Shuiyu Lu

发表

The chemistry of labeling heterocycles with carbon-11 or fluorine-18 for biomedical imaging

V. Pike, Lisheng Cai, F. Siméon, 2020 .

Evaluation of [11C]S14506 and [18F]S14506 in rat and monkey as agonist PET radioligands for brain 5-HT1A receptors

S. Zoghbi, J. Liow, V. Pike, 2010 .

Alternative methods for labeling the 5-HT1A receptor agonist, 1-[2-(4-fluorobenzoylamino)ethyl]-4-(7-methoxynaphthyl)piperazine (S14506), with carbon-11 or fluorine-18

H. Wikström, V. Pike, Jinsoo Hong, 2005 .

Cu(I)-catalyzed (11)C carboxylation of boronic acid esters: a rapid and convenient entry to (11)C-labeled carboxylic acids, esters, and amides.

V. Pike, F. Aigbirhio, P. Riss, 2012, Angewandte Chemie.

Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT1B receptors.

C. Halldin, S. Zoghbi, J. Liow, 2019, Nuclear medicine and biology.

Synthesis of NCA [carbonyl‐11C]amides by direct reaction of in situ generated [11C]carboxymagnesium halides with amines under microwave‐enhanced conditions

V. Pike, Jinsoo Hong, Shuiyu Lu, 2003 .

Integration of a microwave reactor with synthia to provide a fully automated radiofluorination module

Victor W. Pike, John L. Musachio, Shuiyu Lu, 2007 .

Enhanced Nucleophilic Fluorination and Radiofluorination of Organosilanes Appended with Potassium-Chelating Leaving Groups.

V. Pike, Salvatore D. Lepore, Shuiyu Lu, 2014, Journal of fluorine chemistry.

Radiosynthesis and evaluation of an (18)F-labeled positron emission tomography (PET) radioligand for brain histamine subtype-3 receptors based on a nonimidazole 2-aminoethylbenzofuran chemotype.

Kimberly J. Jenko, S. Zoghbi, J. Liow, 2012, Journal of medicinal chemistry.

Rapid and Efficient Radiosyntheses of Meta-substituted [F]Fluoroarenes from [F]Fluoride Ion and Diaryliodonium Tosylates within a Microreactor.

V. Pike, Shuiyu Lu, Joong-Hyun Chun, 2011, European journal of organic chemistry.

Hypervalent Iodine Compounds as Precursors for Biomedical Radiotracers

V. Pike, F. Siméon, Shuiyu Lu, 2018, PATAI'S Chemistry of Functional Groups.

Radiofluorination of diaryliodonium tosylates under aqueous-organic and cryptand-free conditions.

V. Pike, Shuiyu Lu, S. Telu, 2013, Organic & biomolecular chemistry.

Pd(0)-Mediated 11C-Carbonylation of Aryl(mesityl)iodonium Salts as a Route to [11C]Arylcarboxylic Acids and Derivatives.

V. Pike, Shuiyu Lu, S. Telu, 2017, The Journal of organic chemistry.

11C-Labeling of Aryl Ketones as Candidate Histamine Subtype-3 Receptor PET Radioligands through Pd(0)-Mediated 11C-Carbonylative Coupling

V. Pike, W. Culligan, F. Siméon, 2017, Molecules.

An Investigation of (Diacetoxyiodo)arenes as Precursors for Preparing No-Carrier-Added [(18)F]Fluoroarenes from Cyclotron-Produced [(18)F]Fluoride Ion.

Mohammad B. Haskali, V. Pike, C. Morse, 2016, The Journal of organic chemistry.

[O-methyl-11C]N-(4-(4-(3-Chloro-2-methoxyphenyl)-piperazin-1-yl)butyl)-1H-indole-2-carboxamide ([11C]BAK4-51) Is an Efflux Transporter Substrate and Ineffective for PET Imaging of Brain D3 Receptors in Rodents and Monkey

S. Zoghbi, J. Liow, R. Gladding, 2018, Molecules.

Exploration of the labeling of [11C]tubastatin A at the hydroxamic acid site with [11C]carbon monoxide.

V. Pike, A. Kozikowski, Lisheng Cai, 2016, Journal of labelled compounds & radiopharmaceuticals.

[Carboxyl‐11C]Labelling of Four High‐Affinity cPLA2α Inhibitors and Their Evaluation as Radioligands in Mice by Positron Emission Tomography

S. Zoghbi, J. Liow, V. Pike, 2018, ChemMedChem.

Quinuclidine and DABCO Enhance the Radiofluorinations of 5-Substituted 2-Halopyridines.

V. Pike, Lisheng Cai, Shuiyu Lu, 2017, European journal of organic chemistry.

11 C-Labeling of Aryl Ketones as Candidate Histamine Subtype-3 Receptor PET Radioligands through Pd ( 0 )-Mediated 11 C-Carbonylative Coupling

V. Pike, W. Culligan, Shuiyu Lu, 2017 .

Radiosynthesis of [11C]Carboxamides via Reaction of [11C]CO2 Captured by a Cu(I)‐Based Catalyst System with Boronic Acid Ester Precursors

V. Pike, F. Aigbirhio, P. Riss, 2015 .

[ 11 C]Carbonyl Difluoride—a New and Highly Efficient [ 11 C]Carbonyl Group Transfer Agent

V. Pike, Shuiyu Lu, S. Telu, 2020, Angewandte Chemie.

[¹¹C]Carbonyl difluoride - a new and highly efficient [¹¹C]carbonyl group transfer agent.

V. Pike, Shuiyu Lu, S. Telu, 2020, Angewandte Chemie.

Separation of [18F]fluoride ion from proton‐irradiated [18O]water within an EOF‐driven micro‐reactor powered by the Capilix Capella™ platform

V. Pike, P. Watts, A. Prak, 2007 .

Evaluation of [C]S14506 and [F]S14506 in rat and monkey as agonist PET radioligands for brain 5-HT(1A) receptors.

S. Zoghbi, J. Liow, V. Pike, 2010, Current radiopharmaceuticals.

Chemistry with [18F]Fluoride Ion

Lisheng Cai, Victor W. Pike, Shuiyu Lu, 2008 .

Synthesis of [F]Xenon Difluoride as a Radiolabeling Reagent from [F]Fluoride Ion in a Micro-reactor and at Production Scale.

V. Pike, Shuiyu Lu, 2010, Journal of fluorine chemistry.

[carbonyl-C]Benzyl acetate: automated radiosynthesis via Pd-mediated [C]carbon monoxide chemistry and PET measurement of brain uptake in monkey.

V. Pike, R. Innis, M. Fujita, 2010, Journal of labelled compounds & radiopharmaceuticals.

Syntheses of mGluR5 PET radioligands through the radiofluorination of diaryliodonium tosylates.

V. Pike, F. Siméon, Shuiyu Lu, 2011, Organic & biomolecular chemistry.

Single-step high-yield radiosynthesis and evaluation of a sensitive 18F-labeled ligand for imaging brain peripheral benzodiazepine receptors with PET.

Shuiyu Lu, Sami S Zoghbi, Victor W Pike, 2009, Journal of medicinal chemistry.

Fast and high-yield microreactor syntheses of ortho-substituted [(18)F]fluoroarenes from reactions of [(18)F]fluoride ion with diaryliodonium salts.

Shuiyu Lu, Victor W Pike, V. Pike, 2010, The Journal of organic chemistry.

[¹¹C]Rhodamine-123: synthesis and biodistribution in rodents.

S. Zoghbi, J. Liow, V. Pike, 2012, Nuclear medicine and biology.

Effect of a P‐glycoprotein inhibitor, cyclosporin A, on the disposition in rodent brain and blood of the 5‐HT1A receptor radioligand, [11C](R)‐(––)‐RWAY

Jeih-San Liow, Shuiyu Lu, Sami S Zoghbi, 2007, Synapse.

The Inhibitor Ko143 Is Not Specific for ABCG2

M. Gottesman, J. Mulder, M. Hall, 2015, The Journal of Pharmacology and Experimental Therapeutics.

The Inhibitor Ko 143 Is Not Specific for ABCG 2

M. Gottesman, J. Mulder, M. Hall, 2015 .

PET ligands [18F]LSN3316612 and [11C]LSN3316612 quantify O-linked-β-N-acetyl-glucosamine hydrolase in the brain

S. Zoghbi, J. Liow, R. Gladding, 2020, Science Translational Medicine.

11C-CUMI-101, a PET Radioligand, Behaves as a Serotonin 1A Receptor Antagonist and Also Binds to α1 Adrenoceptors in Brain

Jeih-San Liow, Shuiyu Lu, Per Svenningsson, 2014, The Journal of Nuclear Medicine.

Selectivity in rodents and monkeys of 11C-CUMI-101, an agonist radioligand for serotonin 5-HT1A receptors

R. Parsey, J. Hirvonen, S. Zoghbi, 2010 .

D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: A PET study in a receptor internalization-deficient mouse model

Jeih-San Liow, Robert B. Innis, Victor W. Pike, 2010, NeuroImage.

Broad Scope and High-yield Access to Unsymmetrical Acyclic [11C]ureas for Biomedical Imaging from [11C]carbonyl Difluoride.

V. Pike, Shuiyu Lu, S. Telu, 2021, Chemistry.

An Empirical Quantitative Structure-Activity Relationship Equation Assists the Discovery of High-Affinity Phosphodiesterase 4D Inhibitors as Leads to PET Radioligands.

V. Pike, Shuiyu Lu, S. Telu, 2023, Journal of medicinal chemistry.

Syntheses of 11C- and 18F-labeled carboxylic esters within a hydrodynamically-driven micro-reactor.

Paul Watts, Frederick T Chin, Victor W Pike, 2004, Lab on a chip.

Synthesis of [F]fallypride in a micro-reactor: rapid optimization and multiple-production in small doses for micro-PET studies.

Shuiyu Lu, Victor W Pike, V. Pike, 2009, Current radiopharmaceuticals.

Crown Ether Nucleophilic Catalysts (CENCs): Agents for Enhanced Silicon Radiofluorination.

V. Pike, B. Yang, Salvatore D. Lepore, 2017, Journal of Organic Chemistry.

Nucleophile assisting leaving groups: a strategy for aliphatic 18F-fluorination.

V. Pike, Salvatore D. Lepore, Deboprosad Mondal, 2009, The Journal of organic chemistry.

Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT1B receptors.

C. Halldin, S. Zoghbi, J. Liow, 2019, Nuclear Medicine and Biology.

[carbonyl-11C]4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([11C]FIMX) is an effective radioligand for PET imaging of metabotropic glutamate receptor 1 (mGluR1) in monkey brain.

Kimberly J. Jenko, S. Zoghbi, J. Liow, 2015, Nuclear medicine and biology.

Gas Phase Transformations in Carbon-11 Chemistry

Shuiyu Lu, Sanjay Telu, Victor W Pike, 2024, International journal of molecular sciences.