S. Bonacorsi

发表

Reductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and Dogs

P. Lam, K. He, R. Knabb, 2008, Drug Metabolism and Disposition.

Evaluation of the Lysophosphatidic Acid Receptor Type 1 Radioligand 11C-BMT-136088 for Lung Imaging in Rhesus Monkeys

Richard E Carson, Jean-Dominique Gallezot, Shu-Fei Lin, 2017, The Journal of Nuclear Medicine.

Synthesis of carbon‐14 labelled midazolam

S. Bonacorsi, J. Easter, Balu N Balasubramanian, 2009 .

Overcoming bioanalytical challenges in an Onglyza(®) intravenous [(14)C]microdose absolute bioavailability study with accelerator MS.

Jim X. Shen, W. Humphreys, S. Dueker, 2012, Bioanalysis.

Resea R ch aR ticle Mini focus: a M s & M ic R odosing

S. Dueker, S. Bonacorsi, L. Cojocaru, 2012 .

Synthesis of isotopically labeled daclatasvir for use in human clinical studies.

S. Bonacorsi, J. Easter, R. Burrell, 2016, Journal of labelled compounds & radiopharmaceuticals.

Chemoselective methionine bioconjugation: site-selective fluorine-18 labeling of proteins and peptides.

A. Allentoff, Richard Y.-C. Huang, D. Donnelly, 2020, Bioconjugate chemistry.

LC-MS/MS bioanalysis of plasma 1, 14-tetradecanedioic acid and 1, 16-hexadecanedioic acid as candidate biomarkers for organic anion-transporting polypeptide mediated drug-drug interactions.

Yan J. Zhang, Rasa Santockyte, J. Gan, 2018, Bioanalysis.

Synthesis and Biologic Evaluation of a Novel 18F-Labeled Adnectin as a PET Radioligand for Imaging PD-L1 Expression

Martin C. Wright, Joonyoung Kim, W. Hayes, 2017, The Journal of Nuclear Medicine.

Tissue distribution and tumor uptake of folate receptor–targeted epothilone folate conjugate, BMS-753493, in CD2F1 mice after systemic administration

W. Humphreys, F. Lee, J. Gan, 2016, Acta pharmaceutica Sinica. B.

Synthesis of unlabelled and stable-isotope-labelled glucuronide metabolites of dapagliflozin and synthesis of stable-isotope-labelled dapagliflozin.

M. Yao, S. Bonacorsi, J. Caceres-Cortes, 2017, Journal of labelled compounds & radiopharmaceuticals.

Characterization of the In Vitro and In Vivo Metabolism and Disposition and Cytochrome P450 Inhibition/Induction Profile of Saxagliptin in Human

W. Humphreys, D. Boulton, R. Iyer, 2012, Drug Metabolism and Disposition.

Characterization of the In Vitro and In Vivo Metabolism and Disposition and P450 Inhibition/Induction Profile of Saxagliptin in Human

W. Humphreys, D. Boulton, Kai Cao, 2012 .

Carbon‐14 labeling of Saxagliptin (BMS‐477118)

R. Hanson, R. Iyer, H. Su, 2007 .

Nucleophilic (Radio)Fluorination of Redox-Active Esters via Radical-Polar Crossover Enabled by Photoredox Catalysis.

W. R. Ewing, D. Donnelly, A. Doyle, 2020, Journal of the American Chemical Society.

Synthesis and Preclinical Evaluation of a 68Ga-Labeled Adnectin, 68Ga-BMS-986192, as a PET Agent for Imaging PD-L1 Expression

W. Hayes, P. Morin, W. Weber, 2021, The Journal of Nuclear Medicine.

68Ga-BMS-986192 as a PET Agent for Imaging PD-L1 Expression

Katja, W. Hayes, P. Morin, 2021 .

Synthesis of 14C-labeled and 13C-,15N-labeled dasatinib and its piperazine N-dealkyl metabolite

A. Allentoff, M. Ogan, S. Bonacorsi, 2008 .

Synthesis of stable isotope-labeled epothilone D using a degradation-reconstruction approach.

S. Bonacorsi, R. Burrell, W. Turley, 2015, Journal of labelled compounds & radiopharmaceuticals.

Biotransformation profiling of [(14)C]ixabepilone in human plasma, urine and feces samples using accelerator mass spectrometry (AMS).

W. Humphreys, J. Beijnen, J. Beumer, 2009, Drug metabolism and pharmacokinetics.

Synthesis of lead LFA-1 antagonist [14C]spyrocyclic hydantoin

L. Leith, M. Ogan, B. Maxwell, 2009 .

Synthesis and characterization of tritium labeled N-((R)-1-((S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-3-methyl-1-oxobutan-2-yl)-3-sulfamoylbenzamide.

J. Hynes, S. Bonacorsi, Balu N Balasubramanian, 2015, Journal of labelled compounds & radiopharmaceuticals.

The synthesis of radiolabeled Irbesartan using N,N‐dimethyl[14C]formamide as a source of carbon‐14 isotope

S. Bonacorsi, I. Ekhato, 2011 .

Synthesis of the anxiolytic agent [14C] 6-hydroxy-buspirone for use in a human ADME study

R. Iyer, S. Bonacorsi, Balu N Balasubramanian, 2007 .

METABOLISM OF [14C]GEMOPATRILAT AFTER ORAL ADMINISTRATION TO RATS, DOGS, AND HUMANS

M. Jemal, Sanaullah Khan, R. Iyer, 2006, Drug Metabolism and Disposition.

METABOLISM OF [ 14 C]GEMOPATRILAT AFTER ORAL ADMINISTRATION TO RATS, DOGS, AND HUMANS

M. Jemal, Sanaullah Khan, R. Iyer, 2006 .

GEMOPATRILAT AFTER ORAL ADMINISTRATION TO RATS , DOGS , AND HUMANS

Khan, Sanaullah, M. Jemal, 2006 .

Comparative biotransformation of radiolabeled [(14)C]omapatrilat and stable-labeled [(13)C(2)]omapatrilat after oral administration to rats, dogs, and humans.

K. Kripalani, Sanaullah Khan, B. Malhotra, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Metabolism of [(14)C]omapatrilat, a sulfhydryl-containing vasopeptidase inhibitor in humans.

V. Roongta, K. Kripalani, B. Malhotra, 2001, Drug Metabolism And Disposition.

OMAPATRILAT , A SULFHYDRYL-CONTAINING VASOPEPTIDASE INHIBITOR IN HUMANS 1

V. Roongta, K. Kripalani, B. Malhotra, 2000 .

STRUCTURAL ELUCIDATION OF HUMAN OXIDATIVE METABOLITES OF MURAGLITAZAR: USE OF MICROBIAL BIOREACTORS IN THE BIOSYNTHESIS OF METABOLITE STANDARDS

Yande Huang, W. Humphreys, Mingshe Zhu, 2006, Drug Metabolism and Disposition.

Pd(II)-catalyzed C-H iodination using molecular I2 as the sole oxidant.

jin-quan yu, Yi Hu, S. Bonacorsi, 2013, Journal of the American Chemical Society.

Stereochemistry of the Thermal Isomerizations of trans-1-Ethenyl-2-phenylcyclopropane to 4-Phenylcyclopentene

J. Baldwin, S. Bonacorsi, 1996 .

Stereochemistry of the Thermal Isomerizations of (1R,2S)-1-(E-1-Propenyl)-2-phenylcyclopropane to 3-Methyl-4-phenylcyclopentenes

J. Baldwin, S. Bonacorsi, 1994 .

Synthesis of an adenine N-3 substituted CBI adduct by alkylation of adenine with a 1-iodomethylindoline seco-CBI precursor

A. Allentoff, M. Wallace, S. Bonacorsi, 2018, Tetrahedron.

Direct Carbon Isotope Exchange through Decarboxylative Carboxylation.

A. Allentoff, Cian Kingston, P. Baran, 2018, Journal of the American Chemical Society.

Apixaban Metabolism and Pharmacokinetics after Oral Administration to Humans

W. Humphreys, K. He, C. Frost, 2009, Drug Metabolism and Disposition.

An alternative and robust synthesis of [(13) C4 ]Baraclude® (entecavir).

S. Bonacorsi, J. Easter, R. Burrell, 2013, Journal of labelled compounds & radiopharmaceuticals.

Metabolism and Disposition of Dasatinib after Oral Administration to Humans

W. Humphreys, F. Lee, A. Allentoff, 2008, Drug Metabolism and Disposition.

Synthesis of Biologically Active Piperidine Metabolites of Clopidogrel: Determination of Structure and Analyte Development.

P. Lam, W. Humphreys, A. Mathur, 2015, The Journal of organic chemistry.

Whole body PD-1 and PD-L1 positron emission tomography in patients with non-small-cell lung cancer

R. Boellaard, G. V. van Dongen, A. Windhorst, 2018, Nature Communications.

Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys

W. Humphreys, V. Arora, K. He, 2008, Drug Metabolism and Disposition.

Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys

W. Humphreys, V. Arora, K. He, 2008, Drug Metabolism and Disposition.

Synthesis of carbon-14 and stable isotope labeled Avagacestat: a novel gamma secretase inhibitor for the treatment of Alzheimer's disease.

R. Olson, M. Cassidy, S. Bonacorsi, 2014, Journal of labelled compounds & radiopharmaceuticals.

Synthesis of [D4]- and [D7]-4β-hydroxycholesterols for use in a novel drug–drug interaction assay

S. Bonacorsi, J. Onorato, R. Burrell, 2012 .

Synthesis and Preclinical Evaluation of a 68 Ga-Labeled Adnectin, 68 Ga-BMS-986192, as a PET Agent for Imaging PD-L1 Expression

W. Hayes, P. Morin, W. Weber, 2021 .

Synthesis of Carbon-14 and Stable Isotope Labeled Censavudine.

A. Ortiz, S. Bonacorsi, Zhongping Shi, 2022, Journal of labelled compounds & radiopharmaceuticals.

A facile and efficient synthesis of d3‐labelled Reyataz™

J. Barrish, L. Leith, S. Bonacorsi, 2005 .

Comparative Metabolism of Radiolabeled Muraglitazar in Animals and Humans by Quantitative and Qualitative Metabolite Profiling

W. Humphreys, Haiying Zhang, Litao Zhang, 2007, Drug Metabolism and Disposition.

Stereochemistry of the Thermal Conversion of 1‐Vinyl‐2,3‐cis‐dideuteriocyclobutane to Butadiene and 1,2‐Dideuterioethylenes

J. Baldwin, D. K. Lewis, S. Bonacorsi, 1996 .

Radiosynthesis and preclinical PET evaluation of 89Zr-nivolumab (BMS-936558) in healthy non-human primates.

Joonyoung Kim, W. Hayes, P. Morin, 2017, Bioorganic & medicinal chemistry.

Synthesis of a stable isotopically labeled universal surrogate peptide for use as an internal standard in LC-MS/MS bioanalysis of human IgG and Fc-fusion protein drug candidates.

A. Allentoff, C. Mapelli, V. Lee, 2014, Journal of labelled compounds & radiopharmaceuticals.

BMS-986327 as a novel PET imaging agent for assessment of LPA1 receptors in IPF

Joonyoung Kim, W. Hayes, P. Chow, 2019, Rare ILD/DPLD.

Correction to "Synthesis of Biologically Active Piperidine Metabolites of Clopidogrel: Determination of Structure and Analyte Development".

P. Lam, W. Humphreys, A. Mathur, 2015, Journal of Organic Chemistry.

Synthesis of [1,2‐3H]ethylamine hydrochloride and [3H]‐labeled apadenoson for a human ADME study

W. Humphreys, P. Crane, Donglu Zhang, 2008 .

Molecular Imaging and the PD-L1 Pathway: From Bench to Clinic

W. Hayes, S. Bonacorsi, W. Weber, 2021, Frontiers in Oncology.

Metabolism and Disposition of 14C-Labeled Peliglitazar in Humans

W. Humphreys, Donglu Zhang, Lifei Wang, 2011, Drug Metabolism and Disposition.

The synthesis and analysis of [phenyl-14 C(U)]BMS-770767 and [13 C6 ]BMS-770767 for use in discovery biotransformation, human ADME and bioanalytical studies.

B. Maxwell, S. Bonacorsi, 2016, Journal of labelled compounds & radiopharmaceuticals.

The syntheses of [(14) C]BMS-823778 for use in a human ADME clinical study and of [(13) CD3 (13) CD2 ]BMT-094817, a stable-isotope labeled standard of a newly detected human metabolite.

B. Maxwell, S. Bonacorsi, M. Lago, 2016, Journal of labelled compounds & radiopharmaceuticals.

Synthesis of Tritium Labeled 30 KDa PEG and Conjugation to form [3 H]Pegbelfermin.

S. Bonacorsi, J. Easter, R. Burrell, 2021, Journal of labelled compounds & radiopharmaceuticals.

Development of a Carbon-14 Labeling Approach to Support Disposition Studies with a Pegylated Biologic

A. D. Rodrigues, P. Morin, S. Emanuel, 2012, Drug Metabolism and Disposition.

Synthesis of multi‐labeled [14C]Aripiprazole

S. Bonacorsi, Stephen C. Waller, J. K. Rinehart, 2006 .

Synthesis of [3α-(3) H] 17α-hydroxy pregnenolone and [3α-(3) H] pregnenolone.

A. Balog, S. Bonacorsi, Sharon X Gong, 2014, Journal of labelled compounds & radiopharmaceuticals.

Distinguishing a phosphate ester prodrug from its isobaric sulfate metabolite by mass spectrometry without the metabolite standard.

Steven T. Wu, M. Jemal, S. Bonacorsi, 2009, Rapid communications in mass spectrometry : RCM.

Pd(II)-catalyzed C-H iodination using molecular I2 as the sole oxidant.

jin-quan yu, Yi Hu, S. Bonacorsi, 2013, Journal of the American Chemical Society.

Development, Characterization, and Radiation Dosimetry Studies of ^18F-BMS-986229, a ^18F-Labeled PD-L1 Macrocyclic Peptide PET Tracer

N. Meanwell, Tritin Tran, P. Chow, 2023, Molecular imaging and biology.

A novel synthesis of [2-14C]2,5-dichloropyrimidine

B. Maxwell, S. Bonacorsi, Hongui Wu, 2011 .

Development of a lysophosphatidic acid receptor 1 (LPA1) radioligand for lung imaging with PET

Yiyun Huang, R. Carson, N. Nabulsi, 2014 .