A. Clark

发表

Adipogenesis a Novel Murine Melanocortin 2-Receptor Promoter at Late Stages during A CCAAT/Enhancer-Binding Protein Site at -87 Is Required for the Activation of

L. Noon, A. Clark, P. King, 2006 .

A CCAAT/enhancer-binding protein site at -87 is required for the activation of a novel murine melanocortin 2-receptor promoter at late stages during adipogenesis.

P. O’Shaughnessy, L. Noon, A. Clark, 2006, Endocrinology.

Novel Growth Hormone Receptor Mutation in a Chinese Patient with Laron Syndrome

L. Metherell, M. Savage, A. Clark, 2005, Journal of pediatric endocrinology & metabolism : JPEM.

The insulin‐like growth factor‐I (IGF‐I) gene in individuals born small for gestational age (SGA)

P. Czernichow, M. Savage, J. Léger, 1999, Clinical endocrinology.

Failed export of the adrenocorticotrophin receptor from the endoplasmic reticulum in non-adrenal cells: evidence in support of a requirement for a specific adrenal accessory factor.

L. Hunyady, L. Noon, A. Clark, 2002, The Journal of endocrinology.

Diagnostic and therapeutic advances in growth hormone insensitivity.

L. Metherell, A. David, M. Savage, 2005, Endocrinology and metabolism clinics of North America.

Phenotype: genotype relationships in growth hormone insensitivity syndrome.

M. Preece, S. Amselem, M. Ranke, 1997, The Journal of clinical endocrinology and metabolism.

Effects of insulin-like growth factor I (IGF-I) therapy on body composition and insulin resistance in IGF-I gene deletion.

R. Bergman, M. Savage, A. Clark, 2000, The Journal of clinical endocrinology and metabolism.

Investigation of the role of epigenetic modification of the rat glucokinase gene in fetal programming.

I. Bogdarina, A. Clark, S. Burns, 2004, Life sciences.

Glucocorticoid Effects on the Programming of AT1b Angiotensin Receptor Gene Methylation and Expression in the Rat

A. Haase, I. Bogdarina, S. Langley-Evans, 2010, PloS one.

Differential β‐arrestin binding of AT1 and AT2 angiotensin receptors

L. Hunyady, L. Buday, Gábor Turu, 2006 .

Melanocortin receptor accessory proteins in adrenal disease and obesity

A. Clark, L. Chan, S. Ramachandrappa, 2015, Front. Neurosci..

The cytosolic chaperone Hsc70 promotes traffic to the cell surface of intracellular retained melanocortin-4 receptor mutants.

A. Clark, E. Meimaridou, J. Chapple, 2011, Molecular endocrinology.

60 YEARS OF POMC: The proopiomelanocortin gene: discovery, deletion and disease.

A. Clark, 2016, Journal of molecular endocrinology.

Evidence for a continuum of genetic, phenotypic, and biochemical abnormalities in children with growth hormone insensitivity.

V. Hwa, L. Metherell, A. David, 2011, Endocrine reviews.

Fetal programming of perivenous glucose uptake reveals a regulatory mechanism governing hepatic glucose output during refeeding.

G. Hitman, I. Bogdarina, R. Iles, 2003, Diabetes.

Spontaneous growth hormone secretory characteristics in children with partial growth hormone insensitivity

L. Metherell, M. Savage, K. Albertsson-Wikland, 2002, Clinical endocrinology.

Ligand-specific conformational change of the G-protein–coupled receptor ALX/FPR2 determines proresolving functional responses

M. Perretti, R. Flower, Trinidad Montero-Melendez, 2013, Proceedings of the National Academy of Sciences.

Network of European Studies of Genes in Growth (NESTEGG)

H. Wollmann, M. Savage, M. Ranke, 2009, Hormone Research in Paediatrics.

Pathophysiology of melanocortin receptors and their accessory proteins.

T. Novoselova, A. Clark, L. Chan, 2018, Best practice & research. Clinical endocrinology & metabolism.

Melanocortin 4 receptor becomes an ACTH receptor by coexpression of melanocortin receptor accessory protein 2.

J. Cerdá-Reverter, A. Clark, E. Meimaridou, 2013, Molecular endocrinology.

Inherited ACTH insensitivity illuminates the mechanisms of ACTH action

L. Metherell, M. Cheetham, A. Huebner, 2005, Trends in Endocrinology & Metabolism.

Tall stature in familial glucocorticoid deficiency

P. Clayton, L. Metherell, M. Savage, 2000, Clinical endocrinology.

Update in growth hormone insensitivity syndrome

M. Savage, A. Clark, J. Blair, 2002 .

Characterization of the angiotensin (AT1b) receptor promoter and its regulation by glucocorticoids

I. Bogdarina, A. Clark, P. King, 2009, Journal of molecular endocrinology.

Effects of recombinant human insulin-like growth factor I (IGF-I) therapy on the growth hormone-IGF system of a patient with a partial IGF-I gene deletion.

P. Hindmarsh, R. Baxter, Y. Hansson, 1999, The Journal of clinical endocrinology and metabolism.

Impaired desensitization of a mutant adrenocorticotropin receptor associated with apparent constitutive activity.

L. Hunyady, M. Thorner, A. Baig, 2002, Molecular endocrinology.

MCM4 mutation causes adrenal failure, short stature, and natural killer cell deficiency in humans.

L. Metherell, L. Guasti, J. Schimenti, 2012, The Journal of clinical investigation.

Role of the Proline-rich Domain of Dynamin-2 and Its Interactions with Src Homology 3 Domains during Endocytosis of the AT1 Angiotensin Receptor*

L. Hunyady, P. McPherson, K. Catt, 2002, The Journal of Biological Chemistry.

TPIT mutations are associated with early-onset, but not late-onset isolated ACTH deficiency.

M. Dattani, I. Farooqi, P. Clayton, 2004, European journal of endocrinology.

Loss of Function of the Melanocortin 2 Receptor Accessory Protein 2 Is Associated with Mammalian Obesity

M. Ridderstråle, J. Hirschhorn, S. O’Rahilly, 2013, Science.

Endocrine assessment, molecular characterization and treatment of growth hormone insensitivity disorders

L. Metherell, A. David, M. Savage, 2006, Nature Clinical Practice Endocrinology &Metabolism.

Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene.

M. Savage, A. Clark, C. Camacho‐Hübner, 1996, The New England journal of medicine.

Phenotypic aspects of growth hormone- and IGF-I-resistant syndromes.

L. Metherell, A. David, M. Savage, 2009, Endocrine development.

IGF-I Deficiency: Lessons from Human Mutations

J. Wit, L. Metherell, A. David, 2005 .

Insulin-Like Growth Factor (IGF)-I Gene Deletion

M. Savage, A. Clark, C. Camacho‐Hübner, 2002, Reviews in Endocrine and Metabolic Disorders.

Growth Hormone Insensitivity

S. Amselem, M. Savage, A. Clark, 2004 .

Insulin-like growth factor-I deficiency caused by a partial deletion of the IGF-I gene: Effects of rhIGFmi therapy

M. Savage, A. Clark, C. Camacho‐Hübner, 1999 .

Relationship between phenotype and genotype in growth hormone insensitivity syndrome

S. Amselem, A. Clark, M. Savage, 1999, Acta paediatrica (Oslo, Norway : 1992). Supplement.

The Broad Spectrum of Inherited Growth Hormone Insensitivity Syndrome

M. Savage, A. Clark, L. Johnston, 1998, Trends in Endocrinology & Metabolism.

The molecular pathology of pituitary hormone deficiency and resistance.

A. Clark, A. Weber, K. Woods, 1995, Bailliere's clinical endocrinology and metabolism.

Defects of the growth hormone receptor and their clinical implications.

S. Amselem, M. Savage, A. Clark, 1999, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Acid-Labile Subunit Deficiency and Growth Failure: Description of Two Novel Cases

L. Metherell, A. David, M. Savage, 2010, Hormone Research in Paediatrics.

GH responsiveness in a large multinational cohort of SGA children with short stature (NESTEGG) is related to the exon 3 GHR polymorphism

M. Savage, M. Ranke, M. Tauber, 2007, Clinical endocrinology.

Angiotensin II-induced expression of brain-derived neurotrophic factor in human and rat adrenocortical cells.

L. Hunyady, L. Buday, T. Chaplin, 2010, Endocrinology.

The comparative endocrinology of appetite

Julian R. E. Davis, A. Clark, 2007 .

Missense mutations in the melanocortin 2 receptor accessory protein that lead to late onset familial glucocorticoid deficiency type 2.

F. Keleştimur, L. Metherell, T. Chung, 2010, The Journal of clinical endocrinology and metabolism.

The genetics of ACTH resistance syndromes.

L. Metherell, A. Clark, L. Chan, 2006, Best practice & research. Clinical endocrinology & metabolism.

Polymorphism in the IGF-I gene: clinical relevance for short children born small for gestational age (SGA).

C. V. van Duijn, M. Savage, A. Hokken-Koelega, 2002, The Journal of clinical endocrinology and metabolism.

Growth Abnormalities Associated with Adrenal Disorders and Their Management

M. Savage, J. Chaussain, A. Lienhardt, 2002, Hormone Research in Paediatrics.

AT1 receptor blocker-insensitive mutant AT1A angiotensin receptors reveal the presence of G protein-independent signaling in C9 cells.

L. Hunyady, P. Várnai, Gábor Turu, 2007, Biochemical pharmacology.

Analysis of the intracellular signalling domain of the human growth hormone receptor in children with idiopathic short stature

M. Savage, F. Pashankar, A. Clark, 2000, Clinical endocrinology.

Growth hormone (GH) insensitivity syndrome due to a GH receptor truncated after Box1, resulting in isolated failure of STAT 5 signal transduction.

L. Metherell, M. Savage, M. Bidlingmaier, 2004, The Journal of clinical endocrinology and metabolism.

Phenotypic characteristics of familial glucocorticoid deficiency (FGD) type 1 and 2

L. Metherell, T. Chung, A. Clark, 2010, Clinical endocrinology.

ACTH signalling and adrenal development: lessons from mouse models

L. Metherell, L. Guasti, T. Novoselova, 2019, Endocrine connections.

Growth Hormone Insensitivity: Pathophysiology, Diagnosis, Clinical Variation and Future Perspectives

L. Metherell, M. Savage, C. Burren, 2001, Hormone Research in Paediatrics.

The melanocortin 2 receptor accessory protein exists as a homodimer and is essential for the function of the melanocortin 2 receptor in the mouse y1 cell line.

M. Elphick, T. Webb, M. Cheetham, 2008, Endocrinology.

Nonclassic lipoid congenital adrenal hyperplasia masquerading as familial glucocorticoid deficiency.

D. Berney, M. Racine, G. Nürnberg, 2009, The Journal of clinical endocrinology and metabolism.

Deficiency of ALADIN Impairs Redox Homeostasis in Human Adrenal Cells and Inhibits Steroidogenesis

L. Metherell, H. Storr, A. Clark, 2013, Endocrinology.

Mechanisms and functions of AT1 angiotensin receptor internalization

L. Hunyady, K. Catt, A. Clark, 2000, Regulatory Peptides.

d3‐GHR genotype does not explain heterogeneity in GH responsiveness in hypopituitary adults

W. Drake, L. Metherell, S. Akker, 2009, Clinical endocrinology.

Bioluminescence Resonance Energy Transfer Reveals the Adrenocorticotropin (ACTH)-Induced Conformational Change of the Activated ACTH Receptor Complex in Living Cells

T. Chung, A. Clark, L. Szidonya, 2010, Endocrinology.

ACTH resistance: genes and mechanisms.

L. Metherell, A. Clark, E. Meimaridou, 2013, Endocrine development.

Severe loss-of-function mutations in the adrenocorticotropin receptor (ACTHR, MC2R) can be found in patients diagnosed with salt-losing adrenal hypoplasia

M. Dattani, P. Hindmarsh, C. Brain, 2007, Clinical endocrinology.

A homozygous splice site mutation affecting the intracellular domain of the growth hormone (GH) receptor resulting in Laron syndrome with elevated GH-binding protein.

A. Clark, M. Savage, M. Postel-Vinay, 1996, The Journal of clinical endocrinology and metabolism.

The E3 ubiquitin ligase Mahogunin ubiquitinates the melanocortin 2 receptor.

L. Guasti, A. Clark, S. Cooray, 2011, Endocrinology.

Familial glucocorticoid deficiency: New genes and mechanisms

Claire Hughes, L. Metherell, L. Guasti, 2013, Molecular and Cellular Endocrinology.

Melanocortin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

R. Cone, J. Wikberg, V. Hruby, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Distinct melanocortin 2 receptor accessory protein domains are required for melanocortin 2 receptor interaction and promotion of receptor trafficking.

T. Webb, M. Cheetham, A. Clark, 2009, Endocrinology.

Genetic Analysis of Pediatric Primary Adrenal Insufficiency of Unknown Etiology: 25 Years’ Experience in the UK

M. Dattani, P. Hindmarsh, N. S. Thomas, 2021, Journal of the Endocrine Society.

Isolated Addison's disease is unlikely to be caused by mutations in MC2R, MRAP or STAR, three genes responsible for familial glucocorticoid deficiency

S. Pearce, L. Metherell, R. Dias, 2010, European journal of endocrinology.

Whole-Exome Sequencing in the Differential Diagnosis of Primary Adrenal Insufficiency in Children

L. Metherell, T. Novoselova, D. Campbell, 2015, Front. Endocrinol..

Thioredoxin Reductase 2 (TXNRD2) Mutation Associated With Familial Glucocorticoid Deficiency (FGD)

L. Metherell, H. Storr, M. Savage, 2014, The Journal of clinical endocrinology and metabolism.

Mutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2

F. Rüschendorf, C. Becker, P. Nürnberg, 2005, Nature Genetics.

Triple A syndrome is caused by mutations in AAAS, a new WD-repeat protein gene.

S. Hennig, S. Sperling, A. Huebner, 2001, Human molecular genetics.

Mutations in Nicotinamide Nucleotide Transhydrogenase (NNT) cause familial glucocorticoid deficiency

F. Wagner, P. Frommolt, P. Nürnberg, 2012, Nature Genetics.

The majority of adrenocorticotropin receptor (melanocortin 2 receptor) mutations found in familial glucocorticoid deficiency type 1 lead to defective trafficking of the receptor to the cell surface.

T. Webb, L. Metherell, T. Chung, 2008, The Journal of clinical endocrinology and metabolism.

A novel variant of familial glucocorticoid deficiency prevalent among the Irish Traveler population.

P. Hindmarsh, S. Lynch, C. Costigan, 2008, The Journal of clinical endocrinology and metabolism.

Adrenocorticotropin resistance syndromes.

L. Metherell, H. Storr, A. Clark, 2008, Endocrine development.

Linkage of one gene for familial glucocorticoid deficiency type 2 (FGD2) to chromosome 8q and further evidence of heterogeneity

E. Génin, A. Huebner, D. Naville, 2002, Human Genetics.

Familial Glucocorticoid Deficiency: Advances in the Molecular Understanding of ACTH Action

L. Metherell, A. Clark, L. Chan, 2007, Hormone Research in Paediatrics.

An Atypical Case of Familial Glucocorticoid Deficiency without Pigmentation Caused by Coexistent Homozygous Mutations in MC2R (T152K) and MC1R (R160W)

L. Metherell, A. Bereket, S. Turan, 2011, The Journal of clinical endocrinology and metabolism.

Deficiency of ferritin heavy-chain nuclear import in triple a syndrome implies nuclear oxidative damage as the primary disease mechanism.

H. Storr, K. Koehler, A. Huebner, 2009, Molecular endocrinology.

MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family

M. Elphick, T. Webb, L. Metherell, 2009, Proceedings of the National Academy of Sciences.

Effects of melanocortins on adrenal gland physiology.

L. Metherell, A. Clark, L. Chan, 2011, European journal of pharmacology.

Homozygous nonsense and frameshift mutations of the ACTH receptor in children with familial glucocorticoid deficiency (FGD) are not associated with long-term mineralocorticoid deficiency

H. Krude, L. Metherell, M. Savage, 2009, Clinical endocrinology.

A Peroxisome Proliferator-response Element in the Murine mc2-r Promoter Regulates Its Transcriptional Activation during Differentiation of 3T3-L1 Adipocytes*

L. Noon, A. Clark, P. King, 2004, Journal of Biological Chemistry.

Familial Isolated Primary Pigmented Nodular Adrenocortical Disease Associated with a Novel Low Penetrance PRKAR1A Gene Splice Site Mutation

K. Main, L. Metherell, H. Storr, 2010, Hormone Research in Paediatrics.

Molecular Pathology of Corticotroph Function

A. Clark, F. Swords, 2001 .

Mechanisms of adrenocorticotropin-induced activation of extracellularly regulated kinase 1/2 mitogen-activated protein kinase in the human H295R adrenal cell line.

K. Chu, A. Clark, P. King, 2008, Endocrinology.

Genetic factors contributing to birth weight

M. Savage, L B Johnston, A J L Clark, 2002, Archives of disease in childhood. Fetal and neonatal edition.

Multiple segmental uniparental disomy associated with abnormal DNA methylation of imprinted Loci in silver-russell syndrome.

J. Cazier, I. Bogdarina, A. Hokken-Koelega, 2012, The Journal of clinical endocrinology and metabolism.

Melanocortin receptor accessory proteins in adrenal gland physiology and beyond.

T. Novoselova, D. Campbell, A. Clark, 2013, The Journal of endocrinology.

Loss of the C terminus of melanocortin receptor 2 (MC2R) results in impaired cell surface expression and ACTH insensitivity.

C. Flück, A. Pandey, M. Fernández-Cancio, 2010, The Journal of clinical endocrinology and metabolism.

Minireview: the melanocortin 2 receptor accessory proteins.

T. Webb, A. Clark, 2010, Molecular endocrinology.

The genetics of familial glucocorticoid deficiency.

L. Metherell, T. Chung, A. Clark, 2009, Best practice & research. Clinical endocrinology & metabolism.

Linkage of the gene for the triple A syndrome to chromosome 12q13 near the type II keratin gene cluster.

H J Dean, T. Wienker, D. Easton, 1996, Human molecular genetics.

Molecular insights into inherited ACTH resistance syndromes

A. Clark, A. Weber, 1994, Trends in Endocrinology & Metabolism.

DNA Methylation and Silencing of Gene Expression

J. Newell-Price, John Newell-Price, Adrian J. L. Clark, 2000, Trends in Endocrinology & Metabolism.

Melanocortin receptors and their accessory proteins

A. Clark, S. Cooray, 2011, Molecular and Cellular Endocrinology.

Triple a Syndrome—Clinical Aspects and Molecular Genetics

A. Huebner, F. Ozkinay, A. Huebner, 2000, Endocrine research.

The melanocortin receptors and their accessory proteins

A. Clark, L. Chan, S. Ramachandrappa, 2011, Front. Endocrin..

eview elanocortin receptors and their accessory proteins

A. Clark, adani N. Cooray, 2010 .

Mechanisms of Disease: the adrenocorticotropin receptor and disease

L. Metherell, A. Clark, 2006, Nature Clinical Practice Endocrinology &Metabolism.

Constitutive activation of the human ACTH receptor resulting from a synergistic interaction between two naturally occurring missense mutations in the MC2R gene

L. Noon, A. Clark, P. King, 2004, Molecular and Cellular Endocrinology.

An intronic growth hormone receptor mutation causing activation of a pseudoexon is associated with a broad spectrum of growth hormone insensitivity phenotypes.

P. Clayton, L. Metherell, A. David, 2007, The Journal of clinical endocrinology and metabolism.

Pseudoexon activation as a novel mechanism for disease resulting in atypical growth-hormone insensitivity.

M. Caulfield, S. Chew, L. Metherell, 2001, American journal of human genetics.

Epigenetic Modification of the Renin-Angiotensin System in the Fetal Programming of Hypertension

I. Bogdarina, A. Clark, P. King, 2007, Circulation research.

Deficiency of Ferritin Heavy-Chain Nuclear Import in Triple A Syndrome Implies Nuclear Oxidative Damage as the Primary Disease Mechanism

H. Storr, K. Koehler, A. Huebner, 2009 .

ACTH insensitivity syndromes

L. Metherell, A. Clark, C. Hughes, 2009 .

AGONIST ACTIVATED ADRENOCORTICOTROPIN RECEPTOR INTERNALIZES VIA A CLATHRIN-MEDIATED G PROTEIN RECEPTOR KINASE DEPENDENT MECHANISM

L. Hunyady, A. Baig, A. Clark, 2002, Endocrine research.

A novel liver specific isoform of the rat LAR transcript is expressed as a truncated isoform encoded from a 5'UTR located within intron 11

Simon J. M. Welham, A. Salter, A. Clark, 2009, BMC Molecular Biology.

Accessory proteins are vital for the functional expression of certain G protein-coupled receptors

T. Webb, L. Metherell, A. Clark, 2009, Molecular and Cellular Endocrinology.

Association Analysis of Ten Candidate Genes in a Large Multinational Cohort of Small for Gestational Age Children and Children with Idiopathic Short Stature (NESTEGG study)

C. V. van Duijn, H. Wallaschofski, H. Wollmann, 2013, Hormone Research in Paediatrics.

Defects of the growth hormonereceptor and their clinical implications

S. Amselem, M. Savage, A. Clark, 1999 .

Idiopathic short stature: will genetics influence the choice between GH and IGF-I therapy?

V. Hwa, L. Metherell, A. David, 2007, European journal of endocrinology.

Adrenal Disease in Childhood: Clinical and Molecular Aspects

I. Hughes, A. Clark, 2000 .

Identification of a novel specific small-molecule melanocortin-2-receptor antagonist

J. Jerman, A. Clark, Debra L. Taylor, 2022, Endocrine connections.

Differential beta-arrestin binding of AT1 and AT2 angiotensin receptors.

L. Hunyady, L. Buday, Gábor Turu, 2006, FEBS letters.

Structural determinants of agonist-induced signaling and regulation of the angiotensin AT1 receptor

B. H. Shah, L. Hunyady, K. Catt, 2004, Molecular and Cellular Endocrinology.

Identification of a novel melanocortin 2 receptor splice variant in murine adipocytes: implications for post-transcriptional control of expression during adipogenesis.

P. O’Shaughnessy, L. Noon, A. Clark, 2006, Journal of molecular endocrinology.

Identification and characterisation of a novel GHR defect disrupting the polypyrimidine tract and resulting in GH insensitivity

L. Metherell, A. David, M. Savage, 2010, European journal of endocrinology.

Endocytosis of the AT1A angiotensin receptor is independent of ubiquitylation of its cytoplasmic serine/threonine-rich region.

L. Hunyady, P. Várnai, K. Catt, 2003, The international journal of biochemistry & cell biology.

Contents Vol. 80, 2013

P. Czernichow, G. Rappold, H. Wallaschofski, 2014, Hormone Research in Paediatrics.

Genome-Wide Methylation and Gene Expression Changes in Newborn Rats following Maternal Protein Restriction and Reversal by Folic Acid

E. Stupka, I. Bogdarina, S. Langley-Evans, 2013, PloS one.

Loss of Mrap2 is associated with Sim1 deficiency and increased circulating cholesterol

C. Lelliott, S. O’Rahilly, D. Logan, 2016, The Journal of endocrinology.

Melanocortin Type 3 Receptor on Murine POMC Gene-Derived Peptides Activate

M. Perretti, R. Flower, L. Gibbs, 1999 .

The ACTH Receptor and Its Mutations

A. Clark, P. King, 2003 .

Melanocortin receptors in GtoPdb v.2021.3

R. Cone, V. Hruby, H. Schiöth, 2021, IUPHAR/BPS Guide to Pharmacology CITE.

Association between insulin-like growth factor I (IGF-I) polymorphisms, circulating IGF-I, and pre- and postnatal growth in two European small for gestational age populations.

P. Czernichow, M. Savage, J. Dahlgren, 2003, The Journal of clinical endocrinology and metabolism.

Neonatal presentation of familial glucocorticoid deficiency resulting from a novel splice mutation in the melanocortin 2 receptor accessory protein

L. Metherell, A. David, A. Clark, 2011, European journal of endocrinology.

Repair of aberrant splicing in growth hormone receptor by antisense oligonucleotides targeting the splice sites of a pseudoexon.

U. Srirangalingam, L. Metherell, A. David, 2010, The Journal of clinical endocrinology and metabolism.

A 36 residues insertion in the dimerization domain of the growth hormone receptor results in defective trafficking rather than impaired signaling.

L. Metherell, M. Savage, R. Ross, 2006, The Journal of endocrinology.

Gastric Inhibitory Polypeptide Receptor (GIPR) Expression in Cushing's Disease

J. Arola, A. Clark, S. Aylwin, 2004 .

MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation

L. Metherell, L. Guasti, T. Novoselova, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Basic and Clinical Aspects of Immunity to Insulin

A. Clark, 1982 .

Desensitization of the Y1 Cell Adrenocorticotropin Receptor

L. Hunyady, A. Baig, A. Clark, 2001, The Journal of Biological Chemistry.

60 YEARS OF POMC: Biosynthesis, trafficking, and secretion of pro-opiomelanocortin-derived peptides.

Y. Loh, N. Cawley, P. Lowry, 2016, Journal of molecular endocrinology.

60 yEars Of POMC Regulation of feeding and energy homeostasis by α -MSH

Masoud Ghamari-Langroudi, R. Cone, Erica J P Anderson, 2016 .

Functional consequence of a novel Y129C mutation in a patient with two contradictory melanocortin-2-receptor mutations

L. Metherell, T. Chung, A. Clark, 2009, European journal of endocrinology.

Clinical and biological phenotype of a patient with familial glucocorticoid deficiency type 2 caused by a mutation of melanocortin 2 receptor accessory protein.

L. Metherell, M. Maes, V. Beauloye, 2007, European journal of endocrinology.

Insulin-like growth factor-I deficiency caused by a partial deletion of the IGF-I gene: effects of rhIGF-I therapy.

A. Clark, C. Camacho‐Hübner, M. Savage, 1999, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Essential hypertension in African Caribbeans associates with a variant of the beta2-adrenoceptor.

M. Caulfield, A. Clark, P. Kotanko, 1997, Hypertension.

Linkage of the angiotensinogen gene to essential hypertension.

P. Munroe, M. Caulfield, M. Farrall, 1994, The New England journal of medicine.

60 YEARS OF POMC: POMC: the consummate peptide hormone precursor.

P. Lowry, A. Clark, 2016, Journal of molecular endocrinology.

Localisation of the melanocortin-2-receptor and its accessory proteins in the developing and adult adrenal gland

L. Guasti, A. Clark, P. King, 2011, Journal of molecular endocrinology.

Expression, Desensitization, and Internalization of the ACTH Receptor (MC2R)

L. Hunyady, A. Baig, L. Noon, 2003, Annals of the New York Academy of Sciences.

developing and adult adrenal gland

L. Guasti, A. Clark, P. King, 2011 .