S. Keysar

发表

Combined hedgehog and epidermal growth factor receptor (EGFR) inhibition in a direct patient tumor model (DPTM) of head and neck squamous cell cancer (HNSCC).

A. Jimeno, A. Tan, Ryan T Anderson, 2010 .

Mutant spectra of irradiated CHO AL cells determined with multiple markers analyzed by flow cytometry.

M. Fox, C. T. French, S. Keysar, 2007, Mutation research.

Caveolin-1 and Sox-2 are predictive biomarkers of cetuximab response in head and neck cancer

G. Mills, N. Krogan, A. Olshen, 2021, JCI insight.

More than Markers: Biological Significance of Cancer Stem Cell-Defining Molecules

A. Jimeno, S. Keysar, Stephen B. Keysar, 2010, Molecular Cancer Therapeutics.

Epidermal growth factor receptor signaling in precancerous keratinocytes promotes neighboring head and neck cancer squamous cell carcinoma cancer stem cell‐like properties and phosphoinositide 3‐kinase inhibitor insensitivity

A. Jimeno, C. Young, S. Keysar, 2022, Molecular carcinogenesis.

Dual use of hematopoietic and mesenchymal stem cells enhances engraftment and immune cell trafficking in an allogeneic humanized mouse model of head and neck cancer

Brian C. Jackson, A. Jimeno, B. Jackson, 2018, Molecular carcinogenesis.

Comparison of the mutagenic potential of 17 physical and chemical agents analyzed by the flow cytometry mutation assay.

C. Lim, M. Fox, C. T. French, 2006, Mutation research.

Title : Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer

M. Lucia, A. Jimeno, A. Thorburn, 2013 .

Procedure for Horizontal Transfer of Patient-Derived Xenograft Tumors to Eliminate Corynebacterium bovis.

T. Pitts, J. Arcaroli, S. Bagby, 2017, Journal of the American Association for Laboratory Animal Science : JAALAS.

EMS mutant spectra generated by multi-parameter flow cytometry.

M. Fox, S. Keysar, Stephen B. Keysar, 2009, Mutation research.

Kinetics of CHO AL mutant expression after treatment with γ radiation, EMS, and asbestos

M. Fox, S. Keysar, Stephen B. Keysar, 2009, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases.

A. Jimeno, U. Rix, M. Varella‐Garcia, 2017, Cancer research.

Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2

Brian C. Jackson, A. Jimeno, L. Wakefield, 2017, Journal of the National Cancer Institute.

MAPKAPK2 (MK2) inhibition mediates radiation-induced inflammatory cytokine production and tumor growth in head and neck squamous cell carcinoma

A. Jimeno, D. McCance, M. Ozbun, 2019, Oncogene.

XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer

A. Jimeno, M. Varella‐Garcia, A. Tan, 2015, Oncogene.

An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101.

Dara L Aisner, Antonio Jimeno, P. Stephens, 2015, Cancer discovery.

Salivary Gland Cancer Patient-Derived Xenografts Enable Characterization of Cancer Stem Cells and New Gene Events Associated with Tumor Progression

Brian C. Jackson, A. Jimeno, M. Varella‐Garcia, 2018, Clinical Cancer Research.

Inter‐ and intra‐tumor heterogeneity of SMAD4 loss in head and neck squamous cell carcinomas

A. Jimeno, M. Varella‐Garcia, S. Karam, 2019, Molecular carcinogenesis.

Phase I Study of Oral Rigosertib (ON 01910.Na), a Dual Inhibitor of the PI3K and Plk1 Pathways, in Adult Patients with Advanced Solid Malignancies

A. Jimeno, E. Lam, M. Varella‐Garcia, 2014, Clinical Cancer Research.

The Dual Pathway Inhibitor Rigosertib Is Effective in Direct Patient Tumor Xenografts of Head and Neck Squamous Cell Carcinomas

A. Jimeno, M. Varella‐Garcia, A. Tan, 2013, Molecular Cancer Therapeutics.

Small Molecule Therapeutics The Dual Pathway Inhibitor Rigosertib Is Effective in Direct Patient Tumor Xenografts of Head and Neck Squamous Cell Carcinomas

A. Jimeno, M. Varella‐Garcia, A. Tan, 2013 .

Title : The dual pathway inhibitor rigosertib is effective in direct-patient tumor xenografts of head and neck squamous cell carcinomas

A. Jimeno, M. Varella‐Garcia, A. Tan, 2013 .

Wnt signaling dynamics in head and neck squamous cell cancer tumor‐stroma interactions

Brian C. Jackson, A. Jimeno, J. Morton, 2018, Molecular carcinogenesis.

A pilot study of cetuximab and the hedgehog inhibitor IPI-926 in recurrent/metastatic head and neck squamous cell carcinoma.

A. Jimeno, D. Gao, A. Tan, 2016, Oral oncology.

Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer.

M. Lucia, A. Jimeno, A. Thorburn, 2013, Cancer research.

Hedgehog signaling drives radioresistance and stroma-driven tumor repopulation in head and neck squamous cancers.

A. Jimeno, D. Raben, M. Glogowska, 2014, Cancer research.

A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins

A. Jimeno, F. Hirsch, M. Varella‐Garcia, 2013, Molecular oncology.

An Inducible TGF-β2-TGFβR Pathway Modulates the Sensitivity of HNSCC Cells to Tyrosine Kinase Inhibitors Targeting Dominant Receptor Tyrosine Kinases

Katherine R. Singleton, A. Jimeno, Jihye Kim, 2015, PloS one.

Ephrin‐B2 overexpression predicts for poor prognosis and response to therapy in solid tumors

A. Jimeno, S. Karam, J. Califano, 2017, Molecular carcinogenesis.

A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer

A. Jimeno, M. Varella‐Garcia, D. Gao, 2016, International journal of cancer.

DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E2 Growth Factor Release in Response to Low and High LET Ionizing Radiation

N. Sharma, M. Durante, A. Jimeno, 2015, Front. Oncol..

Epithelial stem cell mutations that promote squamous cell carcinoma metastasis.

A. Jimeno, D. Roop, L. Dionne, 2013, The Journal of clinical investigation.

Cancer Cell CD44 Mediates Macrophage/Monocyte-Driven Regulation of Head and Neck Cancer Stem Cells

A. Jimeno, T. Lyons, Hongmei Zhou, 2020, Cancer Research.

Inhibiting translation elongation with SVC112 suppresses cancer stem cells and inhibits growth in head and neck squamous carcinoma.

Brian C. Jackson, A. Jimeno, A. Tan, 2020, Cancer research.

Enhancing radiosensitization in EphB4 receptor-expressing Head and Neck Squamous Cell Carcinomas

A. Jimeno, S. Karam, D. Raben, 2016, Scientific Reports.

Studying Immunotherapy Resistance in a Melanoma Autologous Humanized Mouse Xenograft

A. Jimeno, D. Gao, A. Tan, 2020, Molecular Cancer Research.

Abstract 652: PI3K inhibition combined with either cetuximab or docetaxel in a direct patient tumor model of HPV-positive and negative head and neck cancers

A. Jimeno, D. Sehrt, D. Bowles, 2011 .