A. Machado

发表

Effects of short-term supplementation with folic acid on different oxidative stress parameters in patients with hypertension.

A. Ayala, S. Argüelles, P. Stiefel, 2005, Biochimica et biophysica acta.

Regional differences in the enhancement by GABA of [3H]zolpidem binding to ω1 sites in rat brain membranes and sections

J. Bénavidès, D. Ruano, J. Vitorica, 1993, Brain Research.

A preliminary analysis of within-subject variation in human serum oxidative stress parameters as a function of time.

A. Ayala, S. Argüelles, A. Machado, 2007, Rejuvenation research.

Effect of aging and oxidative stress on elongation factor-2 in hypothalamus and hypophysis

Antonio Ayala, M. Cano, A. Ayala, 2011, Mechanisms of Ageing and Development.

Effect of Oxidative Stress, Produced by Cumene Hydroperoxide, on the Various Steps of Protein Synthesis

J. Parrado, A. Ayala, A. Machado, 1996, The Journal of Biological Chemistry.

Effects of aging on the various steps of protein synthesis: fragmentation of elongation factor 2.

A. Castaño, J. Parrado, J. Parrado, 1999, Free radical biology & medicine.

Impairment of Mineralocorticoid Receptor (MR)-dependent Biological Response by Oxidative Stress and Aging

G. Piwien-Pilipuk, M. Galigniana, A. Ayala, 2002, The Journal of Biological Chemistry.

"In vitro" effect of cumene hydroperoxide on hepatic elongation factor-2 and its protection by melatonin.

J. Parrado, A. Ayala, A. Machado, 2003, Biochimica et biophysica acta.

Adduct formation of 4-hydroxynonenal and malondialdehyde with elongation factor-2 in vitro and in vivo.

A. Ayala, S. Argüelles, A. Machado, 2009, Free radical biology & medicine.

Direct quantitative determination of peptides and proteins in PVDF transfer membrane using a computing densitometer.

J. Parrado, A. Ayala, A. Machado, 1993, Peptide research.

Increased basal gluconeogenesis in the aged rat

J. Satrústegui, J. Cuezva, A. Machado, 1986, FEBS letters.

The pentose phosphate cycle is regulated by NADPH/NADP ratio in rat liver.

I. Fabregat, J. Vitorica, J. Satrústegui, 1985, Archives of biochemistry and biophysics.

Comparison of methods for sample preparation of individual rat cerebrospinal fluid samples prior to two-dimensional polyacrylamide gel electrophoresis

A. Ayala, A. Machado, S. García-Rodríguez, 2003, Biotechnology Letters.

The NADPH consumption regulates the NADPH-producing pathways (pentose phosphate cycle and malic enzyme) in rat adipocytes

I. Fabregat, A. Machado, E. Revilla, 1987, Molecular and Cellular Biochemistry.

Inhibition of fatty acid biosynthesis by bezafibrate in different rat cells.

I. Fabregat, C. Villanueva, A. Machado, 1989, Biochemical pharmacology.

Short-term control of the pentose phosphate cycle by insulin could be modulated by the NADPH/NADP ratio in rat adipocytes and hepatocytes.

I. Fabregat, A. Machado, E. Revilla, 1987, Biochemical and biophysical research communications.

NADPH/NADP ratio could regulate the glyoxylate cycle in Tetrahymena pyriformis

I. Fabregat, A. Machado, E. Revilla, 1987 .

The role of NADPH in the regulation of glucose-6-phosphate and 6-phosphogluconate dehydrogenases in rat adipose tissue

I. Fabregat, A. Ayala, A. Machado, 1991, Molecular and Cellular Biochemistry.

Possible involvement of NADPH requirement in regulation of Glucose-6-Phosphate and 6-Phosphogluconate dehydrogenase levels in rat liver

I. Fabregat, A. Ayala, A. Machado, 1990, Molecular and Cellular Biochemistry.

Involvement of diminution of glutathione, produced by deficiency of methionine in the diet, in the elevation of malic enzyme level in rat liver.

A. Castaño, A. Ayala, A. Machado, 1991, Biochimica et biophysica acta.

Do the serum oxidative stress biomarkers provide a reasonable index of the general oxidative stress status?

A. Ayala, S. Argüelles, Sonia García, 2004, Biochimica et biophysica acta.

J. Vitorica, J. Satrústegui, A. Machado, 1981, Neurochemical Research.

Impairment of glutamate uptake and absence of alterations in the energy-transducing ability of old rat brain mitochondria

J. Vitorica, J. Satrústegui, A. Machado, 1985, Mechanisms of Ageing and Development.

Comparative Study of the in Vitro Protective Effects of Several Antioxidants on Elongation Factor 2 under Oxidative Stress Conditions

M. Cano, A. Ayala, A. Machado, 2010, Bioscience, biotechnology, and biochemistry.

‘In vitro’ Protective Effect of a Hydrophilic Vitamin E Analogue on the Decrease in Levels of Elongation Factor 2 in Conditions of Oxidative Stress

A. Ayala, S. Argüelles, A. Machado, 2007, Gerontology.

Reduction of 1-methyl 1,2,3,4-tetrahydroisoquinoline level in substantia nigra of the aged rat

J. Cano, J. Parrado, A. Ayala, 1994, Brain Research.

Interaction with protein SH groups could be involved in adriamycin cardiotoxicity.

I. Fabregat, J. Satrústegui, A. Machado, 1984, Biochemical medicine.

Respiratory burst reaction changes with age in rat peritoneal macrophages.

A. Machado, C. Santa María, E. Alvarez, 1993, Biochimica et biophysica acta.

Myelin-like inclusions in maturing and senescent muscle cells of rat myocardium

J. Cano, A. Machado, J. Hervás, 1981, Mechanisms of Ageing and Development.

Comparison between developmental and senescent changes in enzyme activities linked to energy metabolism in rat heart

J. Cano, J. Vitorica, J. Satrústegui, 1981, Mechanisms of Ageing and Development.

Protective effect of melatonin against the 1‐methyl‐4‐phenylpyridinium‐induced inhibition of Complex I of the mitochondrial respiratory chain

J. Parrado, J. Parrado, A. Ayala, 2000, Journal of pineal research.

Hyperoxia and aging increase the guanylate cyclase activity of the rat lung

I. Fabregat, A. Machado, C. Santa María, 2006, AGE.

Constancy of the NADP-linked isocitrate dehydrogenase/transhydrogenase ratios of mitochondria of different mammalian tissues.

J. Satrústegui, E. Chico, A. Machado, 1978, Biochimie.

Correlation between circulating biomarkers of oxidative stress of maternal and umbilical cord blood at birth

A. Ayala, S. Argüelles, A. Machado, 2006, Free radical research.

Relationship between glyoxylate cycle activation and NADPH/NADP rise in Tetrahymena pyriformis.

J. Satrústegui, A. Machado, Jorgina Satrústegui, 1981, Biochimie.

Development of enzymes of energy metabolism in rat heart.

J. Satrústegui, A. Machado, A. Andrés, 1984, Biology of the neonate.

Implication of lysine residues in the loss of enzymatic activity in rat liver 6-phosphogluconate dehydrogenase found in aging.

J. Bautista, A. Ayala, A. Machado, 1989, The Journal of biological chemistry.

A convenient procedure for quantitative analysis of stained or immunostained blotting membranes by densitometry

J. Parrado, A. Ayala, A. Machado, 1995 .

Regulation by ammonium of glutamate dehydrogenase (NADP+) from Saccharomyces cerevisiae.

J. Satrústegui, A. Machado, E. Bogónez, 1985, Journal of general microbiology.

Malate dehydrogenase of Tetrahymena pyriformis: evolutionary and regulatory aspects

I. Fabregat, J. Satrústegui, A. Machado, 1984 .

Citrate synthase of Tetrahymena pyriformis: evolutionary and regulatory aspects.

I. Fabregat, J. Satrústegui, A. Machado, 1983, Archives of biochemistry and biophysics.

Use of rotofor preparative isoelectrofocusing cell in protein purification procedure

J. Parrado, J. Parrado, A. Ayala, 1998, Applied biochemistry and biotechnology.

Age-dependent modifications of rat heart succinate dehydrogenase

J. Satrústegui, A. Machado, M. Vélez, 1985, Mechanisms of Ageing and Development.

Changes in some hepatic enzyme activities related to phase II drug metabolism in male and female rats as a function of age

A. Machado, C. María, C. S. María, 1988, Mechanisms of Ageing and Development.

A. Machado, C. Santa María, C. S. María, 1986, Archives of gerontology and geriatrics.

Possible involvement of histidine residues in the loss of enzymatic activity of rat liver malic enzyme during aging.

J. Bautista, A. Ayala, A. Machado, 1988, The Journal of biological chemistry.

Relationship between enzymatic activity loss and post-translational protein modification in aging.

A. Ayala, A. Machado, C. Santa María, 1991, Archives of gerontology and geriatrics.

Malic enzyme levels are increased by the activation of NADPH‐consuming pathways: detoxification processes

A. Ayala, A. Machado, M. F-Lobato, 1986, FEBS letters.

Metabolic implications of ageing: changes in activities of key lipogenic and gluconeogenic enzymes in the aged rat liver.

J. Vitorica, J. Satrústegui, A. Machado, 1981, Enzyme.

Evidence suggesting that the NADPH/NADP ratio modulates the splitting of the isocitrate flux between the glyoxylic and tricarboxylic acid cycles, in Escherichia coli

J. Bautista, J. Satrústegui, A. Machado, 1979, FEBS letters.

Isocitrate dehydrogenase of Tetrahymena pyriformis

A. Machado, P. Vidal, 1977, Molecular and Cellular Biochemistry.

Age‐Dependent Variations in Peroxide‐Utilizing Enzymes from Rat Brain Mitochondria and Cytoplasm

J. Vitorica, J. Satrústegui, A. Machado, 1984, Journal of neurochemistry.

Ammonia accumulation in acetate-growing yeast.

J. Satrústegui, A. Machado, E. Bogónez, 1983, Biochimica et biophysica acta.

Sunflower peptones: use as nitrogen source for the formulation of fermentation media

J. Bautista, J. Parrado, F. Millán, 1993 .

Characterization of enzymic sunflower protein hydrolyzates

J. Bautista, J. Parrado, F. Millán, 1993 .

Production of soluble enzymic protein hydrolyzate from industrially defatted nondehulled sunflower meal

J. Bautista, J. Parrado, A. Machado, 1991 .

Increase of hyaluronate lyase productivity by repeated batch fermentation

J. Bautista, E. Chico, A. Machado, 1985, Biotechnology Letters.

Effects of discharged fraction in repeated batch culture for hyaluronate lyase production

J. Bautista, E. Chico, A. Machado, 1986 .

Isocitrate dehydrogenases and oxoglutarate dehydrogenase activities of baker's yeast grown in a variety of hypoxic conditions

F. Mayor, A. Machado, I. Núñez de Castro, 1975, Molecular and Cellular Biochemistry.

Development of NADPH-producing pathways in rat heart.

J. Satrústegui, A. Machado, A. Andrés, 1980, The Biochemical journal.

"In vitro" effect of lipid peroxidation metabolites on elongation factor-2.

A. Ayala, S. Argüelles, A. Machado, 2006, Biochimica et biophysica acta.

In vitro and in vivo protection by melatonin against the decline of elongation factor‐2 caused by lipid peroxidation: preservation of protein synthesis

M. Cano, A. Ayala, M. Muñoz, 2012, Journal of pineal research.

Induced mono-(ADP)-ribosylation of rat liver cytosolic proteins by lipid peroxidant agents.

J. Parrado, A. Ayala, A. Machado, 1999, Free radical biology & medicine.

Use of haptoglobin and transthyretin as potential biomarkers for the preclinical diagnosis of Parkinson's disease

J. Cano, J. L. Venero, S. Argüelles, 2010, Neurochemistry International.

One-step electroblotting of 2- to 100-kDa proteins onto a PVDF membrane

J. Parrado, A. Ayala, A. Machado, 1995 .

Effects of development and ageing on pulmonary NADPH-cytochrome c reductase, glutathione peroxidase, glutathione reductase and thioredoxin reductase activities in male and female rats

A. Machado, C. María, C. S. María, 1987, Mechanisms of Ageing and Development.

Cell removal from fermentation broth by flocculation + sedimentation

J. Bautista, E. Chico, A. Machado, 1986, Biotechnology Letters.

Low selenium diet increases the dopamine turnover in prefrontal cortex of the rat

J. Cano, A. Castaño, J. A. Rodríguez-Gómez, 1997, Neurochemistry International.

Effect of prenatal exposure to ethanol on hepatic elongation factor-2 and proteome in 21 d old rats: protective effect of folic acid.

A. Ayala, S. Argüelles, A. Machado, 2003, Free radical biology & medicine.

NADPH/NADP+ ratio: regulatory implications in yeast glyoxylic acid cycle

J. Bautista, J. Satrústegui, A. Machado, 2004, Molecular and Cellular Biochemistry.

Evidence for degradation in the carbon-starvation induced inactivation of yeast NADP-glutamate dehydrogenase

J. Satrústegui, A. Machado, E. Bogónez, 1979 .

Specific inactivation of NADP-dependent glutamate dehydrogenase from Saccharomyces cerevisiae

J. Satrústegui, A. Machado, 1978 .

The synthesis of yeast matrix mitochondrial enzymes is regulated by different levels of mitochondrial function.

J. Satrústegui, A. Machado, 1977, Archives of biochemistry and biophysics.

Age-dependent modification of lipid composition and lipid structural order parameter of rat peritoneal macrophage membranes

V. Ruíz-Gutiérrez, A. Machado, E. Alvarez, 1993, Mechanisms of Ageing and Development.

Synthesis of linalool and 4-terpineol from [14C]mevalonic acid in Pinus pinaster

F. Mayor, A. Machado, E. García-Peregrín, 1974 .

Variations due to hyperoxia and ageing in the activities of glutathione S-transferase and NADPH-cytochrome c reductase

J. Satrústegui, A. Machado, P. Blanco, 1987, Mechanisms of Ageing and Development.

Decrease of 1-methyl-1,2,3,4-tetrahydroisoquinoline synthesizing enzyme activity in the brain areas of aged rat

J. Parrado, A. Ayala, A. Machado, 2002, Brain Research.

Implication of lysine residues in the loss of 6-phosphogluconate dehydrogenase activity in aging human erythrocytes

A. Machado, E. Gordillo, 1991, Mechanisms of Ageing and Development.

Nitric oxide and superoxide anion production decrease with age in resident and activated rat peritoneal macrophages.

F. Sobrino, A. Machado, C. Santa María, 1996, Cellular Immunology.

Regulation of the level of yeasts citrate synthase by oxygen availability

F. Mayor, A. Machado, I. Castro, 1976, Molecular and Cellular Biochemistry.

Effect of inhibitors of mitochondrial protein synthesis on the NADH and NADPH glutamate dehydrogenases in yeast

F. Mayor, A. Machado, I. Núñez de Castro, 1974, Molecular and Cellular Biochemistry.

Succinic acid production by yeasts grown under different hypoxic conditions

J. A. Lupiáñez, F. Mayor, A. Machado, 1974, Molecular and Cellular Biochemistry.

Composition and fractionation of sunflower meal: use of the lignocellulosic fraction as substrate in solid-state fermentation.

J. Bautista, J. Parrado, Alberto Machado, 1990 .