Ashley V Menk

发表

Cutting Edge: Differential Regulation of PTEN by TCR, Akt, and FoxO1 Controls CD4+ T Cell Fate Decisions

James R Faeder, Natasa Miskov-Zivanov, Penelope A Morel, 2015, The Journal of Immunology.

Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion

Greg M. Delgoffe, Yiyang Wang, A. Poholek, 2021, Nature immunology.

Checkpoint molecules coordinately restrain hyperactivated effector T cells in the tumor microenvironment

Jingting Jiang, Greg M. Delgoffe, Chunyan He, 2020, Oncoimmunology.

Cutting Edge: Murine Mast Cells Rapidly Modulate Metabolic Pathways Essential for Distinct Effector Functions

L. Kane, Greg M. Delgoffe, Lyndsay Avery, 2017, The Journal of Immunology.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Manish R. Patel, Charles J. Vaske, Joe Y. Chang, 2016, Journal for Immunotherapy of Cancer.

512 Terminally exhausted CD8+ T cells potentiate the tolerogenic tumor microenvironment as functional suppressors

Greg M. Delgoffe, Ashley V Menk, Nicole E. Scharping, 2020, Journal for ImmunoTherapy of Cancer.

The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction.

Simon C Watkins, R. Ferris, Greg M. Delgoffe, 2016, Immunity.

Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ.

D. Stolz, R. Deshpande, Greg M. Delgoffe, 2019, Immunity.

Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted

M. Shlomchik, Ashley V. Menk, L. Kane, 2018, The Journal of clinical investigation.

Metabolic support of tumor-infiltrating regulatory T cells by lactic acid

J. Rothstein, Greg M. Delgoffe, B. Morrison, 2020, Nature.

Tumor hypoxia is associated with resistance to PD-1 blockade in squamous cell carcinoma of the head and neck

R. Ferris, Greg M. Delgoffe, D. Normolle, 2021, Journal for ImmunoTherapy of Cancer.

Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions

H. Young, Greg M. Delgoffe, S. Wendell, 2018, Cell reports.

The Lysophosphatidylcholine Transporter MFSD2A Is Essential for CD8+ Memory T Cell Maintenance and Secondary Response to Infection

Callen T. Wallace, Simon C Watkins, A. Cazenave-Gassiot, 2019, The Journal of Immunology.

Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity

Greg M. Delgoffe, S. Robson, A. Poholek, 2022, Nature Immunology.

Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion

Greg M. Delgoffe, Yiyang Wang, A. Poholek, 2021, Nature Immunology.

Tumor hypoxia drives suppressor function in exhausted T cells limiting antitumor immunity

Ashley V. Menk, Greg M. Delgoffe, Ashley V Menk, 2021, Journal for ImmunoTherapy of Cancer.

Lymphocyte Activation Gene-3 Maintains Mitochondrial and Metabolic Quiescence in Naive CD4+ T Cells.

Greg M. Delgoffe, Erin C O'Connor, Dana M Previte, 2019, Cell reports.

The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction.

Simon C Watkins, R. Ferris, Greg M. Delgoffe, 2016, Immunity.

Efficacy of PD-1 Blockade Is Potentiated by Metformin-Induced Reduction of Tumor Hypoxia

Ashley V. Menk, Greg M. Delgoffe, Ashley V Menk, 2016, Cancer Immunology Research.

4-1BB costimulation induces T cell mitochondrial function and biogenesis enabling cancer immunotherapeutic responses

Simon C Watkins, Michael J. Calderon, Greg M. Delgoffe, 2018, The Journal of experimental medicine.

IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell

Joe-Marc Chauvin, H. Zarour, V. Hornung, 2019, Cancer Immunology Research.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Charles J. Vaske, Rohan N. Borkar, Brian D. Kelly, 2016, Journal of Immunotherapy for Cancer.

Tumor cell oxidative metabolism as a barrier to PD-1 blockade immunotherapy in melanoma.

Y. Najjar, J. Kirkwood, Ashley V. Menk, 2019, JCI insight.

IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival

S. Gaffen, Greg M. Delgoffe, M. McGeachy, 2019, Nature Immunology.

Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis

M. Shlomchik, T. Winkler, W. Hawse, 2020, Nature Immunology.

IL-23 and IL-1β Drive Human Th17 Cell Differentiation and Metabolic Reprogramming in Absence of CD28 Costimulation.

Greg M. Delgoffe, M. McGeachy, A. Poholek, 2018, Cell reports.

IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival

Ashley V. Menk, S. Gaffen, Greg M. Delgoffe, 2019, Nature Immunology.

Oncolytic Viruses Engineered to Enforce Leptin Expression, Reprogram Tumor-Infiltrating T Cell Metabolism, and Promote Tumor Clearance.

R. Ferris, S. Thorne, Greg M. Delgoffe, 2019, Immunity.

Mesothelin-targeting T cells bearing a novel T cell receptor fusion construct (TRuC) exhibit potent antitumor efficacy against solid tumors

Guangwu Guo, P. Baeuerle, Greg M. Delgoffe, 2023, Oncoimmunology.

mTORC2 Deficiency Alters the Metabolic Profile of Conventional Dendritic Cells

Ryosuke Nakano, D. Stolz, Ashley V. Menk, 2019, Front. Immunol..

Excess dietary sugar impairs colonic epithelial regeneration in response to damage

V. Cooper, S. Beyaz, Lauren Mullinax, 2021, bioRxiv.

Oncolytic Viruses Enginee red to Enforce Leptin Expression Reprogram Tumor-Infiltrating T Cell Metabolism and Promote Tumor Clearance Graphical

R. Ferris, S. Thorne, Greg M. Delgoffe, 2019 .

Germinal center B cells selectively oxidize fatty acids for energy while conducting minimal glycolysis

M. Shlomchik, T. Winkler, W. Hawse, 2020, Nature Immunology.

Analyzing Melanoma Cell Oxygen Consumption and Extracellular Acidification Rates Using Seahorse Technology.

Greg M. Delgoffe, Ashley V Menk, 2021, Methods in molecular biology.

Tumor-Derived α-Fetoprotein Suppresses Fatty Acid Metabolism and Oxidative Phosphorylation in Dendritic Cells

Patricia M. Santos, L. Butterfield, Greg M. Delgoffe, 2019, Cancer Immunology Research.

Obesity is associated with altered tumor metabolism in metastatic melanoma.

Jared C Malke, Julie M Simon, D. Schadendorf, 2022, Clinical cancer research : an official journal of the American Association for Cancer Research.

The effect of opioids on the efficacy of immunotherapy in recurrent/metastatic squamous cell carcinoma of the head and neck.

R. Ferris, M. Nilsen, Greg M. Delgoffe, 2023, Oral oncology.

T Cell Fate Decisions + CD 4 PTEN by TCR , Akt , and FoxO 1 Controls Cutting Edge : Differential Regulation of

J. Faeder, W. Hawse, R. Sheehan, 2015 .

Metabolic reprogramming via an engineered PGC-1α improves human chimeric antigen receptor T-cell therapy against solid tumors

J. Lohmueller, Alok Kumar, Greg M. Delgoffe, 2023, Journal for ImmunoTherapy of Cancer.

Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to Damage

V. Cooper, S. Beyaz, Lauren Mullinax, 2023, Cellular and molecular gastroenterology and hepatology.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Charles J. Vaske, Joe Y. Chang, Scott R. Presnell, 2016, Journal for ImmunoTherapy of Cancer.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Charles J. Vaske, Rohan N. Borkar, David M. Schauder, 2016, Journal for ImmunoTherapy of Cancer.