Benjamin Schmid

发表

Human Dopaminergic Neurons Lacking PINK1 Exhibit Disrupted Dopamine Metabolism Related to Vitamin B6 Co-Factors

R. Krüger, M. Ueffing, T. Gasser, 2020, iScience.

A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson’s disease

P. May, W. Wurst, R. Krüger, 2020, Science Translational Medicine.

Generation of a set of isogenic iPSC lines carrying all APOE genetic variants (Ɛ2/Ɛ3/Ɛ4) and knock-out for the study of APOE biology in health and disease.

A. Ramírez, O. Brüstle, A. Ebneth, 2021, Stem cell research.

BioZoom INDUCED PLURIPOTENT STEM CELLS ( IPSC ) FOR MODELING OF ALZHEIMER ’ S DISEASE

G. Waldemar, T. Nielsen, J. Nielsen, 2015 .

Generation of two gene edited iPSC-lines carrying a DOX-inducible NGN2 expression cassette with and without GFP in the AAVS1 locus.

U. Mau-Holzmann, A. Ebneth, Rachel Steeg, 2021, Stem cell research.

Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies.

Juan D. Pita-Almenar, P. Shih, A. Ebneth, 2021, Stem cell research.

Desmin Knock-Out Cardiomyopathy: A Heart on the Verge of Metabolic Crisis

U. Schlötzer-Schrehardt, T. Lücke, R. Schröder, 2022, International journal of molecular sciences.

Establishment of a human induced pluripotent stem cell neuronal model for identification of modulators of A53T α-synuclein levels and aggregation

R. Melki, Benjamin Schmid, B. Holst, 2021, PloS one.

Generation of an isogenic, gene-corrected iPSC line from a pre-symptomatic 28-year-old woman with an R406W mutation in the microtubule associated protein tau (MAPT) gene.

U. Mau-Holzmann, T. Nielsen, J. Nielsen, 2016, Stem cell research.

Generation of an isogenic, gene-corrected iPSC line from a symptomatic 59-year-old female patient with frontotemporal dementia caused by an R406W mutation in the microtubule associated protein tau (MAPT) gene.

U. Mau-Holzmann, T. Nielsen, J. Nielsen, 2016, Stem cell research.

Generation of a gene-corrected isogenic control hiPSC line derived from a familial Alzheimer's disease patient carrying a L150P mutation in presenilin 1.

T. Nielsen, J. Nielsen, K. Freude, 2016, Stem cell research.

Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1.

G. Waldemar, T. Nielsen, J. Nielsen, 2016, Stem cell research.

Astrocytic Reactivity Triggered by defective Mitophagy Activates NF-kB Signaling and Causes Neurotoxicity in Frontotemporal Dementia Type 3

Nadezhda T. Doncheva, J. Gorodkin, S. Cirera, 2021 .

The CST3 BB genotype and low cystatin C cerebrospinal fluid levels are associated with dementia in Lewy body disease.

D. Berg, T. Gasser, M. Synofzik, 2010, Journal of Alzheimer's disease : JAD.

59-year-old female patient with frontotemporal dementia caused by a R 406 W mutation in microtubule associated protein tau ( MAPT )

U. Mau-Holzmann, T. Nielsen, J. Nielsen, 2016 .

iPSC-derived neurons from GBA1-associated Parkinson’s disease patients show autophagic defects and impaired calcium homeostasis

S. Gygi, D. Berg, U. Hedrich, 2014, Nature Communications.

Derivation and Expansion Using Only Small Molecules of Human Neural Progenitors for Neurodegenerative Disease Modeling

Thomas Gasser, Cora S. Thiel, Peter Reinhardt, 2013, PloS one.

Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression.

Torsten Kluba, Daniela Berg, Thomas Gasser, 2013, Cell stem cell.

Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3

Nadezhda T. Doncheva, J. Gorodkin, S. Cirera, 2021, Stem cell reports.

Modeling neurodegenerative diseases with patient-derived induced pluripotent cells: Possibilities and challenges.

T. Nielsen, K. Freude, Yu Zhang, 2017, New biotechnology.

Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease

B. Klink, T. Gasser, J. Fitzgerald, 2018, PloS one.

Efficient processing of Alzheimer's disease amyloid-Beta peptides by neuroectodermally converted mesenchymal stem cells.

A. Ludolph, C. V. von Arnim, A. Storch, 2010, Stem cells and development.

Neprilysin activity in cerebrospinal fluid is associated with dementia and amyloid-β42 levels in Lewy body disease.

D. Berg, T. Gasser, C. Schulte, 2010, Journal of Alzheimer's disease : JAD.

Generation of two iPSC lines with either a heterozygous V717I or a heterozygous KM670/671NL mutation in the APP gene.

Ravi S Muddashetty, K. Freude, Benjamin Schmid, 2019, Stem cell research.

Lab resource: Stem cell lineGeneration of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1

G. Waldemar, T. Nielsen, J. Nielsen, 2016 .

Cardiac Findings in Amyotrophic Lateral Sclerosis: A Magnetic Resonance Imaging Study

W. Rottbauer, J. Kassubek, A. Ludolph, 2017, Front. Neurol..

Establishment and characterization of a human in vitro cell model for Parkinson 's Disease

Benjamin Schmid, 2013 .

Generation of two isogenic iPSC lines with either a heterozygous or a homozygous E280A mutation in the PSEN1 gene.

U. Mau-Holzmann, K. Freude, Benjamin Schmid, 2019, Stem cell research.

Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B

L. Bolund, Xin Liu, Fengping Xu, 2022 .

Correction: Derivation and Expansion Using Only Small Molecules of Human Neural Progenitors for Neurodegenerative Disease Modeling

H. Schöler, T. Gasser, C. Thiel, 2013, PLoS ONE.

Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line.

U. Mau-Holzmann, A. Ebneth, Ravi S Muddashetty, 2019, Stem cell research.

APOE4 Affects Basal and NMDAR-Mediated Protein Synthesis in Neurons by Perturbing Calcium Homeostasis

G. Gouras, S. Chakraborty, Ravi S Muddashetty, 2020, The Journal of Neuroscience.

Serum and Cerebrospinal Fluid Levels of Transthyretin in Lewy Body Disorders with and without Dementia

D. Berg, T. Gasser, C. Schulte, 2012, PloS one.

Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B

L. Bolund, Fengping Xu, Yonglun Luo, 2017, Stem cell reports.

Generation of induced pluripotent stem cells derived from a 77-year-old healthy woman as control for age related diseases.

T. Gasser, U. Mau-Holzmann, T. Kluba, 2016, Stem cell research.

Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific heterozygous mutation in CHMP2B.

T. Nielsen, J. Nielsen, K. Freude, 2016, Stem cell research.

Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H196.

T. Nielsen, J. Nielsen, P. Hyttel, 2016, Stem cell research.

Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H271.

T. Nielsen, J. Nielsen, P. Hyttel, 2016, Stem cell research.

Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H266.

T. Nielsen, J. Nielsen, P. Hyttel, 2016, Stem cell research.

Lab resource: Stem cell lineGeneration of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1

G. Waldemar, T. Nielsen, J. Nielsen, 2016 .

Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H196.

U. Mau-Holzmann, Alexander F Engelbrecht, T. Nielsen, 2016, Stem cell research.

Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H271.

U. Mau-Holzmann, Alexander F Engelbrecht, T. Nielsen, 2016, Stem cell research.

Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H266.

U. Mau-Holzmann, Alexander F Engelbrecht, T. Nielsen, 2016, Stem cell research.