Jungjoon K. Lee

发表

Directed evolution of CRISPR-Cas9 to increase its specificity

Daesik Kim, Eunji Shin, Jin-Soo Kim, 2017 .

Increased expression of schizophrenia-associated gene C4 leads to hypoconnectivity of prefrontal cortex and reduced social interaction

A. Cruz-Martín, W. Yen, Jungjoon K. Lee, 2019, bioRxiv.

Design, Synthesis and Cytotoxicity Evaluation of Novel Indole Derivatives of Panaxadiol

H. Piao, Jungjoon K. Lee, Linlin Han, 2022, Chemistry & biodiversity.

Sniper2L is a high-fidelity Cas9 variant with high activity

Jin-Soo Kim, H. Kim, Seonwoo Min, 2023, Nature Chemical Biology.

Using Sniper-Cas9 to Minimize Off-target Effects of CRISPR-Cas9 Without the Loss of On-target Activity Via Directed Evolution.

M. Jung, Jungjoon K. Lee, Euihwan Jeong, 2019, Journal of visualized experiments : JoVE.

Directed evolution of CRISPR-Cas9 to increase its specificity

Daesik Kim, Eunji Shin, Kangin Lee, 2017, Nature Communications.

Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9

Jin-Soo Kim, Jin-Soo Kim, Taeyoung Koo, 2015, Molecules and cells.

Directed evolution of CRISPR-Cas9 to increase its specificity

Kangin Lee, Jin-Soo Kim, Daesik Kim, 2017, bioRxiv.

Single molecule analysis of effects of non-canonical guide RNAs and specificity-enhancing mutations on Cas9-induced DNA unwinding

T. Ha, M. Jung, J. Mallon, 2019, bioRxiv.

TAPE-seq is a cell-based method for predicting genome-wide off-target effects of prime editor

Jungjoon K. Lee, Jungjoon K Lee, Anna Jo, 2022, Nature Communications.

Extru-seq: a method for predicting genome-wide Cas9 off-target sites with advantages of both cell-based and in vitro approaches

Jin-Soo Kim, J. Hur, S. Bae, 2023, Genome Biology.

Synthesis and stability of small molecule probes for Pseudomonas aeruginosa quorum sensing modulation.

D. Spring, M. Welch, G. Salmond, 2004, Organic & biomolecular chemistry.

Functional identification of ligands for a catalytic metal ion in group I introns.

D. Herschlag, J. Piccirilli, Jihee Lee, 2008, Biochemistry.

Assessing the Predictive Ability of Computational Epitope Prediction Methods on Fel d 1 Allergen

Jungjoon K. Lee, Kyungsoo Ha, Yoonjoo Choi, 2023, bioRxiv.

Proceedings of the Chemical Society. January 1963

D. Spring, M. Welch, G. Salmond, 1963 .

Combining SELEX screening and rational design to develop light-up fluorophore-RNA aptamer pairs for RNA tagging.

Jianghong Rao, Fei Xiao, Jongho Jeon, 2010, ACS chemical biology.

Functional identification of ligands for a catalytic metal ion in group I introns.

D. Herschlag, J. Piccirilli, Jihee Lee, 2008, Biochemistry.