D. E. Ruffner

发表

Oligoribonucleotide circularization by 'template-mediated' ligation with T4 RNA ligase: synthesis of circular hammerhead ribozymes.

L. Wang, D. E. Ruffner, Laixin Wang, 1998, Nucleic acids research.

Modified crush-and-soak method for recovering oligodeoxynucleotides from polyacrylamide gel.

D. E. Ruffner, Z. Chen, 1996, BioTechniques.

Molecular structure of the human albumin gene is revealed by nucleotide sequence within q11-22 of chromosome 4.

W. Kuang, W. Beattie, D. E. Ruffner, 1986, The Journal of biological chemistry.

Delivery of antisense oligonucleotides using HPMA polymer: synthesis of A thiol polymer and its conjugation to water-soluble molecules.

J. Kristensen, L. Wang, D. E. Ruffner, 1998, Bioconjugate chemistry.

Progress in the delivery of therapeutic oligonucleotides: organ/cellular distribution and targeted delivery of oligonucleotides in vivo.

R. K. Koehn, C. Stein, D. E. Ruffner, 2003, Antisense & nucleic acid drug development.

Accessing the Hidden Majority of Marine Natural Products through Metagenomics

M. Donia, E. Schmidt, D. E. Ruffner, 2011, Chembiochem : a European journal of chemical biology.

Structure and Evolution of the Serum Albumin Gene Family

P. E. Gibbs, D. E. Ruffner, A. Dugaiczyk, 1985 .

Splicing mutation in human hereditary analbuminemia.

D. E. Ruffner, A. Dugaiczyk, Duane E. Ruffner, 1988, Proceedings of the National Academy of Sciences of the United States of America.

An ultraviolet crosslink in the hammerhead ribozyme dependent on 2-thiocytidine or 4-thiouridine substitution.

L. Wang, D. E. Ruffner, 1997, Nucleic acids research.

Amplification of closed circular DNA in vitro.

D. E. Ruffner, Z. Chen, Zhidong Chen, 1998, Nucleic acids research.

Problems and Prospects in the Characterization of Posttranscriptional Modifications in Large RNAs

J. Rozenski, P. Crain, J. McCloskey, 2000 .

Invasion of the human albumin-alpha-fetoprotein gene family by Alu, Kpn, and two novel repetitive DNA elements.

P. E. Gibbs, D. E. Ruffner, C. N. Sprung, 1987, Molecular biology and evolution.

Ribozymes in Biotechnology

D. E. Ruffner, 2001 .

Sequence requirements of the hammerhead RNA self-cleavage reaction.

G D Stormo, G. Stormo, O. Uhlenbeck, 1990, Biochemistry.

Construction of a directed hammerhead ribozyme library: towards the identification of optimal target sites for antisense-mediated gene inhibition.

D. E. Ruffner, M. Pierce, 1998, Nucleic acids research.

Metabolic model for diversity-generating biosynthesis

Elizabeth Pierce, B. Bachmann, B. Olivera, 2016, Proceedings of the National Academy of Sciences.

Assessing the Combinatorial Potential of the RiPP Cyanobactin tru Pathway

E. Schmidt, John R. Heemstra, D. E. Ruffner, 2014, ACS synthetic biology.

Studies on the hammerhead RNA self-cleaving domain.

O. Uhlenbeck, O C Uhlenbeck, D E Ruffner, 1989, Gene.

Studies on the hammerhead RNA self-cleaving domain**Presented at the Albany Conference on ‘RNA: Catalysis, Splicing, Evolution’, Rensselaerville, NY (U.S.A.) 22-25 September 1988.

O. Uhlenbeck, D. E. Ruffner, S. C. Dahm, 1989 .

Thiophosphate interference experiments locate phosphates important for the hammerhead RNA self-cleavage reaction.

O. Uhlenbeck, D. E. Ruffner, 1990, Nucleic acids research.

Novel configurations of the hammerhead ribozyme: increased activity and reduced magnesium ion requirement.

L. Wang, D. E. Ruffner, 1998, Biochemical and biophysical research communications.