A. Cannavo

发表

Molecular aspects of the cardioprotective effect of exercise in the elderly

D. Leosco, F. Giallauria, D. Liccardo, 2013, Aging Clinical and Experimental Research.

Sphingosine Kinases and Sphingosine 1-Phosphate Receptors: Signaling and Actions in the Cardiovascular System

W. Koch, D. Liccardo, G. Corbi, 2017, Front. Pharmacol..

GRK2 blockade with βARKct is essential for cardiac β2-adrenergic receptor signaling towards increased contractility

D. Leosco, W. Koch, D. Liccardo, 2013, Cell Communication and Signaling.

Targeting cardiac β-adrenergic signaling via GRK2 inhibition for heart failure therapy

W. Koch, D. Liccardo, A. Cannavo, 2013, Front. Physiol..

Negative Impact of &bgr;-Arrestin-1 on Post-Myocardial Infarction Heart Failure via Cardiac and Adrenal-Dependent Neurohormonal Mechanisms

D. Leosco, W. Koch, D. Liccardo, 2014, Hypertension.

Impact of diabetes mellitus on lymphocyte GRK2 protein levels in patients with heart failure

F. Rengo, D. Leosco, B. Trimarco, 2015, European journal of clinical investigation.

Novel missense mutations and unexpected multiple changes of RYR1 gene in 75 malignant hyperthermia families

G. Piluso, G. Savoia, V. Nigro, 2011, Clinical genetics.

Genetic Deletion of Uncoupling Protein 3 Exaggerates Apoptotic Cell Death in the Ischemic Heart Leading to Heart Failure

C. Indolfi, A. Sannino, B. Trimarco, 2013, Journal of the American Heart Association.

Sex Differences in Cardiovascular Diseases: A Matter of Estrogens, Ceramides, and Sphingosine 1-Phosphate

D. Liccardo, A. Rapacciuolo, G. Corbi, 2022, International journal of molecular sciences.

Reduction of lymphocyte G protein-coupled receptor kinase-2 (GRK2) after exercise training predicts survival in patients with heart failure

P. Filardi, D. Leosco, F. Giallauria, 2014, European journal of preventive cardiology.

The Adrenergic System of the Myocardium

N. Ferrara, G. Rengo, G. Pagano, 2015 .

&bgr;1-Adrenergic Receptor and Sphingosine-1-Phosphate Receptor 1 (S1PR1) Reciprocal Downregulation Influences Cardiac Hypertrophic Response and Progression to Heart Failure: Protective Role of S1PR1 Cardiac Gene Therapy

T. Palmer, D. Leosco, M. Barone, 2013, Circulation.

Alteration of myocardial GRK2 produces a global metabolic phenotype.

W. Koch, K. Drosatos, J. K. Chuprun, 2014, JCI insight.

EGFR trans-activation by urotensin II receptor is mediated by β-arrestin recruitment and confers cardioprotection in pressure overload-induced cardiac hypertrophy

P. Grieco, C. Indolfi, M. Chiariello, 2011, Basic Research in Cardiology.

Risk of acute myocardial infarction after transurethral resection of prostate in elderly

D. Leosco, D. Liccardo, P. Iacotucci, 2013, BMC Surgery.

β Adrenergic Receptor Kinase C-Terminal Peptide Gene-Therapy Improves β2-Adrenergic Receptor-Dependent Neoangiogenesis after Hindlimb Ischemia

F. Rengo, D. Leosco, W. Koch, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Targeting β3-Adrenergic Receptors in the Heart: Selective Agonism and β-Blockade

W. Koch, A. Cannavo, 2016, Journal of cardiovascular pharmacology.

Aldosterone Jeopardizes Myocardial Insulin and β-Adrenergic Receptor Signaling via G Protein-Coupled Receptor Kinase 2

W. Koch, D. Liccardo, A. Rapacciuolo, 2019, Front. Pharmacol..

Prothymosin alpha protects cardiomyocytes against ischemia-induced apoptosis via preservation of Akt activation

D. Leosco, M. Ferrone, W. Koch, 2013, Apoptosis.

Vascular Endothelial Growth Factor Blockade Prevents the Beneficial Effects of &bgr;-Blocker Therapy on Cardiac Function, Angiogenesis, and Remodeling in Heart Failure

D. Leosco, W. Koch, B. Trimarco, 2013, Circulation. Heart failure.

Blockade of β‐adrenoceptors restores the GRK2‐mediated adrenal α2‐adrenoceptor–catecholamine production axis in heart failure

P. Gargiulo, D. Leosco, D. Liccardo, 2012, British journal of pharmacology.

Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine.

J. Cheung, W. Koch, J. Tesmer, 2017, Journal of medicinal chemistry.

GRK2 Regulates α2-Adrenergic Receptor-Dependent Catecholamine Release in Human Adrenal Chromaffin Cells.

D. Leosco, W. Koch, D. Liccardo, 2017, Journal of the American College of Cardiology.

G-Protein-Coupled Receptors and Their Kinases in Cardiac Regulation

W. Koch, A. Cannavo, C. Lucia, 2016 .

β1-Blockade Prevents Post-Ischemic Myocardial Decompensation Via β3AR-Dependent Protective Sphingosine-1 Phosphate Signaling.

D. Leosco, W. Koch, B. Ibáñez, 2017, Journal of the American College of Cardiology.

Aldosterone and Myocardial Pathology.

W. Koch, D. Liccardo, G. Rengo, 2019, Vitamins and hormones.

Gene therapy for heart disease: molecular targets, vectors and modes of delivery to myocardium

W. Koch, M. Scimia, A. Cannavo, 2013, Expert review of cardiovascular therapy.

Chronic β1-adrenergic blockade enhances myocardial β3-adrenergic coupling with nitric oxide-cGMP signaling in a canine model of chronic volume overload: new insight into mechanisms of cardiac benefit with selective β1-blocker therapy

S. Houser, J. Balligand, F. Recchia, 2014, Basic Research in Cardiology.

Chapter 2 The Adrenergic System of the Myocardium

N. Ferrara, G. Rengo, G. Pagano, 2018 .

GRK2 compromises cardiomyocyte mitochondrial function by diminishing fatty acid-mediated oxygen consumption and increasing superoxide levels.

W. Koch, K. Drosatos, J. Elrod, 2015, Journal of molecular and cellular cardiology.

Burning Redoxstats in the Brainstem: Lack of Nrf2 and the Rise of Hypertension.

N. Montano, N. Paolocci, A. Cannavo, 2017, Hypertension.

β 1 -Adrenergic Receptor and Sphingosine-1-Phosphate Receptor 1 (S1PR1) Reciprocal Downregulation Influences Cardiac Hypertrophic Response and Progression to Heart Failure Protective Role of S1PR1 Cardiac Gene Therapy Heart Failure

Maria Carmen De Angelis, T. Palmer, D. Leosco, 2013 .

Sex/Gender- and Age-Related Differences in β-Adrenergic Receptor Signaling in Cardiovascular Diseases

D. Liccardo, G. Corbi, B. Arosio, 2022, Journal of clinical medicine.

G Protein-Coupled Receptor and Their Kinases in Cell Biology and Disease

A. Cannavo, 2022, International journal of molecular sciences.

β ARKct gene-therapy improves β 2-adrenergic receptor-dependent neoangiogenesis following hindlimb ischemia

F. Rengo, D. Leosco, W. Koch, 2015 .

β-adrenergic receptors and G protein-coupled receptor kinase-2 in Alzheimer's disease: a new paradigm for prognosis and therapy?

P. Filardi, D. Leosco, C. Vigorito, 2013, Journal of Alzheimer's disease : JAD.

Genetic Catalytic Inactivation of GRK5 Impairs Cardiac Function in Mice Via Dysregulated P53 Levels

W. Koch, D. Liccardo, A. Rapacciuolo, 2022, JACC. Basic to translational science.

Eating Away at Heart Failure.

W. Koch, A. Cannavo, 2015, Journal of the American College of Cardiology.

Is the Hitman in Cardiac Death Hidden in the Sympathetic Nervous System Remodeling?

G. Rengo, G. Pagano, A. Cannavo, 2020, Journal of the American College of Cardiology.

Are Skeletal Muscle Changes during Prolonged Space Flights Similar to Those Experienced by Frail and Sarcopenic Older Adults?

E. Tobaldini, N. Montano, G. Corbi, 2022, Life.

Periodontal Disease: A Risk Factor for Diabetes and Cardiovascular Disease

G. Spagnuolo, D. Liccardo, N. Ferrara, 2019, International journal of molecular sciences.

GRK2 blockade with βARKct is essential for cardiac β2-adrenergic receptor signaling towards increased contractility

D. Leosco, W. Koch, D. Liccardo, 2013, Cell Communication and Signaling.

microRNA in Cardiovascular Aging and Age-Related Cardiovascular Diseases

S. Houser, W. Koch, G. Corbi, 2017, Front. Med..

Potential Bidirectional Relationship Between Periodontitis and Alzheimer’s Disease

M. Guida, D. Liccardo, N. Ferrara, 2020, Frontiers in Physiology.

Differential Role of G Protein-Coupled Receptor Kinase 5 in Physiological Versus Pathological Cardiac Hypertrophy.

Yan Zhou, W. Koch, E. Gao, 2015, Circulation research.

Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.

J. Cheung, W. Koch, P. Kirchhoff, 2016, Journal of medicinal chemistry.

Atrial fibrillation in the elderly: a risk factor beyond stroke

G. Corbi, N. Ferrara, A. Cittadini, 2020, Ageing Research Reviews.

Increased Epicardial Adipose Tissue Volume Correlates With Cardiac Sympathetic Denervation in Patients With Heart Failure.

D. Leosco, M. Nolano, N. Ferrara, 2016, Circulation research.

Impact of aging on cardiac sympathetic innervation measured by 123I-mIBG imaging in patients with systolic heart failure

P. Filardi, D. Leosco, B. Trimarco, 2016, European Journal of Nuclear Medicine and Molecular Imaging.

Prognostic Value of Lymphocyte G Protein-Coupled Receptor Kinase-2 Protein Levels in Patients With Heart Failure.

P. Filardi, D. Leosco, W. Koch, 2016, Circulation research.

Aldosterone and Mineralocorticoid Receptor System in Cardiovascular Physiology and Pathophysiology

D. Liccardo, N. Ferrara, N. Paolocci, 2018, Oxidative medicine and cellular longevity.

Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases

D. Leosco, W. Koch, D. Liccardo, 2016, Nature Communications.

Editorial: Molecular Mechanisms Involved in Heart Failure, Parkinson’s, and Alzheimer’s Diseases

D. Liccardo, G. Pagano, A. Cannavo, 2021, Frontiers in Molecular Biosciences.

Changes of plasma norepinephrine and serum N-terminal pro-brain natriuretic peptide after exercise training predict survival in patients with heart failure.

D. Leosco, W. Koch, D. Liccardo, 2014, International journal of cardiology.

Targeting GRK5 for Treating Chronic Degenerative Diseases

W. Koch, A. Rapacciuolo, N. Ferrara, 2021, International journal of molecular sciences.

GRK2 as a therapeutic target for heart failure

D. Liccardo, N. Ferrara, G. Rengo, 2018, Expert opinion on therapeutic targets.

Infective Endocarditis: A Focus on Oral Microbiota

G. Spagnuolo, D. Liccardo, N. Ferrara, 2021, Microorganisms.

GRK2 as negative modulator of NO bioavailability: Implications for cardiovascular disease.

W. Koch, A. Cannavo, 2018, Cellular signalling.

Predisposing factors to heart failure in diabetic nephropathy: a look at the sympathetic nervous system hyperactivity

D. Leosco, G. Corbi, N. Ferrara, 2018, Aging Clinical and Experimental Research.

Galectins can serve as biomarkers in COVID-19: A comprehensive systematic review and meta-analysis

A. Cannavo, A. Kalantari, C. Dimitroff, 2023, Frontiers in Immunology.

Why Do We Not Assess Sympathetic Nervous System Activity in Heart Failure Management: Might GRK2 Serve as a New Biomarker?

G. Rengo, K. Komici, A. Cannavo, 2021, Cells.

Crystal Structure of G Protein-coupled Receptor Kinase 5 in Complex with a Rationally Designed Inhibitor*♦

J. Cheung, W. Koch, J. Tesmer, 2015, The Journal of Biological Chemistry.

β3AR-Dependent Brain-Derived Neurotrophic Factor (BDNF) Generation Limits Chronic Postischemic Heart Failure

L. Finos, W. Koch, D. Liccardo, 2023, Circulation research.

Beta-3 adrenergic receptor overexpression reverses aortic stenosis–induced heart failure and restores balanced mitochondrial dynamics

V. Fuster, J. L. de la Pompa, W. Koch, 2022, Basic Research in Cardiology.

Identification and Characterization of Amlexanox as a G Protein-Coupled Receptor Kinase 5 Inhibitor

W. Koch, J. Tesmer, A. Cannavo, 2014, Molecules.

Induction of Mitogen-Activated Protein Kinases Is Proportional to the Amount of Pressure Overload

Cinzia Perrino, Raffaele Izzo, Anna Sannino, 2010, Hypertension.

Relationship between COVID-19 Mortality, Hospital Beds, and Primary Care by Italian Regions: A Lesson for the Future

S. Cocozza, V. Conti, G. Corbi, 2022, Journal of clinical medicine.

Healthy aging: when periodontal health matters

G. Spagnuolo, D. Liccardo, G. Corbi, 2023, Journal of Gerontology and Geriatrics.

Prothymosin alpha protects cardiomyocytes against ischemia-induced apoptosis via preservation of Akt activation

D. Leosco, M. Ferrone, W. Koch, 2013, Apoptosis.

Equol and Resveratrol Improve Bone Turnover Biomarkers in Postmenopausal Women: A Clinical Trial

V. Conti, G. Corbi, G. Scapagnini, 2023, International journal of molecular sciences.

Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein–Coupled Receptor Kinase 2 Inhibitors

J. Cheung, Xin-Qiu Yao, W. Koch, 2017, Molecular Pharmacology.

Endocan as a marker of endothelial dysfunction in hypertension: a systematic review and meta-analysis

Parnian Shobeiri, A. Cannavo, A. Behnoush, 2023, Hypertension Research.

Aging is associated with cardiac autonomic nerve fiber depletion and reduced cardiac and circulating BDNF levels

R. Kishore, N. Ferrara, N. Paolocci, 2021, Journal of geriatric cardiology : JGC.