P. King

发表

Adipogenesis a Novel Murine Melanocortin 2-Receptor Promoter at Late Stages during A CCAAT/Enhancer-Binding Protein Site at -87 Is Required for the Activation of

L. Noon, A. Clark, P. King, 2006 .

A CCAAT/enhancer-binding protein site at -87 is required for the activation of a novel murine melanocortin 2-receptor promoter at late stages during adipogenesis.

P. O’Shaughnessy, L. Noon, A. Clark, 2006, Endocrinology.

The RNA-binding protein HuD is required for GAP-43 mRNA stability, GAP-43 gene expression, and PKC-dependent neurite outgrowth in PC12 cells.

N. Perrone-Bizzozero, A. Beckel-Mitchener, K. Anderson, 2000, Molecular biology of the cell.

Oncometabolite induced primary cilia loss in pheochromocytoma

Tyson V. Sharp, C. Thompson, M. Knight, 2018, Endocrine-related cancer.

Sodium Butyrate-Mediated Sp3 Acetylation Represses Human Insulin-Like Growth Factor Binding Protein-3 Expression in Intestinal Epithelial Cells

P. Mulligan, I. Sanderson, P. King, 2006, Journal of pediatric gastroenterology and nutrition.

FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development

L. Guasti, T. McKay, R. Grose, 2013, Molecular and Cellular Endocrinology.

Failed export of the adrenocorticotrophin receptor from the endoplasmic reticulum in non-adrenal cells: evidence in support of a requirement for a specific adrenal accessory factor.

L. Hunyady, L. Noon, A. Clark, 2002, The Journal of endocrinology.

Glial Cells Missing 1 Regulates Equine Chorionic Gonadotrophin Beta Subunit via Binding to the Proximal Promoter

Judith E. Cartwright, R. Fowkes, P. King, 2018, Frontiers in Endocrinology.

Desensitization of the Y1 Cell Adrenocorticotropin Receptor

L. Hunyady, A. Baig, A. Clark, 2001, The Journal of Biological Chemistry.

Regulation of Human Glycoprotein Hormone α-Subunit Gene Transcription in LβT2 Gonadotropes by Protein Kinase C and Extracellular Signal-Regulated Kinase 1/21

J. Burrin, R. Fowkes, P. King, 2002 .

Characterization of the angiotensin (AT1b) receptor promoter and its regulation by glucocorticoids

I. Bogdarina, A. Clark, P. King, 2009, Journal of molecular endocrinology.

Sonic hedgehog signaling during adrenal development

E. Laufer, P. King, A. Vortkamp, 2012, Molecular and Cellular Endocrinology.

AGONIST ACTIVATED ADRENOCORTICOTROPIN RECEPTOR INTERNALIZES VIA A CLATHRIN-MEDIATED G PROTEIN RECEPTOR KINASE DEPENDENT MECHANISM

L. Hunyady, A. Baig, A. Clark, 2002, Endocrine research.

Impaired desensitization of a mutant adrenocorticotropin receptor associated with apparent constitutive activity.

L. Hunyady, M. Thorner, A. Baig, 2002, Molecular endocrinology.

Kisspeptin Is a Novel Regulator of Human Fetal Adrenocortical Development and Function: A Finding With Important Implications for the Human Fetoplacental Unit

L. Dunkel, L. Guasti, H. Storr, 2017, The Journal of clinical endocrinology and metabolism.

1 ! 2 ! KISSPEPTIN IS A NOVEL REGULATOR OF HUMAN FETAL ADRENOCORTICAL 3 ! DEVELOPMENT AND FUNCTION – A FINDING WITH IMPORTANT IMPLICATIONS FOR 4 ! THE HUMAN FETO-PLACENTAL UNIT 5 ! 6 !

L. Dunkel, L. Guasti, W. Dhillo, 2017 .

MCM4 mutation causes adrenal failure, short stature, and natural killer cell deficiency in humans.

L. Metherell, L. Guasti, J. Schimenti, 2012, The Journal of clinical investigation.

The human fetal adrenal produces cortisol but no detectable aldosterone throughout the second trimester

M. Simard, P. Filis, P. Fowler, 2018, BMC Medicine.

Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages

E. Laufer, P. King, Alex Paul, 2009, Proceedings of the National Academy of Sciences.

Effects of ACTH and expression of the melanocortin-2 receptor in the neonatal mouse testis.

P. O’Shaughnessy, P. King, H. Johnston, 2007, Reproduction.

Dlk1 up-regulates Gli1 expression in male rat adrenal capsule cells through the activation of β1 integrin and ERK1/2.

L. Guasti, P. King, Z. Banu, 2013, Endocrinology.

ACTH signalling and adrenal development: lessons from mouse models

L. Metherell, L. Guasti, T. Novoselova, 2019, Endocrine connections.

Expression of guanylyl cyclase-B (GC-B/NPR2) receptors in normal human fetal pituitaries and human pituitary adenomas implicates a role for C-type natriuretic peptide.

I. McGonnell, M. Korbonits, A. Mcneilly, 2012, Endocrine-Related Cancer.

Modeling Congenital Adrenal Hyperplasia and Testing Interventions for Adrenal Insufficiency Using Donor-Specific Reprogrammed Cells

U. Srirangalingam, S. Bornstein, W. Drake, 2018, Cell reports.

Absence of pituitary adenylate cyclase-activating polypeptide-stimulated transcription of the human glycoprotein alpha-subunit gene in LbetaT2 gonadotrophs reveals disrupted cAMP-mediated gene transcription.

J. Burrin, J. Sosabowski, R. Fowkes, 2003, Journal of molecular endocrinology.

Interaction of the melanocortin 2 receptor with nucleoporin 50: evidence for a novel pathway between a G‐protein‐coupled receptor and the nucleus

H. Storr, A. Clark, M. Doufexis, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Familial glucocorticoid deficiency: New genes and mechanisms

Claire Hughes, L. Metherell, L. Guasti, 2013, Molecular and Cellular Endocrinology.

Adrenocortical development, maintenance, and disease.

Claire Hughes, L. Metherell, L. Guasti, 2013, Current topics in developmental biology.

Localization of Sonic hedgehog secreting and receiving cells in the developing and adult rat adrenal cortex

E. Laufer, L. Guasti, P. King, 2011, Molecular and Cellular Endocrinology.

Expression of Cyp21a1 and Cyp11b1 in the fetal mouse testis.

P. O’Shaughnessy, P. King, L. Hu, 2007, Reproduction.

Mutations in Nicotinamide Nucleotide Transhydrogenase (NNT) cause familial glucocorticoid deficiency

F. Wagner, P. Frommolt, P. Nürnberg, 2012, Nature Genetics.

The majority of adrenocorticotropin receptor (melanocortin 2 receptor) mutations found in familial glucocorticoid deficiency type 1 lead to defective trafficking of the receptor to the cell surface.

T. Webb, L. Metherell, T. Chung, 2008, The Journal of clinical endocrinology and metabolism.

A Peroxisome Proliferator-response Element in the Murine mc2-r Promoter Regulates Its Transcriptional Activation during Differentiation of 3T3-L1 Adipocytes*

L. Noon, A. Clark, P. King, 2004, Journal of Biological Chemistry.

Hedgehog signalling in endocrine development and disease.

E. Laufer, L. Guasti, P. King, 2008, The Journal of endocrinology.

Steroidogenic factor-1 and the gonadotrope-specific element enhance basal and pituitary adenylate cyclase-activating polypeptide-stimulated transcription of the human glycoprotein hormone alpha-subunit gene in gonadotropes.

S. Aylwin, H. Ingraham, J. Burrin, 2003, Molecular endocrinology.

Mechanisms of adrenocorticotropin-induced activation of extracellularly regulated kinase 1/2 mitogen-activated protein kinase in the human H295R adrenal cell line.

K. Chu, A. Clark, P. King, 2008, Endocrinology.

DNA Methylation and Silencing of Gene Expression

J. Newell-Price, John Newell-Price, Adrian J. L. Clark, 2000, Trends in Endocrinology & Metabolism.

New Directions for the Treatment of Adrenal Insufficiency

L. Guasti, P. King, G. Ruiz-Babot, 2015, Front. Endocrinol..

Characterization of Aryl Hydrocarbon Receptor Interacting Protein (AIP) Mutations in Familial Isolated Pituitary Adenoma Families

U. Srirangalingam, S. Ellard, M. Korbonits, 2010, Human mutation.

Constitutive activation of the human ACTH receptor resulting from a synergistic interaction between two naturally occurring missense mutations in the MC2R gene

L. Noon, A. Clark, P. King, 2004, Molecular and Cellular Endocrinology.

BBS-induced ciliary defect enhances adipogenesis, causing paradoxical higher-insulin sensitivity, glucose usage, and decreased inflammatory response.

N. Petrovsky, H. Dollfus, N. Messaddeq, 2012, Cell metabolism.

Epigenetic Modification of the Renin-Angiotensin System in the Fetal Programming of Hypertension

I. Bogdarina, A. Clark, P. King, 2007, Circulation research.

The CpG island promoter of the human proopiomelanocortin gene is methylated in nonexpressing normal tissue and tumors and represses expression.

J. Newell-Price, A. Clark, P. King, 2001, Molecular endocrinology.

Expression of Cyp 21 a 1 and Cyp 11 b 1 in the fetal mouse testis

P. O’Shaughnessy, P. King, L. Hu, 2007 .

DLK1/PREF1 marks a novel cell population in the human adrenal cortex

W. Drake, L. Guasti, C. Gomez-Sanchez, 2019, The Journal of Steroid Biochemistry and Molecular Biology.

The role of ghrelin and ghrelin-receptor gene variants and promoter activity in type 2 diabetes.

C. Lecoeur, M. Korbonits, A. Grossman, 2009, European journal of endocrinology.

Identification of a novel melanocortin 2 receptor splice variant in murine adipocytes: implications for post-transcriptional control of expression during adipogenesis.

P. O’Shaughnessy, L. Noon, A. Clark, 2006, Journal of molecular endocrinology.

Somatic mutations of CADM1 in aldosterone-producing adenomas and gap junction-dependent regulation of aldosterone production

C. Mein, W. Drake, A. David, 2023, Nature Genetics.

The ACTH Receptor and Its Mutations

A. Clark, P. King, 2003 .

MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation

L. Metherell, L. Guasti, T. Novoselova, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

TUMOUR-DERIVED HUMAN ADRENOCORTICAL CELLS EXPRESS β-ADRENERGIC RECEPTORS: STEROIDOGENIC EFFECTS OF β-ADRENERGIC INPUT

O. Kosti, P. King, J. Hinson, 2002 .

Regulation of human glycoprotein hormone alpha-subunit gene transcription in LbetaT2 gonadotropes by protein kinase C and extracellular signal-regulated kinase 1/2.

J. Burrin, R. Fowkes, P. King, 2002, Biology of reproduction.

Shh signaling regulates adrenocortical development and identifies novel progenitors of steroidogenic lineages

E. Laufer, P. King, Alex Paul, 2009 .

University of Huddersfield Repository Epigenetic modification of the renin-angiotensin system in the fetal programming of hypertension

A. Clark, I. Bogdarina, P. King, 2022 .

Epigenetic Modification of the Renin-Angiotensin System in the Fetal Programming of Print

Simon J. M. Welham, A. Clark, I. Bogdarina, 2007 .

Localisation of the melanocortin-2-receptor and its accessory proteins in the developing and adult adrenal gland

L. Guasti, A. Clark, P. King, 2011, Journal of molecular endocrinology.

Expression, Desensitization, and Internalization of the ACTH Receptor (MC2R)

L. Hunyady, A. Baig, L. Noon, 2003, Annals of the New York Academy of Sciences.