M. Edwards

发表

Synthesis and antiviral activity of fatty acyl conjugates of remdesivir against severe acute respiratory syndrome coronavirus 2 and Ebola virus

R. Davey, K. Parang, C. Basler, 2021, European Journal of Medicinal Chemistry.

VP 24-Karyopherin alpha binding affinities differ between Ebolavirus species , nfluencing interferon inhibition and VP 24 stability

D. Leung, G. Amarasinghe, M. Edwards, 2017 .

VP24-Karyopherin Alpha Binding Affinities Differ between Ebolavirus Species, Influencing Interferon Inhibition and VP24 Stability

C. Basler, D. Leung, G. Amarasinghe, 2016, Journal of Virology.

Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses

R. Davey, P. Luthra, C. Basler, 2018, Antiviral research.

Dimerization Controls Marburg Virus VP24-dependent Modulation of Host Antioxidative Stress Responses.

M. Gross, Hao Zhang, Britney Johnson, 2016, Journal of molecular biology.

Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses

R. Pappu, P. Luthra, C. Basler, 2017, Nature Microbiology.

Henipavirus W Proteins Interact with 14-3-3 To Modulate Host Gene Expression

J. Forwood, C. Basler, I. Messaoudi, 2020, Journal of Virology.

Impact of Měnglà Virus Proteins on Human and Bat Innate Immune Pathways

P. Luthra, C. Basler, Timothy R Keiffer, 2019, Journal of Virology.

High-Throughput Minigenome System for Identifying Small-Molecule Inhibitors of Ebola Virus Replication.

M. Shaw, C. Basler, A. Bukreyev, 2015, ACS infectious diseases.

Structural basis for Marburg virus VP35–mediated immune evasion mechanisms

Z. Otwinowski, Gai Liu, C. Basler, 2012, Proceedings of the National Academy of Sciences.

Marburg Virus VP30 Is Required for Transcription Initiation at the Glycoprotein Gene

R. Davey, C. Basler, M. Edwards, 2022, mBio.

Marburg Virus VP24 Protein Relieves Suppression of the NF-κB Pathway Through Interaction With Kelch-like ECH-Associated Protein 1.

C. Basler, M. Edwards, 2015, The Journal of infectious diseases.

Small molecule compounds that inhibit antioxidant response gene expression in an inducer-dependent manner.

R. Plemper, Julien Sourimant, D. Moir, 2020, ACS infectious diseases.

Current status of small molecule drug development for Ebola virus and other filoviruses.

C. Basler, M. Edwards, 2019, Current opinion in virology.

A high throughput screen identifies benzoquinoline compounds as inhibitors of Ebola virus replication

B. Posner, P. Luthra, C. Basler, 2018, Antiviral research.

Multiple genetic paths including massive gene amplification allow Mycobacterium tuberculosis to overcome loss of ESX-3 secretion system substrates

G. Dougan, Bing Chen, W. Jacobs, 2022, Proceedings of the National Academy of Sciences.

The Marburg virus VP24 protein interacts with Keap1 to activate the cytoprotective antioxidant response pathway.

Wei Xu, Gaya K Amarasinghe, Lauren N. Speller, 2014, Cell reports.

Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation

Jian Jin, Xiaoting Chen, Miriam Merad, 2016, Science.

Structural basis for nuclear import selectivity of pioneer transcription factor SOX2

J. Forwood, C. Basler, S. Nicolis, 2021, Nature Communications.

Structural basis for nuclear import selectivity of pioneer transcription factor SOX2

J. Forwood, C. Basler, S. Nicolis, 2021, Nature Communications.

Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses

J. Forwood, J. Batra, C. Basler, 2018, Nature Communications.

Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1.

Wei Xu, Gaya K Amarasinghe, Rohit V Pappu, 2014, Cell host & microbe.

Interactions of the Nipah Virus P, V, and W Proteins across the STAT Family of Transcription Factors

C. Basler, Timothy R Keiffer, Michael J. Ciancanelli, 2020, mSphere.

Henipavirus W Proteins Interact with 14-3-3 To Modulate Host Gene Expression

J. Forwood, C. Basler, I. Messaoudi, 2020, Journal of Virology.

Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins.

S. Sureshchandra, P. Luthra, Gai Liu, 2016, Cell reports.

Deep Sequencing Identifies Noncanonical Editing of Ebola and Marburg Virus RNAs in Infected Cells

Timothy B. Stockwell, T. Stockwell, M. Mahajan, 2014, mBio.

Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes.

Garrett M. Ginell, P. Luthra, C. Basler, 2018, Cell reports.

The interaction between thymine DNA glycosylase and nuclear receptor coactivator 3 is required for the transcriptional activation of nuclear hormone receptors

G. Domselaar, Jingxin Cao, Xuguang Li, 2009, Molecular and Cellular Biochemistry.

Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism

J. Forwood, C. Basler, M. Edwards, 2023, Viruses.

MERS-CoV ORF4b employs an unusual binding mechanism to target IMPα and block innate immunity

J. Forwood, C. Basler, M. Stewart, 2022, Nature Communications.

Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes.

P. Luthra, C. Basler, D. Leung, 2018, Cell reports.

Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins.

S. Sureshchandra, P. Luthra, Gai Liu, 2016, Cell reports.