Jin Xu

发表

Oxidative Metabolism as a Modulator of Kratom's Biological Actions.

Samuel T. Slocum, G. Pasternak, J. Pintar, 2021, Journal of medicinal chemistry.

Enhanced κ-opioid receptor-mediated analgesia by antisense targeting the σ1 receptor

G. Pasternak, Ying-Xian Pan, Jin Xu, 1997 .

Mediation of buprenorphine analgesia by a combination of traditional and truncated mu opioid receptor splice variants

G. Pasternak, J. Pintar, M. Ansonoff, 2016, Synapse.

Correction to: Mu Opioids Induce Biased Signaling at the Full-Length Seven Transmembrane C-Terminal Splice Variants of the mu Opioid Receptor Gene, Oprm1

G. Pasternak, Ying-Xian Pan, D. Bassoni, 2020, Cellular and molecular neurobiology.

Mu Opioids Induce Biased Signaling at the Full-Length Seven Transmembrane C-Terminal Splice Variants of the mu Opioid Receptor Gene, Oprm1

G. Pasternak, Ying-Xian Pan, D. Bassoni, 2020, Cellular and molecular neurobiology.

A Truncated Six Transmembrane Splice Variant MOR-1G Enhances Expression of the Full-Length Seven Transmembrane μ-Opioid Receptor through Heterodimerization

Ying-Xian Pan, Jin Xu, Tiffany Zhang, 2020, Molecular Pharmacology.

Differential regulation of Cav2.2 channel exon 37 variants by alternatively spliced μ-opioid receptors

Ying-Xian Pan, G. Zamponi, I. A. Souza, 2019, Molecular Brain.

Truncated mu opioid GPCR variant involvement in opioid-dependent and opioid-independent pain modulatory systems within the CNS

G. Pasternak, Ying-Xian Pan, S. Majumdar, 2016, Proceedings of the National Academy of Sciences.

Pharmacological Characterization of Levorphanol, a G-Protein Biased Opioid Analgesic

G. Pasternak, Ying-Xian Pan, S. Majumdar, 2019, Anesthesia and analgesia.

Mediation of opioid analgesia by a truncated 6-transmembrane GPCR.

G. Pasternak, Ying-Xian Pan, S. Majumdar, 2015, The Journal of clinical investigation.

Genetic dissociation of morphine analgesia from hyperalgesia in mice

G. Pasternak, A. Rajadhyaksha, Ying-Xian Pan, 2017, Psychopharmacology.

Tetrapeptide Endomorphin Analogs Require Both Full Length and Truncated Splice Variants of the Mu Opioid Receptor Gene Oprm1 for Analgesia.

G. Pasternak, J. Pintar, Ying-Xian Pan, 2016, ACS chemical neuroscience.

Involvement of exon 11-associated variants of the mu opioid receptor MOR-1 in heroin, but not morphine, actions

G. Pasternak, Ying-Xian Pan, Jin Xu, 2009, Proceedings of the National Academy of Sciences.

Identification of three new alternatively spliced variants of the rat mu opioid receptor gene: dissociation of affinity and efficacy

G. Pasternak, Ying-Xian Pan, Jin Xu, 2004, Journal of neurochemistry.

Rubsicolins are naturally occurring G-protein-biased delta opioid receptor peptides

G. Pasternak, M. Lill, Ying-Xian Pan, 2018, bioRxiv.

Pharmacological characterization of novel synthetic opioids (NSO) found in the recreational drug marketplace

G. Pasternak, B. Roth, Ying-Xian Pan, 2017, Neuropharmacology.

Identification and differential regional expression of KOR‐3/ORL‐1 gene splice variants in mouse brain

G. Pasternak, Ying-Xian Pan, Jin Xu, 1998, FEBS letters.

Histone deacetylases are required for androgen receptor function in hormone-sensitive and castrate-resistant prostate cancer.

L. Borsu, H. Scher, N. Rosen, 2009, Cancer research.

Exploring Pharmacological Functions of Alternatively Spliced Variants of the Mu Opioid Receptor Gene, Oprm1, via Gene-Targeted Animal Models

L. Cartegni, J. Pintar, Ying-Xian Pan, 2022, International journal of molecular sciences.

Dysregulated expression of the alternatively spliced variant mRNAs of the mu opioid receptor gene, OPRM1, in the medial prefrontal cortex of male human heroin abusers and heroin self‐administering male rats

Y. Hurd, Ying-Xian Pan, Jin Xu, 2020, Journal of neuroscience research.

Differential Expressions of the Alternatively Spliced Variant mRNAs of the µ Opioid Receptor Gene, OPRM1, in Brain Regions of Four Inbred Mouse Strains

G. Pasternak, Ying-Xian Pan, Amanda R. Waxman, 2014, PloS one.

Stabilization of the μ-Opioid Receptor by Truncated Single Transmembrane Splice Variants through a Chaperone-like Action*

G. Pasternak, Y. Hurd, Ying-Xian Pan, 2013, The Journal of Biological Chemistry.

Variants through a Chaperone-like Action Truncated Single Transmembrane Splice-Opioid Receptor by μ Stabilization of the Molecular Bases of Disease :

G. Pasternak, Y. Hurd, Ying-Xian Pan, 2013 .

Morphine Regulates Expression of μ-Opioid Receptor MOR-1A, an Intron-Retention Carboxyl Terminal Splice Variant of the μ-Opioid Receptor (OPRM1) Gene via miR-103/miR-107

G. Pasternak, Ying-Xian Pan, Jin Xu, 2014, Molecular Pharmacology.

Identification of Abundant and Evolutionarily Conserved Opioid Receptor Circular RNAs in the Nervous System Modulated by Morphine

G. Pasternak, Ying-Xian Pan, Takeshi Irie, 2019, Molecular Pharmacology.

Generation of the mu opioid receptor (MOR-1) protein by three new splice variants of the Oprm gene

G. Pasternak, Ying-Xian Pan, Jin Xu, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Isolation and expression of a novel alternatively spliced mu opioid receptor isoform, MOR‐1F

G. Pasternak, Ying-Xian Pan, Jin Xu, 2000, FEBS letters.

Identification of Four Novel Exon 5 Splice Variants of the Mouse μ-Opioid Receptor Gene: Functional Consequences of C-Terminal Splicing

G. Pasternak, Ying-Xian Pan, H. Moskowitz, 2005, Molecular Pharmacology.

Alternative Pre-mRNA Splicing of the Mu Opioid Receptor Gene, OPRM1: Insight into Complex Mu Opioid Actions

L. Cartegni, Ying-Xian Pan, Sha Liu, 2021, Biomolecules.

A Heroin Addiction Severity-Associated Intronic Single Nucleotide Polymorphism Modulates Alternative Pre-mRNA Splicing of the μ Opioid Receptor Gene OPRM1 via hnRNPH Interactions

G. Pasternak, Y. Hurd, R. Klein, 2014, The Journal of Neuroscience.

Stabilization of morphine tolerance with long-term dosing: Association with selective upregulation of mu-opioid receptor splice variant mRNAs

G. Pasternak, Ying-Xian Pan, Jin Xu, 2014, Proceedings of the National Academy of Sciences.

Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine

Richard C. Rice, G. Pasternak, L. Cartegni, 2017, The Journal of clinical investigation.

Identification and characterization of two new human mu opioid receptor splice variants, hMOR-1O and hMOR-1X.

G. Pasternak, Ying-Xian Pan, Jin Xu, 2003, Biochemical and biophysical research communications.

Structure and expression of subunit A from the bovine chromaffin cell vacuolar ATPase

G. E. Dean, Ying-Xian Pan, J. Xu, 1991, FEBS letters.

Isolation and characterization of alternatively spliced variants of the mouse sigma1 receptor gene, Sigmar1

G. Pasternak, Ying-Xian Pan, Jin Xu, 2017, PloS one.

Cloning and Characterization of a Mouse σ1 Receptor

G. Pasternak, Ying-Xian Pan, B. Wan, 1998 .

Structure-based design of bitopic ligands for the µ-opioid receptor

Samuel T. Slocum, B. Roth, V. Katritch, 2022, Nature.

Truncated &mgr;-Opioid Receptors With 6 Transmembrane Domains Are Essential for Opioid Analgesia

G. Pasternak, Ying-Xian Pan, S. Majumdar, 2017, Anesthesia and analgesia.

Isolating and characterizing three alternatively spliced mu opioid receptor variants: mMOR‐1A, mMOR‐1O, and mMOR‐1P

G. Pasternak, Ying-Xian Pan, Jin Xu, 2014, Synapse.

Identification and characterization of seven new exon 11-associated splice variants of the rat mu opioid receptor gene, OPRM1

Gavril W Pasternak, G. Pasternak, Ying-Xian Pan, 2011, Molecular pain.

Isolation and characterization of new exon 11‐associated N‐terminal splice variants of the human mu opioid receptor gene

G. Pasternak, Y. Hurd, Ying-Xian Pan, 2009, Journal of neurochemistry.

Differential regulation of Cav2.2 channel exon 37 variants by alternatively spliced μ-opioid receptors

Ying-Xian Pan, G. Zamponi, I. A. Souza, 2019, Molecular Brain.

Morphine modulates the expression of mu‐opioid receptor exon 5‐associated full‐length C‐terminal splice variants by upregulating miR‐378a‐3p

Ying-Xian Pan, Jin Xu, Zhigang Lu, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Mu Opioids Induce Biased Signaling at the Full-Length Seven Transmembrane C-Terminal Splice Variants of the mu Opioid Receptor Gene, Oprm1

G. Pasternak, Ying-Xian Pan, D. Bassoni, 2020, Cellular and Molecular Neurobiology.

Characterizing exons 11 and 1 promoters of the mu opioid receptor (Oprm) gene in transgenic mice

Ying-Xian Pan, Jin Xu, Mingming Xu, 2006, BMC Molecular Biology.

Identification and characterization of three new alternatively spliced mu-opioid receptor isoforms.

G. Pasternak, Ying-Xian Pan, J. Xu, 1999, Molecular pharmacology.

Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β-Arrestin-2.

G. Pasternak, Ying-Xian Pan, A. Borics, 2016, Journal of medicinal chemistry.

Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine

Richard C. Rice, G. Pasternak, L. Cartegni, 2017, The Journal of clinical investigation.