P. Keeney

发表

Parkinson's Disease Brain Mitochondrial Complex I Has Oxidatively Damaged Subunits and Is Functionally Impaired and Misassembled

J. Xie, J. Bennett, R. Capaldi, 2006, The Journal of Neuroscience.

ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions

J. Bennett, P. Keeney, 2010, Molecular Neurodegeneration.

Neurotoxic nitric oxide rapidly depolarizes and permeabilizes mitochondria by dynamically opening the mitochondrial transition pore☆

J. Bennett, N. Solenski, P. Keeney, 2003, Molecular and Cellular Neuroscience.

Micro RNA’s (mirna’s) may help explain expression of multiple genes in Alzheimer’s Frontal Cortex

J. Bennett, P. Keeney, 2017 .

Disrupted mitochondrial electron transport function increases expression of anti‐apoptotic Bcl‐2 and Bcl‐XL proteins in SH‐SY5Y neuroblastoma and in Parkinson disease cybrid cells through oxidative stress

C. Fall, R. Swerdlow, J. Bennett, 2000, Journal of neuroscience research.

Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model.

Kathleen M. Schwarz, J. Bennett, Shaharyar M. Khan, 2009, Human gene therapy.

Alzheimer's and Parkinson's Brain Tissues Have Reduced Expression of Genes for mtDNA OXPHOS Proteins, Mitobiogenesis Regulator PGC-1α Protein and mtRNA Stabilizing Protein LRPPRC (LRP130).

J. Bennett, P. Keeney, 2020, Mitochondrion.

Antibody types and IgG subclasses in paraneoplastic neurological syndromes

H. Brashear, J. Greenlee, P. Keeney, 2001, Journal of the Neurological Sciences.

Immunoenzymatic labelling of JC papovavirus T antigen in brains of patients with progressive multifocal leukoencephalopathy

J. Greenlee, P. Keeney, 2004, Acta Neuropathologica.

Localization of antibody in the central nervous system of a patient with paraneoplastic encephalomyeloneuritis

H. Brashear, P. Keeney, A. Heck, 1991, Neurology.

Mitochondrial Oxidative Phosphorylation Transcriptome Alterations in Human Amyotrophic Lateral Sclerosis Spinal Cord and Blood

J. Bennett, P. Keeney, A. Ladd, 2014, NeuroMolecular Medicine.

Immunofluorescent labelling of K-papovavirus antigens in glycol methacrylate embedded material: a method for studying infected cell populations by fluorescence microscopy and histological staining of adjacent sections.

J. Greenlee, P. Keeney, 1982, Stain technology.

Abnormal Mitochondrial Morphology in Sporadic Parkinson's and Alzheimer's Disease Cybrid Cell Lines

R. Swerdlow, J. Parks, J. Bennett, 2000, Experimental Neurology.

Methylpyridinium (MPP+)- and nerve growth factor-induced changes in pro- and anti-apoptotic signaling pathways in SH-SY5Y neuroblastoma cells

T. Sturgill, J. Bennett, P. Keeney, 2002, Brain Research.

Differentiation of Human Neural Stem Cells into Motor Neurons Stimulates Mitochondrial Biogenesis and Decreases Glycolytic Flux.

J. Bennett, P. Keeney, L. O’Brien, 2015, Stem cells and development.

Mitochondrial DNA copy numbers in pyramidal neurons are decreased and mitochondrial biogenesis transcriptome signaling is disrupted in Alzheimer's disease hippocampi.

J. Bennett, A. Rice, P. Keeney, 2014, Journal of Alzheimer's disease : JAD.

RNA Sequencing Reveals Small and Variable Contributions of Infectious Agents to Transcriptomes of Postmortem Nervous Tissues From Amyotrophic Lateral Sclerosis, Alzheimer’s Disease and Parkinson’s Disease Subjects, and Increased Expression of Genes From Disease-Activated Microglia

David G. Brohawn, J. Bennett, P. Keeney, 2019, Front. Neurosci..

Alzheimer's disease cybrids replicate β‐amyloid abnormalities through cell death pathways

R. Swerdlow, J. Parks, D. Cassarino, 2000 .

Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cells

J. Bennett, P. Keeney, Jeremy D. Rubinstein, 2008, Molecular Neurodegeneration.

Mitochondrial abnormalities in cybrid cell models of sporadic Alzheimer's disease worsen with passage in culture

R. Swerdlow, J. Bennett, W. Parker, 2004, Neurobiology of Disease.

Mitochondrial Oxidative Phosphorylation Transcriptome Alterations in Human Amyotrophic Lateral Sclerosis Spinal Cord and Blood

J. Bennett, P. Keeney, A. Ladd, 2014, NeuroMolecular Medicine.

Parkinson's disease brain mitochondria have impaired respirasome assembly, age-related increases in distribution of oxidative damage to mtDNA and no differences in heteroplasmic mtDNA mutation abundance

J. Bennett, P. Keeney, Lisa D. Dunham, 2009, Molecular Neurodegeneration.

Impaired complex-I mitochondrial biogenesis in Parkinson disease frontal cortex.

J. Bennett, P. Keeney, R. R. Thomas, 2012, Journal of Parkinson's disease.

RNA-seq analyses reveal that cervical spinal cords and anterior motor neurons from amyotrophic lateral sclerosis subjects show reduced expression of mitochondrial DNA-encoded respiratory genes, and rhTFAM may correct this respiratory deficiency

N. Tustison, David G. Brohawn, B. Kundu, 2017, Brain Research.

Relationships among molecular genetic and respiratory properties of Parkinson's disease cybrid cells show similarities to Parkinson's brain tissues.

J. Bennett, R. Capaldi, P. Keeney, 2009, Biochimica et biophysica acta.

Alzheimer's disease cybrids replicate beta-amyloid abnormalities through cell death pathways.

R. Swerdlow, J. Parks, D. Cassarino, 2000, Annals of neurology.

Parkinson's disease transgenic mitochondrial cybrids generate Lewy inclusion bodies

W. Parker, P. Keeney, P. Trimmer, 2004, Journal of neurochemistry.

RNA-Sequencing Reveals Similarities and Differences in Gene Expression in Vulnerable Brain Tissues of Alzheimer’s and Parkinson’s Diseases

J. Bennett, P. Keeney, 2018, Journal of Alzheimer's disease reports.

Cybrid models of Parkinson's disease show variable mitochondrial biogenesis and genotype-respiration relationships

J. Bennett, P. Keeney, Caitlin K. Quigley, 2009, Experimental Neurology.

1 Recombinant Human TFAM Stimulates Rat Brain , Rat Cervical Spinal Cord and Human Neural Stem Cell Mitochondrial Bioenergetics

N. Tustison, David G. Brohawn, B. Kundu, 2016 .

Mitochondrial DNA copy numbers in pyramidal neurons are decreased and mitochondrial biogenesis transcriptome signaling is disrupted in Alzheimer's disease hippocampi.

J. Bennett, A. Rice, P. Keeney, 2014, Journal of Alzheimer's disease : JAD.