David Guay

发表

YB-1 promotes strand separation in vitro of duplex DNA containing either mispaired bases or cisplatin modifications, exhibits endonucleolytic activities and binds several DNA repair proteins.

M. Lebel, Isabelle Gaudreault, David Guay, 2004, Nucleic acids research.

Cell permeabilization using a non-thermal plasma

R. Leask, S. Coulombe, David Guay, 2009 .

Effects of Non‐thermal Plasmas on DNA and Mammalian Cells

R. Leask, S. Coulombe, David Guay, 2010 .

Use of inert gas jets to measure the forces required for mechanical gene transfection

R. Leask, S. Coulombe, David Guay, 2012, Biomedical engineering online.

Formation of a nuclear complex containing the p53 tumor suppressor, YB-1, and the Werner syndrome gene product in cells treated with UV light.

M. Lebel, Isabelle Gaudreault, David Guay, 2006, The international journal of biochemistry & cell biology.

The human endonuclease III enzyme is a relevant target to potentiate cisplatin cytotoxicity in Y‐box‐binding protein‐1 overexpressing tumor cells

C. Schmutte, C. Garand, M. Lebel, 2008, Cancer science.

Non-viral nucleic acid delivery methods

I. Slivac, David Guay, Bruno Gaillet, 2017, Expert opinion on biological therapy.

The strand separation and nuclease activities associated with YB-1 are dispensable for cisplatin resistance but overexpression of YB-1 in MCF7 and MDA-MB-231 breast tumor cells generates several chemoresistance signatures.

D. Bachvarov, E. Paquet, C. Garand, 2008, The international journal of biochemistry & cell biology.

Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia

D. Meyerholz, S. Krishnamurthy, C. Wohlford-Lenane, 2019, Nature Communications.

Membrane permeabilizing amphiphilic peptide delivers recombinant transcription factor and CRISPR-Cas9/Cpf1 ribonucleoproteins in hard-to-modify cells

A. Garnier, D. Roy, David Guay, 2018, PloS one.

Novel DNA mismatch-repair activity involving YB-1 in human mitochondria.

L. Rasmussen, V. Bohr, N. C. de Souza-Pinto, 2009, DNA repair.

Shuttle Peptide Delivers Base Editor RNPs to Rhesus Monkey Airway Epithelial Cells In Vivo

Gregory A. Newby, P. McCray, A. Tarantal, 2023, Research square.

An integrative approach to identify YB‐1‐interacting proteins required for cisplatin resistance in MCF7 and MDA‐MB‐231 breast cancer cells

Chris Sereduk, H. Yin, C. Sereduk, 2011, Cancer science.

NONO and RALY proteins are required for YB-1 oxaliplatin induced resistance in colon adenocarcinoma cell lines

H. Yin, Meraj Aziz, C. Sereduk, 2011, Molecular Cancer.

Genome Editing in Ferret Airway Epithelia Mediated by CRISPR/nucleases Delivered with Amphiphilic Shuttle Peptides.

Xiaoming Liu, M. Luo, David Guay, 2023, Human gene therapy.

An integrative approach to identify YB‐1‐interacting proteins required for cisplatin resistance in MCF7 and MDA‐MB‐231 breast cancer cells

H. Yin, C. Sereduk, C. Garand, 2011, Cancer science.

KLRC1 knockout overcomes HLA-E-mediated inhibition and improves NK cell antitumor activity against solid tumors

Elie Haddad, Yuanyi Li, David Guay, 2023, Frontiers in immunology.

Shuttle peptide delivers base editor RNPs to rhesus monkey airway epithelial cells in vivo

Gregory A. Newby, D. Meyerholz, G. Rettig, 2023, Nature communications.