Dan Huang

发表

Macrophage-targeted Isoniazid-selenium nanoparticles promote innate immunity, inducing synergistic antimicrobial and bactericidal destructions of tuberculosis bacilli.

Jiye Cai, G. Zeng, H. Shen, 2019, Angewandte Chemie.

Macrophage‐Targeted Isoniazid–Selenium Nanoparticles Promote Antimicrobial Immunity and Synergize Bactericidal Destruction of Tuberculosis Bacilli

Jiye Cai, G. Zeng, H. Shen, 2019 .

Severe tuberculosis induces unbalanced up-regulation of gene networks and overexpression of IL-22, MIP-1alpha, CCL27, IP-10, CCR4, CCR5, CXCR3, PD1, PDL2, IL-3, IFN-beta, TIM1, and TLR2 but low antigen-specific cellular responses.

B. Haynes, W. Jacobs, N. Letvin, 2008, The Journal of infectious diseases.

Efficacy and safety of live attenuated persistent and rapidly cleared Mycobacterium tuberculosis vaccine candidates in non-human primates.

B. Haynes, Bing Chen, W. Jacobs, 2009, Vaccine.

Differentiation, distribution and {gamma}{delta} T cell-driven regulation of IL-22-producing T cells in tuberculosis

G. Zeng, Zheng W. Chen, Crystal Y. Chen, 2010 .

Differentiation, Distribution and γδ T Cell-Driven Regulation of IL-22-Producing T Cells in Tuberculosis

G. Zeng, Zheng W. Chen, Crystal Y. Chen, 2010, PLoS pathogens.

Membrane-Bound IL-22 after De Novo Production in Tuberculosis and Anti-Mycobacterium tuberculosis Effector Function of IL-22+ CD4+ T Cells

G. Zeng, Zheng W. Chen, Crystal Y. Chen, 2011, The Journal of Immunology.

Tim-3-Expressing CD4+ and CD8+ T Cells in Human Tuberculosis (TB) Exhibit Polarized Effector Memory Phenotypes and Stronger Anti-TB Effector Functions

Boping Zhou, Jianbo Chen, Jiye Cai, 2012, PLoS pathogens.

Cell-Based High-Throughput Screening Assay Identifies 2',2'-Difluoro-2'-deoxycytidine Gemcitabine as a Potential Antipoliovirus Agent.

M. Vignuzzi, H. Shen, Lijun Rong, 2017, ACS infectious diseases.

Selected prfA* Mutations in Recombinant Attenuated Listeria monocytogenes Strains Augment Expression of Foreign Immunogens and Enhance Vaccine-Elicited Humoral and Cellular Immune Responses

Jianbo Chen, N. Freitag, Lijun Rong, 2008, Infection and Immunity.

Intranasal Vaccination with the Recombinant Listeria monocytogenes ΔactA prfA* Mutant Elicits Robust Systemic and Pulmonary Cellular Responses and Secretory Mucosal IgA

B. Haynes, Jianbo Chen, N. Letvin, 2011, Clinical and Vaccine Immunology.

Adoptive Transfer of Phosphoantigen-Specific γδ T Cell Subset Attenuates Mycobacterium tuberculosis Infection in Nonhuman Primates

W. Jacobs, Lixia Qian, Zhuoran Zhang, 2017, The Journal of Immunology.

Tuberculous pleurisy drives marked effector responses of γδ, CD4+, and CD8+ T cell subpopulations in humans

H. Shen, Junfa Xu, Zheng W. Chen, 2015, Journal of leukocyte biology.

Multidrug-resistant tuberculosis (MDR-TB) strain infection in macaques results in high bacilli burdens in airways, driving broad innate/adaptive immune responses

H. Shen, Wenzhe Ho, Zhuoran Zhang, 2018, Emerging Microbes & Infections.

current as T Cells + CD 4 + of IL-22 Effector Function Mycobacterium tuberculosis Production in Tuberculosis and Anti-Membrane-Bound IL-22 after De Novo

Richard C. Wang, Dan Huang, S. Yao, 2011 .

NSOM/QD-based fluorescence-topographic image fusion directly reveals nano-spatial peak-valley polarities of CD69 and CD71 activation molecules on cell-membrane fluctuations during T-cell activation.

Xiaoxu Lu, Liyun Zhong, Zheng W. Chen, 2011, Immunology letters.

TCR Repertoire, Clonal Dominance, and Pulmonary Trafficking of Mycobacterium-Specific CD4+ and CD8+ T Effector Cells in Immunity Against Tuberculosis

Zheng W. Chen, Crystal Y. Chen, Richard C. Wang, 2010, The Journal of Immunology.

IL-2 Simultaneously Expands Foxp3+ T Regulatory and T Effector Cells and Confers Resistance to Severe Tuberculosis (TB): Implicative Treg–T Effector Cooperation in Immunity to TB

G. Zeng, Zheng W. Chen, Crystal Y. Chen, 2012, The Journal of Immunology.

Phosphoantigen-activated V (cid:1) 2V (cid:2) 2 T cells antagonize IL-2–induced CD4 (cid:3) CD25 (cid:3) Foxp3 (cid:3) T regulatory cells in mycobacterial infection

X. Zhan, H. Sicard, Crystal Y. Chen, 2009 .

Coadministration of Cidofovir and Smallpox Vaccine Reduced Vaccination Side Effects but Interfered with Vaccine-Elicited Immune Responses and Immunity to Monkeypox

Zheng W. Chen, Richard C. Wang, Dan Huang, 2008, Journal of Virology.

DR*W201/P65 Tetramer Visualization of Epitope-Specific CD4 T-Cell during M. tuberculosis Infection and Its Resting Memory Pool after BCG Vaccination

G. Zeng, Zheng W. Chen, Ling Shen, 2009, PloS one.

Definition of APC Presentation of Phosphoantigen (E)-4-Hydroxy-3-methyl-but-2-enyl Pyrophosphate to Vγ2Vδ2 TCR1

Zheng W. Chen, Richard C. Wang, Dan Huang, 2008, The Journal of Immunology.

( Definition of APC Presentation of

Richard C. Wang, Dan Huang, Huiyong Wei, 2008 .

E ( Definition of APC Presentation of

Richard C. Wang, Dan Huang, Huiyong Wei, 2008 .

An atomic-force basis for the bacteriolytic effects of granulysin.

Jiye Cai, G. Zeng, Lifang Jiang, 2012, Colloids and surfaces. B, Biointerfaces.

Immune gene networks of mycobacterial vaccine-elicited cellular responses and immunity.

N. Letvin, Zheng W. Chen, Ling Shen, 2007, The Journal of infectious diseases.

NSOM/QD-Based Direct Visualization of CD3-Induced and CD28-Enhanced Nanospatial Coclustering of TCR and Coreceptor in Nanodomains in T Cell Activation

G. Zeng, Xiaoxu Lu, Liyun Zhong, 2009, PloS one.

Virus infection stages and distinct Th1 or Th17/Th22 T-cell responses in malaria/SHIV coinfection correlate with different outcomes of disease.

Zheng W. Chen, W. Collins, Crystal Y. Chen, 2011, The Journal of infectious diseases.

monocytogenes Listeria Nonhuman Primates Inoculated with 2 T Cells in δ 2 V γ of HMBPP-Specific V Multieffector-Functional Immune Responses

Zheng W. Chen, Ling Shen, Crystal Y. Chen, 2012 .

Listeria monocytogenes Non-human Primates Inoculated with 2 T Cells in δ 2 V γ of HMBPP-Specific V Multieffector-Functional Immune Responses

Zheng W. Chen, Ling Shen, Crystal Y. Chen, 2012 .

Mannosylated graphene oxide as macrophage-targeted delivery system for enhanced intracellular M.tuberculosis killing efficiency.

Jiye Cai, G. Zeng, H. Shen, 2019, Materials science & engineering. C, Materials for biological applications.

Immunization of Vγ2Vδ2 T cells programs sustained effector memory responses that control tuberculosis in nonhuman primates

W. Jacobs, H. Shen, S. Porcelli, 2019, Proceedings of the National Academy of Sciences.

Bis-biguanide dihydrochloride inhibits intracellular replication of M. tuberculosis and controls infection in mice

G. Zeng, H. Shen, Lijun Rong, 2016, Scientific Reports.

SHIV antigen immunization alters patterns of immune responses to SHIV/malaria coinfection and protects against life-threatening SHIV-related malaria.

N. Letvin, N. Freitag, Zheng W. Chen, 2013, The Journal of infectious diseases.

Pathogenic Events in a Nonhuman Primate Model of Oral Poliovirus Infection Leading to Paralytic Poliomyelitis

M. Vignuzzi, R. Andino, Lixia Qian, 2017, Journal of Virology.

Combined megaplex TCR isolation and SMART-based real-time quantitation methods for quantitating antigen-specific T cell clones in mycobacterial infection.

N. Letvin, Zheng W. Chen, Ling Shen, 2006, Journal of immunological methods.

Expansion, Reexpansion, and Recall-Like Expansion of Vγ2Vδ2 T Cells in Smallpox Vaccination and Monkeypox Virus Infection

Zheng W. Chen, Ling Shen, Jialin Jin, 2009, Journal of Virology.

CD4+ T Cells Contain Early Extrapulmonary Tuberculosis (TB) Dissemination and Rapid TB Progression and Sustain Multieffector Functions of CD8+ T and CD3− Lymphocytes: Mechanisms of CD4+ T Cell Immunity

Zheng W. Chen, Crystal Y. Chen, Richard C. Wang, 2014, The Journal of Immunology.

Antigen-specific Vγ2Vδ2 T effector cells confer homeostatic protection against pneumonic plaque lesions

H. Jomaa, A. Reichenberg, M. Hintz, 2009, Proceedings of the National Academy of Sciences.

Inhibition of Adaptive Vγ2Vδ2+ T-Cell Responses during Active Mycobacterial Coinfection of Simian Immunodeficiency Virus SIVmac-Infected Monkeys

M. Simon, N. Letvin, P. Sehgal, 2003, Journal of Virology.

Inhibition of Adaptive V (cid:2) 2V (cid:3) 2 (cid:1) T-Cell Responses during Active Mycobacterial Coinfection of Simian Immunodeﬁciency Virus SIVmac-Infected Monkeys

M. Simon, N. Letvin, P. Sehgal, 2003 .

Development of Vγ2Vδ2+ T Cell Responses during Active Mycobacterial Coinfection of Simian Immunodeficiency Virus-Infected Macaques Requires Control of Viral Infection and Immune Competence of CD4+ T Cells

N. Letvin, P. Sehgal, Zheng W. Chen, 2004 .

Nanocages engineered from Bacillus Calmette-Guerin facilitate protective Vγ2Vδ2 T cell immunity against Mycobacterium tuberculosis infection

G. Zeng, H. Shen, Jiang Pi, 2022, Journal of Nanobiotechnology.

Long noncoding RNA derived from CD244 signaling epigenetically controls CD8+ T-cell immune responses in tuberculosis infection

Xiaohui Xie, G. Zeng, Hui Zhang, 2015, Proceedings of the National Academy of Sciences.

Tuberculosis-Induced Variant IL-4 mRNA Encodes a Cytokine Functioning As Growth Factor for (E)-4-Hydroxy-3-Methyl-But-2-Enyl Pyrophosphate-Specific Vγ2Vδ2 T Cells1

Zhongdao Wu, Zheng W. Chen, Ling Shen, 2009, The Journal of Immunology.

)-4-Hydroxy-3-Methyl-But-2-Enyl E Factor for ( Encodes a Cytokine Functioning As Growth Tuberculosis-Induced Variant IL-4 mRNA

Zhongdao Wu, Zheng W. Chen, Ling Shen, 2008 .

Selective Destruction of Interleukin 23–Induced Expansion of a Major Antigen–Specific &ggr;&dgr; T-Cell Subset in Patients With Tuberculosis

H. Shen, Zheng W. Chen, Ling Shen, 2016, The Journal of infectious diseases.

Clinical Latency and Reactivation of AIDS-Related Mycobacterial Infections

N. Letvin, P. Sehgal, Zheng W. Chen, 2004, Journal of Virology.

Phosphoantigen-activated V gamma 2V delta 2 T cells antagonize IL-2-induced CD4+CD25+Foxp3+ T regulatory cells in mycobacterial infection.

X. Zhan, H. Sicard, Crystal Y. Chen, 2008, Blood.

Phosphoantigen/IL2 Expansion and Differentiation of Vγ2Vδ2 T Cells Increase Resistance to Tuberculosis in Nonhuman Primates

H. Jomaa, W. Jacobs, N. Letvin, 2013, PLoS pathogens.

Clonal Immune Responses of Mycobacterium-Specific γδ T Cells in Tuberculous and Non-Tuberculous Tissues during M. tuberculosis Infection

Keyuan Zhou, Crystal Y. Chen, Richard C. Wang, 2012, PloS one.

Immune Distribution and Localization of Phosphoantigen-Specific Vγ2Vδ2 T Cells in Lymphoid and Nonlymphoid Tissues in Mycobacterium tuberculosis Infection

B. Haynes, W. Jacobs, N. Letvin, 2007, Infection and Immunity.

Immune distribution and localization of phosphoantigen-specific Vgamma2Vdelta2 T cells in lymphoid and nonlymphoid tissues in Mycobacterium tuberculosis infection.

B. Haynes, W. Jacobs, N. Letvin, 2008, Infection and immunity.

Ursolic acid-loaded chitosan nanoparticles induce potent anti-angiogenesis in tumor

Jiye Cai, Chao-min Wu, Zheng W. Chen, 2016, Applied Microbiology and Biotechnology.

Multieffector-Functional Immune Responses of HMBPP-Specific Vγ2Vδ2 T Cells in Nonhuman Primates Inoculated with Listeria monocytogenes ΔactA prfA*

Zheng W. Chen, Ling Shen, Crystal Y. Chen, 2012, The Journal of Immunology.

A Critical Role for CD8 T Cells in a Nonhuman Primate Model of Tuberculosis

William R. Jacobs, Norman L. Letvin, Lisa Halliday, 2009, PLoS pathogens.

NSOM‐ and AFM‐based nanotechnology elucidates nano‐structural and atomic‐force features of a Y. pestis V immunogen‐containing particle vaccine capable of eliciting robust response

Jianbo Chen, Jiye Cai, G. Zeng, 2009, Proteomics.

Immune Distribution and Localization of Phosphoantigen-Speciﬁc V (cid:2) 2V (cid:3) 2 T Cells in Lymphoid and Nonlymphoid Tissues in Mycobacterium tuberculosis Infection (cid:1)

B. Haynes, W. Jacobs, N. Letvin, 2007 .

H. Shen, Zheng W. Chen, Crystal Y. Chen, 2015, European journal of immunology.

Immunity T Cell + Lymphocytes : Mechanisms of CD 4 − T and CD 3 + Functions of CD 8 TB Progression and Sustain Multieffector Tuberculosis ( TB ) Dissemination and Rapid T Cells Contain Early Extrapulmonary + CD 4

Zheng W. Chen, Crystal Y. Chen, Richard C. Wang, 2014 .

Fast‐acting γδ T‐cell subpopulation and protective immunity against infections

H. Shen, Zheng W. Chen, A. Qaqish, 2020, Immunological reviews.