Zabel, J. Shigenaga, 2021, Cell reports.

A Comprehensive Review of Immunoreceptor Regulation of Osteoclasts

M. B. Humphrey, Mary C. Nakamura, M. Humphrey, 2016, Clinical Reviews in Allergy & Immunology.

Effect of Immunosuppression on the Immunogenicity of mRNA Vaccines to SARS-CoV-2

Gregory F. Wu, S. Whelan, D. Perantie, 2021, Annals of Internal Medicine.

The immunomodulatory adapter proteins DAP12 and Fc receptor γ-chain (FcRγ) regulate development of functional osteoclasts through the Syk tyrosine kinase

A. Mócsai, L. Lanier, A. Burghardt, 2004 .

Lower PDL1, PDL2, and AXL Expression on Lung Myeloid Cells Suggests In ﬂ ammatory Bias in Smoking and Chronic Obstructive Pulmonary Disease

Mary C. Nakamura, S. Zeng, M. Arjomandi, 2020 .

Clinical diagnosis of segmental arterial mediolysis: Differentiation from vasculitis and other mimics

K. Fye, Julie C. Baker-LePain, D. Stone, 2010, Arthritis care & research.

Bone Microenvironment Specific Roles of ITAM Adapter Signaling during Bone Remodeling Induced by Acute Estrogen-Deficiency

L. Lanier, N. Lane, Yalei Wu, 2007, PloS one.

TREM )-2 and DAP 12 Receptor Expressed on Myeloid Cells Responses in Macrophages by Triggering Cutting Edge : Inhibition of TLR and FcR

L. Lanier, W. Seaman, J. Hamerman, 2006 .

The Signaling Adapter Protein DAP12 Regulates Multinucleation During Osteoclast Development

L. Lanier, K. Ogasawara, W. Yao, 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Triggering Receptor Expressed on Myeloid Cells-2 Correlates to Hypothermic Neuroprotection in Ischemic Stroke.

M. Yenari, M. Kawabori, Christine L. Hsieh, 2013, Therapeutic hypothermia and temperature management.

Ligand interactions by activating and inhibitory Ly‐49 receptors

W. Seaman, Mary C. Nakamura, 2001, Immunological reviews.

Natural killer cells in immune regulation

Mary C. Nakamura, 1997 .

The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase.

A. Mócsai, L. Lanier, A. Burghardt, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Natural killer cells activated through NKG2D mediate lung ischemia-reperfusion injury.

J. Golden, L. Lanier, O. A. Aguilar, 2020, The Journal of clinical investigation.

Female-Specific Role of Progranulin to Suppress Bone Formation.

Liping Wang, R. Nissenson, Mary C. Nakamura, 2019, Endocrinology.

Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells—A potential mechanism for immune modulation

M. Matthay, Xiaohui Fang, Jae-Woo Lee, 2020, PloS one.

IL-10 Suppresses Calcium-Mediated Costimulation of Receptor Activator NF-κB Signaling during Human Osteoclast Differentiation by Inhibiting TREM-2 Expression1

L. Ivashkiv, J. Ji, M. B. Humphrey, 2009, The Journal of Immunology.

Expression Differentiation by Inhibiting TREM-2 Signaling during Human Osteoclast B κ Costimulation of Receptor Activator NF-IL-10 Suppresses Calcium-Mediated

L. Ivashkiv, J. Ji, Kyung-Hyun Park-Min, 2009 .

NF-κB/MAPK activation underlies ACVR1-mediated inflammation in human heterotopic ossification.

E. Hsiao, T. Ottenhoff, J. Hellman, 2018, JCI insight.

Cutting Edge: Inhibition of TLR and FcR Responses in Macrophages by Triggering Receptor Expressed on Myeloid Cells (TREM)-2 and DAP121

L. Lanier, W. Seaman, J. Hamerman, 2006, The Journal of Immunology.

Multiple roles for CCR2 during fracture healing

C. Colnot, D. Hu, T. Miclau, 2010, Disease Models & Mechanisms.

Pstpip2 Deficiency in Mice Causes Osteopenia and Increased Differentiation of Multipotent Myeloid Precursors into Osteoclasts Serum Levels of the Pro-osteoclastogenic Factor, Mip-1␣, Were Elevated and Csf-1 Receptor (csf-1r)–dependent Produc- Tion of Mip-1␣ by Macrophages Was In- Creased. Treatment

V. Nacu, H. McMahon, J. Charles, 2022 .

TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis

F. Brodsky, J. Cyster, W. Seaman, 2005, The Journal of experimental medicine.

Assessment of bone remodelling in childhood-onset systemic lupus erythematosus.

J. Shepherd, Julie C. Baker-LePain, E. von Scheven, 2011, Rheumatology.

CCR2 deficiency impairs macrophage infiltration and improves cognitive function after traumatic brain injury.

E. Huang, Jialing Liu, I. Charo, 2014, Journal of neurotrauma.

Traumatic brain injury induces macrophage subsets in the brain

Charles C. Kim, R. Locksley, W. Seaman, 2013, European journal of immunology.

Dendritic cell expression of A20 preserves immune homeostasis and prevents colitis and spondyloarthritis

E. Huang, L. Criswell, S. Oshima, 2011, Nature Immunology.

Non-catalytic ubiquitin binding by A20 prevents psoriatic arthritis–like disease and inflammation

P. Turnbaugh, Francis S. Kim, P. Achacoso, 2020, Nature Immunology.

Glucocorticoids and B Cell Depleting Agents Substantially Impair Immunogenicity of mRNA Vaccines to SARS-CoV-2

Gregory F. Wu, S. Whelan, D. Perantie, 2021, medRxiv.

The Origins of the Osteoclast

J. Charles, A. Aliprantis, Mary C. Nakamura, 2016 .

Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function.

A. Weiss, J. Charles, Lih-Yun Hsu, 2012, The Journal of clinical investigation.

A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia

W. Seaman, M. Yenari, Christine L. Hsieh, 2009, Journal of neurochemistry.

Effects of inflammation on bone: an update

N. Lane, Julie C. Baker-LePain, Mary C. Nakamura, 2011, Current opinion in rheumatology.

Bone and the Immune System (Osteoimmunology)

J. Charles, Mary C. Nakamura, M. Humphrey, 2019, Basic and Applied Bone Biology.

Targeting Nerve Growth Factor for Pain Management in Osteoarthritis-Clinical Efficacy and Safety.

N. Lane, Mary C. Nakamura, B. Dietz, 2021, Rheumatic diseases clinics of North America.

DAP12-mediated Signal Transduction in Natural Killer Cells

W. Seaman, S. Anderson, R. Geahlen, 1998, The Journal of Biological Chemistry.

Multicohort Analysis Identifies Monocyte Gene Signatures to Accurately Monitor Subset-Specific Changes in Human Diseases

Francesco Vallania, P. Khatri, J. Graf, 2021, Frontiers in Immunology.

Multicohort Analysis of Publicly-available Monocyte Expression Data Identifies Gene Signatures to Accurately Monitor Subset-specific Changes in Human Diseases

Francesco Vallania, P. Khatri, J. Graf, 2020, bioRxiv.

Bone and the Innate Immune System

J. Charles, Julia F Charles, Mary C Nakamura, 2014, Current Osteoporosis Reports.

Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Deficiency Attenuates Phagocytic Activities of Microglia and Exacerbates Ischemic Damage in Experimental Stroke

R. Kacimi, T. Kauppinen, M. Yenari, 2015, The Journal of Neuroscience.

Contemporary concepts of autoimmunity and autoimmune diseases

R. Nakamura, Mary C. Nakamura, 1992, Journal of clinical laboratory analysis.

D. Hu, T. Miclau, R. Marcucio, 2020, Aging cell.

Osteoimmunology: entwined regulation of integrated systems

Mary C. Nakamura, Mary C. Nakamura, 2019, Seminars in Immunopathology.

Effects of Aging on Fracture Healing

R. Marcucio, Mary C. Nakamura, T. Miclau, 2017, Current Osteoporosis Reports.

COVID-19 Breakthrough Infection Among Immunocompromised Persons.

Mary C. Nakamura, A. H. Kim, 2021, JAMA internal medicine.

ACVR1R206H extends inflammatory responses in human induced pluripotent stem cell-derived macrophages.

E. Hsiao, K. Tomoda, J. Hellman, 2021, Bone.

Immune Rejection of a Large Sarcoma Following Cyclophosphamide and IL-12 Treatment Requires Both NK and NK T Cells and Is Associated with the Induction of a Novel NK T Cell Population1

Mary C. Nakamura, E. Niemi, M. Daws, 2001, The Journal of Immunology.

Novel NK T Cell Population and Is Associated with the Induction of a Treatment Requires Both NK and NK T Cells Following Cyclophosphamide and IL-12 Immune Rejection of a Large Sarcoma

Mary C. Nakamura, E. Niemi, M. Daws, 2001 .

Mice Lacking the Integrin β5 Subunit Have Accelerated Osteoclast Maturation and Increased Activity in the Estrogen‐Deficient State

D. Sheppard, S. Teitelbaum, F. Ross, 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Non-catalytic ubiquitin binding by A20 prevents psoriatic arthritis-like disease and inflammation

P. Turnbaugh, Francis S. Kim, P. Achacoso, 2020, Nature Immunology.

Costimulatory blockade to prevent osteoclastogenesis, inflammation, or both?

J. Charles, Mary C. Nakamura, 2010 .

D. Hu, R. Marcucio, Mary C. Nakamura, 2022, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

D. Hu, R. Marcucio, Mary C. Nakamura, 2019, bioRxiv.

A receptor for vascular endothelial growth factor that stimulates endothelial apoptosis.

T. Quinn, L. Williams, S. Soifer, 2001, Cancer research.

Migration of IgA-bearing lymphocytes into salivary glands.

E. Lally, Mary C. Nakamura, P. C. Montgomery, 1981, Cellular immunology.

MHC class I molecules on adenovirus E1A-expressing tumor cells inhibit NK cell killing but not NK cell-mediated tumor rejection.

J. Ryan, M. Nakamura, Mary C. Nakamura, 2001, International immunology.