Xiaoxiao Yang

发表

Nanoparticle encapsulation of non-genotoxic p53 activator Inauhzin-C for improved therapeutic efficacy

J. Paruch, Hua Lu, Binghe Wang, 2021, Theranostics.

"CO in a pill": Towards oral delivery of carbon monoxide for therapeutic applications.

Minjia Wang, Binghe Wang, Chalet Tan, 2021, Journal of controlled release : official journal of the Controlled Release Society.

Activated Charcoal Dispersion of Carbon Monoxide Prodrugs for Oral Delivery of CO in a Pill.

Binghe Wang, Minjia Wang, Chalet Tan, 2022, International journal of pharmaceutics.

Click and Release: A High-Content Bioorthogonal Prodrug with Multiple Outputs.

B. Wang, Xiaoxiao Yang, Bingchen Yu, 2019, Organic letters.

Nature's marvels endowed in gaseous molecules I: Carbon monoxide and its physiological and therapeutic roles

B. Wang, Xiaoxiao Yang, Wen Lu, 2020, Acta pharmaceutica Sinica. B.

Click, release, and fluoresce: In-vivo generation of CO with concomitant synthesis of a fluorescent reporter.

Binghe Wang, Xiaoxiao Yang, X. Ji, 2021, Bioorganic & medicinal chemistry.

Organic carbon monoxide prodrug, BW-CO-111, in protection against chemically-induced gastric mucosal damage

B. Wang, T. Brzozowski, Xiaoxiao Yang, 2020, Acta pharmaceutica Sinica. B.

Nitro reduction-based fluorescent probes for carbon monoxide require reactivity involving a ruthenium carbonyl moiety.

B. Wang, Xiaoxiao Yang, Zhengnan Yuan, 2020, Chemical communications.

Carbon Monoxide Signaling: Examining Its Engagement with Various Molecular Targets in the Context of Binding Affinity, Concentration, and Biologic Response

Binghe Wang, Xiaoxiao Yang, Zhengnan Yuan, 2022, Pharmacological Reviews.

Redox and catalase-like activities of four widely used carbon monoxide releasing molecules (CO-RMs)

Binghe Wang, Xiaoxiao Yang, Zhengnan Yuan, 2021, Chemical science.

Adapting decarbonylation chemistry for the development of prodrugs capable of in vivo delivery of carbon monoxide utilizing sweeteners as carrier molecules

M. D. de Caestecker, L. Otterbein, Binghe Wang, 2021, Chemical science.

Inducing apoptosis through upregulation of p53: structure–activity exploration of anthraquinone analogs

B. Wang, A. A. Agbowuro, R. Tripathi, 2020, Medicinal Chemistry Research.

Chemical Reactivities of Two Widely Used Ruthenium-Based CO-Releasing Molecules with a Range of Biologically Important Reagents and Molecules.

Binghe Wang, R. Tripathi, Xiaoxiao Yang, 2021, Analytical chemistry.

Restoring and Enhancing the Potency of Existing Antibiotics against Drug-Resistant Gram-Negative Bacteria through the Development of Potent Small-Molecule Adjuvants.

J. Gumbart, Arvind Kumar, D. Boykin, 2022, ACS infectious diseases.

Prodrugs of Persulfides, SO2, and CS2: Important Tools for Studying Sulfur Signaling at Various Oxidation States.

Binghe Wang, Xiaoxiao Yang, Bingchen Yu, 2020, Antioxidants & redox signaling.

Mutual leveraging of proximity effects and click chemistry in chemical biology

Binghe Wang, Xiaoxiao Yang, Xingyue Ji, 2022, Medicinal research reviews.

Upregulation of p53 through induction of MDM2 degradation: improved potency through the introduction of an alkylketone sidechain on the anthraquinone core

Binghe Wang, R. Tripathi, Xiaoxiao Yang, 2022, Journal of enzyme inhibition and medicinal chemistry.

Esterase-Sensitive Glutathione Persulfide Donor.

B. Wang, Siming Wang, Xiaoxiao Yang, 2018, Organic letters.

Upregulation of p53 through induction of MDM2 degradation: Amino acid prodrugs of anthraquinone analogs.

B. Wang, Xiaoxiao Yang, Yueqin Zheng, 2019, Bioorganic & medicinal chemistry letters.

Anticancer strategies by upregulating p53 through inhibition of its ubiquitination by MDM2

B. Wang, A. A. Agbowuro, Xiaoxiao Yang, 2020, Medicinal Chemistry Research.

De Novo Construction of Fluorophores via CO Insertion-Initiated Lactamization: A Chemical Strategy toward Highly Sensitive and Highly Selective Turn-On Fluorescent Probes for Carbon Monoxide.

Binghe Wang, Minjia Wang, R. Tripathi, 2022, Journal of the American Chemical Society.

Carbon Monoxide Signaling and Soluble Guanylyl Cyclase: Facts, Myths, and Intriguing Possibilities.

Binghe Wang, Xiaoxiao Yang, Wen Lu, 2022, Biochemical pharmacology.

CO as a therapeutic agent: discovery and delivery forms.

B. Wang, Xiaoxiao Yang, Wen Lu, 2020, Chinese journal of natural medicines.

Carbon monoxide: An emerging therapy for acute kidney injury

M. D. de Caestecker, L. Otterbein, B. Wang, 2019, Medicinal research reviews.

Toward “CO in a Pill”: Silica-Immobilized Organic CO Prodrugs for Studying the Feasibility of Systemic Delivery of CO via In Situ Gastrointestinal CO Release

Binghe Wang, Minjia Wang, Chalet Tan, 2023, Molecular pharmaceutics.

Upregulation of p53 through induction of MDM2 degradation: Anthraquinone analogs.

L. Gu, Mu-xiang Zhou, B. Wang, 2019, Bioorganic & medicinal chemistry.

Carbon Monoxide as a Therapeutic for Airway Diseases: Contrast and Comparison of Various CO Delivery Modalities.

S. Ryter, Binghe Wang, R. Tripathi, 2021, Current topics in medicinal chemistry.

Making smart drugs smarter: The importance of linker chemistry in targeted drug delivery

B. Wang, Xiaoxiao Yang, Bingchen Yu, 2020, Medicinal research reviews.

Plight of CORMs: the unreliability of four commercially available CO-releasing molecules, CORM-2, CORM-3, CORM-A1, and CORM-401, in studying CO biology.

Binghe Wang, Xiaoxiao Yang, N. Bauer, 2023, Biochemical pharmacology.

Sensing a CO-Releasing Molecule (CORM) Does Not Equate to Sensing CO: The Case of DPHP and CORM-3

Binghe Wang, Xiaoxiao Yang, Dongning Liu, 2023, Analytical chemistry.

Prodrugs of sulfide and persulfide species: Implications in their different pharmacological activities.

Binghe Wang, Xiaoxiao Yang, Bingchen Yu, 2023, Current opinion in chemical biology.

Towards "CO in a pill": Pharmacokinetic studies of carbon monoxide prodrugs in mice.

B. Wang, Minjia Wang, Yingzhe Wang, 2020, Journal of controlled release : official journal of the Controlled Release Society.

On the Question of Uncatalyzed CO Insertion into a Hydrazone Double Bond: A Comparative Study Using Different CO Sources and Substrates

Xiaoxiao Yang, Wen Lu, Dongning Liu, 2024, The Journal of organic chemistry.