Seung-Joo Lee

发表

Primer release is the rate-limiting event in lagging-strand synthesis mediated by the T7 replisome

C. Richardson, Alfredo J. Hernandez, Seung-Joo Lee, 2016, Proceedings of the National Academy of Sciences.

DNA recognition by the DNA primase of bacteriophage T7: a structure-function study of the zinc-binding domain.

C. Richardson, B. Akabayov, Sabine R. Akabayov, 2009, Biochemistry.

Hydrophobic Residue in Escherichia coli Thioredoxin Critical for the Processivity of T7 DNA Polymerase.

C. Richardson, N. Q. Tran, Seung-Joo Lee, 2018, Biochemistry.

Binding Affinities among DNA Helicase-Primase, DNA Polymerase, and Replication Intermediates in the Replisome of Bacteriophage T7*

Jia Cao, C. Richardson, Huidong Zhang, 2015, The Journal of Biological Chemistry.

Thioredoxin, the Processivity Factor, Sequesters an Exposed Cysteine in the Thumb Domain of Bacteriophage T7 DNA Polymerase*

C. Richardson, B. Akabayov, N. Q. Tran, 2012, The Journal of Biological Chemistry.

Heterohexamer of 56- and 63-kDa Gene 4 Helicase-Primase of Bacteriophage T7 in DNA Replication*

C. Richardson, A. W. Kulczyk, Huidong Zhang, 2012, The Journal of Biological Chemistry.

Gene 5.5 protein of bacteriophage T7 in complex with Escherichia coli nucleoid protein H-NS and transfer RNA masks transfer RNA priming in T7 DNA replication

C. Richardson, E. Wang, Seung-Joo Lee, 2012, Proceedings of the National Academy of Sciences.

Helicase-DNA polymerase interaction is critical to initiate leading-strand DNA synthesis

C. Richardson, S. Tabor, N. Q. Tran, 2011, Proceedings of the National Academy of Sciences.

Bypass of a Nick by the Replisome of Bacteriophage T7*

C. Richardson, Seung-Joo Lee, B. Zhu, 2011, The Journal of Biological Chemistry.

Choreography of bacteriophage T7 DNA replication.

C. Richardson, Seung-Joo Lee, 2011, Current opinion in chemical biology.

Exchange of DNA polymerases at the replication fork of bacteriophage T7

S. Hamdan, Masateru Takahashi, C. Richardson, 2007, Proceedings of the National Academy of Sciences.

Essential Residues in the C Terminus of the Bacteriophage T7 Gene 2.5 Single-stranded DNA-binding Protein*

S. Hamdan, B. Marintcheva, C. Richardson, 2006, Journal of Biological Chemistry.

An in Trans Interaction at the Interface of the Helicase and Primase Domains of the Hexameric Gene 4 Protein of Bacteriophage T7 Modulates Their Activities*

C. Richardson, Seung-Joo Lee, B. Zhu, 2009, The Journal of Biological Chemistry.

Interaction of adjacent primase domains within the hexameric gene 4 helicase-primase of bacteriophage T7

C. Richardson, Seung-Joo Lee, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Residues located in the primase domain of the bacteriophage T7 primase-helicase are essential for loading the hexameric complex onto DNA

J. Griffith, C. Richardson, Alfredo J. Hernandez, 2022, The Journal of biological chemistry.

The Roles of Tryptophans in Primer Synthesis by the DNA Primase of Bacteriophage T7*

C. Richardson, Huidong Zhang, Seung-Joo Lee, 2012, The Journal of Biological Chemistry.

Communication between subunits critical to DNA binding by hexameric helicase of bacteriophage T7

C. Richardson, U. Qimron, Seung-Joo Lee, 2008, Proceedings of the National Academy of Sciences.

NMR 1H,13C, 15N resonance assignment of the G12C mutant of human K-Ras bound to GppNHp

Alok K. Sharma, A. C. Rigby, S. Townson, 2019, Biomolecular NMR assignments.

Zinc-binding Domain of the Bacteriophage T7 DNA Primase Modulates Binding to the DNA Template*

C. Richardson, B. Akabayov, Seung-Joo Lee, 2012, The Journal of Biological Chemistry.

Directed evolution of adenine base editors with increased activity and therapeutic application

Jonathan Yen, Nicole M. Gaudelli, Jason M. Gehrke, 2020, Nature Biotechnology.

A novel nucleotide kinase encoded by gene 1.7 of bacteriophage T7

C. Richardson, S. Tabor, Seung-Joo Lee, 2010, Molecular microbiology.

Essential protein interactions within the replisome regulate DNA replication

C. Richardson, Huidong Zhang, Seung-Joo Lee, 2011, Cell cycle.

Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System

G. Verdine, R. Sung, Seung-Joo Lee, 2019, Research.

A unique loop in T7 DNA polymerase mediates the binding of helicase-primase, DNA binding protein, and processivity factor.

Boriana Marintcheva, Seung-Joo Lee, S. Hamdan, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Exceptionally high-affinity Ras binders that remodel its effector domain

G. Verdine, Seung-Joo Lee, S. Shim, 2017, The Journal of Biological Chemistry.

Rescue of Bacteriophage T7 DNA Polymerase of Low Processivity by Suppressor Mutations Affecting Gene 3 Endonuclease

C. Richardson, S. Tabor, Seung-Joo Lee, 2009, Journal of Virology.

Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity

Nicole M. Gaudelli, Luis A. Barrera, H. Rees, 2020, Nature Communications.

Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity

Nicole M. Gaudelli, Luis A. Barrera, H. Rees, 2020, Nature Communications.

Acidic Residues in the Nucleotide-binding Site of the Bacteriophage T7 DNA Primase*

C. Richardson, Seung-Joo Lee, 2005, Journal of Biological Chemistry.

Flap Endonuclease Activity of Gene 6 Exonuclease of Bacteriophage T7*

C. Richardson, S. Tabor, Seung-Joo Lee, 2014, The Journal of Biological Chemistry.

Possible roles in RNA primer removal, recombination and host DNA breakdown

C. Richardson, S. Tabor, Seung-Joo Lee, 2014 .

Primer initiation and extension by T7 DNA primase

S. Hamdan, C. Richardson, U. Qimron, 2006, The EMBO journal.

Flap endonuclease of bacteriophage T7

C. Richardson, S. Tabor, Seung-Joo Lee, 2014, Bacteriophage.

Essential Lysine Residues in the RNA Polymerase Domain of the Gene 4 Primase-Helicase of Bacteriophage T7*

S. Lee, C. Richardson, Seung-Joo Lee, 2001, The Journal of Biological Chemistry.

NMR 1H,13C, 15N backbone and 13C side chain resonance assignment of the G12C mutant of human K-Ras bound to GDP

Alok K. Sharma, A. C. Rigby, S. Townson, 2018, Biomolecular NMR assignments.

Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface

Daniel W. Udwary, Andrew T Rajczewski, R. Klausner, 2020, Proceedings of the National Academy of Sciences.

Catalytically inactive T7 DNA polymerase imposes a lethal replication roadblock

J. Loparo, C. Richardson, Alfredo J. Hernandez, 2020, The Journal of Biological Chemistry.

The C-terminal Residues of Bacteriophage T7 Gene 4 Helicase-Primase Coordinate Helicase and DNA Polymerase Activities*

Boriana Marintcheva, Seung-Joo Lee, S. Hamdan, 2006, Journal of Biological Chemistry.

Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase*

G. Verdine, Seung-Joo Lee, Lan Wang, 2015, The Journal of Biological Chemistry.

Molecular Basis for Recognition of Nucleoside Triphosphate by Gene 4 Helicase of Bacteriophage T7*

C. Richardson, Seung-Joo Lee, 2010, The Journal of Biological Chemistry.

The Linker Region between the Helicase and Primase Domains of the Gene 4 Protein of Bacteriophage T7

C. Richardson, Seung-Joo Lee, 2004, Journal of Biological Chemistry.

Conformational dynamics of bacteriophage T7 DNA polymerase and its processivity factor, Escherichia coli thioredoxin

C. Richardson, S. Tabor, A. W. Kulczyk, 2010, Proceedings of the National Academy of Sciences.

Direct role for the RNA polymerase domain of T7 primase in primer delivery

C. Richardson, Seung-Joo Lee, B. Zhu, 2010, Proceedings of the National Academy of Sciences.

An Interaction between DNA Polymerase and Helicase Is Essential for the High Processivity of the Bacteriophage T7 Replisome*

S. Berkowitz, C. Richardson, M. Bostina, 2012, The Journal of Biological Chemistry.

Impact of macromolecular crowding on DNA replication

Charles C. Richardson, Gerhard Wagner, Barak Akabayov, 2012, Nature Communications.

Mechanism of sequence-specific template binding by the DNA primase of bacteriophage T7

S. Hamdan, C. Richardson, Seung-Joo Lee, 2010, Nucleic acids research.

Regulation of T7 gp2.5 binding dynamics by its C-terminal tail, template conformation and sequence

E. Peterman, A. V. van Oijen, G. Wuite, 2023, Nucleic acids research.

The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase

M. Karplus, K. Nam, G. Verdine, 2020, Nature Communications.