Y. H. Kim

发表

Target modulation and pharmacokinetics/pharmacodynamics translation of the BTK inhibitor poseltinib for model-informed phase II dose selection

A. Pustilnik, M. Linnik, Y. Koh, 2021, Scientific Reports.

HM71224, a selective Bruton’s tyrosine kinase inhibitor, attenuates the development of murine lupus

K. Hwang, Joo-Yun Byun, S. Jang, 2017, Arthritis Research & Therapy.

HM71224, a novel Bruton’s tyrosine kinase inhibitor, suppresses B cell and monocyte activation and ameliorates arthritis in a mouse model: a potential drug for rheumatoid arthritis

E. Lee, Yeong-Wook Song, J. Park, 2016, Arthritis Research & Therapy.

Eflapegrastim Enhanced Efficacy Compared to Pegfilgrastim in Neutropenic Rats Supports Potential for Same-Day Dosing.

J. Barrett, S. Lakshmikanthan, Y. H. Kim, 2020, Experimental hematology.

Synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel FMS inhibitors.

Young Hoon Kim, K. Hwang, S. Jang, 2019, Bioorganic & medicinal chemistry letters.

Antitumor activity of HM781‐36B, a highly effective pan‐HER inhibitor in erlotinib‐resistant NSCLC and other EGFR‐dependent cancer models

Jongmin Park, Young Hoon Kim, Kwang-Ok Lee, 2012, International journal of cancer.

Synthesis of Vinyl Sulfone-tethered Proline Derivatives as Highly Selective Cathepsin S Inhibitors

Doran Kim, K. Min, Ji-Young Song, 2014 .

Synthesis of proline analogues as potent and selective cathepsin S inhibitors.

K. Min, Ji-Young Song, Y. H. Kim, 2013, Bioorganic & medicinal chemistry letters.

Synergistic Effects of BTK Inhibitor HM71224 and Methotrexate in a Collagen-induced Arthritis Rat Model

Hyung Sik Kim, S. Jang, Y. H. Kim, 2021, In Vivo.

Therapeutic Effects of Bruton’s Tyrosine Kinase Inhibitor HM71224 as Monotherapy and in Combination with Methotrexate on Collagen-Induced Arthritis in Rats

Ha Hyung Kim, Joo-Yun Byun, Y. H. Kim, 2020 .

Synthesis and Evaluation of a 3, 4‐dihydro‐2H ‐benzoxazine Derivative as a Potent CDK9 Inhibitor for Anticancer Therapy

Y. Chun, Joo-Yun Byun, Y. H. Kim, 2021 .

Discovery of a novel Her-1/Her-2 dual tyrosine kinase inhibitor for the treatment of Her-1 selective inhibitor-resistant non-small cell lung cancer.

Ji Yeon Song, Chang Gon Lee, Gwan Sun Lee, 2009, Journal of medicinal chemistry.

Abstract LB-100: Discovery of HM61713 as an orally available and mutant EGFR selective inhibitor

Ji Yeon Song, Jaeho Lee, J. Son, 2014 .

of Multiple Tumor Types Tyrosine Kinase Catalysis , Tumor Vascularization , and Growth Endothelial Growth Factor Receptor ( Flk-1 / KDR ) That Inhibits SU 5416 Is a Potent and Selective Inhibitor of the Vascular

A. Ullrich, G. Mcmahon, W. Risau, 1998 .

DiscoveryofANovelHer-1/Her-2DualTyrosineKinaseInhibitorfortheTreatmentofHer-1Selective Inhibitor-Resistant Non-small Cell Lung Cancer

Ji Yeon Song, Chang Gon Lee, Gwan Sun Lee, 2009 .

Synthesis of Quinazoline Analogues with Differential Activity for HER2‐overexpressing Breast Cancer Cells

K. Min, S. Jang, Y. H. Kim, 2015 .

Aminostyrylbenzofuran Directly Reduces Oligomeric Amyloid-β and Reverses Cognitive Deficits in Alzheimer Transgenic Mice

Dong Jin Kim, Jae Yang Kong, Young Hoon Kim, 2014, PloS one.

Belvarafenib penetrates the BBB and shows potent antitumor activity in a murine melanoma brain metastasis model

Jisook Kim, J. Mao, M. Dolton, 2023, Clinical & Experimental Metastasis.

Synthesis and anti-tumor activity of imidazopyrazines as TAK1 inhibitors.

K. Min, S. Jang, Y. H. Kim, 2019, European journal of medicinal chemistry.

Abstract 2606: Antitumor activity of the selective RAF inhibitor HM95573 in melanoma

Jaeho Lee, Su-Hyeon Kim, Y. H. Kim, 2015 .

Discovery of orally active sulfonylphenyl thieno[3,2-d]pyrimidine derivatives as GPR119 agonists.

K. Min, Y. H. Kim, K. Suh, 2023, European journal of medicinal chemistry.

Synthesis of proline analogues as potent and selective cathepsin S inhibitors.

K. Min, Y. H. Kim, K. Suh, 2013, Bioorganic & medicinal chemistry letters.

Pharmacological evaluation of HM41322, a novel SGLT1/2 dual inhibitor, in vitro and in vivo

Y. H. Kim, K. Suh, S. Sim, 2018, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.