T. Sullivan

Design of synthetic oligoribonucleotide-based agonists of Toll-like receptor 3 and their immune response profiles in vitro and in vivo.

Dong Yu, S. Agrawal, N. La Monica, 2013, Organic & biomolecular chemistry.

An antibody to IP-10 is a potent antagonist of cell migration in vitro and in vivo and does not affect disease in several animal models of inflammation

S. Steavenson, D. Brankow, T. Juan, 2009, Autoimmunity.

IMO-8400, a toll-like receptor 7, 8, and 9 antagonist, demonstrates clinical activity in a phase 2a, randomized, placebo-controlled trial in patients with moderate-to-severe plaque psoriasis.

R. Arbeit, E. Prens, H. Thio, 2017, Clinical immunology.

Design, synthesis and biological evaluation of novel antagonist compounds of Toll-like receptors 7, 8 and 9

Dong Yu, S. Agrawal, N. La Monica, 2013, Nucleic acids research.

Impact of Secondary Structure of Toll-Like Receptor 9 Agonists on Interferon Alpha Induction

Dong Yu, S. Agrawal, E. Kandimalla, 2008, Antimicrobial Agents and Chemotherapy.

Immunomodulatory oligonucleotides containing a cytosine-phosphate-2'-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonists.

Dong Yu, S. Agrawal, E. Kandimalla, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Stabilized immune modulatory RNA compounds as agonists of Toll-like receptors 7 and 8

Dong Yu, S. Agrawal, T. Lan, 2007, Proceedings of the National Academy of Sciences.

Suppression of Molecular Inflammatory Pathways by Toll-Like Receptor 7, 8, and 9 Antagonists in a Model of IL-23-Induced Skin Inflammation

R. Arbeit, M. Suárez-Fariñas, J. Krueger, 2013, PloS one.

P3-112: Initial phase 1 results of gemcitabine, carboplatin and IMO-2055, a toll like receptor 9 (TLR9) agonist, in patients (pts) with advanced solid tumors

R. Karr, J. Marshall, S. Malik, 2007 .

Application of XIAP Antisense to Cancer and Other Proliferative Disorders: Development of AEG35156/ GEM®640

S. Agrawal, J. Gillard, P. Winocour, 2005, Annals of the New York Academy of Sciences.