D. McVicar

发表

LAB/NTAL/Lat2: a force to be reckoned with in all leukocytes?

Selinda J Orr, D. McVicar, 2011, Journal of leukocyte biology.

Killer Immunoglobulin Receptor 3 DL 1-mediated recognition of Human Leukocyte Antigen B

T. Beddoe, J. Rossjohn, S. Gras, 2017 .

Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B

T. Beddoe, J. Rossjohn, S. Gras, 2011, Nature.

Detection of KIR3DS1 on the Cell Surface of Peripheral Blood NK Cells Facilitates Identification of a Novel Null Allele and Assessment of KIR3DS1 Expression during HIV-1 Infection12

M. Altfeld, M. Carrington, J. Metcalf, 2007, The Journal of Immunology.

Understanding the tumour micro‐environment communication network from an NOS2/COX2 perspective

S. Lockett, D. Wink, S. Anderson, 2018, British journal of pharmacology.

Cutting Edge: Allele-Specific and Peptide-Dependent Interactions between KIR3DL1 and HLA-A and HLA-B12

M. Carrington, S. Rowland-Jones, P. Parham, 2007, The Journal of Immunology.

Novel KIR3DL1 Alleles and Their Expression Levels on NK Cells: Convergent Evolution of KIR3DL1 Phenotype Variation?12

M. Altfeld, M. Carrington, P. Parham, 2008, The Journal of Immunology.

Diversity and environmental adaptation of phagocytic cell metabolism

J. Weiss, L. Davies, D. McVicar, 2018, Journal of leukocyte biology.

Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2.

D. McVicar, L. Taylor, S. Paul, 2000, Blood.

proteasomal-mediated turnover CD33 responses are blocked by SOCS3 through accelerated

J. F. Burrows, J. Johnston, Joanne Elliott, 2013 .

CD33 responses are blocked by SOCS3 through accelerated proteasomal-mediated turnover.

J. F. Burrows, J. Johnston, Joanne Elliott, 2007, Blood.

Molecular Mechanisms of Nitric Oxide in Cancer Progression, Signal Transduction, and Metabolism.

D. Wink, S. Anderson, R. Cheng, 2019, Antioxidants & redox signaling.

Visualization and Identification of IL-7 Producing Cells in Reporter Mice

M. Ishii, R. Germain, N. Copeland, 2009, PloS one.

Mycobacterium tuberculosis Induces Irg1 in Murine Macrophages by a Pathway Involving Both TLR-2 and STING/IFNAR Signaling and Requiring Bacterial Phagocytosis

J. Weiss, A. Sher, R. Chari, 2022, Frontiers in Cellular and Infection Microbiology.

Myeloid-Derived Suppressive Cell Expansion Promotes Melanoma Growth and Autoimmunity by Inhibiting CD40/IL27 Regulation in Macrophages

K. Tsuneyama, G. Merlino, H. Young, 2021, Cancer Research.

Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase

A. Lane, R. Higashi, D. Wink, 2020, Nature Communications.

Aberrant DAP12 Signaling in the 129 Strain of Mice: Implications for the Analysis of Gene-Targeted Mice1

S. Anderson, A. Makrigiannis, J. Ortaldo, 2002, The Journal of Immunology.

Gene-Targeted Mice of Mice : Implications for the Analysis of Aberrant DAP 12 Signaling in the 129 Strain Anderson

S. Anderson, A. Makrigiannis, J. Ortaldo, 2002 .

Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID.

J. Johnston, O. Silvennoinen, M. Noguchi, 1994, Science.

Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors

J. Weiss, D. Wink, R. Cheng, 2018, The Journal of clinical investigation.

Characterization of an associated 16-kDa tyrosine phosphoprotein required for Ly-49D signal transduction.

S. Anderson, J. Ortaldo, P. Love, 1998, Journal of immunology.

Inhibition of thrombin-induced platelet aggregation using human single-chain Fv antibodies specific for TREM-like transcript-1

J. Mcmahon, Toshiyuki Mori, Barbara Giomarelli, 2006, Thrombosis and Haemostasis.

Corticosteroids inhibit the generation of lymphokine-activated killer activity in vitro

R. Merchant, H. Young, D. McVicar, 2004, Cancer Immunology, Immunotherapy.

Regulation of NK cells through the 80‐kDa TNFR (CD120b)

C. Ware, C. Smith, H. Young, 1995, Journal of leukocyte biology.

Thrombopoietin induces tyrosine phosphorylation and activation of the Janus kinase, JAK2.

J. Johnston, D. Longo, J. O’Shea, 1995, Blood.

Interaction of Ly-49D+ NK Cells with H-2Dd Target Cells Leads to Dap-12 Phosphorylation and IFN-γ Secretion1

J. Ortaldo, D. McVicar, J. Willette-Brown, 2000, The Journal of Immunology.

Intracellular Signaling by the Killer Immunoglobulin-Like Receptors and Ly49

D. Burshtyn, D. McVicar, 2001, Science's STKE.

Receptors Ly-49 D and Inhibitory Ly-49 G 2 NK Structure / Function Relationship of Activating McVicar

S. Anderson, R. Wange, J. Ortaldo, 1999 .

Cloning and characterization of a novel activating Ly49 closely related to Ly49A.

S. Anderson, A. Makrigiannis, J. Ortaldo, 1999, Journal of immunology.

Induction of DAP12 phosphorylation, calcium mobilization, and cytokine secretion by Ly49H

S. Anderson, J. Ortaldo, D. McVicar, 1999, Journal of leukocyte biology.

Structure/function relationship of activating Ly-49D and inhibitory Ly-49G2 NK receptors.

S. Anderson, R. Wange, J. Ortaldo, 1999, Journal of immunology.

A role for protein tyrosine kinase activity in natural cytotoxicity as well as antibody-dependent cellular cytotoxicity. Effects of herbimycin A.

J. O’Shea, D. Kuhns, J. Ortaldo, 1992, Journal of immunology.

Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phosphorylation.

J. O’Shea, M. Smyth, D. McVicar, 1992, Proceedings of the National Academy of Sciences of the United States of America.

T cell activation via the disialoganglioside GD3: analysis of signal transduction

D. Longo, M. Beckwith, J. Ortaldo, 1996, Journal of leukocyte biology.

HLA and Peptide Sensitivity Allotypic Dimorphism That Impacts Both KIR3DL1 Reveals a Lineage-Defining Mutational and Structural Analysis of

J. Rossjohn, E. Gostick, S. Anderson, 2014 .

The yin-yang of KIR3DL1/S1: molecular mechanisms and cellular function.

D. McVicar, G. O’Connor, Geraldine M. O’Connor, 2013, Critical reviews in immunology.

Lack of KIR3DS1 binding to MHC class I Bw4 tetramers in complex with CD8+ T cell epitopes.

M. Carrington, S. Rowland-Jones, T. Dong, 2007, AIDS research and human retroviruses.

Induction of T cell differentiation and lymphomagenesis in the thymus of mice with severe combined immune deficiency (SCID).

D. Longo, J. O’Shea, H. Young, 1994, Journal of immunology.

Common HIV-1 Peptide Variants Mediate Differential Binding of KIR3DL1 to HLA-Bw4 Molecules

M. Altfeld, M. Carrington, A. Piechocka-Trocha, 2011, Journal of Virology.

EpitopeMolecular Microarchitecture within the Bw4 Class I Molecules Is Dependent upon The Interaction of KIR3DL1*001 with HLA

T. Beddoe, J. Rossjohn, S. Gras, 2014 .

A human IL10 BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome

L. Feigenbaum, J. Bream, C. Hedrich, 2009, Proceedings of the National Academy of Sciences.

Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity.

D. Longo, T. Sayers, A. Brooks, 2015, Cancer research.

Intralesional infusion of lymphokine-activated killer (LAK) cells and recombinant interleukin-2 (rIL-2) for the treatment of patients with malignant brain tumor.

R. Merchant, H. Young, D. McVicar, 1988, Neurosurgery.

Implications for Gene Therapy-Limiting Expression of IL-2Rγc Delineate Differences in Signaling Thresholds Required for Lymphocyte Development and Maintenance

T. Chan, Selinda J Orr, D. McVicar, 2010, The Journal of Immunology.

Tec Family Kinases Modulate Thresholds for Thymocyte Development and Selection

J. Debnath, E. Schaeffer, P. Schwartzberg, 2000, The Journal of experimental medicine.

Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M 1-like Phenotype and Inhibits Tumor Metastasis Graphical

A. Guarini, W. Lamers, B. Ghesquière, 2018 .

Increased proliferation, cytotoxicity, and gene expression after stimulation of human peripheral blood T lymphocytes through a surface ganglioside (GD3)

D. Longo, A. Houghton, H. Young, 1994, Journal of immunology.

Environmental factors determine DAP12 deficiency to either enhance or suppress immunopathogenic processes

I. Gery, T. Takai, D. McVicar, 2013, Immunology.

Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes.

J. Johnston, J. O’Shea, B. Lal, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1

Amalio Telenti, Peter Parham, Stephen J O'Brien, 2007, Nature Genetics.

Analysis of Binding of KIR3DS1*014 to HLA Suggests Distinct Evolutionary History of KIR3DS1

M. Carrington, Rasmi Thomas, D. McVicar, 2011, The Journal of Immunology.

KIR3DS1Suggests Distinct Evolutionary History of Analysis of Binding of KIR3DS1*014 to HLA

Rasmi Thomas, M. Carrington, D. McVicar, 2011 .

Analysis of Binding of KIR 3 DS 1 * 014 to HLA Suggests Distinct Evolutionary History of KIR 3 DS 1

M. Carrington, Rasmi Thomas, D. McVicar, 2011 .

A BAC contig map of the Ly49 gene cluster in 129 mice reveals extensive differences in gene content relative to C57BL/6 mice.

S. Anderson, A. Makrigiannis, P. Schwartzberg, 2002, Genomics.

The Linker for Activation of B Cells (LAB)/Non-T Cell Activation Linker (NTAL) Regulates Triggering Receptor Expressed on Myeloid Cells (TREM)-2 Signaling and Macrophage Inflammatory Responses Independently of the Linker for Activation of T Cells*

Selinda J Orr, I. Francischetti, D. McVicar, 2009, The Journal of Biological Chemistry.

In contrast to HIV, KIR3DS1 does not influence outcome in HTLV-1 retroviral infection.

Aidan MacNamara, Nafisa-Katrin Seich al Basatena, B. Asquith, 2012, Human immunology.

Regulation of JAK3 expression and activation in human B cells and B cell malignancies.

J. Johnston, D. Longo, J. O’Shea, 1995, Journal of immunology.

NOS2 and COX2 Blockade Limits TNBC Disease Progression and Alters CD8+ T Cell Spatial Orientation and Density

S. Lockett, S. Ambs, S. Hewitt, 2022, bioRxiv.

The Structure of the Extracellular Domain of Triggering Receptor Expressed on Myeloid Cells Like Transcript-1 and Evidence for a Naturally Occurring Soluble Fragment*

J. Lubkowski, J. Gattis, A. Szyk, 2006, Journal of Biological Chemistry.

Paired Receptor Systems of the Innate Immune System

D. McVicar, Eriko Yamada, Daniel W. McVicar, 2008, Current protocols in immunology.

Identification of an elaborate NK-specific system regulating HLA-C expression

M. Carrington, S. Anderson, M. Ivarsson, 2018, PLoS genetics.

Monocyte chemotactic protein‐3 (MCP3) interacts with multiple leukocyte receptors: binding and signaling of MCP3 through shared as well as unique receptors on monocytes and neutrophils

Ji Ming Wang, D. Kuhns, A. Ben-Baruch, 1995, European journal of immunology.

Functional Association of FcɛRIγ With Arginine632 of Paired Immunoglobulin-Like Receptor (PIR)-A3 in Murine Macrophages

D. McVicar, L. Taylor, 1999 .

Nitric Oxide Modulates Metabolic Processes in the Tumor Immune Microenvironment

S. Lockett, D. Wink, S. Anderson, 2021, International journal of molecular sciences.

Paired inhibitory and activating receptor signals.

D. McVicar, L. Taylor, S. Paul, 2000, Reviews in immunogenetics.

Differential tyrosine phosphorylation of inhibitory versus activating Ly-49 receptor proteins and their recruitment of SHP-1 phosphatase.

S. Anderson, J. Ortaldo, D. McVicar, 1997, Journal of immunology.

Regulation of Ly49D/DAP12 Signal Transduction by Src-Family Kinases and CD4512

D. McVicar, L. Taylor, J. Willette-Brown, 2006, The Journal of Immunology.

CD 45 Transduction by Src-Family Kinases and Regulation of Ly 49 D / DAP 12 Signal and

D. McVicar, L. Taylor, J. Willette-Brown, 2006 .

repertoire usage in ITAM signaling, and influence on development of the Ly49 of B cells in natural killer cells reveals a novel signaling cassette, dual Analysis of the linker for activation of T cells and the linker for activation

D. Hodge, D. Burshtyn, Selinda J Orr, 2013 .

Analysis of the linker for activation of T cells and the linker for activation of B cells in natural killer cells reveals a novel signaling cassette, dual usage in ITAM signaling, and influence on development of the Ly49 repertoire.

D. Hodge, D. Burshtyn, Selinda J Orr, 2008, Blood.

Signaling through MHC in transgenic mice generates a population of memory phenotype cytolytic cells that lack TCR.

A. Rosenberg, P. Love, D. Morris, 2003, Blood.

Promiscuity of ligand binding in the human chemokine beta receptor family.

D. Kelvin, J. Wang, J. Oppenheim, 1993, Advances in experimental medicine and biology.

Complex regulation of the Csk homologous kinase (Chk) by IL-4 family cytokines and IFN-gamma in human peripheral blood monocytes.

T. Musso, D. McVicar, L. Taylor, 2004, Molecular immunology.

Treatment of recurrent malignant glioma by repeated intracerebral injections of human recombinant interleukin-2 alone or in combination with systemic interferon-α. Results of a phase I clinical trial

R. Merchant, H. Young, D. McVicar, 2004, Journal of Neuro-Oncology.

IL-4 and IL-13 induce Lsk, a Csk-like tyrosine kinase, in human monocytes

J. O’Shea, P. Ferrara, J. Ortaldo, 1994, The Journal of experimental medicine.

Identification of RANTES receptors on human monocytic cells: competition for binding and desensitization by homologous chemotactic cytokines

D. Kelvin, J. Wang, J. Oppenheim, 1993, The Journal of experimental medicine.

Rafting with the IL-12 receptor.

D. McVicar, 2008, Blood.

Initial characterization of TREM-like transcript (TLT)-1: a putative inhibitory receptor within the TREM cluster.

D. McVicar, A. Washington, L. Quigley, 2002, Blood.

Serum amyloid A induces calcium mobilization and chemotaxis of human monocytes by activating a pertussis toxin-sensitive signaling pathway.

J. Johnston, R. Badolato, D. Kelvin, 1995, Journal of immunology.

Cloning and expression of a second human natural killer cell granule tryptase, HNK‐Tryp‐2/granzyme 3

T. Sayers, M. Smyth, R. Wiltrout, 1996, Journal of leukocyte biology.

The Csk-like proteins Lsk, Hyl, and Matk represent the same Csk homologous kinase (Chk) and are regulated by stem cell factor in the megakaryoblastic cell line MO7e.

F. Ruscetti, W. Modi, J. Ortaldo, 1997, Growth factors.

Pathogen-specific loss of host resistance in mice lacking the IFN-γ-inducible gene IGTP

A. Sher, M. Bray, G. Woude, 2000 .

Inducible Nitric Oxide Synthase in the Carcinogenesis of Gastrointestinal Cancers.

D. Wink, R. Cheng, L. Ridnour, 2017, Antioxidants & redox signaling.

Pemphigus is associated with KIR3DL2 expression levels and provides evidence that KIR3DL2 may bind HLA‐A3 and A11 in vivo

M. Carrington, M. Petzl-Erler, Maureen P. Martin, 2015, European journal of immunology.

Lentiviral hematopoietic stem cell gene therapy for X-linked severe combined immunodeficiency

L. Notarangelo, J. Gray, D. Kuhns, 2016, Science Translational Medicine.

The ever‐expanding Ly49 gene family: repertoire and signaling

S. Anderson, J. Ortaldo, D. McVicar, 2001, Immunological reviews.

TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans.

A. Dutra, J. Lubkowski, P. Schwartzberg, 2009, The Journal of clinical investigation.

CD164 identifies CD4+ T cells highly expressing genes associated with malignancy in Sézary syndrome: the Sézary signature genes, FCRL3, Tox, and miR-214

A. Troxel, A. Rook, J. Takeshita, 2016, Archives of Dermatological Research.

Activation of peripheral large granular lymphocytes with the serine/threonine phosphatase inhibitor, okadaic acid

J. Ortaldo, D. McVicar, E. Bere, 1994, European journal of immunology.

HLA-C cell surface expression and control of HIV / AIDS correlate with a variant upstream of HLA-C

D. Ge, J. Goedert, M. Carrington, 2009 .

Androgen-mediated TGFβ expression suppresses anti-tumor neutrophil response in bone metastatic prostate cancer

Keqiang Chen, Ji Ming Wang, C. Morrissey, 2023, bioRxiv.

NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis

Ji Luo, David F. Stroncek, Chi Ma, 2016, Nature.

The killer immunoglobulin-like receptor gene cluster: tuning the genome for defense.

M. Carrington, Maureen P. Martin, D. McVicar, 2006, Annual review of genomics and human genetics.

Peritoneal tissue-resident macrophages are metabolically poised to engage microbes using tissue-niche fuels

P. Taylor, D. Kuhns, L. Davies, 2017, Nature Communications.

TREM and TREM-like receptors in inflammation and disease.

D. McVicar, J. Ford, Jill W. Ford, 2009, Current opinion in immunology.

Interleukin-1 and Interferon-γ Orchestrate β-Glucan-Activated Human Dendritic Cell Programming via IκB-ζ Modulation

A. Sher, A. Dzutsev, G. Trinchieri, 2014, PloS one.

Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2

J. Johnston, J. O’Shea, J. Ortaldo, 1994, Nature.

Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity.

H. Varmus, A. Sher, J. Debnath, 1999, Science.

Regulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7

J. Johnston, J. O’Shea, L. Varesio, 1995, The Journal of experimental medicine.

Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice.

D. Longo, J. O’Shea, A. Ochoa, 1992, Science.

The Csk homologous kinase, Chk, binds tyrosine phosphorylated paxillin in human blastic T cells.

D. McVicar, S. Grgurevich, A. Mikhael, 1999, Biochemical and biophysical research communications.

MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape

Sri H. Ramarathinam, Anthony W Purcell, Bosco K. Ho, 2017, Nature Structural &Molecular Biology.

Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1

J. Rossjohn, E. Gostick, J. Vivian, 2015, Journal of Virology.

Tumor-Infiltrating Myeloid Cells Co-Express TREM1 and TREM2 and Elevated TREM-1 Associates With Disease Progression in Renal Cell Carcinoma

J. Weiss, W. Linehan, B. Rini, 2022, Frontiers in Oncology.

Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression

Nimit L. Patel, J. Weiss, S. Durum, 2018, Nature Communications.

Advantages of q-PCR as a method of screening for gene targeting in mammalian cells using conventional and whole BAC-based constructs

A. Dutra, P. Liu, P. Schwartzberg, 2008, Nucleic acids research.

Inducible nitric oxide synthase-derived extracellular nitric oxide flux regulates proinflammatory responses at the single cell level

S. Lockett, G. Altan-Bonnet, D. Wink, 2019, Redox biology.

Differential basal protein tyrosine phosphorylation in natural killer (NK) and T cells: a biochemical correlate of lymphoid functional activity.

J. O’Shea, J. Ortaldo, K. Conlon, 1996, Cellular immunology.

Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL- 12

R. Rees, J. Johnston, J. O’Shea, 1995, The Journal of experimental medicine.

CD 164 identifies CD 4 + T cells highly expressing genes associated with malignancy in Sézary syndrome : the Sézary signature genes

A. Troxel, A. Rook, J. Takeshita, 2019 .

Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition

J. Rossjohn, J. Vivian, Philippa M. Saunders, 2016, The Journal of experimental medicine.

Mutational and Structural Analysis of KIR3DL1 Reveals a Lineage-Defining Allotypic Dimorphism That Impacts Both HLA and Peptide Sensitivity

J. Rossjohn, E. Gostick, S. Anderson, 2014, The Journal of Immunology.

In vivo expression of signaling proteins in reconstituted NK cells.

Selinda J Orr, D. McVicar, L. Quigley, 2009, Journal of immunological methods.

TLR-activated repression of Fe-S cluster biogenesis drives a metabolic shift and alters histone and tubulin acetylation.

T. Rouault, W. Tong, Erika M Palmieri, 2018, Blood advances.

Molecular cloning of lsk, a carboxyl-terminal src kinase (csk) related gene, expressed in leukocytes.

J. O’Shea, B. Lal, J. E. Staples, 1994, Oncogene.

A TREM family member, TLT-1, is found exclusively in the alpha-granules of megakaryocytes and platelets.

Edward H. Cho, D. McVicar, A. Washington, 2004, Blood.

DAP12-mediated Signal Transduction in Natural Killer Cells

W. Seaman, S. Anderson, R. Geahlen, 1998, The Journal of Biological Chemistry.

Systemic Nos2 Depletion and Cox inhibition limits TNBC disease progression and alters lymphoid cell spatial orientation and density

S. Ambs, S. Hewitt, D. Wink, 2022, Redox biology.

Orally administered β-glucan attenuates the Th2 response in a model of airway hypersensitivity

Selinda J Orr, D. McVicar, G. O’Connor, 2016, SpringerPlus.

Nitric Oxide in Macrophage Immunometabolism: Hiding in Plain Sight

D. Wink, Erika M Palmieri, D. McVicar, 2020, Metabolites.

A genome-wide screen uncovers multiple roles for mitochondrial nucleoside diphosphate kinase D in inflammasome activation

Eugen C. Buehler, I. Fraser, Sharat J. Vayttaden, 2021, Science Signaling.

Interaction of a dengue virus NS1‐derived peptide with the inhibitory receptor KIR3DL1 on natural killer cells

A. Nisalak, S. Kalayanarooj, S. Green, 2015, Clinical and experimental immunology.

The Interaction of KIR3DL1*001 with HLA Class I Molecules Is Dependent upon Molecular Microarchitecture within the Bw4 Epitope

T. Beddoe, J. Rossjohn, S. Gras, 2015, The Journal of Immunology.

Pemphigus is associated withKIR 3 DL 2 expression levels and provides evidence that KIR 3 DL 2 may bind HLA A 3 and A 11 in vivo

M. Carrington, M. Petzl-Erler, Maureen P. Martin, 2016 .

Mutation of Tec family kinases alters T helper cell differentiation

A. Sher, E. Schaeffer, P. Schwartzberg, 2001, Nature Immunology.

Soluble Trem-like Transcript-1 Regulates Leukocyte Activation and Controls Microbial Sepsis

F. Massin, C. Alauzet, S. Gibot, 2012, The Journal of Immunology.

In vitro analysis of the proliferative potential of T cells from patients with brain tumor: glioma-associated immunosuppression unrelated to intrinsic cellular defect.

R. Merchant, D. McVicar, D. Davis, 1992, Journal of neurosurgery.

Metabolic but not transcriptional regulation by PKM2 is important for natural killer cell responses

David K. Finlay, D. Finlay, Erika M Palmieri, 2020, bioRxiv.

Positive regulation of plasmacytoid dendritic cell function via Ly49Q recognition of class I MHC

A. Makrigiannis, L. Tai, S. Vidal, 2008, The Journal of experimental medicine.

memory phenotype cytolytic cells that lack TCR Signaling through MHC in transgenic mice generates a population of

P. Love, D. Morris, S. Amy, 2013 .

Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase

A. Lane, R. Higashi, D. Wink, 2020, Nature Communications.

Signaling and stress: The redox landscape in NOS2 biology.

D. Wink, C. Switzer, R. Cheng, 2015, Free radical biology & medicine.

Phenotypic heterogeneity in the gray platelet syndrome extends to the expression of TREM family member, TLT-1

P. Nurden, A. Nurden, E. Bermejo, 2008, Thrombosis and Haemostasis.

Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP.

A. Sher, G. V. Vande Woude, M. Bray, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Sepsis Microbial Leukocyte Activation and Controls Soluble Trem-like Transcript-1 Regulates

C. Alauzet, S. Gibot, B. Levy, 2022 .

Tyrosine Phosphorylation Disrupts Elongin Interaction and Accelerates SOCS3 Degradation*

J. Johnston, P. Heinrich, S. Haan, 2003, Journal of Biological Chemistry.

TREML4 Promotes Inflammatory Programs in Human and Murine Macrophages and Alters Atherosclerosis Lesion Composition in the Apolipoprotein E Deficient Mouse

A. Finn, F. Kolodgie, L. Biesecker, 2020, Frontiers in Immunology.

LAB/NTAL Facilitates Fungal/PAMP-induced IL-12 and IFN-γ Production by Repressing β-Catenin Activation in Dendritic Cells

G. Trinchieri, P. Taylor, Simon A. Jones, 2013, PLoS pathogens.

Autocrine IL-10 functions as a rheostat for M1 macrophage glycolytic commitment by tuning nitric oxide production☆☆☆

J. Weiss, D. Wink, S. Hussain, 2016, Redox biology.

IFN‐γ and androgens disrupt mitochondrial function in murine myocytes

H. Young, John M Fenimore, S. Yanpallewar, 2023, The Journal of pathology.

Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression

J. Weiss, S. Durum, Jung-Min Lee, 2018, Nature Communications.

Integrative DNA, RNA, and protein evidence connects TREML4 to coronary artery calcification.

Larry N. Singh, Andrew D. Johnson, J. Mullikin, 2014, American journal of human genetics.

TLR‐mediated signaling pathways circumvent the requirement for DAP12 in mast cells for the induction of inflammatory mediator release

Shoko Iwaki, D. Metcalfe, A. Gilfillan, 2010, European journal of immunology.

Analysis of Ly49 gene transcripts in mature NK cells supports a role for the Pro1 element in gene activation, not gene expression

S. Sen, S. Anderson, Maggie Cam, 2016, Genes and Immunity.

The myeloid receptor TREM2 exacerbates DSS-induced colitis and promotes colitis-associated cancer (TUM4P.916)

W. Linehan, B. Rini, J. Finke, 2014, Journal of Immunology.

IL-27 induces an IFN-like signature in murine macrophages which in turn modulate colonic epithelium

D. Wink, H. Young, S. Durum, 2023, Frontiers in Immunology.

Functional association of FcepsilonRIgamma with arginine(632) of paired immunoglobulin-like receptor (PIR)-A3 in murine macrophages.

D. McVicar, L. Taylor, 1999, Blood.

Corticosteroids inhibit the delivery of short-term activational pulses of phorbol ester and calcium ionophore to human peripheral T cells.

R. Merchant, D. McVicar, C. McCrady, 1992, Cellular immunology.

Androgen-mediated TGFβ expression suppresses anti-tumor neutrophil response in bone metastatic prostate cancer

Keqiang Chen, Ji Ming Wang, C. Morrissey, 2023, bioRxiv.

Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer

J. Weiss, S. Lockett, S. Ambs, 2017, Proceedings of the National Academy of Sciences.

Itaconic acid underpins hepatocyte lipid metabolism in non-alcoholic fatty liver disease in male mice

J. Weiss, N. Snyder, Erika M Palmieri, 2023, Nature Metabolism.

Interferon-gamma is Quintessential for NOS2 and COX2 Expression in ER- Breast Tumors that Lead to Poor Outcome

S. Ambs, Jenny C. Chang, S. Hewitt, 2023, bioRxiv.

Hemostasis, Thrombosis, and Vascular Biology Materials and Methods Cell Culture and Transfection

Edward H. Cho, D. McVicar, A. Washington, 2022 .

Hemostasis, Thrombosis, and Vascular Biology Materials and Methods Cell Culture and Transfection

Edward H. Cho, D. McVicar, A. Washington, 2022 .

This information is current as HLA and Peptide Sensitivity Allotypic Dimorphism That Impacts Both KIR 3 DL 1 Reveals a Lineage-Defining Mutational and Structural Analysis of

J. Rossjohn, E. Gostick, S. Anderson, 2014 .

Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis

A. Guarini, W. Lamers, B. Ghesquière, 2017, Cell reports.

Pyruvate dehydrogenase operates as an intramolecular nitroxyl generator during macrophage metabolic reprogramming

J. Weiss, T. Rouault, R. Holewinski, 2023, Nature communications.

Editorial: Metabolism Meets Function: Untangling the Cross-Talk Between Signaling and Metabolism

P. Porporato, A. Castegna, D. McVicar, 2020, Frontiers in Oncology.

Interferon-gamma is quintessential for NOS2 and COX2 expression in ER- breast tumors that lead to poor outcome

S. Ambs, S. Hewitt, D. Wink, 2023, Cell death & disease.

Interaction of a dengue virus NS1‐derived peptide with the inhibitory receptor KIR3DL1 on natural killer cells

A. Nisalak, S. Kalayanarooj, A. Rothman, 2015, Clinical and experimental immunology.

Nitric oxide dictates the reprogramming of carbon flux during M1 macrophage polarization

T. Fan, D. Wink, B. Ghesquière, 2018, Journal of Immunology.

structural analysis of KIR3DL1

E. Gostick, J. Vivian, J. Bridgeman, 2023 .

Delineates Differences in Signaling Thresholds Required for Lymphocyte Development and Maintenance

T. Chan, Selinda J Orr, D. McVicar, 2010 .

Interaction of a dengue virus NS1-derived peptide with the Interaction of a dengue virus NS1-derived peptide with the inhibitory receptor KIR3DL1 on natural killer cells inhibitory receptor KIR3DL1 on natural killer cells

A. Nisalak, S. Kalayanarooj, A. Rothman, 2023 .

Positive regulation of plasmacytoid dendritic cell function via Ly49Q recognition of class I MHC

A. Makrigiannis, L. Tai, S. Vidal, 2008, The Journal of experimental medicine.

Hemostasis, Thrombosis, and Vascular Biology Materials and Methods Cell Culture and Transfection

Edward H. Cho, D. McVicar, A. Washington, 2022 .