Matthew McMillin

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The Influence of Chronic Liver Diseases on Hepatic Vasculature: A Liver-on-a-chip Review

Danielle L. Stolley, T. Yankeelov, M. Rylander, 2020, Micromachines.

Inhibition of thrombospondin-1 reduces glutathione activity and worsens acute liver injury during acetaminophen hepatotoxicity in mice.

Matthew McMillin, Gabriel Frampton, P. Reddy, 2020, Toxicology and applied pharmacology.

Hepatic alterations are accompanied by changes to bile acid transporter-expressing neurons in the hypothalamus after traumatic brain injury

Suzanne Zeitouni, L. Shapiro, Matthew McMillin, 2017, Scientific Reports.

Thrombospondin-1 exacerbates acute liver failure and hepatic encephalopathy pathology in mice by activating transforming growth factor beta 1.

Matthew McMillin, S. DeMorrow, Gabriel Frampton, 2019, The American journal of pathology.

Cirrhosis and Inflammation Regulates CYP3A4 Mediated Chemoresistance in Vascularized Hepatocellular Carcinoma-on-a-chip

Danielle L. Stolley, T. Yankeelov, M. Rylander, 2022, bioRxiv.

The Direct Contribution of Astrocytes and Microglia to the Pathogenesis of Hepatic Encephalopathy

Matthew McMillin, S. DeMorrow, V. Jaeger, 2019, Journal of clinical and translational hepatology.

The specific serotonin reuptake inhibitors sertraline and fluoxetine promote tumor growth in a mouse xenograft model of cholangiocarcinoma

A. Petrescu, A. Wyatt, Matthew McMillin, 2017 .

Glucocorticoids Cause Gender-Dependent Reversal of Hepatic Fibrosis in the MDR2-Knockout Mouse Model

A. Petrescu, Matthew McMillin, S. DeMorrow, 2017, International journal of molecular sciences.

Gulf war illness-related chemicals increase CD11b/c+ monocyte infiltration into the liver and aggravate hepatic cholestasis in a rodent model

A. Shetty, A. Petrescu, Matthew McMillin, 2018, Scientific Reports.

Co-ordinated targeting of galanin receptors on cholangiocytes and hepatic stellate cells ameliorates liver fibrosis in Mdr2-knockout mice.

A. Petrescu, Matthew McMillin, S. DeMorrow, 2020, The American journal of pathology.

Bile Acid Signaling Is Involved in the Neurological Decline in a Murine Model of Acute Liver Failure.

Matthew McMillin, S. DeMorrow, Samir Ashfaq, 2016, The American journal of pathology.

Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms.

Matthew McMillin, S. DeMorrow, Gabriel Frampton, 2014, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Bile Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Promotes Neuroinflammation during Hepatic Encephalopathy in Mice

A. Petrescu, A. Wyatt, Matthew McMillin, 2017, Front. Cell. Neurosci..

Suppression of the HPA Axis During Cholestasis Can Be Attributed to Hypothalamic Bile Acid Signaling.

Matthew McMillin, S. DeMorrow, Gabriel Frampton, 2015, Molecular endocrinology.

TGFβ1 exacerbates blood–brain barrier permeability in a mouse model of hepatic encephalopathy via upregulation of MMP9 and downregulation of claudin-5

Matthew McMillin, S. DeMorrow, Gabriel Frampton, 2015, Laboratory Investigation.

Coordinated Targeting of Galanin Receptors on Cholangiocytes and Hepatic Stellate Cells Ameliorates Liver Fibrosis in Multidrug Resistance Protein 2 Knockout Mice

A. Petrescu, Matthew McMillin, S. DeMorrow, 2022 .

Overexpression of membrane metalloendopeptidase inhibits substance P stimulation of cholangiocarcinoma growth.

Debolina Ray, S. Glaser, J. Venter, 2014, American journal of physiology. Gastrointestinal and liver physiology.

Monoamine oxidase A expression is suppressed in human cholangiocarcinoma via coordinated epigenetic and IL-6-driven events

Xiao‐Yu Yin, Wei Chen, J. Lai, 2012, Laboratory Investigation.

Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism

L. Rimassa, P. Invernizzi, F. Bernuzzi, 2011, Gut.

Elevated circulating TGFβ1 during acute liver failure activates TGFβR2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice

A. Petrescu, Matthew McMillin, S. DeMorrow, 2019, Journal of Neuroinflammation.

Direct Comparison of the Thioacetamide and Azoxymethane Models of Type A Hepatic Encephalopathy in Mice.

A. Petrescu, Matthew McMillin, S. DeMorrow, 2018, Gene expression.

Fractalkine suppression during hepatic encephalopathy promotes neuroinflammation in mice

Matthew McMillin, S. DeMorrow, Gabriel Frampton, 2016, Journal of Neuroinflammation.

TGR5 signaling reduces neuroinflammation during hepatic encephalopathy

Matthew McMillin, S. DeMorrow, Gabriel Frampton, 2015, Journal of neurochemistry.

Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline

G. Alpini, Matthew McMillin, S. DeMorrow, 2014, Journal of Neuroinflammation.

The novel growth factor, progranulin, stimulates mouse cholangiocyte proliferation via sirtuin-1-mediated inactivation of FOXO1.

Y. Ueno, D. Leyva-Illades, Matthew McMillin, 2012, American journal of physiology. Gastrointestinal and liver physiology.

obstruction induces cholangiocyte proliferation in the rat Suppression of the HPA axis during extrahepatic biliary

Y. Ueno, Matthew McMillin, H. Francis, 2013 .

Suppression of the HPA axis during extrahepatic biliary obstruction induces cholangiocyte proliferation in the rat.

Y. Ueno, Matthew McMillin, S. DeMorrow, 2012, American journal of physiology. Gastrointestinal and liver physiology.

The Neuropeptide Galanin Is Up-Regulated during Cholestasis and Contributes to Cholangiocyte Proliferation.

Matthew McMillin, S. DeMorrow, Gabriel Frampton, 2017, The American journal of pathology.

Gonadotropin-releasing hormone stimulates biliary proliferation by paracrine/autocrine mechanisms.

Debolina Ray, R. Mancinelli, A. Franchitto, 2015, The American journal of pathology.

The Ammonia Hypothesis of Hepatic Encephalopathy should be Revisited

Matthew McMillin, S. DeMorrow, 2012 .

The Role of the Tumor Microenvironment in the Pathogenesis of Cholangiocarcinoma

Matthew McMillin, S. DeMorrow, Gabriel Frampton, 2012 .

Cholangiocarcinoma pathogenesis: Role of the tumor microenvironment.

D. Leyva-Illades, Matthew McMillin, S. DeMorrow, 2012, Translational gastrointestinal cancer.

Tumor Microenvironment Alters Chemoresistance of Hepatocellular Carcinoma Through CYP3A4 Metabolic Activity

Danielle L. Stolley, T. Yankeelov, M. Rylander, 2021, bioRxiv.

Acetaminophen‐induced liver injury in mice can be alleviated by reducing hepatic TGFβ1 signaling

A. Petrescu, Matthew McMillin, S. DeMorrow, 2018 .

The TGFβ1 receptor antagonist GW788388 reduces JNK activation and protects against acetaminophen hepatotoxicity in mice.

A. Petrescu, Matthew McMillin, S. DeMorrow, 2019, Toxicological sciences : an official journal of the Society of Toxicology.

Vascularized Hepatocellular Carcinoma on a Chip to Control Chemoresistance through Cirrhosis, Inflammation and Metabolic Activity

Danielle L. Stolley, T. Yankeelov, M. Nichole Rylander, 2023, Small Structures.

FXR-Mediated Cortical Cholesterol Accumulation Contributes to the Pathogenesis of Type A Hepatic Encephalopathy

A. Petrescu, Matthew McMillin, S. DeMorrow, 2018, Cellular and molecular gastroenterology and hepatology.

Gli1 activation and protection against hepatic encephalopathy is suppressed by circulating transforming growth factor β1 in mice.

Matthew McMillin, S. DeMorrow, Gabriel Frampton, 2014, Journal of hepatology.

Ghrelin reverses ductular reaction and hepatic fibrosis in a rodent model of cholestasis

A. Petrescu, Matthew McMillin, S. DeMorrow, 2020, Scientific Reports.

Neuroinflammatory Signals during Acute and Chronic Liver Diseases

Matthew McMillin, S. DeMorrow, 2017 .

Probiotics improve the neurometabolic profile of rats with chronic cholestatic liver disease

C. Cudalbu, Veronika Račkayová, V. McLin, 2021, Scientific Reports.

Effects of bile acids on neurological function and disease

Matthew McMillin, S. DeMorrow, 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Leptin enhances hepatic fibrosis and inflammation in a mouse model of cholestasis.

J. Venter, Nikhil Seth, A. Petrescu, 2021, The American journal of pathology.

The Role of Hypothalamic Neuropeptides in Regulation of Liver Functions in Health and Disease

J. Venter, A. Petrescu, Matthew McMillin, 2023, Endocrines.

Development and functional characterization of extrahepatic cholangiocyte lines from normal rats.

S. Glaser, J. Venter, G. Alpini, 2015, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Melatonin inhibits hypothalamic gonadotropin-releasing hormone release and reduces biliary hyperplasia and fibrosis in cholestatic rats.

S. Glaser, J. Venter, G. Alpini, 2017, American journal of physiology. Gastrointestinal and liver physiology.

Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline

G. Alpini, Matthew McMillin, S. DeMorrow, 2014, Journal of Neuroinflammation.

Liver and Biliary Tract Physiology/Pathophysiology Melatonin inhibits hypothalamic gonadotropin-releasing hormone release and reduces biliary hyperplasia and ﬁbrosis in cholestatic rats

S. Glaser, J. Venter, G. Alpini, 2017 .

Can Weather Influence the Prevalence of Acute-on-chronic Liver Failure?

Matthew McMillin, 2019, Journal of Clinical and Translational Hepatology.

Fractalkine suppression during hepatic encephalopathy promotes neuroinflammation in mice

Matthew McMillin, S. DeMorrow, Gabriel Frampton, 2016, Journal of Neuroinflammation.

Elevated circulating TGFβ1 during acute liver failure activates TGFβR2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice

A. Petrescu, Matthew McMillin, S. DeMorrow, 2019, Journal of Neuroinflammation.

The Role of the Tumor Microenvironment in the Pathogenesis of Cholangiocarcinoma

Matthew McMillin, S. DeMorrow, Gabriel Frampton, 2012 .

Faculty Opinions recommendation of Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ).

Matthew McMillin, S. DeMorrow, 2011 .

The Role of the Tumor Microenvironment in the Pathogenesis of Cholangiocarcinoma

Matthew McMillin, S. DeMorrow, Gabriel Frampton, 2012 .

Suppression of the HPA Axis During Cholestasis Can Be Attributed to Hypothalamic Bile Acid Signaling.

Matthew McMillin, S. DeMorrow, Gabriel Frampton, 2015, Molecular endocrinology.

Suppression of the HPA axis during extrahepatic biliary obstruction induces cholangiocyte proliferation in the rat.

Y. Ueno, Matthew McMillin, S. DeMorrow, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Melatonin inhibits hypothalamic gonadotropin-releasing hormone release and reduces biliary hyperplasia and fibrosis in cholestatic rats.

S. Glaser, J. Venter, G. Alpini, 2017, American journal of physiology. Gastrointestinal and liver physiology.