C. Coderch

发表

Comparative Binding Energy (COMBINE) Analysis for Understanding the Binding Determinants of Type II Dehydroquinase Inhibitors

F. Gago, C. González‐Bello, Antonio Peón, 2013, ChemMedChem.

Design and synthesis of novel dual-target agents for HDAC1 and CK2 inhibition

R. Panchuk, A. Ramos, C. Coderch, 2016 .

Comparative Binding Energy (COMBINE) Analysis Supports a Proposal for the Binding Mode of Epothilones to β‐Tubulin

F. Gago, A. Morreale, J. F. Díaz, 2012, ChemMedChem.

Multitarget Anticancer Agents Based on Histone Deacetylase and Protein Kinase CK2 Inhibitors

R. Panchuk, M. Masłyk, B. de Pascual-Teresa, 2020, Molecules.

Mechanistic Insight into the Catalytic Activity of ββα‐Metallonucleases from Computer Simulations: Vibrio vulnificus Periplasmic Nuclease as a Test Case

J. Bueren-Calabuig, F. Gago, A. Jiménez-Ruiz, 2011, Chembiochem : a European journal of chemical biology.

Pharmacological inhibition of Receptor Protein Tyrosine Phosphatase β/ζ (PTPRZ1) modulates behavioral responses to ethanol

M. Vicente-Rodríguez, C. Coderch, B. Pascual-Teresa, 2018, Neuropharmacology.

Development of inhibitors of receptor protein tyrosine phosphatase β/ζ (PTPRZ1) as candidates for CNS disorders.

A. Pineda-Lucena, M. Vicente-Rodríguez, B. de Pascual-Teresa, 2018, European journal of medicinal chemistry.

A structure-based design of new C2- and C13-substituted taxanes: tubulin binding affinities and extended quantitative structure-activity relationships using comparative binding energy (COMBINE) analysis.

F. Gago, A. Morreale, J. Klett, 2013, Organic & biomolecular chemistry.

Molecular Imaging Probes Based on Matrix Metalloproteinase Inhibitors (MMPIs)

B. de Pascual-Teresa, L. Rangasamy, C. Coderch, 2019, Molecules.

Synthesis and biological evaluation of a new series of highly functionalized 7'-homo-anhydrovinblastine derivatives.

F. Gago, J. Bignon, F. Roussi, 2013, Journal of medicinal chemistry.

One-pot synthesis of vinca alkaloids-phomopsin hybrids.

F. Gago, J. Bignon, F. Roussi, 2014, Journal of medicinal chemistry.

Tubulin-based structure-affinity relationships for antimitotic Vinca alkaloids.

F. Gago, A. Morreale, C. Coderch, 2012, Anti-cancer agents in medicinal chemistry.

Optimization of taxane binding to microtubules: binding affinity dissection and incremental construction of a high-affinity analog of paclitaxel.

Federico Gago, F. Gago, I. Barasoain, 2008, Chemistry & biology.

Synthesis, biological activity and structural study of new benzotriazole-based protein kinase CK2 inhibitors

R. Panchuk, M. Masłyk, A. Ramos, 2015 .

Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach.

I. Paterson, C. Trigili, Á. Canales, 2011, ACS chemical biology.

Discovery of potent calpain inhibitors based on the azolo-imidazolidenone scaffold.

M. Morón, D. Rodríguez‐Puyol, M. Rodríguez‐Puyol, 2018, European journal of medicinal chemistry.

Molecular recognition of epothilones by microtubules and tubulin dimers revealed by biochemical and NMR approaches.

K. Altmann, F. Gago, T. Carlomagno, 2014, ACS chemical biology.

New Dual CK2/HDAC1 Inhibitors with Nanomolar Inhibitory Activity against Both Enzymes.

B. de Pascual-Teresa, L. Rangasamy, C. Coderch, 2020, ACS medicinal chemistry letters.

Identification of aldo-keto reductase AKR1B10 as a selective target for modification and inhibition by prostaglandin A(1): implications for antitumoral activity.

F. Gago, J. Timms, Beatriz Díez-Dacal, 2011, Cancer research.

Proteasomal Degradation of Zn-Dependent Hdacs: The E3-Ligases Implicated and the Designed Protacs That Enable Degradation

B. de Pascual-Teresa, C. Coderch, A. Ramos, 2021, Molecules.

The Many Ways to Deal with STING

B. de Pascual-Teresa, C. Coderch, Estanislao Nistal-Villán, 2023, International journal of molecular sciences.

Design and Synthesis of Water-Soluble and Potent MMP-13 Inhibitors with Activity in Human Osteosarcoma Cells

A. Pineda-Lucena, Pilar Ramos, B. de Pascual-Teresa, 2021, International journal of molecular sciences.

Design and synthesis of potent hydroxamate inhibitors with increased selectivity within the gelatinase family.

B. de Pascual-Teresa, C. Coderch, Kamila Filipiak, 2015, Organic & biomolecular chemistry.

Mechanistic insight into the reaction catalysed by bacterial type II dehydroquinases.

F. Gago, A. Hawkins, C. González‐Bello, 2014, The Biochemical journal.

In silico identification and in vivo characterization of small molecule therapeutic hypothermia mimetics.

Alfredo Martínez, B. de Pascual-Teresa, I. Larráyoz, 2017, Bioorganic & medicinal chemistry.

Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach.

I. Paterson, C. Trigili, Á. Canales, 2011, ACS chemical biology.

New clicked thiirane derivatives as gelatinase inhibitors: the relevance of the P1′ segment

A. Pineda-Lucena, A. Ramos, A. Schott, 2014 .

From a MMP2/CK2 multitarget approach to the identification of potent and selective MMP13 inhibitors.

R. Panchuk, B. de Pascual-Teresa, C. Coderch, 2019, Organic & biomolecular chemistry.