Y. Kidachi

发表

Molecular docking and structural analysis of cofactor-protein interaction between NAD+ and 11β-hydroxysteroid dehydrogenase type 2

K. Ryoyama, T. Akitaya, H. Yamaguchi, 2012, Journal of Molecular Modeling.

Isolation of Ursolic Acid from Apple Peels and Its Specific Efficacy as a Potent Antitumor Agent

M. Hayashi, K. Ryoyama, K. Komiyama, 2008 .

Anti-Tumor Activity of an Enzymatically Synthesized α-1,6 Branched α-1,4-Glucan, Glycogen

H. Takata, K. Ryoyama, H. Yamaguchi, 2004 .

Mouse 11β-Hydroxysteroid Dehydrogenase Type 2 for Human Application: Homology Modeling, Structural Analysis and Ligand-Receptor Interaction

K. Ryoyama, T. Akitaya, H. Yamaguchi, 2011, Cancer informatics.

Intracellular accumulation of structurally varied isothiocyanates correlates with inhibition of nitric oxide production in proinflammatory stimuli-activated tumorigenic macrophage-like cells.

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2014, Bioorganic & medicinal chemistry.

6-(methylsulfinyl)hexyl isothiocyanate (6-MITC) from Wasabia japonica alleviates inflammatory bowel disease (IBD) by potential inhibition of glycogen synthase kinase 3 beta (GSK-3β).

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2021, European journal of medicinal chemistry.

Increased synthesis of GFAP by TCDD in differentiation-disrupted SFME cells.

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2003, Environmental toxicology and pharmacology.

Detection of 6-(methylsulfinyl)hexyl isothiocyanate (6-MITC) and its conjugate with N-acetyl-L-cysteine (NAC) by high performance liquid chromatograpy-atmospheric pressure chemical ionization mass spectrometry (HPLC-MS/APCI).

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2008, Chemical & pharmaceutical bulletin.

Toluene at Environmentally Relevant Low Levels Disrupts Differentiation of Astrocyte Precursor Cells

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2002, Archives of environmental health.

Interferon‐gamma and lipopolysaccharide stimulation increases matrix metalloproteinase‐9 expression and enhances invasion activity in ras/myc‐transformed serum‐free mouse embryo cells

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2007, Cell biology international.

Ras/myc-transformed serum-free mouse embryo cells under simulated inflammatory and infectious conditions increase levels of nitric oxide and matrix metalloproteinase-9 without a direct association between them

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2007, Molecular and Cellular Biochemistry.

Novel effects of glycyrrhetinic acid on the central nervous system tumorigenic progenitor cells: induction of actin disruption and tumor cell-selective toxicity.

K. Ryoyama, H. Yamaguchi, Tao Yu, 2010, European journal of medicinal chemistry.

Hypoxia enhances gene expression of inducible nitric oxide synthase and matrix metalloproteinase‐9 in ras/myc‐transformed serum‐free mouse embryo cells under simulated inflammatory and infectious conditions

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2008, Cell biology international.

l-NAME inhibits tumor cell progression and pulmonary metastasis of r/m HM-SFME-1 cells by decreasing NO from tumor cells and TNF-α from macrophages

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2008, Molecular and Cellular Biochemistry.

Low-level bisphenol A increases production of glial fibrillary acidic protein in differentiating astrocyte progenitor cells through excessive STAT3 and Smad1 activation.

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2006, Toxicology.

Larval mesenchyme cell specification in the primitive echinoid occurs independently of the double-negative gate

T. Minokawa, M. Yamaguchi, A. Yamazaki, 2014, Development.

DEV104331 1..11

T. Minokawa, M. Yamaguchi, A. Yamazaki, 2014 .

Homology modeling and structural analysis of human γ-glutamylcysteine ligase catalytic subunit for antitumor drug development

T. Akitaya, H. Yamaguchi, Y. Kidachi, 2012 .

“Micromere” formation and expression of endomesoderm regulatory genes during embryogenesis of the primitive echinoid Prionocidaris baculosa

T. Minokawa, A. Yamazaki, Y. Kidachi, 2012, Development, growth & differentiation.

Prediction of the possible inhibitory effect of 6- (methylsulfinyl)hexyl isothiocyanate (6MITC) and its analogs on P-glycoprotein (P-gp) by in silico analysis of their interaction energies

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2013 .

New Cytotoxic Phenolic Derivatives from Matured Fruits of Magnolia denudata

K. Ryoyama, H. Kiyota, T. Murayama, 2009, Bioscience, biotechnology, and biochemistry.

Structural insight into the ligand-receptor interaction between glycyrrhetinic acid (GA) and the high-mobility group protein B1 (HMGB1)-DNA complex

Hideaki Yamaguchi, Yumi Kidachi, Katsuyoshi Kamiie, 2012, Bioinformation.

Machilin G and Four Neolignans from Young Fruits of Magnolia denudata Show Various Degrees of Inhibitory Activity on Nitric Oxide (NO) Production

K. Ryoyama, S. Funayama, Y. Kidachi, 2008, Bioscience, biotechnology, and biochemistry.

Utilization of 6-(methylsulfinyl)hexyl isothiocyanate for sensitization of tumor cells to antitumor agents in combination therapies.

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2013, Biochemical pharmacology.

Structural insight into the ligand-receptor interaction between 6-(methylsulfinyl)hexyl isothiocyanate and multidrug resistance-associated protein 1 nucleotide-binding domain 1

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2014 .

Homology modeling and structural analysis of 11β-hydroxysteroid dehydrogenase type 2.

K. Ryoyama, T. Akitaya, H. Yamaguchi, 2011, European journal of medicinal chemistry.

Selective cytotoxicity of glycyrrhetinic acid against tumorigenic r/m HM-SFME-1 cells: potential involvement of H-Ras downregulation.

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2010, Toxicology letters.

Differentiation of serum-free mouse embryo cells into an astrocytic lineage is associated with the asymmetric production of early neural, neuronal and glial markers.

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2008, Biological & pharmaceutical bulletin.

Selective toxicity of glycyrrhetinic acid against tumorigenic r/m HM-SFME-1 cells is potentially attributed to downregulation of glutathione.

K. Ryoyama, T. Akitaya, H. Yamaguchi, 2011, Biochimie.

Anti-metastatic activity of an apple polyphenol crude fraction against human Ha ras-transformed metastatic mouse tumor (r/m HM-SFME-1) cells

K. Ryoyama, Yoshitaka Shimotai, I. Hatayama, 2004 .

Ligand-receptor Interaction between Triterpenoids and the 11β-Hydroxysteroid dehydrogenase type 2 (11βHSD2) Enzyme Predicts Their Toxic Effects against Tumorigenic r/m HM-SFME-1 Cells*

K. Ryoyama, Kenji Yoshida, T. Akitaya, 2011, The Journal of Biological Chemistry.

Augmented gene expression of quinone reductase by 6-(methylsulfinyl)hexyl isothiocyanate through avoiding its cytotoxicity.

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2003, Anticancer research.

Anti-nitric oxide production activity of isothiocyanates correlates with their polar surface area rather than their lipophilicity.

K. Ryoyama, H. Kiyota, H. Yamaguchi, 2009, European journal of medicinal chemistry.

The Augmenting Activity of 6-(Methylsulfinyl)hexyl Isothiocyanate on Cellular Glutathione Levels Is Less Sensitive to Thiol Compounds Than Its Cytotoxic Activity

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2009, Bioscience, biotechnology and biochemistry.

Structural basis for the interaction of 6-(methylsulfinyl) hexyl isothiocyanate with inducible nitric oxide synthase

K. Ryoyama, H. Yamaguchi, Y. Kidachi, 2014 .

Serum‐free mouse embryo cells generate a self‐sustaining feedback loop for an astrocyte marker protein and respond to cytokines and bisphenol A in accordance with the subtle difference in their differentiation state