C. Gouws

发表

Recent advances in three-dimensional cell culturing to assess liver function and dysfunction: from a drug biotransformation and toxicity perspective

S. Fey, K. Wrzesinski, J. Hamman, 2018, Toxicology mechanisms and methods.

Models used to screen for the treatment of multidrug resistant cancer facilitated by transporter-based efflux

C. Willers, J. Hamman, C. Gouws, 2019, Journal of Cancer Research and Clinical Oncology.

Drug Bioavailability Enhancing Agents of Natural Origin (Bioenhancers) that Modulate Drug Membrane Permeation and Pre-Systemic Metabolism

M. Weyers, J. Hamman, J. Steenekamp, 2019, Pharmaceutics.

A sub-chronic Xysmalobium undulatum hepatotoxicity investigation in HepG2/C3A spheroid cultures compared to an in vivo model.

S. Fey, K. Wrzesinski, J. Hamman, 2019, Journal of ethnopharmacology.

Toxicity and anti-prolific properties of Xysmalobium undulatum water extract during short-term exposure to two-dimensional and three-dimensional spheroid cell cultures

S. Fey, K. Wrzesinski, J. Hamman, 2018, Toxicology mechanisms and methods.

Cell-free DNA in a three-dimensional spheroid cell culture model: A preliminary study.

K. Wrzesinski, A. Bronkhorst, C. Calitz, 2017, The international journal of biochemistry & cell biology.

University of Southern Denmark Toxicity and anti-prolific properties of Xysmalobium undulatum water extract during short term exposure to two-dimensional and three-dimensional spheroid cell cultures Calitz,

Krzysztof, S. Fey, J. Hamman, 2018 .

Anticancer Potential of Sutherlandia frutescens and Xysmalobium undulatum in LS180 Colorectal Cancer Mini-Tumors

K. Wrzesinski, C. Willers, C. Calitz, 2021, Molecules.

Herbal hepatotoxicity: current status, examples, and challenges

D. Steyn, J. Steenekamp, C. Muller, 2015, Expert opinion on drug metabolism & toxicology.

The interactive effects of drought and heat stress on photosynthetic efficiency and biochemical defense mechanisms of Amaranthus species

C. Gouws, J. Berner, M. H. Netshimbupfe, 2022, Plant-environment interactions.

Characterization of an Alginate Encapsulated LS180 Spheroid Model for Anti-colorectal Cancer Compound Screening.

S. Fey, K. Wrzesinski, C. Willers, 2020, ACS medicinal chemistry letters.

Evaluating in vitro cytotoxic effects of Artemisia afra and Artemisia annua infusions against selected lung cancer cell lines

F. van der Kooy, C. Willers, J. Hamman, 2022, South African Journal of Botany.

Herb-Drug Pharmacokinetic Interactions: Transport and Metabolism of Indinavir in the Presence of Selected Herbal Products

J. Hamman, J. Steenekamp, L. Wiesner, 2015, Molecules.

Aloe vera gel and whole leaf extract: functional and versatile excipients for drug delivery?

J. Hamman, C. Gouws, A. Laux, 2019, Expert opinion on drug delivery.

Combining Chemical Permeation Enhancers for Synergistic Effects

J. Hamman, M. Aucamp, C. Gouws, 2016, European Journal of Drug Metabolism and Pharmacokinetics.

A novel NCI‐H69V small cell lung cancer functional mini‐tumor model for future treatment screening applications

K. Wrzesinski, C. Willers, C. Gouws, 2022, Biotechnology progress.

Impact of traditional African medicine on drug metabolism and transport

J. Hamman, J. Steenekamp, C. Calitz, 2014, Expert opinion on drug metabolism & toxicology.

Evaluation of Isolated Fractions of Aloe vera Gel Materials on Indinavir Pharmacokinetics: In vitro and in vivo Studies.

S. Ellis, D. Steyn, D. Otto, 2016, Current drug delivery.

Treatment of skin disorders with Aloe materials.

J. Hamman, C. Gouws, H. Svitina, 2019, Current pharmaceutical design.

Combining Chemical Permeation Enhancers for Synergistic Effects

J. Hamman, M. Aucamp, C. Gouws, 2016, European Journal of Drug Metabolism and Pharmacokinetics.

The importance and use of Amaranthus for crop diversification in the SADC region

F. van der Kooy, C. Gouws, J. Berner, 2023, South African Journal of Botany.

Molecular mechanisms and associated cell signalling pathways underlying the anticancer properties of phytochemical compounds from Aloe species (Review)

J. Hamman, C. Gouws, H. Svitina, 2021, Experimental and therapeutic medicine.

Recent developments in our understanding of the implications of traditional African medicine on drug metabolism

J. Hamman, Josias H Hamman, C. Gouws, 2018, Expert opinion on drug metabolism & toxicology.

Efflux as a mechanism of antimicrobial drug resistance in clinical relevant microorganisms: the role of efflux inhibitors

C. Willers, J. Hamman, Johannes F. Wentzel, 2017, Expert opinion on therapeutic targets.

What are the dangers of drug interactions with herbal medicines?

J. Hamman, C. Gouws, 2020, Expert Opinion on Drug Metabolism & Toxicology.

O6-methylguanine-DNA methyltransferase (MGMT): can function explain a suicidal mechanism?

C. Gouws, P. J. Pretorius, 2011, Medical hypotheses.

Tyrosinemia type I as a model for studying epigenetic events in the aetiology of metabolic disease associated hepatocarcinoma

C. Gouws, 2011 .

Combination therapy of Western drugs and herbal medicines: recent advances in understanding interactions involving metabolism and efflux

D. Steyn, J. Hamman, J. Steenekamp, 2012, Expert opinion on drug metabolism & toxicology.

Clinostat 3D Cell Culture: Protocols for the Preparation and Functional Analysis of Highly Reproducible, Large, Uniform Spheroids and Organoids.

S. Fey, K. Wrzesinski, B. Korzeniowska, 2021, Methods in molecular biology.

Isolation and in vitro permeation of phenylpropylamino alkaloids from Khat (Catha edulis) across oral and intestinal mucosal tissues.

J. Hamman, A. Viljoen, S. Combrinck, 2016, Journal of ethnopharmacology.

The anti-neoplastic activity of Artemisia afra in breast cancer cell lines

F. van der Kooy, C. Gouws, O. Oladimeji, 2023, South African Journal of Botany.

Herbal hepatotoxicity: current status, examples, and challenges

D. Steyn, J. Steenekamp, C. Muller, 2015 .

Assessing the DNA methylation status of single cells with the comet assay.

G. Koekemoer, Johannes F. Wentzel, C. Gouws, 2010, Analytical biochemistry.

A Novel NCI-H69AR Drug-Resistant Small-Cell Lung Cancer Mini-Tumor Model for Anti-Cancer Treatment Screening

K. Wrzesinski, D. Steyn, C. Gouws, 2023, Cells.

Assessing the DNA methylation status of single cells with the comet assay.

G. Koekemoer, Johannes F. Wentzel, C. Gouws, 2010, Analytical Biochemistry.

Isolation and in vitro permeation of phenylpropylamino alkaloids from Khat (Catha edulis) across oral and intestinal mucosal tissues.

J. Hamman, A. Viljoen, S. Combrinck, 2016, Journal of ethnopharmacology.

The effect of environmental stressors on the anticancer potential of Amaranthus hypochondriacus aqueous extracts and fractions.

F. van der Kooy, C. Gouws, O. Oladimeji, 2023, Natural product research.

Recent advances in three-dimensional cell culturing to assess liver function and dysfunction: from a drug biotransformation and toxicity perspective

S. Fey, J. Hamman, C. Gouws, 2018, Toxicology mechanisms and methods.

Insights into the wound-healing properties of medicinally important South African Bulbine species – a comparative study

M. Sandasi, Ramoagi T. Segone, C. Gouws, 2024, Journal of Ethnopharmacology.