T. Samad

发表

Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase.

Timothy L. Foley, K. Fennell, J. Pandit, 2017, Journal of medicinal chemistry.

Depression-like phenotype following chronic CB1 receptor antagonism

C. Beyer, J. Dwyer, B. Platt, 2010, Neurobiology of Disease.

Inhibition of monoacylglycerol lipase terminates diazepam‐resistant status epilepticus in mice and its effects are potentiated by a ketogenic diet

A. Vezzani, L. Porcu, G. Terrone, 2018, Epilepsia.

Localization and action of Dragon (repulsive guidance molecule b), a novel bone morphogenetic protein coreceptor, throughout the reproductive axis.

C. Woolf, Herbert Y. Lin, A. Mukherjee, 2005, Endocrinology.

COX2 in CNS neural cells mediates mechanical inflammatory pain hypersensitivity in mice.

C. Saper, G. FitzGerald, C. Woolf, 2009, The Journal of clinical investigation.

Acetylator phenotype in Iraqi patients with systemic lupus erythematosus.

R. A. Najim, T. Samad, Y. Y. Farid, 2005, Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit.

Free Water in White Matter Differentiates MCI and AD From Control Subjects

Felix C. Morency, M. Descoteaux, Pierre-Marc Jodoin, 2019, bioRxiv.

Free Water in White Matter Differentiates MCI and AD From Control Subjects

Felix C. Morency, M. Descoteaux, Pierre-Marc Jodoin, 2019, Frontiers in aging neuroscience.

Prostanoids and pain: unraveling mechanisms and revealing therapeutic targets.

C. Woolf, A. Sapirstein, T. Samad, 2002, Trends in molecular medicine.

Cyclooxygenase-2 and antagonists in pain management

S. Abdi, T. Samad, 2001, Current opinion in anaesthesiology.

Hemojuvelin Acts as a Bone Morphogenetic Protein Co-Receptor To Regulate Hepcidin Expression.

N. Andrews, R. Chung, C. Woolf, 2005 .

Dragon (Repulsive Guidance Molecule b) Inhibits IL-6 Expression in Macrophages

S. Arber, R. Weissleder, Rishard Salie, 2011, The Journal of Immunology.

Dragon enhances BMP signaling and increases transepithelial resistance in kidney epithelial cells.

Dennis Brown, C. Hong, R. Bouley, 2010, Journal of the American Society of Nephrology : JASN.

Inhibits IL-6 Expression in Macrophages Dragon (Repulsive Guidance Molecule b)

S. Arber, R. Weissleder, Rishard Salie, 2010 .

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

Raymond T Chung, Yin Xia, N. Andrews, 2006, Nature Genetics.

Methodes et compositions pour reguler le metabolisme du fer

R. Chung, Herbert Y. Lin, Jodie L Babitt, 2006 .

Sustained reduction of serum neurofilament light chain over 7 years by alemtuzumab in early relapsing–remitting MS

M. Sormani, L. Kappos, P. Benkert, 2021, Multiple sclerosis.

Target occupancy study and whole-body dosimetry with a MAGL PET ligand [11C]PF-06809247 in non-human primates

R. Carson, C. Halldin, A. Takano, 2021, EJNMMI Research.

The cPLA2α inhibitor efipladib decreases nociceptive responses without affecting PGE2 levels in the cerebral spinal fluid

J. D. Clark, J. McKew, W. Duan, 2011, Neuropharmacology.

Identification and development of an irreversible monoacylglycerol lipase (MAGL) positron emission tomography (PET) radioligand with high specificity.

C. Halldin, A. Takano, Patrick E. Trapa, 2019, Journal of medicinal chemistry.

Cytosolic phospholipase A 2 (cid:1) regulates induction of brain cyclooxygenase-2 in a mouse model of inﬂammation

J. Bonventre, A. Sapirstein, H. Saito, 2005 .

Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation.

Timothy L. Foley, J. Pandit, J. Cianfrogna, 2018, Journal of medicinal chemistry.

High basal expression and injury-induced down regulation of two regulator of G-protein signaling transcripts, RGS3 and RGS4 in primary sensory neurons

C. Woolf, M. Costigan, S. Tate, 2003, Molecular and Cellular Neuroscience.

Regulation of dopaminergic pathways by retinoids: activation of the D2 receptor promoter by members of the retinoic acid receptor-retinoid X receptor family.

P. Chambon, E. Borrelli, W. Krężel, 1997, Proceedings of the National Academy of Sciences of the United States of America.

p38 MAPK Activation by NGF in Primary Sensory Neurons after Inflammation Increases TRPV1 Levels and Maintains Heat Hyperalgesia

C. Woolf, R. Ji, Shan-xue Jin, 2002, Neuron.

Voltage-gated sodium channels in pain states: Role in pathophysiology and targets for treatment

Michael F. Jarvis, Sulayman D. Dib-Hajj, Katharina Zimmermann, 2009, Brain Research Reviews.

Prostaglandin E2 Receptor EP4 Contributes to Inflammatory Pain Hypersensitivity

C. Woolf, L. Barrett, F. Amaya, 2006, Journal of Pharmacology and Experimental Therapeutics.

Impaired locomotion and dopamine signaling in retinoid receptor mutant mice.

P Chambon, P. Chambon, E. Borrelli, 1998, Science.

Interleukin-1β-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity

Adam Sapirstein, Clifford J. Woolf, Joseph V. Bonventre, 2001, Nature.

Passive immunotherapy targeting amyloid-β reduces cerebral amyloid angiopathy and improves vascular reactivity.

J. Cirrito, G. Zipfel, K. Bales, 2016, Brain : a journal of neurology.

Dynamic Changes in the MicroRNA Expression Profile Reveal Multiple Regulatory Mechanisms in the Spinal Nerve Ligation Model of Neuropathic Pain

Wei Liu, Yizheng Li, Seena K. Ajit, 2011, PloS one.

Absence of opiate rewarding effects in mice lacking dopamine D2 receptors

E. Borrelli, B. Roques, O. Valverde, 1997, Nature.

Nociceptors Are Interleukin-1β Sensors

Alexander M Binshtok, Katharina Zimmermann, B. Bean, 2008, The Journal of Neuroscience.

DRAGON, a Bone Morphogenetic Protein Co-receptor*

A. Brivanlou, C. Woolf, L. Attisano, 2005, Journal of Biological Chemistry.

JPET # 105569 1 Prostaglandin E 2 receptor EP 4 contributes to inflammatory pain hypersensitivity

C. Woolf, L. Barrett, F. Amaya, 2006 .

The molecular basis of pain and its clinical implications in rheumatology

Seena K. Ajit, D. Blake, B. Bingham, 2009, Nature Clinical Practice Rheumatology.

Diversity of Expression of the Sensory Neuron-Specific TTX-Resistant Voltage-Gated Sodium Ion Channels SNS and SNS2

C. Woolf, M. Costigan, I. Decosterd, 2000, Molecular and Cellular Neuroscience.

DRAGON: A Member of the Repulsive Guidance Molecule-Related Family of Neuronal- and Muscle-Expressed Membrane Proteins Is Regulated by DRG11 and Has Neuronal Adhesive Properties

C. Woolf, A. Srinivasan, R. Ji, 2004, The Journal of Neuroscience.

The BMP Coreceptor RGMb Promotes While the Endogenous BMP Antagonist Noggin Reduces Neurite Outgrowth and Peripheral Nerve Regeneration by Modulating BMP Signaling

S. Arber, G. Coppola, Rishard Salie, 2011, The Journal of Neuroscience.

Repulsive Guidance Molecule (RGMa), a DRAGON Homologue, Is a Bone Morphogenetic Protein Co-receptor*

C. Woolf, Herbert Y. Lin, Jodie L Babitt, 2005, Journal of Biological Chemistry.

Absence of dopamine D2 receptors unmasks an inhibitory control over the brain circuitries activated by cocaine

H. Meziane, A. Usiello, E. Borrelli, 2007, Proceedings of the National Academy of Sciences.

Loss of Retrograde Endocannabinoid Signaling and Reduced Adult Neurogenesis in Diacylglycerol Lipase Knock-out Mice

M. Pangalos, Gareth Williams, F. Walsh, 2010, The Journal of Neuroscience.

Cytosolic phospholipase A2alpha regulates induction of brain cyclooxygenase-2 in a mouse model of inflammation.

J. Bonventre, A. Sapirstein, H. Saito, 2005, American Journal of Physiology. Regulatory Integrative and Comparative Physiology.

Cyclooxygenase 2 expression in the spared nerve injury model of neuropathic pain

C. Woolf, G. Geisslinger, T. Kohno, 2004, Neuroscience.

A dysregulated endocannabinoid-eicosanoid network supports pathogenesis in a mouse model of Alzheimer's disease.

D. Nomura, J. Duerr, J. Schwartz, 2012, Cell reports.

Genome-wide association study identifies multiple novel loci associated with disease progression in subjects with mild cognitive impairment

H. Soares, E. Katz, P. Aisen, 2011, Translational Psychiatry.

Localization and action of Dragon (RGMb), a novel BMP co-receptor, throughout the reproductive axis.

Herbert Y. Lin, A. Mukherjee, G. Brenner, 2007 .

Genetic and Functional Analysis of Human P2X5 Reveals a Distinct Pattern of Exon 10 Polymorphism with Predominant Expression of the Nonfunctional Receptor Isoform

P. Chanda, Yuchen Bai, D. Vasilyev, 2010, Molecular Pharmacology.

Simultaneous determination of 2-arachidonoylglycerol, 1-arachidonoylglycerol and arachidonic acid in mouse brain tissue using liquid chromatography/tandem mass spectrometry.

P. Chanda, Mei-Yi Zhang, Ying Gao, 2010, Journal of mass spectrometry : JMS.

Monoacylglycerol Lipase Activity Is a Critical Modulator of the Tone and Integrity of the Endocannabinoid System

M. Pangalos, P. Chanda, David S. Garbe, 2010, Molecular Pharmacology.

Inhibition of 2-AG hydrolysis differentially regulates blood brain barrier permeability after injury

H. Xi, J. Quan, R. Bell, 2018, Journal of Neuroinflammation.

Multiplex proteomics identifies novel CSF and plasma biomarkers of early Alzheimer’s disease

O. Hansson, N. Mattsson, C. Whelan, 2019, Acta Neuropathologica Communications.

Transport and Localization of the DEG/ENaC Ion Channel BNaC1α to Peripheral Mechanosensory Terminals of Dorsal Root Ganglia Neurons

D. Corey, C. Woolf, Ljiljana Žuvela-Jelaska, 2001, The Journal of Neuroscience.

Control of lactotrop proliferation by dopamine: Essential role of signaling through D2 receptors and ERKs

E. Borrelli, R. Picetti, C. Iaccarino, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of 2-AG hydrolysis differentially regulates blood brain barrier permeability after injury

H. Xi, R. Bell, T. Lanz, 2018, Journal of Neuroinflammation.

Signaling by dopamine regulates D2 receptors trafficking at the membrane

E. Borrelli, R. Picetti, V. Fontaine, 2008, Cell cycle.

Abstracts of the 6th Meeting of the Neapolitan Brain Group

Martine, Arianna, G. Fiorito, 2018, BMC Neuroscience.

Periganglionic inflammation elicits a distally radiating pain hypersensitivity by promoting COX-2 induction in the dorsal root ganglion

C. Woolf, L. Barrett, F. Amaya, 2009, Pain.

A Modest Increase in 11C-PK11195-Positron Emission Tomography TSPO Binding in Depression Is Not Associated With Serum C-Reactive Protein or Body Mass Index

Karen H. Adams, E. Bullmore, F. Turkheimer, 2021, Biological psychiatry. Cognitive neuroscience and neuroimaging.

TRPV1 signaling: mechanistic understanding and therapeutic potential.

N. Dekker, Lin-Hua Jiang, T. Samad, 2011, Current topics in medicinal chemistry.

Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease

Karen H. Adams, E. Bullmore, F. Turkheimer, 2023, Journal of Neuroinflammation.