Michael Hedvat

发表

The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors.

Hua Yu, Hong Xin, Minwei Ye, 2009, Cancer cell.

Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24–mediated toxicity

P. Fisher, John Calvin Reed, P. Dent, 2011, Proceedings of the National Academy of Sciences.

Enhanced delivery of mda‐7/IL‐24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the apogossypol derivative BI‐97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells

P. Fisher, John Calvin Reed, P. Dent, 2012, Journal of cellular physiology.

Targeting Mcl-1 for the therapy of cancer

P. Fisher, John Calvin Reed, P. Dent, 2011, Expert opinion on investigational drugs.

Endoplasmic Reticulum Protein Bi-1 Regulates Ca 2+ -mediated Bioenergetics to Promote Autophagy

D. Green, V. Nizet, P. Fisher, 2022 .

697 Tumor-targeted CD28 costimulatory bispecific antibodies enhance T cell activation in solid tumors

J. Desjarlais, R. Rashid, C. Bonzon, 2020, Journal for ImmunoTherapy of Cancer.

Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NF-ĸB signaling, and synergizes with an ERK inhibitor.

R. Jove, Y. Yen, A. Scuto, 2012, Cancer biology & therapy.

Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas

R. Jove, J. Mirosevich, Fan Yang, 2008, Molecular Cancer Therapeutics.

Inhibition of HER-kinase activation prevents ERK-mediated degradation of PPARgamma.

D. Agus, D. Carson, M. Corr, 2004, Cancer cell.

Sunitinib Induces Apoptosis and Growth Arrest of Medulloblastoma Tumor Cells by Inhibiting STAT3 and AKT Signaling Pathways

Hua Yu, Fan Yang, H. Xin, 2010, Molecular Cancer Research.

Sorafenib Induces Growth Arrest and Apoptosis of Human Glioblastoma Cells through the Dephosphorylation of Signal Transducers and Activators of Transcription 3

R. Jove, A. Scuto, Fan Yang, 2010, Molecular Cancer Therapeutics.

Role of Excitatory Amino Acid Transporter‐2 (EAAT2) and glutamate in neurodegeneration: Opportunities for developing novel therapeutics

P. Fisher, John Calvin Reed, Seok-Geun Lee, 2011, Journal of cellular physiology.

Selected approaches for rational drug design and high throughput screening to identify anti-cancer molecules.

Bainan Wu, Maurizio Pellecchia, Martin G Pomper, 2012, Anti-cancer agents in medicinal chemistry.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Charles J. Vaske, Rohan N. Borkar, Brian D. Kelly, 2016, Journal of Immunotherapy for Cancer.

Antiangiogenic and antimetastatic activity of JAK inhibitor AZD1480.

R. Figlin, Hua Yu, R. Jove, 2011, Cancer research.

Alkylation of cysteine 468 in Stat3 defines a novel site for therapeutic development.

Yate-Ching Yuan, R. Jove, N. Vaidehi, 2011, ACS chemical biology.

Microenvironment and Immunology Antiangiogenic and Antimetastatic Activity of JAK Inhibitor AZD 1480

R. Figlin, Hua Yu, R. Jove, 2011 .

Abstract 2784: Simultaneous checkpoint-checkpoint or checkpoint-costimulatory receptor targeting with bispecific antibodies promotes enhanced human T cell activation

J. Desjarlais, Alex Nisthal, R. Varma, 2018, Immunology.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Charles J. Vaske, Rohan N. Borkar, David M. Schauder, 2016, Journal for ImmunoTherapy of Cancer.

Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24–mediated toxicity

P. Fisher, John Calvin Reed, P. Dent, 2011, Proceedings of the National Academy of Sciences.