H. Yamaguchi

发表

Molecular docking and structural analysis of cofactor-protein interaction between NAD+ and 11β-hydroxysteroid dehydrogenase type 2

K. Ryoyama, T. Akitaya, H. Yamaguchi, 2012, Journal of Molecular Modeling.

Isolation of Ursolic Acid from Apple Peels and Its Specific Efficacy as a Potent Antitumor Agent

M. Hayashi, K. Ryoyama, K. Komiyama, 2008 .

Development of a credible 3D-QSAR CoMSIA model and docking studies for a series of triazoles and tetrazoles containing 11β-HSD1 inhibitors

P. Miniyar, P. Murumkar, M. Yadav, 2016, SAR and QSAR in environmental research.

Anti-Tumor Activity of an Enzymatically Synthesized α-1,6 Branched α-1,4-Glucan, Glycogen

H. Takata, K. Ryoyama, H. Yamaguchi, 2004 .

Mouse 11β-Hydroxysteroid Dehydrogenase Type 2 for Human Application: Homology Modeling, Structural Analysis and Ligand-Receptor Interaction

K. Ryoyama, T. Akitaya, H. Yamaguchi, 2011, Cancer informatics.

Intracellular accumulation of structurally varied isothiocyanates correlates with inhibition of nitric oxide production in proinflammatory stimuli-activated tumorigenic macrophage-like cells.

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2014, Bioorganic & medicinal chemistry.

6-(methylsulfinyl)hexyl isothiocyanate (6-MITC) from Wasabia japonica alleviates inflammatory bowel disease (IBD) by potential inhibition of glycogen synthase kinase 3 beta (GSK-3β).

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2021, European journal of medicinal chemistry.

Inhibition of 11 b-hydroxysteroid dehydrogenase 2 by the fungicides itraconazole and posaconazole

A. Odermatt, D. Schuster, V. Temml, 2017 .

Increased synthesis of GFAP by TCDD in differentiation-disrupted SFME cells.

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2003, Environmental toxicology and pharmacology.

Detection of 6-(methylsulfinyl)hexyl isothiocyanate (6-MITC) and its conjugate with N-acetyl-L-cysteine (NAC) by high performance liquid chromatograpy-atmospheric pressure chemical ionization mass spectrometry (HPLC-MS/APCI).

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2008, Chemical & pharmaceutical bulletin.

11β-Hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor γ[S]

Silvia G. Inderbinen, A. Odermatt, D. Kratschmar, 2019, Journal of Lipid Research.

Toluene at Environmentally Relevant Low Levels Disrupts Differentiation of Astrocyte Precursor Cells

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2002, Archives of environmental health.

Interferon‐gamma and lipopolysaccharide stimulation increases matrix metalloproteinase‐9 expression and enhances invasion activity in ras/myc‐transformed serum‐free mouse embryo cells

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2007, Cell biology international.

Ras/myc-transformed serum-free mouse embryo cells under simulated inflammatory and infectious conditions increase levels of nitric oxide and matrix metalloproteinase-9 without a direct association between them

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2007, Molecular and Cellular Biochemistry.

Enzymatic interconversion of the oxysterols 7β,25-dihydroxycholesterol and 7-keto,25-hydroxycholesterol by 11β-hydroxysteroid dehydrogenase type 1 and 2

A. Odermatt, K. Seuwen, D. Kratschmar, 2019, The Journal of Steroid Biochemistry and Molecular Biology.

Novel effects of glycyrrhetinic acid on the central nervous system tumorigenic progenitor cells: induction of actin disruption and tumor cell-selective toxicity.

K. Ryoyama, H. Yamaguchi, Tao Yu, 2010, European journal of medicinal chemistry.

Hypoxia enhances gene expression of inducible nitric oxide synthase and matrix metalloproteinase‐9 in ras/myc‐transformed serum‐free mouse embryo cells under simulated inflammatory and infectious conditions

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2008, Cell biology international.

l-NAME inhibits tumor cell progression and pulmonary metastasis of r/m HM-SFME-1 cells by decreasing NO from tumor cells and TNF-α from macrophages

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2008, Molecular and Cellular Biochemistry.

Low-level bisphenol A increases production of glial fibrillary acidic protein in differentiating astrocyte progenitor cells through excessive STAT3 and Smad1 activation.

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2006, Toxicology.

Changes in the Amounts of the NAD-dependent Sorbitol Dehydrogenase and Its Involvement in the Development of Apple Fruit

Y. Kanayama, S. Yamaki, J. Soejima, 1996 .

Amino Acid Sequence of Oligopeptide Causes Marked Difference in DNA Compaction and Transcription.

K. Yoshikawa, K. Kubo, A. Zinchenko, 2019, Biophysical journal.

Two detection methods of genetically modified maize and the state of its import into Japan

H. Kamada, H. Yamaguchi, H. Umetsu, 2003 .

Homology modeling and structural analysis of human γ-glutamylcysteine ligase catalytic subunit for antitumor drug development

T. Akitaya, H. Yamaguchi, Y. Kidachi, 2012 .

Purification and Properties of NAD-Dependent Sorbitol Dehydrogenase from Apple Fruit

Y. Kanayama, S. Yamaki, H. Yamaguchi, 1994 .

Chemical composition of dried eyeballs from Euphausia superba and Euphausia pacifica

H. Yamaguchi, B. Yoshitomi, 2007, Fisheries Science.

Prediction of the possible inhibitory effect of 6- (methylsulfinyl)hexyl isothiocyanate (6MITC) and its analogs on P-glycoprotein (P-gp) by in silico analysis of their interaction energies

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2013 .

Structural insight into the ligand-receptor interaction between glycyrrhetinic acid (GA) and the high-mobility group protein B1 (HMGB1)-DNA complex

Hideaki Yamaguchi, Yumi Kidachi, Katsuyoshi Kamiie, 2012, Bioinformation.

Homology modeling and structural analysis of human N-acetyl-alpha-neuraminidase 3 (NEU3)

H. Yamaguchi, 2014 .

Utilization of 6-(methylsulfinyl)hexyl isothiocyanate for sensitization of tumor cells to antitumor agents in combination therapies.

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2013, Biochemical pharmacology.

Structural insight into the ligand-receptor interaction between 6-(methylsulfinyl)hexyl isothiocyanate and multidrug resistance-associated protein 1 nucleotide-binding domain 1

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2014 .

Homology modeling and structural analysis of 11β-hydroxysteroid dehydrogenase type 2.

K. Ryoyama, T. Akitaya, H. Yamaguchi, 2011, European journal of medicinal chemistry.

Selective cytotoxicity of glycyrrhetinic acid against tumorigenic r/m HM-SFME-1 cells: potential involvement of H-Ras downregulation.

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2010, Toxicology letters.

Differentiation of serum-free mouse embryo cells into an astrocytic lineage is associated with the asymmetric production of early neural, neuronal and glial markers.

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2008, Biological & pharmaceutical bulletin.

Selective toxicity of glycyrrhetinic acid against tumorigenic r/m HM-SFME-1 cells is potentially attributed to downregulation of glutathione.

K. Ryoyama, T. Akitaya, H. Yamaguchi, 2011, Biochimie.

Autoxidation of Docosahexaenoate with Different Chain Length of Alcohol

K. Fujimoto, Y. Endo, H. Yamaguchi, 2002 .

Anti-metastatic activity of an apple polyphenol crude fraction against human Ha ras-transformed metastatic mouse tumor (r/m HM-SFME-1) cells

K. Ryoyama, Yoshitaka Shimotai, I. Hatayama, 2004 .

Structural insight into the homology modeled human N-acetyl-alpha-neuraminidase 3 (NEU3)

H. Yamaguchi, 2014 .

Ligand-receptor Interaction between Triterpenoids and the 11β-Hydroxysteroid dehydrogenase type 2 (11βHSD2) Enzyme Predicts Their Toxic Effects against Tumorigenic r/m HM-SFME-1 Cells*

K. Ryoyama, Kenji Yoshida, T. Akitaya, 2011, The Journal of Biological Chemistry.

Augmented gene expression of quinone reductase by 6-(methylsulfinyl)hexyl isothiocyanate through avoiding its cytotoxicity.

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2003, Anticancer research.

Anti-nitric oxide production activity of isothiocyanates correlates with their polar surface area rather than their lipophilicity.

K. Ryoyama, H. Kiyota, H. Yamaguchi, 2009, European journal of medicinal chemistry.

The Augmenting Activity of 6-(Methylsulfinyl)hexyl Isothiocyanate on Cellular Glutathione Levels Is Less Sensitive to Thiol Compounds Than Its Cytotoxic Activity

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2009, Bioscience, biotechnology and biochemistry.

Structural basis for the interaction of 6-(methylsulfinyl) hexyl isothiocyanate with inducible nitric oxide synthase

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2014 .

Serum‐free mouse embryo cells generate a self‐sustaining feedback loop for an astrocyte marker protein and respond to cytokines and bisphenol A in accordance with the subtle difference in their differentiation state