Frank Speleman

发表

ViVar: A Comprehensive Platform for the Analysis and Visualization of Structural Genomic Variation

Tom Sante, Wigard P. Kloosterman, Sarah Vergult, 2014, PloS one.

Mutational dynamics between primary and relapse neuroblastomas

Sven Rahmann, Barbara Hero, Christopher Schröder, 2015, Nature Genetics.

Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11

Frank Speleman, Björn Menten, Wim Waelput, 2005, BMC Genomics.

Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification

Frank Speleman, Rogier Versteeg, Isabelle Janoueix-Lerosey, 2010, Clinical Cancer Research.

Comprehensive Analysis of Transcriptome Variation Uncovers Known and Novel Driver Events in T-Cell Acute Lymphoblastic Leukemia

Stein Aerts, Gert Hulselmans, Frank Speleman, 2013, PLoS genetics.

Neuroblastoma cells with overexpressed MYCN retain their capacity to undergo neuronal differentiation

Filip Pattyn, Frank Speleman, Jenny Karlsson, 2004, Laboratory Investigation.

External oligonucleotide standards enable cross laboratory comparison and exchange of real-time quantitative PCR data

Filip Pattyn, Frank Speleman, Jan Hellemans, 2009, Nucleic acids research.

Predicting outcomes for children with neuroblastoma.

Frank Speleman, Pieter Mestdagh, Jo Vandesompele, 2010, Discovery medicine.

Translocation–excision–deletion–amplification mechanism leading to nonsyntenic coamplification of MYC and ATBF1

Frank Speleman, Björn Menten, Jo Vandesompele, 2006, Genes, chromosomes & cancer.

Mate pair sequencing for the detection of chromosomal aberrations in patients with intellectual disability and congenital malformations

Edwin Cuppen, Tom Sante, Sarah Vergult, 2013, European Journal of Human Genetics.

The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma.

Francis Impens, Kris Gevaert, Frank Speleman, 2010, Molecular cell.

PHF6 mutations in T-cell acute lymphoblastic leukemia

Rob Pieters, Raul Rabadan, Frank Speleman, 2010, Nature Genetics.

Identification of ALK as a major familial neuroblastoma predisposition gene

John M. Maris, Nicholas J. Schork, Ali Torkamani, 2008, Nature.

Detection of DNA copy number alterations in cancer by array comparative genomic hybridization

Frank Speleman, Katleen De Preter, Nadine Van Roy, 2007 .

ArrayCGH‐based classification of neuroblastoma into genomic subgroups

Frank Speleman, Björn Menten, Rogier Versteeg, 2007, Genes, chromosomes & cancer.

Meta-mining of Neuroblastoma and Neuroblast Gene Expression Profiles Reveals Candidate Therapeutic Compounds

Filip Pattyn, Frank Speleman, Tom Van Maerken, 2009, Clinical Cancer Research.

Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study.

Ruth Ladenstein, Gudrun Schleiermacher, Gian Paolo Tonini, 2009, The Lancet. Oncology.

Real-time quantitative PCR as an alternative to Southern blot or fluorescence in situ hybridization for detection of gene copy number changes.

Frank Speleman, Jasmien Hoebeeck, Jo Vandesompele, 2007, Methods in molecular biology.

Impact of RNA quality on reference gene expression stability.

Frank Speleman, Claus Bachert, Jo Vandesompele, 2005, BioTechniques.

Elimination of primer-dimer artifacts and genomic coamplification using a two-step SYBR green I real-time RT-PCR.

Frank Speleman, Jo Vandesompele, Anne De Paepe, 2002, Analytical biochemistry.

Molecular Karyotyping: Array CGH Quality Criteria for Constitutional Genetic Diagnosis

Bart De Moor, Frank Speleman, Björn Menten, 2005, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

The αE-catenin gene (CTNNA1) acts as an invasion-suppressor gene in human colon cancer cells

Frank Speleman, Fransiska Malfait, F. Speleman, 1999, Oncogene.

A Multilocus Technique for Risk Evaluation of Patients with Neuroblastoma

Ruth Ladenstein, Gudrun Schleiermacher, Mario Drobics, 2011, Clinical Cancer Research.

Shallow Whole Genome Sequencing on Circulating Cell-Free DNA Allows Reliable Noninvasive Copy-Number Profiling in Neuroblastoma Patients

Tom Sante, Frank Speleman, Björn Menten, 2017, Clinical Cancer Research.

Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis

Philippe Debeer, Frank Speleman, Jan Hellemans, 2004, Nature Genetics.

Revised Risk Estimation and Treatment Stratification of Low- and Intermediate-Risk Neuroblastoma Patients by Integrating Clinical and Molecular Prognostic Markers

Roland Eils, Gudrun Schleiermacher, Barbara Hero, 2014, Clinical Cancer Research.

Prognostic impact of gene expression-based classification for neuroblastoma.

Roland Eils, Lars Kaderali, Gudrun Schleiermacher, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Imperfect protection: NEPA at 35 years.

Frank Speleman, Anne De Paepe, Jo Vandesompele, 2004, Genome Biology.

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia.

Fang Fang, Frank Speleman, Björn Menten, 2014, Blood.

Identification of an unbalanced X-autosome translocation by array CGH in a boy with a syndromic form of chondrodysplasia punctata brachytelephalangic type.

Frank Speleman, Björn Menten, Jo Vandesompele, 2005, European journal of medical genetics.

A novel and universal method for microRNA RT-qPCR data normalization

Frank Speleman, Pieter Mestdagh, Frank Westermann, 2009, Genome Biology.

Challenges for CNV interpretation in clinical molecular karyotyping: lessons learned from a 1001 sample experience.

Frank Speleman, Björn Menten, Bart Loeys, 2009, European journal of medical genetics.

Accurate Outcome Prediction in Neuroblastoma across Independent Data Sets Using a Multigene Signature

Gudrun Schleiermacher, John M. Maris, Benedikt Brors, 2010, Clinical Cancer Research.

Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25‐kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type 1 patients

Frank Speleman, Rogier Versteeg, Jo Vandesompele, 2002, Genes, chromosomes & cancer.

Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations

Yao-Cheng Lin, Jan Tavernier, Radoje Drmanac, 2014, Nature Communications.

Translating Expression Profiling into a Clinically Feasible Test to Predict Neuroblastoma Outcome

Roland Eils, Lars Kaderali, Benedikt Brors, 2007, Clinical Cancer Research.

The TLX1 oncogene drives aneuploidy in T-cell transformation

Andrea Califano, Frank Speleman, Susana Raimondi, 2010, Nature Medicine.

Overall genomic pattern is a predictor of outcome in neuroblastoma.

Gudrun Schleiermacher, Frank Speleman, Jérôme Couturier, 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Mapping biomedical concepts onto the human genome by mining literature on chromosomal aberrations

Bart De Moor, Yves Moreau, Joris Vermeesch, 2007, Nucleic acids research.

The microRNA body map: dissecting microRNA function through integrative genomics

Filip Pattyn, Frank Speleman, Pieter Mestdagh, 2011, Nucleic acids research.

Combined karyotyping, CGH and M‐FISH analysis allows detailed characterization of unidentified chromosomal rearrangements in Merkel cell carcinoma

Frank Speleman, Anne De Paepe, F. Speleman, 2002, International journal of cancer.

Unequivocal delineation of clinicogenetic subgroups and development of a new model for improved outcome prediction in neuroblastoma.

Michael Baudis, Holger Christiansen, Frank Speleman, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis

Frank Speleman, Robert A. Weinberg, Pieter Mestdagh, 2010, Nature Cell Biology.

Disease-Causing 7.4 kb Cis-Regulatory Deletion Disrupting Conserved Non-Coding Sequences and Their Interaction with the FOXL2 Promotor: Implications for Mutation Screening

Stylianos E. Antonarakis, Filip Pattyn, Frank Speleman, 2009, PLoS genetics.

A Constitutional Translocation t(1;17)(p36.2;q11.2) in a Neuroblastoma Patient Disrupts the Human NBPF1 and ACCN1 Genes

Frank Speleman, Jo Vandesompele, Karl Vandepoele, 2008, PloS one.

Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia

Rob Pieters, Frank Speleman, Peter Marynen, 2007, Nature Genetics.