Y. Hsueh

发表

Beyond defense: regulation of neuronal morphogenesis and brain functions via Toll-like receptors

Chiung-Ya Chen, Yi-Chun Shih, Yun-Fen Hung, 2019, Journal of Biomedical Science.

Tlr7 deletion alters expression profiles of genes related to neural function and regulates mouse behaviors and contextual memory

Ting-Fang Wang, Chiung-Ya Chen, Yun-Fen Hung, 2018, Brain, Behavior, and Immunity.

Interhemispheric Connectivity Potentiates the Basolateral Amygdalae and Regulates Social Interaction and Memory.

John Y. Lin, M. Tao, Y. Hsueh, 2019, Cell reports.

Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain

Pei-Lin Cheng, Y. Hsueh, Tzyy-Nan Huang, 2020, The Journal of cell biology.

Intrinsic disorder codes for leaps of protein expression

Ting-Fang Wang, Chiung-Ya Chen, Y. Hsueh, 2020 .

PINK1 Interacts with VCP/p97 and Activates PKA to Promote NSFL1C/p47 Phosphorylation and Dendritic Arborization in Neurons

M. H. Cheng, I. Bahar, C. Chu, 2018, eNeuro.

Phase separation and zinc-induced transition modulate synaptic distribution and association of autism-linked CTTNBP2 and SHANK3

K. Hsia, Ting-Fang Wang, Sahana Shankar, 2022, Nature Communications.

Editorial: Autism Signaling Pathways

Yu-Chih Lin, Y. Hsueh, 2021, Frontiers in Cellular Neuroscience.

CTTNBP2 Controls Synaptic Expression of Zinc-Related Autism-Associated Proteins and Regulates Synapse Formation and Autism-like Behaviors.

Y. Hsueh, Tzyy-Nan Huang, Ming-hui Lin, 2020, Cell reports.

Anterior Commissure Regulates Neuronal Activity of Amygdalae and Influences Locomotor Activity, Social Interaction and Fear Memory in Mice

Y. Hsueh, Tzyy-Nan Huang, Tsan-Ting Hsu, 2020, Frontiers in Molecular Neuroscience.

Haploinsufficiency of autism causative gene Tbr1 impairs olfactory discrimination and neuronal activation of the olfactory system in mice

J. Lerch, L. Qiu, Y. Hsueh, 2019, Molecular Autism.

Synaptic Formation, Neural Circuits and Neurodevelopmental Disorders Controlled by Signaling, Translation, and Epigenetic Regulation

Y. Hsueh, 2019, Developmental neurobiology.

A versatile player.

Y. Hsueh, 2011, Journal of molecular biology.

The role of the MAGUK protein CASK in neural development and synaptic function.

Y. Hsueh, 2006, Current medicinal chemistry.

Postsynaptic SDC2 induces transsynaptic signaling via FGF22 for bidirectional synaptic formation

H. Umemori, Y. Hsueh, Hsiao-Tang Hu, 2016, Scientific Reports.

VCP and ATL1 regulate endoplasmic reticulum and protein synthesis for dendritic spine formation

Y. Hsueh, Yu-Tzu Shih, 2016, Nature Communications.

Bcl11A/CTIP1 mediates the effect of the glutamate receptor on axon branching and dendrite outgrowth

Chiung-Ya Chen, Y. Hsueh, T. Kuo, 2010, Journal of neurochemistry.

TLR7 Negatively Regulates Dendrite Outgrowth through the Myd88–c-Fos–IL-6 Pathway

Chiung-Ya Chen, Y. Hsueh, Hsin-Yu Liu, 2013, The Journal of Neuroscience.

Isolation and characterization of nuclear proteins that bind to T cell receptor V beta decamer motif.

C. Chung, M. Lai, Y. Hsueh, 1992, Journal of immunology.

Atypical signaling defects prevent IL-2 gene expression in lpr/lpr CD4-CD8- cells.

S. Han, M. Lai, S. Hsu, 1998, Journal of biomedical science.

Social behaviors and contextual memory of Vcp mutant mice are sensitive to nutrition and can be ameliorated by amino acid supplementation

Y. Hsueh, Tzyy-Nan Huang, Yu-Tzu Shih, 2020, iScience.

Valosin-containing protein and neurofibromin interact to regulate dendritic spine density.

Ming‐Jen Lee, Chiung-Ya Chen, Hsiao-Fang Wang, 2011, The Journal of clinical investigation.

Neurofibromin interacts with CRMP-2 and CRMP-4 in rat brain.

Yi-Ling Lin, Y. Hsueh, 2008, Biochemical and biophysical research communications.

Bipartite Interaction between Neurofibromatosis Type I Protein (Neurofibromin) and Syndecan Transmembrane Heparan Sulfate Proteoglycans

M. Sheng, M. Volta, R. Roberts, 2001, The Journal of Neuroscience.

Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN

J. Milbrandt, Jean J. Zhao, R. Segal, 2021, The Journal of cell biology.

Transcriptomic Analysis and C-Terminal Epitope Tagging Reveal Differential Processing and Signaling of Endogenous TLR3 and TLR7

Ting-Fang Wang, Chiung-Ya Chen, Ting-Fang Chou, 2021, Frontiers in Immunology.

Psd-95 and Sap97 Exhibit Distinct Mechanisms for Regulating K+ Channel Surface Expression and Clustering

J. Trimmer, M. Sheng, Eunjoon Kim, 2000, The Journal of cell biology.

Expression of zinc finger transcription factor Bcl11A/Evi9/CTIP1 in rat brain

Y. Hsueh, Ting-Yu Kuo, 2007, Journal of neuroscience research.

Sex-biased response to and brain cell infection by SARS-CoV-2 in a highly susceptible human ACE2 transgenic model

J. Jan, Y. Chou, Chiung-Ya Chen, 2021, bioRxiv.

Impact of glycosylation on a broad-spectrum vaccine against SARS-CoV-2

Chi‐Huey Wong, Cheng-Wei Cheng, Che Ma, 2021, bioRxiv.

TLR7 and IL-6 differentially regulate the effects of rotarod exercise on the transcriptomic profile and neurogenesis to influence anxiety and memory

Yun-Fen Hung, Y. Hsueh, 2021, iScience.

Atypical Signaling Defects Prevent IL-2 Gene Expression in lpr/lpr CD4–CD8– Cells

Hong-Erh Liang, M. Lai, S. Hsu, 1998, Journal of Biomedical Science.

Deletion of the Inflammasome Sensor Aim2 Mitigates Aβ Deposition and Microglial Activation but Increases Inflammatory Cytokine Expression in an Alzheimer Disease Mouse Model

Yun-Fen Hung, Y. Hsueh, Hsin-Yu Liu, 2017, Neuroimmunomodulation.

Slit Promotes Branching and Elongation of Neurites of Interneurons But Not Projection Neurons from the Developing Telencephalon

Y. Rao, Jane Y. Wu, Y. Hsueh, 2002, Molecular and Cellular Neuroscience.

Requirement of N-terminal Cysteines of PSD-95 for PSD-95 Multimerization and Ternary Complex Formation, but Not for Binding to Potassium Channel Kv1.4*

M. Sheng, Y. Hsueh, M. Sheng, 1999, The Journal of Biological Chemistry.

Disulfide-Linked Head-to-Head Multimerization in the Mechanism of Ion Channel Clustering by PSD-95

M. Sheng, Eunjoon Kim, Y. Hsueh, 1997, Neuron.

Trans-synaptic zinc mobilization improves social interaction in two mouse models of autism through NMDAR activation

Eunjoon Kim, J. Koh, Changuk Chung, 2015, Nature Communications.

Chapter 9 Anchoring of glutamate receptors at the synapse

M. Sheng, Y. Hsueh, 1998 .

Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2

M. Sheng, Ting-Fang Wang, Yi-Ping Hsueh, 2000, Nature.

Regulated Expression and Subcellular Localization of Syndecan Heparan Sulfate Proteoglycans and the Syndecan-Binding Protein CASK/LIN-2 during Rat Brain Development

M. Sheng, Y. Hsueh, 1999, The Journal of Neuroscience.

Targeted Deletion of CASK-Interacting Nucleosome Assembly Protein Causes Higher Locomotor and Exploratory Activities

Y. Hsueh, Wen-Chuan Chung, Tzyy‐Nan Huang, 2011, Neurosignals.

Bcl11A/CTIP1 regulates expression of DCC and MAP1b in control of axon branching and dendrite outgrowth

Y. Hsueh, Ting-Yu Kuo, Chen-Jei Hong, 2009, Molecular and Cellular Neuroscience.

T‐Brain‐1 – A Potential Master Regulator in Autism Spectrum Disorders

Y. Hsueh, Hsiu-Chun Chuang, Tzyy‐Nan Huang, 2015, Autism research : official journal of the International Society for Autism Research.

Protein synthesis as a modifiable target for autism‐related dendritic spine pathophysiologies

Y. Hsueh, Ming-Hsuan Lu, 2021, The FEBS journal.

Brain-specific transcriptional regulator T-brain-1 controls brain wiring and neuronal activity in autism spectrum disorders

Y. Hsueh, Tzyy‐Nan Huang, 2015, Front. Neurosci..

Neuronal excitation upregulates Tbr1, a high-confidence risk gene of autism, mediating Grin2b expression in the adult brain

Tzyy-Nan Huang, Yi-Ping Hsueh, Y. Hsueh, 2014, Front. Cell. Neurosci..

Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality

S. Chou, Chiung-Ya Chen, Hsiao-Fang Wang, 2014, Nature Neuroscience.

Dietary zinc supplementation rescues fear-based learning and synaptic function in the Tbr1+/− mouse model of autism spectrum disorders

W. Abraham, J. Montgomery, Kevin Lee, 2022, Molecular Autism.

Heterodimeric complexes of Hop2 and Mnd1 function with Dmc1 to promote meiotic homolog juxtaposition and strand assimilation.

A. H. Wang, H. Olivares, C. Leng, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Trichoderma reesei Rad51 tolerates mismatches in hybrid meiosis with diverse genome sequences

Hung-Wen Li, Ting-Fang Wang, H. Yeh, 2021, Proceedings of the National Academy of Sciences.

Tbr1 Regulates Differentiation of the Preplate and Layer 6

J. Rubenstein, M. Sheng, R. Hevner, 2001, Neuron.

The Involvement of Neuron-Specific Factors in Dendritic Spinogenesis: Molecular Regulation and Association with Neurological Disorders

Y. Hsueh, Hsiao-Tang Hu, Yu-Tzu Shih, 2015, Neural plasticity.

CTTNBP2, but not CTTNBP2NL, regulates dendritic spinogenesis and synaptic distribution of the striatin–PP2A complex

Yi-Ping Hsueh, Chiung-Ya Chen, Y. Hsueh, 2012, Molecular biology of the cell.

Autism-linked mutations of CTTNBP2 reduce social interaction and impair dendritic spine formation via diverse mechanisms

B. Chen, Y. Hsueh, Pu-Yun Shih, 2020, Acta neuropathologica communications.

c-Jun N-terminal Kinase but Not Mitogen-activated Protein Kinase Is Sensitive to cAMP Inhibition in T Lymphocytes (*)

Y. Hsueh, Mingjun Lai, 1995, The Journal of Biological Chemistry.

From neurodevelopment to neurodegeneration: the interaction of neurofibromin and valosin-containing protein/p97 in regulation of dendritic spine formation

Y. Hsueh, 2012, Journal of Biomedical Science.

Vcp Overexpression and Leucine Supplementation Increase Protein Synthesis and Improve Fear Memory and Social Interaction of Nf1 Mutant Mice.

Y. Hsueh, Hsiao-Tang Hu, Yu-Tzu Shih, 2020, Cell reports.

Calcium/calmodulin‐dependent serine protein kinase (CASK) is a new intracellular modulator of P2X3 receptors

E. Fabbretti, A. Nistri, N. Birsa, 2013, Journal of neurochemistry.

The involvement of endoplasmic reticulum formation and protein synthesis efficiency in VCP- and ATL1-related neurological disorders

Y. Hsueh, Yu-Tzu Shih, 2018, Journal of Biomedical Science.

Cortactin-binding protein 2 increases microtubule stability and regulates dendritic arborization

Y. Hsueh, Yi-Kai Chen, Sue-Ping Lee, 2014, Journal of Cell Science.

Endosomal TLR3, TLR7, and TLR8 control neuronal morphology through different transcriptional programs

Chiung-Ya Chen, Yi-Chun Shih, Yun-Fen Hung, 2018, The Journal of cell biology.

Direct Interaction of CASK/LIN-2 and Syndecan Heparan Sulfate Proteoglycan and Their Overlapping Distribution in Neuronal Synapses

R. Weinberg, M. Sheng, V. Kharazia, 1998, The Journal of cell biology.

GKAP, a Novel Synaptic Protein That Interacts with the Guanylate Kinase-like Domain of the PSD-95/SAP90 Family of Channel Clustering Molecules

M. Sheng, A. Craig, Eunjoon Kim, 1997, The Journal of cell biology.

Mice lacking cyclin‐dependent kinase‐like 5 manifest autistic and ADHD‐like behaviors

Wenlin Liao, Y. Hsueh, Tzyy‐Nan Huang, 2017, Human molecular genetics.

Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models

Cheng-Wei Cheng, Che Ma, Chung-Yi Wu, 2022, Science Translational Medicine.

Syndecan-2 induces filopodia and dendritic spine formation via the neurofibromin–PKA–Ena/VASP pathway

Yi-Ling Lin, Y. Hsueh, Chen-Jei Hong, 2007, The Journal of cell biology.

TLR7 Is Critical for Anti-Viral Humoral Immunity to EV71 Infection in the Spinal Cord

Jen-Ren Wang, Y. Hsueh, F. Liao, 2021, Frontiers in Immunology.

AIM 2 inflammasomes regulate neuronal morphology and influence anxiety and memory in mice

Y. Hsueh, Hsin-Yu Liu, Pei-Jung Wu, 2016, Scientific Reports.

Blimp-1-Mediated Pathway Promotes Type I IFN Production in Plasmacytoid Dendritic Cells by Targeting to Interleukin-1 Receptor-Associated Kinase M

Y. Ko, Yi-Ling Lin, Jian-Jong Liang, 2018, Front. Immunol..

TLR3 downregulates expression of schizophrenia gene Disc1 via MYD88 to control neuronal morphology

Chiung-Ya Chen, Y. Hsueh, Hsin-Yu Liu, 2016, EMBO reports.

The microRNAs Let7c and miR21 are recognized by neuronal Toll-like receptor 7 to restrict dendritic growth of neurons

Yun-Fen Hung, Y. Hsueh, Hsin-Yu Liu, 2015, Experimental Neurology.

SUMOylation of the MAGUK protein CASK regulates dendritic spinogenesis

Yi-Ling Lin, Y. Hsueh, Hsu-Wen Chao, 2008, The Journal of cell biology.

Transcriptional Modification by a CASK-Interacting Nucleosome Assembly Protein

Guey-Shin Wang, M. Sheng, Hsin-Yi Huang, 2004, Neuron.

CD28-costimulation activates cyclic AMP-responsive element-binding protein in T lymphocytes.

S. Ng, M. Lai, Y. Hsueh, 1997, Journal of immunology.

Sarm1 deficiency impairs synaptic function and leads to behavioral deficits, which can be ameliorated by an mGluR allosteric modulator

Chiung-Ya Chen, Y. Hsueh, Hsiao-Tang Hu, 2014, Front. Cell. Neurosci..

X‐linked mental retardation gene CASK interacts with Bcl11A/CTIP1 and regulates axon branching and outgrowth

Y. Hsueh, Hsu-Ling Chien, Ting-Yu Kuo, 2010, Journal of neuroscience research.

Neural activity‐ and development‐dependent expression and distribution of CASK interacting nucleosome assembly protein in mouse brain

Guey-Shin Wang, Y. Hsueh, Chia-Wen Lin, 2006, The Journal of comparative neurology.

Identification of Tbr‐1/CASK complex target genes in neurons

Guey-Shin Wang, J. Rubenstein, R. Hevner, 2004, Journal of neurochemistry.

Neurofibromin signaling and synapses.

Y. Hsueh, 2007, Journal of biomedical science.

An Intramolecular Interaction between Src Homology 3 Domain and Guanylate Kinase-Like Domain Required for Channel Clustering by Postsynaptic Density-95/SAP90

M. Sheng, Eunjoon Kim, Hyewon Shin, 2000, The Journal of Neuroscience.

Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology

S. Jiang, Chiung-Ya Chen, Y. Hsueh, 2011, The Journal of cell biology.

Calcium/calmodulin-dependent serine protein kinase (CASK), a protein implicated in mental retardation and autism-spectrum disorders, interacts with T-Brain-1 (TBR1) to control extinction of associative memory in male mice

Y. Hsueh, Tzyy‐Nan Huang, 2017, Journal of psychiatry & neuroscience : JPN.

Calcium/calmodulin‐dependent serine protein kinase and mental retardation

Y. Hsueh, 2009, Annals of neurology.

Merlin cooperates with neurofibromin and Spred1 to suppress the Ras-Erk pathway.

Hongchuan Jin, H. Morrison, Y. Hsueh, 2020, Human molecular genetics.

Innate immune responses regulate morphogenesis and degeneration: roles of Toll-like receptors and Sarm1 in neurons

Chiung-Ya Chen, Y. Hsueh, Hsin-Yu Liu, 2014, Neuroscience Bulletin.

SARS-CoV-2 D614 and G614 spike variants impair neuronal synapses and exhibit differential fusion ability

Y. Chou, Chiung-Ya Chen, Y. Hsueh, 2020, bioRxiv.

Cortactin-Binding Protein 2 Modulates the Mobility of Cortactin and Regulates Dendritic Spine Formation and Maintenance

Y. Hsueh, Yi-Kai Chen, 2012, The Journal of Neuroscience.

CASK phosphorylation by PKA regulates the protein–protein interactions of CASK and expression of the NMDAR2b gene

Y. Hsueh, Hui-Ping Chang, Tzyy‐Nan Huang, 2010, Journal of neurochemistry.

Cdk5 Promotes Synaptogenesis by Regulating the Subcellular Distribution of the MAGUK Family Member CASK

L. Tsai, R. Neve, J. Volker, 2007, Neuron.

Overexpression of activation transcriptional factor 1 in lymphomas and in activated lymphocytes.

M. Lai, Y. Hsueh, 1995, Journal of immunology.

Innate immune responses regulate morphogenesis and degeneration: roles of Toll-like receptors and Sarm1 in neurons

Chiung-Ya Chen, Y. Hsueh, Hsin-Yu Liu, 2014, Neuroscience Bulletin.

Tlr 7 Deletion Selectively Ameliorates Spatial Learning but does not Influence Aβ Deposition and Inflammatory Response in an Alzheimer ’ s Disease Mouse Model

Yun-Fen Hung, Y. Hsueh, Hsin-Yu Liu, 2017 .

Neuronally-expressed Sarm1 regulates expression of inflammatory and antiviral cytokines in brains

Chiung-Ya Chen, Y. Hsueh, Hsin-Yu Liu, 2014, Innate immunity.

SARM1 detection in myelinating glia: sarm1/Sarm1 is dispensable for PNS and CNS myelination in zebrafish and mice

R. Barker, R. Franklin, K. Monk, 2023, Frontiers in Cellular Neuroscience.

SARM1 detection in oligodendrocytes but not Schwann cells though sarm1/Sarm1 deletion does not perturb CNS nor PNS myelination in zebrafish and mice

R. Barker, R. Franklin, K. Monk, 2022, bioRxiv.

Sarm1, a neuronal inflammatory regulator, controls social interaction, associative memory and cognitive flexibility in mice

Y. Hsueh, Chia-Wen Lin, 2014, Brain, Behavior, and Immunity.

Calcium influx and postsynaptic proteins coordinate the dendritic filopodium‐spine transition

Y. Hsueh, Hsiao-Tang Hu, 2014, Developmental neurobiology.

The Src–ZNRF1 axis controls TLR3 trafficking and interferon responses to limit lung barrier damage

Ya-Min Tsai, Sui‐Yuan Chang, Chih-Yuan Lee, 2023, The Journal of experimental medicine.

Cytoplasmic distribution of T-box transcription factor Tbr-1 in adult rodent brain

Y. Hsueh, Chen-Jei Hong, 2007, Journal of Chemical Neuroanatomy.

RNase A Promotes Proliferation of Neuronal Progenitor Cells via an ERK-Dependent Pathway

Wei-ping Li, Chiung-Ya Chen, Yun-Fen Hung, 2018, Front. Mol. Neurosci..

Quantification of the density and morphology of dendritic spines and synaptic protein distribution using Thy1-YFP transgenic mice

Y. Hsueh, Tzyy‐Nan Huang, Yung-Jui Lin, 2023, STAR protocols.

Transcriptional Regulation of the Tbr1-CASK-CINAP Protein Complex in Response to Neuronal Activity

Y. Hsueh, 2008 .

Anchoring of glutamate receptors at the synapse.

Y. Hsueh, M. Sheng, 1998, Progress in brain research.

From neurodevelopment to neurodegeneration: the interaction of neurofibromin and valosin-containing protein/p97 in regulation of dendritic spine formation

Y. Hsueh, 2012, Journal of Biomedical Science.

The involvement of endoplasmic reticulum formation and protein synthesis efficiency in VCP- and ATL1-related neurological disorders

Y. Hsueh, Yu-Tzu Shih, 2018, Journal of Biomedical Science.

CASK associates with glutamate receptor interacting protein and signaling molecules.

Y. Hsueh, Chen-Jei Hong, 2006, Biochemical and biophysical research communications.

Mice Deficient in Collapsin Response Mediator Protein-1 Exhibit Impaired Long-Term Potentiation and Impaired Spatial Learning and Memory

J. Shih, Shu-Wha Lin, W. Fu, 2007, The Journal of Neuroscience.

CASK point mutation regulates protein-protein interactions and NR2b promoter activity.

Y. Hsueh, Tzyy‐Nan Huang, 2009, Biochemical and biophysical research communications.

Beyond defense: regulation of neuronal morphogenesis and brain functions via Toll-like receptors

Chiung-Ya Chen, Yi-Chun Shih, Yun-Fen Hung, 2019, Journal of Biomedical Science.

KLHL17/Actinfilin, a brain-specific gene associated with infantile spasms and autism, regulates dendritic spine enlargement

Y. Hsueh, Hsiao-Tang Hu, Tzyy‐Nan Huang, 2020, Journal of Biomedical Science.

Eph Receptors, Ephrins, and PDZs Gather in Neuronal Synapses

M. Sheng, Y. Hsueh, 1998, Neuron.

Sex bias in social deficits, neural circuits and nutrient demand in Cttnbp2 autism models

J. Lerch, J. Ellegood, Y. Hsueh, 2022, Brain : a journal of neurology.

Neuron-specific regulation on F-actin cytoskeletons

Y. Hsueh, 2012, Communicative & integrative biology.