L. Kirsch

发表

Polymorphic and Covalent Transformations of Gabapentin in Binary Excipient Mixtures after Milling-Induced Stress

K. Morris, S. Stamatis, Radaduen Tinmanee, 2018, Pharmaceutical Research.

Studies on the reactions between daptomycin and glyceraldehyde.

W. Kearney, L. Kirsch, W. Muangsiri, 2005, International journal of pharmaceutics.

Investigating Gabapentin Polymorphism Using Solid-State NMR Spectroscopy

R. Suryanarayanan, E. Munson, A. Kaushal, 2013, AAPS PharmSciTech.

The degradation pathways of glucagon in acidic solutions.

L. Kirsch, E. Rus, A. Joshi, 2000, International journal of pharmaceutics.

An Evaluation of a Fluorometric Method for Determining Binding Parameters of Drug–Carrier Complexes Using Mathematical Models Based on Total Drug Concentration

U. Nimmannit, L. Kirsch, W. Muangsiri, 2009, Journal of Fluorescence.

Pharmacokinetic prodrug modeling: in vitro and in vivo kinetics and mechanisms of ancitabine bioconversion to cytarabine.

R. Notari, L. Kirsch, 1984, Journal of pharmaceutical sciences.

The interaction mechanism between lipopeptide (daptomycin) and polyamidoamine (PAMAM) dendrimers

U. Nimmannit, Jiangyuan Qiu, L. Kirsch, 2015, Journal of peptide science : an official publication of the European Peptide Society.

The relative rates of glutamine and asparagine deamidation in glucagon fragment 22-29 under acidic conditions.

L. Kirsch, A. Joshi, 2002, Journal of pharmaceutical sciences.

Correlation of the Thermal Stability of Phospholipid‐Based Emulsions and the Microviscosity Measurements Using Fluorescence Polarization

L. Kirsch, Xiaoguang Zhang, Xiao-guang Zhang, 2004, Pharmaceutical development and technology.

Estimated pKa values for specific amino acid residues in daptomycin.

Liping Yu, Jiangyuan Qiu, L. Kirsch, 2011, Journal of pharmaceutical sciences.

The Ortho Effect on the Acidic and Alkaline Hydrolysis of Substituted Formanilides

L. Kirsch, Salil D. Desai, 2015 .

The role of aggregation and ionization in the chemical instability of Amphotericin B in aqueous methanol.

L. Kirsch, Phawanan Sawangchan, Éverton do Nascimento Alencar, 2023, International journal of pharmaceutics.

Preformulation Studies on the S-Isomer of Oxybutynin Hydrochloride, an Improved Chemical Entity (ICE™)

D. Wurster, P. Luner, S. Majuru, 2001, Drug development and industrial pharmacy.

Unveiling the Amphotericin B degradation pathway and its kinetics in lipid-based solutions.

E. Egito, É. N. Alencar, L. Kirsch, 2020, Journal of pharmaceutical sciences.

Development and validation of a high-performance liquid chromatography-mass spectroscopy assay for determination of artesunate and dihydroartemisinin in human plasma.

H. Naik, D. Murry, L. Kirsch, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A Novel Method for Assessing Drug Degradation Product Safety Using Physiologically-Based Pharmacokinetic Models and Stochastic Risk Assessment.

Hoa Q Nguyen, Stephen D Stamatis, Lee E Kirsch, 2015, Journal of pharmaceutical sciences.

The protein-binding and drug release properties of macromolecular conjugates containing daptomycin and dextran.

Lee E Kirsch, Walaisiri Muangsiri, L. Kirsch, 2006, International journal of pharmaceutics.

The kinetics of the alkaline degradation of daptomycin.

L. Kirsch, W. Muangsiri, 2001, Journal of pharmaceutical sciences.

Aqueous conversion kinetics and mechanisms of ancitabine, a prodrug of the antileukemic agent cytarabine.

R. Notari, L. Kirsch, 1984, Journal of pharmaceutical sciences.

Evaluation of lipopeptide (daptomycin) aggregation using fluorescence, light scattering, and nuclear magnetic resonance spectroscopy.

Jiangyuan Qiu, L. Kirsch, 2014, Journal of pharmaceutical sciences.

The Stabilizing Effect of Moisture on the Solid-State Degradation of Gabapentin

R. Suryanarayanan, E. Munson, L. Kirsch, 2011, AAPS PharmSciTech.

Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects

Beesan Tan, Lee E Kirsch, H. Naik, 2009, Malaria Journal.

Lessons unlearned.

L. Kirsch, 2004, PDA journal of pharmaceutical science and technology.

Studies on the instability of chlorhexidine, part I: kinetics and mechanisms.

L. Kirsch, Zhixin Zong, 2012, Journal of pharmaceutical sciences.

Characterization methods for the physical stability of biopharmaceuticals.

Lee E Kirsch, J. Wiencek, Lida T Nguyen, 2003, PDA journal of pharmaceutical science and technology.

Glycosylation of Aromatic Amines I: Characterization of Reaction Products and Kinetic Scheme

M. Gokhale, W. Kearney, L. Kirsch, 2009, AAPS PharmSciTech.

Excretion and tissue distribution of uniformly labeled 14 C-pentachlorophenol in rats.

J. E. Christian, L. Kirsch, S. M. Shaw, 1972, Journal of pharmaceutical sciences.

The physical stability of thermally-stressed phospholipid-based emulsions containing methyl, propyl and heptyl parabens as model drugs.

L. Kirsch, Xiao-guang Zhang, 2003, International journal of pharmaceutics.

Quantification of gabapentin polymorphs in gabapentin/excipient mixtures using solid state 13C NMR spectroscopy and X‐ray powder diffraction

K. Morris, S. Larsen, Radaduen Tinmanee, 2017, Journal of pharmaceutical and biomedical analysis.

Kinetic model for solid-state degradation of gabapentin.

Jiangyuan Qiu, Radaduen Tinmanee, L. Kirsch, 2012, Journal of pharmaceutical sciences.

An assessment of techniques for evaluating the physical stability of parenteral emulsions.

L. Kirsch, Xiao-guang Zhang, 2003, PDA journal of pharmaceutical science and technology.

The estimation of glutaminyl deamidation and aspartyl cleavage rates in glucagon.

Lee E Kirsch, L. Kirsch, Anjali B Joshi, 2004, International journal of pharmaceutics.

Studies on the mechanism of aspartic acid cleavage and glutamine deamidation in the acidic degradation of glucagon.

M. Sawai, W. Kearney, L. Kirsch, 2005, Journal of pharmaceutical sciences.

Investigating Gabapentin Polymorphism Using Solid-State NMR Spectroscopy

R. Suryanarayanan, E. Munson, L. Kirsch, 2013, AAPS PharmSciTech.

The effect of polyvinylpyrrolidine on the stability of taurolidine.

L. Kirsch, Y. Sihn, 1997, Pharmaceutical development and technology.

Quantitation of taurolidine decomposition in polymer solutions by chromotropic acid formaldehyde assay method.

J. Guillory, L. Kirsch, Y. Sihn, 1997, Journal of pharmaceutical and biomedical analysis.

Pharmaceutical container/closure integrity. III: Validation of the helium leak rate method for rigid pharmaceutical containers.

L. Kirsch, R. Gerth, L. Nguyen, 1997, PDA journal of pharmaceutical science and technology.

Package Integrity Testing

L. Kirsch, 2006 .

Pharmaceutical container/closure integrity. IV: Development of an indirect correlation between vacuum decay leak measurement and microbial ingress.

R. Schiere, L. Kirsch, W. Muangsiri, 1999, PDA journal of pharmaceutical science and technology.

Pharmaceutical container/closure integrity. II: The relationship between microbial ingress and helium leak rates in rubber-stoppered glass vials.

L. Kirsch, C. Moeckly, R. Gerth, 1997, PDA journal of pharmaceutical science and technology.

Pharmaceutical container/closure integrity. I: Mass spectrometry-based helium leak rate detection for rubber-stoppered glass vials.

L. Kirsch, C. Moeckly, L. Nguyen, 1997, PDA journal of pharmaceutical science and technology.

Glycosylation of aromatic amines III: Mechanistic implications of the pH-dependent glycosylation of various aromatic amines (kynurenine, 2'-aminoacetophenone, daptomycin, and sulfamethoxzaole).

M. Gokhale, L. Kirsch, 2009, Journal of pharmaceutical sciences.

Glycosylation of aromatic amines II: Kinetics and mechanisms of the hydrolytic reaction between kynurenine and glucose.

M. Gokhale, L. Kirsch, 2009, Journal of pharmaceutical sciences.

Particle Size Distribution Equivalency as Novel Predictors for Bioequivalence

S. Stamatis, L. Kirsch, Pratak Ngeacharernkul, 2018, AAPS PharmSciTech.

Characterization of seed nuclei in glucagon aggregation using light scattering methods and field-flow fractionation

J. Wiencek, L. Kirsch, Cindy C Hoppe, 2008, Journal of biological engineering.

Erratum to: The Stabilizing Effect of Moisture on the Solid-State Degradation of Gabapentin

R. Suryanarayanan, E. Munson, L. Kirsch, 2011, AAPS PharmSciTech.

Development of a Lyophilized Formulation for (R,R)-Formoterol (L)-Tartrate

D. Wurster, P. Luner, L. Kirsch, 2001, Drug Development and Industrial Pharmacy.

Bayesian hierarchical modeling of gabapentin absorption and disposition with application to dosing regimen assessment

Gintaras V. Reklaitis, Linas Mockus, Lee E. Kirsch, 2018 .

Particle Size Distribution Equivalency as Novel Predictors for Bioequivalence

S. Stamatis, L. Kirsch, Pratak Ngeacharernkul, 2018, AAPS PharmSciTech.