A. Zanin-Zhorov

发表

Functional anatomy of T cell activation and synapse formation.

Michael Loran Dustin, G. Victora, David R Fooksman, 2010, Annual review of immunology.

of T Cell Activation and Synapse Formation

Michael Loran Dustin, G. Victora, David R Fooksman, 2010 .

PKC-θ function at the immunological synapse: prospects for therapeutic targeting.

Michael Loran Dustin, B. Blazar, A. Zanin-Zhorov, 2011, Trends in immunology.

Heat Shock Protein 60 Activates Cytokine-Associated Negative Regulator Suppressor of Cytokine Signaling 3 in T Cells: Effects on Signaling, Chemotaxis, and Inflammation1

I. Cohen, Shoham Shivtiel, T. Lapidot, 2005, The Journal of Immunology.

Inflammation Cells : Effects on Signaling , Chemotaxis , and Suppressor of Cytokine Signaling 3 in T Cytokine-Associated Negative Regulator Heat Shock Protein 60 Activates

I. Cohen, Shoham Shivtiel, T. Lapidot, 2005 .

Halofuginone inhibits NF‐κB and p38 MAPK in activated T cells

A. Nagler, M. Leiba, L. Cahalon, 2006 .

The selective ROCK2 inhibitor KD025 reduces IL‐17 secretion in human peripheral blood mononuclear cells independent of IL‐1 and IL‐6

J. Weiss, C. Dinarello, Jingya Zhang, 2018, European journal of immunology.

Heat Shock Protein 60 Inhibits Th1-Mediated Hepatitis Model via Innate Regulation of Th1/Th2 Transcription Factors and Cytokines1

I. Cohen, R. Hershkoviz, O. Lider, 2005, The Journal of Immunology.

Human in vitro-induced regulatory T cells display Dlgh1 dependent and PKC-θ restrained suppressive activity

Sudha Kumari, Michael Loran Dustin, M. MacMillan, 2017, Scientific Reports.

ROCK2 Inhibition With Belumosudil (KD025) for the Treatment of Chronic Graft-Versus-Host Disease

J. Weiss, Stephanie J. Lee, O. Schueller, 2021, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Signaling via TLR2 and TLR4 Directly Down-Regulates T Cell Effector Functions: The Regulatory Face of Danger Signals

I. Cohen, A. Zanin-Zhorov, 2013, Front. Immunol..

Transcription Factors and Hepatitis Model via Innate Regulation of Heat Shock Protein 60 Inhibits Th1-Mediated

I. Cohen, R. Hershkoviz, O. Lider, 2005 .

Cytokines Th 1 / Th 2 Transcription Factors and Hepatitis Model via Innate Regulation of Heat Shock Protein 60 Inhibits Th 1-Mediated

I. Cohen, R. Hershkoviz, O. Lider, 2005 .

T cells respond to heat shock protein 60 via TLR2: activation of adhesion and inhibition of chemokine receptors

I. Cohen, S. Franitza, G. Nussbaum, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cutting Edge: T Cells Respond to Lipopolysaccharide Innately via TLR4 Signaling1

M. Pevsner-Fischer, I. Cohen, L. Cahalon, 2007, The Journal of Immunology.

SignalingLipopolysaccharide Innately via TLR4 Cutting Edge: T Cells Respond to

M. Pevsner-Fischer, I. Cohen, L. Cahalon, 2022 .

Heat shock protein 60 enhances CD4+CD25+ regulatory T cell function via innate TLR2 signaling.

I. Cohen, L. Cahalon, O. Lider, 2018, The Journal of clinical investigation.

Fibronectin-Associated Fas Ligand Rapidly Induces Opposing and Time-Dependent Effects on the Activation and Apoptosis of T Cells 1

R. Hershkoviz, L. Cahalon, O. Lider, 2003, The Journal of Immunology.

Retraction

Irun R. Cohen, S. Franitza, John Yu, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Toll-like receptors and their ligands control mesenchymal stem cell functions.

M. Pevsner-Fischer, I. Cohen, S. Cohen, 2007, Blood.

Peptide p277 of HSP60 signals T cells: inhibition of inflammatory chemotaxis.

Irun R Cohen, I. Cohen, F. Quintana, 2006, International immunology.

The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice

Zhinan Yin, Jian Tao, S. Abramson, 2011, Science.

Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function

Sudha Kumari, S. Abramson, Michael Loran Dustin, 2012, Proceedings of the National Academy of Sciences.

Protein Kinase C-θ Mediates Negative Feedback on Regulatory T Cell Function

Sudha Kumari, S. Abramson, Michael Loran Dustin, 2010, Science.

ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings

J. Weiss, B. Blazar, R. Flynn, 2016, Science Signaling.

Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism

J. Weiss, Michael Loran Dustin, Chuan-ju Liu, 2014, Proceedings of the National Academy of Sciences.

Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.

J. Weiss, J. Ritz, D. Munn, 2016, Blood.

ROCK2, but not ROCK1 interacts with phosphorylated STAT3 and co-occupies TH17/TFH gene promoters in TH17-activated human T cells

J. Weiss, Jingya Zhang, A. Zanin-Zhorov, 2018, Scientific Reports.

Initial Results of KD025-208: A Phase 2a Open-Label Clinical Trial of KD025 for Steroid-Dependent Chronic Graft Versus Host Disease (cGVHD)

Stephanie J. Lee, J. Ryan, O. Schueller, 2018 .

ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis

W. Schroder, G. Hill, K. Irvine, 2021, JHEP Reports.

Heat shock protein 60 enhances CD4+ CD25+ regulatory T cell function via innate TLR2 signaling.

Guy Tal, Irun R Cohen, Raanan Margalit, 2006, The Journal of clinical investigation.

Cutting Edge: Selective Oral ROCK2 Inhibitor Reduces Clinical Scores in Patients with Psoriasis Vulgaris and Normalizes Skin Pathology via Concurrent Regulation of IL-17 and IL-10

Wei Chen, Mark Lebwohl, James G Krueger, 2017, The Journal of Immunology.

HSP60 and the regulation of inflammation: Physiological and pathological

I. Cohen, F. Quintana, G. Nussbaum, 2003 .

Isoform-specific targeting of ROCK proteins in immune cells

B. Blazar, R. Flynn, A. Zanin-Zhorov, 2016, Small GTPases.

ROCK2, a critical regulator of immune modulation and fibrosis has emerged as a therapeutic target in chronic graft-versus-host disease.

B. Blazar, A. Zanin-Zhorov, 2021, Clinical immunology.

Heat Shock Protein 60 Activates B Cells via the TLR4-MyD88 Pathway1

Irun R. Cohen, Michal Cohen-Sfady, M. Pevsner-Fischer, 2005, The Journal of Immunology.

HSP60: A Pleiotropic Immune Signal

I. Cohen, A. Zanin-Zhorov, 2007 .

Amendment history : Retraction ( May 2018 ) Heat shock protein 60 enhances CD 4 + CD 25 + regulatory T cell function via innate TLR 2 signaling

I. Cohen, L. Cahalon, O. Lider, 2018 .

ROCKing cytokine secretion balance in human T cells.

A. Zanin-Zhorov, S. Waksal, 2015, Cytokine.

Polyhydroxylated fatty alcohols derived from avocado suppress inflammatory response and provide non-sunscreen protection against UV-induced damage in skin cells

A. Schroeder, M. Tarshis, A. Ingber, 2011, Archives of Dermatological Research.

Heat shock protein 60 enhances CD4+ CD25+ regulatory T cell function via innate TLR2 signaling.

I. Cohen, L. Cahalon, O. Lider, 2006, The Journal of clinical investigation.

KD025-208: A Phase 2a Study of KD025 for Patients with Chronic Graft Versus Host Disease (cGVHD) — Pharmacodynamics and Updated Results

J. Weiss, Stephanie J. Lee, O. Schueller, 2018, Blood.