Jung-Yaw Lin

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Abrin Triggers Cell Death by Inactivating a Thiol-specific Antioxidant Protein*

C. Hung, S. Shih, Yu-Hauh Wu, 2001, The Journal of Biological Chemistry.

Chimeric polypeptide of thymidine kinase and thymidylate kinase of shrimp white spot syndrome virus: thymidine kinase activity of the recombinant protein expressed in a baculovirus/insect cell system.

C. Lo, G. Kou, Chung-Hsiung Wang, 2002, Virology.

Targeting Ubiquitin Proteasome Pathway with Traditional Chinese Medicine for Treatment of Spinocerebellar Ataxia Type 3.

Yih-Ru Wu, M. Cheng, C. Chen, 2019, The American journal of Chinese medicine.

Aqueous extract of Gardenia jasminoides targeting oxidative stress to reduce polyQ aggregation in cell models of spinocerebellar ataxia 3

Yih-Ru Wu, Kuo-Hsuan Chang, C. Chen, 2014, Neuropharmacology.

Roles of mammalian structural units, ligand cluster and polyvalency in the Abrus precatorius agglutinin and glycoprotein recognition process.

A. M. Wu, L. Chow, Jung-Yaw Lin, 2009, Molecular immunology.

Structure and Magnetoresistance of Pr0.7(Sr0.3-yCay) MnO3

Ru‐Shi Liu, C. Huang, Ching-Jui Chang, 1998 .

The in vitro inhibitory effects of crude extracts of traditional Chinese herbs on 3-hydroxy-3-methylglutaryl-coenzyme A reductase on Vero cells.

Yi‐Jen Chen, F. Hsu, P. Chan, 2002, The American journal of Chinese medicine.

Large-Scale Sequencing Analysis of the Full-Length cDNA Library of Human Hepatocellular Carcinoma

S. Sugano, Hong‐Jen Lee, Yi-Da Chung, 2003, Journal of Biomedical Science.

The coat protein of the RNA bacteriophage MS2

H. Fraenkel-conrat, Jung-Yaw Lin, C. Tsung, 1967 .

Puerariae Radix Prevents Anxiety and Cognitive Deficits in Mice Under Oligomeric Aβ-Induced Stress.

H. Hsieh-Li, Hei-Jen Huang, Jung-Yaw Lin, 2019, The American journal of Chinese medicine.

Antihypertensive effects of tannins isolated from traditional Chinese herbs as non-specific inhibitors of angiontensin converting enzyme.

B. Tomlinson, F. Hsu, J. Tsai, 2003, Life sciences.

Functional Domains of a Pore-forming Cardiotoxic Protein, Volvatoxin A2*

Jung-Yaw Lin, Yui-Ping Weng, Yasmin Lin, 2004, Journal of Biological Chemistry.

Abrin and Ricin: New Anti-tumour Substances

K. Tserng, T. Tung, Jung-Yaw Lin, 1970, Nature.

Treatment with a Ginkgo biloba extract, EGb 761, inhibits excitotoxicity in an animal model of spinocerebellar ataxia type 17

Chung-Hsin Wu, H. Hsieh-Li, G. Lee-Chen, 2016, Drug design, development and therapy.

Role of the CCAAT-Binding Protein NFY in SCA17 Pathogenesis

Chung-Hsin Wu, Guan-Chiun Lee, H. Hsieh-Li, 2012, PloS one.

Amino acid sequence of trichoanguina, a ribosomal-inactivating protein from Trichosanthes anguina seeds

A. Tsugita, Y. Ueno, M. Kamo, 1996 .

Cloning and expression of three abrin A‐chains and their mutants derived by site‐specific mutagenesisin Escherichia coli

C. Hung, Jung-Yaw Lin, Jeen-Kuan Chen, 1994 .

Inhibitory effects of nontoxic protein volvatoxin A1 on pore‐forming cardiotoxic protein volvatoxin A2 by interaction with amphipathic α‐helix

Su-Chang Lin, Y. Liaw, Jung-Yaw Lin, 2006, The FEBS journal.

Isolation of a New Cardiotoxic Protein from the Edible Mushroom, Volvariella volvacea

T. Jeng, G. Shi, T. Tung, 1973, Nature.

The aqueous extract of Glycyrrhiza inflata can upregulate unfolded protein response-mediated chaperones to reduce tau misfolding in cell models of Alzheimer’s disease

Yih-Ru Wu, Kuo-Hsuan Chang, C. Chen, 2016, Drug design, development and therapy.

A New Crystal Form of Abrin-a from the Seeds of

Y. Liaw, T. Haji, Jung-Yaw Lin, 1994 .

Aqueous extract of Glycyrrhiza inflata inhibits aggregation by upregulating PPARGC1A and NFE2L2-ARE pathways in cell models of spinocerebellar ataxia 3.

Yih-Ru Wu, M. Cheng, Hsiang-Yu Tang, 2014, Free radical biology & medicine.

Cardiotoxic protein from edible mushrooms

Hua-Lin Wu, T. Jeng, G. Shi, 1974, Nature.

Recognition intensities of submolecular structures, mammalian glyco-structural units, ligand cluster and polyvalency in abrin-a-carbohydrate interactions.

A. M. Wu, L. Chow, Jung-Yaw Lin, 2010, Biochimie.

The potential of lactulose and melibiose, two novel trehalase-indigestible and autophagy-inducing disaccharides, for polyQ-mediated neurodegenerative disease treatment.

Jinn-Moon Yang, Yih-Ru Wu, Guan-Chiun Lee, 2015, Neurotoxicology.

Preparation and anti-HIV activities of retrojusticidin B analogs and azalignans.

Shoei‐Sheng Lee, Jung-Yaw Lin, Chia-Chuan Chang, 2004, Bioorganic & medicinal chemistry.

Effects of a Chinese Herbal Medicine, Guan-Jen-Huang (Aeginetia indica Linn.), on Renal Cancer Cell Growth and Metastasis

Sai-Wen Tang, Yu-Huei Liu, Jung-Yaw Lin, 2011, Evidence-based complementary and alternative medicine : eCAM.

Involvement of Prohibitin Upregulation in Abrin-Triggered Apoptosis

K. Peck, Yu-Huei Liu, Jung-Yaw Lin, 2011, Evidence-based complementary and alternative medicine : eCAM.

A new fungal immunomodulatory protein, FIP-fve isolated from the edible mushroom, Flammulina velutipes and its complete amino acid sequence

J. Ko, C. Kao, R. Lin, 1995 .

Up-Regulation of Vascular Endothelial Growth Factor-D Expression in Clear Cell Renal Cell Carcinoma by CD74: A Critical Role in Cancer Cell Tumorigenesis1

Sai-Wen Tang, Wei-Chou Lin, Yu-Huei Liu, 2008, The Journal of Immunology.

The isolation and purification of pre-S2 containing hepatitis B virus surface antigen by chemical affinity chromatography

S. Chu, Y. Hsieh, Jung-Yaw Lin, 1987, Applied biochemistry and biotechnology.

Native and/or asialo‐Tamm‐Horsfall glycoproteins Sd(a+) are important receptors for Triticum vulgaris (wheat germ) agglutinin and for three toxic lectins (abrin‐a, ricin and mistletoe toxic lectin‐I)

A. M. Wu, J. Lin, Shuh-Chyung Song, 1995, FEBS letters.

Aqueous Extract of Paeonia suffruticosa Inhibits Migration and Metastasis of Renal Cell Carcinoma Cells via Suppressing VEGFR-3 Pathway

Sai-Wen Tang, Chung‐Chieh Wang, Shoei‐Sheng Lee, 2012, Evidence-based complementary and alternative medicine : eCAM.

Dimerization of the N-terminal Amphipathic α-Helix Domain of the Fungal Immunomodulatory Protein from Ganoderma tsugae (Fip-gts) Defined by a Yeast Two-hybrid System and Site-directed Mutagenesis*

J. Lin, C. Hung, Jung-Yaw Lin, 1997, The Journal of Biological Chemistry.

Fungal immunomodulatory protein from Flammulina velutipes induces interferon-gamma production through p38 mitogen-activated protein kinase signaling pathway.

P. Wang, J. Ko, Jung-Yaw Lin, 2004, Journal of agricultural and food chemistry.

Recent advances of cluster of differentiation 74 in cancer

Yu-Huei Liu, Jung-Yaw Lin, 2014 .

Up-Regulation of Vascular Endothelial Growth Factor-D Expression in Clear Cell Renal Cell Carcinoma by CD74: A Critical Role in Cancer Cell Tumorigenesis1

Sai-Wen Tang, Wei-Chou Lin, Yu-Huei Liu, 2008, The Journal of Immunology.

Ricin Triggers Apoptotic Morphological Changes through Caspase-3 Cleavage of BAT3*

S. Shih, Yu-Hauh Wu, Jung-Yaw Lin, 2004, Journal of Biological Chemistry.

TOXIC AND NONTOXIC LECTINS FROM ABRUS PRECATORIUS AND RICINUS COMMUNIS

T. Tung, Jung-Yaw Lin, L. Ting, 1978 .

Amino Acid Sequences of Trypsin Inhibitors from the Melon Cucumis melo

Jung-Yaw Lin, Chi‐Fang Lee, 2005 .

Inactivation of Acacia confusa trypsin inhibitor by site‐specific mutagenesis

C. Hung, Jung-Yaw Lin, Ming-Chih Lee, 1994, FEBS letters.

Identification of differentially expressed genes in clear cell renal cell carcinoma by analysis of full-length enriched cDNA library.

Sai-Wen Tang, Wei-Chou Lin, M. Lai, 2006, Journal of biomedical science.

Liver fatty acid-binding protein (L-FABP) promotes cellular angiogenesis and migration in hepatocellular carcinoma

Yu-Huei Liu, Jung-Yaw Lin, Shao-Chun Lu, 2016, Oncotarget.

Corosolic Acid Inhibits Hepatocellular Carcinoma Cell Migration by Targeting the VEGFR2/Src/FAK Pathway

Jung-Yaw Lin, Shao-Chun Lu, Hsuan-Yuan Lin, 2015, PloS one.

MYC pathway is activated in clear cell renal cell carcinoma and essential for proliferation of clear cell renal cell carcinoma cells.

Sai-Wen Tang, Wei-Chou Lin, M. Lai, 2009, Cancer letters.

Nicotinamide N-methyltransferase induces cellular invasion through activating matrix metalloproteinase-2 expression in clear cell renal cell carcinoma cells.

Sai-Wen Tang, Chung‐Chieh Wang, Wei-Chou Lin, 2011, Carcinogenesis.

Chinese Herbal Medicine Glycyrrhiza inflataReduces Aβ Aggregation and Exerts Neuroprotection through Anti-Oxidation and Anti-Inflammation.

Kuo-Hsuan Chang, C. Chen, G. Lee-Chen, 2018, The American journal of Chinese medicine.

Full-Length Enrich c-DNA Libraries-Clear Cell-Renal Cell Carcinoma

Sai-Wen Tang, Jung-Yaw Lin, 2012, Journal of oncology.

Gene expression analysis of human hepatocellular carcinoma by using full-length cDNA library.

S. Sugano, Yutaka Suzuki, H. Hsu, 2006, Journal of biomedical science.

Structural Insights into DD-Fold Assembly and Caspase-9 Activation by the Apaf-1 Apoptosome.

Y. Lo, Wen-Pin Kao, Jung-Yaw Lin, 2017, Structure.

Indole and synthetic derivative activate chaperone expression to reduce polyQ aggregation in SCA17 neuronal cell and slice culture models

Chung-Hsin Wu, H. Hsieh-Li, Kuo-Hsuan Chang, 2014, Drug design, development and therapy.

Protective Effects of Wogonin against Alzheimer's Disease by Inhibition of Amyloidogenic Pathway

Chung-Hsin Wu, Yu-Chen Yu, Jung-Yaw Lin, 2017, Evidence-based complementary and alternative medicine : eCAM.

Crystallization and preliminary X‐ray analysis of volvatoxin A2 from Volvariella volvacea

J. Lin, Y. Liaw, Jung-Yaw Lin, 1996, Proteins.

The in vitro Inhibitory Effect of Tannin Derivatives on 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase on Vero Cells

Yi‐Jen Chen, F. Hsu, P. Chan, 2001, Pharmacology.

Aqueous extracts of Paeonia suffruticosa modulates mitochondrial proteostasis by reactive oxygen species-induced endoplasmic reticulum stress in pancreatic cancer cells.

C. Hsieh, Chao-Jung Chen, Der-Yen Lee, 2018, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Aqueous extract of Polygonum bistorta modulates proteostasis by ROS-induced ER stress in human hepatoma cells

Chao-Jung Chen, Sai-Wen Tang, Chao-Jung Chen, 2017, Scientific Reports.

A biophysical elucidation for less toxicity of Agglutinin than Abrin-a from the Seeds of Abrus Precatorius in consequence of crystal structure

Jung-Yaw Lin, Jack Y. K. Cheng, T. Lu, 2010, Journal of Biomedical Science.

Growth suppression of human colorectal carcinoma in nude mice by monoclonal antibody C27-abrin A chain conjugate

Chung Lee, Z. Chang, Jung-Yaw Lin, 1995, Diseases of the colon and rectum.

Altered expression of HSPA5, HSPA8 and PARK7 in spinocerebellar ataxia type 17 identified by 2-dimensional fluorescence difference in gel electrophoresis.

Chung-Hsin Wu, Guan-Chiun Lee, H. Hsieh-Li, 2009, Clinica chimica acta; international journal of clinical chemistry.

The potential of synthetic indolylquinoline derivatives for Aβ aggregation reduction by chemical chaperone activity

Chung-Hsin Wu, H. Fung, Yi-Chun Chen, 2016, Neuropharmacology.

Yang-Dan-Tang, Identified from 15 Chinese Herbal Formulae, Inhibits Human Lung Cancer Cell Proliferation via Cell Cycle Arrest

H. Hsieh-Li, C. Shen, Jung-Yaw Lin, 2012, Evidence-based complementary and alternative medicine : eCAM.

Primary Structure and Function Analysis of the Abrus precatorius Agglutinin A Chain by Site-directed Mutagenesis

Su-Chang Lin, J. Lin, M. Hwang, 2000, Journal of Biological Chemistry.

The complete primary structure of abrin‐a B chain

A. Tsugita, Jung-Yaw Lin, Yung-Liang Chen, 1992, FEBS letters.

Ribonucleotide reductase of shrimp white spot syndrome virus (WSSV): expression and enzymatic activity in a baculovirus/insect cell system and WSSV-infected shrimp.

C. Lo, G. Kou, Yun-Shiang Chang, 2002, Virology.

Isolation of four isotoxic proteins and one agglutinin from jequiriti bean (Abrus precatorius).

S. Hu, J. Lin, T. C. Lee, 1981, Toxicon : official journal of the International Society on Toxinology.

Epicutaneous exposure of protein antigen induces a predominant Th2-like response with high IgE production in mice.

Li-Fang Wang, R. Lin, L. F. Wang, 1996, Journal of immunology.

The aqueous extract of Glycyrrhiza inflata can upregulate unfolded protein response-mediated chaperones to reduce tau misfolding in cell models of alzheimer’s disease

Yih-Ru Wu, Kuo-Hsuan Chang, C. Chen, 2016 .

Crystal structure of abrin-a at 2.14 A.

T. Tahirov, Y. Liaw, Y C Liaw, 1995, Journal of molecular biology.

Sechiumin, a ribosome-inactivating protein from the edible gourd, Sechium edule Swartz--purification, characterization, molecular cloning and expression.

L. Chow, Jung-Yaw Lin, Tsann-Huei Wu, 1998, European journal of biochemistry.