G. Marverti

发表

Mass spectrometric/bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides.

Maria Paola Costi, F. Esposito, P. Perco, 2014, Journal of proteome research.

The 1,10-Phenanthroline Ligand Enhances the Antiproliferative Activity of DNA-Intercalating Thiourea-Pd(II) and -Pt(II) Complexes Against Cisplatin-Sensitive and -Resistant Human Ovarian Cancer Cell Lines

Maria Paola Costi, C. Imbriano, G. Ponterini, 2019, International journal of molecular sciences.

Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations

Maria Paola Costi, S. Mangani, G. Ponterini, 2021, Cancers.

Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer cells.

Maria Paola Costi, S. Piras, P. Corona, 2009, European journal of pharmacology.

Inside the biochemical pathways of thymidylate synthase perturbed by anticancer drugs: Novel strategies to overcome cancer chemoresistance.

Maria Paola Costi, G. Ponterini, Y. G. Assaraf, 2015, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Heat shock protein 90 and serine/threonine kinase B-Raf inhibitors have overlapping chemical space

J. Bajorath, G. Rastelli, A. Anighoro, 2017 .

Transcriptional Activation and Cell Cycle Block Are the Keys for 5-Fluorouracil Induced Up-Regulation of Human Thymidylate Synthase Expression

H. Myllykallio, U. Liebl, G. Marverti, 2012, PloS one.

Proteomic and Bioinformatic Studies for the Characterization of Response to Pemetrexed in Platinum Drug Resistant Ovarian Cancer

Maria Paola Costi, F. Magni, E. Braicu, 2018, Front. Pharmacol..

Characterization of the cell growth inhibitory effects of a novel DNA-intercalating bipyridyl-thiourea-Pt(II) complex in cisplatin-sensitive and—resistant human ovarian cancer cells

M. G. Monti, F. Wolf, M. Montanari, 2011, Investigational New Drugs.

Stimulation of cis-diamminedichloroplatinum(II) accumulation by modulation of passive permeability with genistein: an altered response in accumulation-defective resistant cells.

P. Andrews, G. Marverti, 1996, Clinical cancer research : an official journal of the American Association for Cancer Research.

A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells

Maria Paola Costi, G. Ponterini, E. Leo, 2020, International journal of molecular sciences.

Exploring the Biological Activity of a Library of 1,2,5-Oxadiazole Derivatives Endowed With Antiproliferative Activity

M. Mori, A. Asai, F. Meneghetti, 2018, AntiCancer Research.

Spermidine/spermine N1-acetyltransferase transient overexpression restores sensitivity of resistant human ovarian cancer cells to N1,N12-bis(ethyl)spermine and to cisplatin.

A. Pegg, S. Bettuzzi, A. Caporali, 2005, Carcinogenesis.

Edinburgh Research Explorer Depletion of Trichoplein (TpMs) Causes Chromosome MisSegregation, DNA Damage and Chromosome Instability in Cancer Cells

D. Guardavaccaro, S. Mai, A. Caporali, 2020 .

Studies on the anti-proliferative effects of novel DNA-intercalating bipyridyl-thiourea-Pt(II) complexes against cisplatin-sensitive and -resistant human ovarian cancer cells.

M. Bergomi, C. Frassineti, M. D. Di Pietro, 2008, Journal of inorganic biochemistry.

Telomere Dysfunction Is Associated with Altered DNA Organization in Trichoplein/Tchp/Mitostatin (TpMs) Depleted Cells

S. Mai, A. Caporali, G. Marverti, 2022, Biomedicines.

Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth

Maria Paola Costi, G. Ponterini, P. Linciano, 2019, Molecules.

Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth.

Maria Paola Costi, M. Mor, G. Ponterini, 2018, Journal of medicinal chemistry.

2-deoxy-d-ribose-induced apoptosis in HL-60 cells is associated with the cell cycle progression by spermidine.

C. Franceschi, D. Barbieri, G. Marverti, 1999, Biochemical and biophysical research communications.

Modulation of the expression of folate cycle enzymes and polyamine metabolism by berberine in cisplatin-sensitive and -resistant human ovarian cancer cells.

Maria Paola Costi, M. G. Monti, C. Frassineti, 2013, International journal of oncology.

Distamycin A and derivatives as synergic drugs in cisplatin-sensitive and -resistant ovarian cancer cells

Maria Paola Costi, M. G. Monti, C. Frassineti, 2011, Amino Acids.

Synthesis, cytotoxic and combined cDDP activity of new stable curcumin derivatives.

M. Saladini, E. Ferrari, G. Marverti, 2009, Bioorganic & medicinal chemistry.

N1,N12‐bis(ethyl)spermine effect on growth of cis‐diamminedichloroplatinum(II)‐sensitive and ‐resistant human ovarian‐carcinoma cell lines

D. Quaglino, D. Barbieri, G. Marverti, 1998, International journal of cancer.

Modulation of cis-diamminedichloroplatinum (II) accumulation and cytotoxicity by spermine in sensitive and resistant human ovarian carcinoma cells.

P. Andrews, D. Barbieri, G. Marverti, 1997, European journal of cancer.

Polyamine depletion switches the form of 2-deoxy-D-ribose-induced cell death from apoptosis to necrosis in HL-60 cells.

M. G. Monti, M. Montanari, G. Marverti, 2004, The international journal of biochemistry & cell biology.

Cisplatin-resistance modulates the effect of protein synthesis inhibitors on spermidine/spermine N(1)-acetyltransferase expression.

M. G. Monti, S. Bettuzzi, A. Caporali, 2004, The international journal of biochemistry & cell biology.

Polyamine depletion protects HL-60 cells from 2-deoxy-D-ribose-induced apoptosis.

C. Franceschi, M. G. Monti, L. Pernecco, 1998, Life sciences.

Structural, Hirshfeld surface and in vitro cytotoxicity evaluation of five new N-aryl-N’-alkoxycarbonyl thiocarbamide derivatives

S. Pandey, S. Rai, G. Marverti, 2020 .

Differential induction of spermidine/spermine N1-acetyltransferase activity in cisplatin-sensitive and -resistant ovarian cancer cells in response to N1,N12-bis(ethyl)spermine involves transcriptional and post-transcriptional regulation.

M. G. Monti, S. Bettuzzi, G. Marverti, 2001, European Journal of Cancer.

Copper (I) complexes based on novel N, N′-disubstituted thiocarbamides: Synthesis, spectroscopic, in vitro cytotoxicity, DNA damage and G0/G1 cell cycle arrest studies

S. Pandey, H. Mishra, J. Jasinski, 2019, Inorganica Chimica Acta.

N-(naphthyl)-N′-(methoxy carbonyl)thiocarbamide and its Cu(I) complex: synthesis, spectroscopic, X-ray, DFT and in vitro cytotoxicity study

S. Pandey, R. Butcher, G. Marverti, 2015 .

Newly synthesized curcumin derivatives: crosstalk between chemico-physical properties and biological activity.

Carol Imbriano, V. Basile, C. Imbriano, 2011, Journal of medicinal chemistry.

Synthesis, characterization, Hirshfeld surface, cytotoxicity, DNA damage and cell cycle arrest studies of N, N-diphenyl-N'-(biphenyl-4-carbonyl/4-chlorobenzoyl) thiocarbamides

S. Pandey, S. Rai, J. Jasinski, 2019, Journal of Molecular Structure.

Monodentate Coordination of N, N′-Disubstituted Thiocarbamide Ligands: Syntheses, Structural Analyses, In Vitro Cytotoxicity and DNA Damage Studies of Cu(I) Complexes

S. Pandey, R. Butcher, G. Marverti, 2018 .

Synthesis, characterisation, Hirshfeld surface and in vitro cytotoxicity evaluation of new N-aryl-N′-Alkoxycarbonyl thiocarbamide derivatives

S. Pandey, S. Rai, J. Jasinski, 2020 .

Copper(I) complexes of N-(2/4 methoxy/2-chloro-4-nitro)phenyl-N′ (methoxycarbonyl)thiocarbamides as potential anticancer agents: Synthesis, crystal structure, in vitro cytotoxicity and DNA damage studies

S. Pandey, R. Butcher, G. Marverti, 2019, Polyhedron.

Experimental and theoretical exploration of molecular structure and anticancer properties of two N, N′–disubstituted thiocarbamide derivatives

M. Tiwari, S. Pandey, J. Jasinski, 2019, Journal of Molecular Structure.

Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library

Maria Paola Costi, M. Bolognesi, M. Mor, 2022, Pharmaceutics.

Synthesis, molecular structure exploration and in vitro cytotoxicity screening of five novel N, N′- disubstituted thiocarbamide derivatives

S. Pandey, R. Butcher, G. Marverti, 2018 .

Synthesis, spectroscopic, crystal structure and in vitro cytotoxicity studies of N-thiophenoyl-N′-substituted phenyl thiocarbamide derivatives

S. Pandey, J. Jasinski, G. Marverti, 2019, Journal of Molecular Structure.

Distamycin A and derivatives as synergic drugs in cisplatin-sensitive and -resistant ovarian cancer cells

Maria Paola Costi, M. G. Monti, C. Frassineti, 2012, Amino Acids.

1H, 13C, 195Pt NMR study on platinum(II) interaction with sulphur containing Amadori compounds

M. Saladini, M. Rossi, E. Ferrari, 2007 .

Spermidine/spermine N1-acetyltranferase modulation by novel folate cycle inhibitors in cisplatin-sensitive and -resistant human ovarian cancer cell lines.

Maria Paola Costi, M. G. Monti, S. Piras, 2010, Gynecologic oncology.

Synthesis, chemical and biological studies on new Fe(3+)-glycosilated beta-diketo complexes for the treatment of iron deficiency.

M. Saladini, C. Frassineti, M. Ferrali, 2008, European journal of medicinal chemistry.

Repurposing of Drugs Targeting YAP-TEAD Functions

Maria Paola Costi, M. Bolognesi, M. Mor, 2018, Cancers.

Depletion of Trichoplein (TpMs) Causes Chromosome Mis-Segregation, DNA Damage and Chromosome Instability in Cancer Cells

D. Guardavaccaro, S. Mai, A. Caporali, 2020, Cancers.

Targeting Oxidatively Induced DNA Damage Response in Cancer: Opportunities for Novel Cancer Therapies

G. Marverti, D. D’Arca, Angela Lauriola, 2018, Oxidative medicine and cellular longevity.

pH-Promoted Release of a Novel Anti-Tumour Peptide by “Stealth” Liposomes: Effect of Nanocarriers on the Drug Activity in Cis-Platinum Resistant Cancer Cells

Maria Paola Costi, G. Ponterini, E. Leo, 2018, Pharmaceutical Research.

Internalization and stability of a thymidylate synthase Peptide inhibitor in ovarian cancer cells.

Maria Paola Costi, G. Ponterini, G. Cannazza, 2014, Journal of medicinal chemistry.

Human Thymidylate Synthase Inhibitors Halting Ovarian Cancer Growth.

Maria Paola Costi, G. Ponterini, C. Pozzi, 2018, Vitamins and hormones.

Concurrent inhibition of enzymatic activity and NF-Y-mediated transcription of Topoisomerase-IIα by bis-DemethoxyCurcumin in cancer cells

V. Basile, C. Imbriano, P. Benatti, 2013, Cell Death and Disease.

Inhibition of cell growth by accumulated spermine is associated with a transient alteration of cell cycle progression.

M. G. Monti, L. Pernecco, R. Manfredini, 1996, Life sciences.

Effect of spermine on membrane-associated and membrane-inserted forms of protein kinase C

M. G. Monti, C. Frassineti, G. Marverti, 1993, Molecular and Cellular Biochemistry.

The effect of spermine on calcium requirement for protein kinase C association with phospholipid vesicles.

M. G. Monti, C. Frassineti, G. Marverti, 1995, The international journal of biochemistry & cell biology.

Effect of spermine on association of protein kinase C with phospholipid vesicles.

M. G. Monti, G. Marverti, M. Moruzzi, 1990, Life sciences.

Spermine protects protein kinase C from phospholipid-induced inactivation

M. G. Monti, L. Pernecco, G. Marverti, 1994, Experientia.

Serum Mass Spectrometry Proteomics and Protein Set Identification in Response to FOLFOX-4 in Drug-Resistant Ovarian Carcinoma

Maria Paola Costi, M. Villani, V. Conteduca, 2023, Cancers.

Virtual Screening and X-ray Crystallography Identify Non-Substrate Analog Inhibitors of Flavin-Dependent Thymidylate Synthase.

Maria Paola Costi, T. Blundell, G. Ponterini, 2016, Journal of medicinal chemistry.

Protein–protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase

Maria Paola Costi, Daniela Cardinale, Giambattista Guaitoli, 2011, Proceedings of the National Academy of Sciences.

Inhibitor of ovarian cancer cells growth by virtual screening: a new thiazole derivative targeting human thymidylate synthase.

Maria Paola Costi, R. Stroud, J. Finer-Moore, 2012, Journal of medicinal chemistry.

Ligand-based virtual screening and ADME-tox guided approach to identify triazolo-quinoxalines as folate cycle inhibitors.

Maria Paola Costi, Giambattista Guaitoli, Gabriele Cruciani, 2010, Bioorganic & medicinal chemistry.

Targeting the Interplay of Independent Cellular Pathways and Immunity: A Challenge in Cancer Immunotherapy

S. Santi, A. Caporali, G. Marverti, 2023, Cancers.

Dabrafenib–Panobinostat Salt: Improving the Dissolution Rate and Inhibition of BRAF Melanoma Cells

A. Nangia, S. Rai, G. Marverti, 2023, ACS omega.

Optimization of peptides that target human thymidylate synthase to inhibit ovarian cancer cell growth.

Maria Paola Costi, S. Salvadori, G. Ponterini, 2014, Journal of medicinal chemistry.

Intracellular quantitative detection of human thymidylate synthase engagement with an unconventional inhibitor using tetracysteine-diarsenical-probe technology

Maria Paola Costi, G. Ponterini, R. Guerrini, 2016, Scientific Reports.

Folic Acid–Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting

Maria Paola Costi, F. Spyrakis, G. Ponterini, 2021, Journal of medicinal chemistry.

pH-Promoted Release of a Novel Anti-Tumour Peptide by “Stealth” Liposomes: Effect of Nanocarriers on the Drug Activity in Cis-Platinum Resistant Cancer Cells

Maria Paola Costi, G. Ponterini, E. Leo, 2018, Pharmaceutical Research.

Translational repression of thymidylate synthase by targeting its mRNA

Maria Paola Costi, R. Wade, Divita Garg, 2013, Nucleic acids research.

Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth

E. Giovannetti, G. Peters, R. Wade, 2022, eLife.

Optimization of peptides that target human thymidylate synthase to inhibit ovarian cancer cell growth.

Maria Paola Costi, S. Salvadori, G. Ponterini, 2014, Journal of medicinal chemistry.

Newly synthesized curcumin derivatives: crosstalk between chemico-physical properties and biological activity.

V. Basile, C. Imbriano, M. Saladini, 2011, Journal of medicinal chemistry.

Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer cells.

Maria Paola Costi, S. Piras, P. Corona, 2009, European journal of pharmacology.

Differential induction of spermidine/spermine N1-acetyltransferase in cisplatin-sensitive and -resistant human breast cancer cells by N1, N12-bis(ethyl)spermine.

G. Monti, G. Marverti, M. And, 1999 .