Jon Vincelette

发表

Amplified anticoagulant activity of tissue factor-targeted thrombomodulin

D. Light, B. Martin-McNulty, Yi-xin Wang, 2006, Thrombosis and Haemostasis.

A novel P2Y12 adenosine diphosphate receptor antagonist that inhibits platelet aggregation and thrombus formation in rat and dog models

C. Mallari, R. Vergona, W. Dole, 2007, Thrombosis and Haemostasis.

Fasudil , a Rho -

M. Halks-Miller, Xiangru Lu, Q. Feng, 2005 .

Fasudil, a Rho-Kinase Inhibitor, Attenuates Angiotensin II–Induced Abdominal Aortic Aneurysm in Apolipoprotein E–Deficient Mice by Inhibiting Apoptosis and Proteolysis

M. Halks-Miller, Xiangru Lu, Q. Feng, 2005, Circulation.

Intermittent enzyme replacement therapy with recombinant human β-galactosidase prevents neuraminidase 1 deficiency

S. Bunting, Britta Handyside, Sherry Bullens, 2020, Journal of Biological Chemistry.

Intracerebroventricular enzyme replacement therapy with β-galactosidase reverses brain pathologies due to GM1 gangliosidosis in mice

S. Bunting, S. Fong, Britta Handyside, 2019, The Journal of Biological Chemistry.

1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia.

Paul D. Jones, B. Hammock, D. Macintyre, 2011, Bioorganic & medicinal chemistry letters.

Inhibition of soluble epoxide hydrolase attenuates endothelial dysfunction in animal models of diabetes, obesity and hypertension.

D. Macintyre, Sampathkumar Anandan, D. Chen, 2011, European journal of pharmacology.

Delivery of an enzyme-IGFII fusion protein to the mouse brain is therapeutic for mucopolysaccharidosis type IIIB

P. Fitzpatrick, S. Bunting, A. Bagri, 2014, Proceedings of the National Academy of Sciences.

Urokinase-type plasminogen activator deficiency (uPA-KO) prevented carotid artery ligation-induced vascular remodeling in mice.

J. Rutledge, R. Vergona, B. Martin-McNulty, 2007, Translational research : the journal of laboratory and clinical medicine.

Noninvasive measurement of abdominal aortic aneurysms in intact mice by a high-frequency ultrasound imaging system.

R. Vergona, B. Martin-McNulty, M. Sullivan, 2005, Ultrasound in medicine & biology.

Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II): pharmacodynamic and pharmacokinetic characterization.

R. Vergona, W. Dole, J. Morser, 2008, Thrombosis research.

Inhibition of Rho-kinase by fasudil attenuated angiotensin II-induced cardiac hypertrophy in apolipoprotein E deficient mice.

M. Halks-Miller, W. Dole, A. Johns, 2005, European journal of pharmacology.

Antiviral and myocyte protective effects of murine interferon-beta and -{alpha}2 in coxsackievirus B3-induced myocarditis and epicarditis in Balb/c mice.

M. Halks-Miller, E. Croze, T. Yajima, 2007, American journal of physiology. Heart and circulatory physiology.

A novel inhibitor of activated thrombin activatable fibrinolysis inhibitor (TAFIa) – Part II: Enhancement of both exogenous and endogenous fibrinolysis in animal models of thrombosis

R. Vergona, M. Nagashima, W. Dole, 2006, Thrombosis and Haemostasis.

Interaction between mild hypercholesterolemia, HDL-cholesterol levels, and angiotensin II in intimal hyperplasia in mice Published, JLR Papers in Press, December 21, 2005.

J. Rutledge, R. Vergona, D. Wilson, 2006, Journal of Lipid Research.

Inhibition of Rho-Kinase by Hydroxyfasudil Prevents Vasopressin-Induced Myocardial Ischemia in Donryu Rats by Attenuating Coronary Vasoconstriction

R. Vergona, W. Dole, J. Morser, 2005, Pharmacology.

Quantitative Assessment of Neuroinflammation, Myelinogenesis, Demyelination, and Nerve Fiber Regeneration in Immunostained Sciatic Nerves From Twitcher Mice With a Tissue Image Analysis Platform

Guoying Yu, S. Sisó, S. Bunting, 2021, Toxicologic pathology.

Interferon-beta attenuates angiotensin II-accelerated atherosclerosis and vascular remodeling in apolipoprotein E deficient mice.

E. Croze, R. Vergona, S. Velichko, 2008, Atherosclerosis.

Gait analysis in a murine model of collagen-induced arthritis

Yifan Xu, T. Hampton, R. Vergona, 2007, Arthritis research & therapy.

Clearance of Heparan Sulfate and Attenuation of CNS Pathology by Intracerebroventricular BMN 250 in Sanfilippo Type B Mice

P. Fitzpatrick, S. Bunting, Catherine Vitelli, 2017, Molecular therapy. Methods & clinical development.

Intracerebroventricular dosing of N-sulfoglucosamine sulfohydrolase in mucopolysaccharidosis IIIA mice reduces markers of brain lysosomal dysfunction

S. Bunting, S. Fong, Britta Handyside, 2022, The Journal of biological chemistry.

Inhibition of soluble epoxide hydrolase attenuated atherosclerosis, abdominal aortic aneurysm formation and dyslipidemia in apolipoprotein E deficient mice infused with angiotensin II

D. Chen, Ying Cheng, Yi-xin Wang, 2009, Arteriosclerosis, thrombosis, and vascular biology.

A novel inhibitor of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) – Part I: Pharmacological characterization

R. Vergona, M. Nagashima, J. Morser, 2006, Thrombosis and Haemostasis.

Antiviral and myocyte protective effects of murine interferon-beta and -{alpha}2 in coxsackievirus B3-induced myocarditis and epicarditis in Balb/c mice.

M. Halks-Miller, E. Croze, T. Yajima, 2007, American journal of physiology. Heart and circulatory physiology.

Reduced cardiac functional reserve in apolipoprotein E knockout mice.

R. Vergona, B. Martin-McNulty, M. Sullivan, 2006, Translational research : the journal of laboratory and clinical medicine.

Netrin-1 Interrupts Amyloid-β Amplification, Increases sAβPPα in vitro and in vivo, and Improves Cognition in a Mouse Model of Alzheimer's Disease.

D. Bredesen, P. Mehlen, R. Rao, 2016, Journal of Alzheimer's disease : JAD.

Angiotensin II induces histomorphologic features of unstable plaque in a murine model of accelerated atherosclerosis.

M. Halks-Miller, R. Vergona, D. Choy, 2006, Journal of vascular surgery.

Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B

A. Shaywitz, P. Fitzpatrick, S. Bunting, 2020, Drug Delivery and Translational Research.

P-selectin-targeting of the fibrin selective thrombolytic Desmodus rotundus salivary plasminogen activator α1

Junliang Pan, W. Dole, J. Morser, 2004, Thrombosis and Haemostasis.

A. Shaywitz, P. Fitzpatrick, S. Bunting, 2020, Drug Delivery and Translational Research.

Histologic characterization of the progression of central nervous system pathology in the mucopolysaccharidosis IIIB (MPS IIIB, Sanfilippo syndrome type B) mouse model and bio-distribution and efficacy of the intracerebroventricular enzyme replacement therapy, BMN 250

P. Fitzpatrick, S. Bunting, A. Bagri, 2016 .

Intermittent enzyme replacement therapy prevents Neu1 deficiency

S. Bunting, Britta Handyside, V. Agrawal, 2020, The Journal of Biological Chemistry.

Intermittent enzyme replacement therapy with recombinant human b -galactosidase prevents neuraminidase 1 deficiency

Britta Handyside, Jon Vincelette, G. Yogalingam, 2020 .

S. Cases, Sampathkumar Anandan, J. Waszczuk, 2011, Bioorganic & medicinal chemistry letters.