I. Kasheverov

发表

Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an α-conotoxin PnIA variant

D. Bertrand, T. Sixma, A. Smit, 2005, Nature Structural &Molecular Biology.

Marine Origin Ligands of Nicotinic Receptors: Low Molecular Compounds, Peptides and Proteins for Fundamental Research and Practical Applications

Y. Utkin, V. Tsetlin, I. Shelukhina, 2022, Biomolecules.

Toxins' classification through Raman spectroscopy with principal component analysis.

V. Tsetlin, K. Prokhorov, I. Kasheverov, 2022, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

Interaction of α9α10 Nicotinic Receptors With Peptides and Proteins From Animal Venoms

A. Nicke, V. Tsetlin, I. Shelukhina, 2021, Frontiers in Cellular Neuroscience.

Oligoarginine Peptides, a New Family of Nicotinic Acetylcholine Receptor Inhibitors

R. Katsarava, N. Zavradashvili, V. Tsetlin, 2019, Molecular Pharmacology.

Species specificity of rat and human α7 nicotinic acetylcholine receptors towards different classes of peptide and protein antagonists

V. Tsetlin, I. Kasheverov, D. Kudryavtsev, 2018, Neuropharmacology.

Orthosteric and/or Allosteric Binding of α-Conotoxins to Nicotinic Acetylcholine Receptors and Their Models

V. Tsetlin, S. Tzartos, I. Kasheverov, 2018, Marine drugs.

High-Affinity α-Conotoxin PnIA Analogs Designed on the Basis of the Protein Surface Topography Method

R. Efremov, V. Tsetlin, I. Shelukhina, 2016, Scientific Reports.

Nonconventional three-finger toxin BMLCL from krait Bungarus multicinctus venom with high affinity interacts with nicotinic acetylcholine receptors

D. V. Kuznetsov, Hoang Ngoc Anh, T. Andreeva, 2015, Doklady Biochemistry and Biophysics.

Rational design of new ligands for nicotinic receptors on the basis of α-conotoxin PnIA

R. Efremov, V. Tsetlin, A. Chugunov, 2015, Doklady Biochemistry and Biophysics.

Interaction of α‐conotoxin ImII and its analogs with nicotinic receptors and acetylcholine‐binding proteins: additional binding sites on Torpedo receptor

D. Bertrand, T. Sixma, A. Smit, 2009, Journal of neurochemistry.

[Efficient synthesis of natural alpha-conotoxins and their analogs].

V. Ivanov, V. Tsetlin, I. Kasheverov, 2001, Bioorganicheskaia khimiia.

An Efficient Synthetic Scheme for Natural α-Conotoxins and Their Analogues

V. Ivanov, Y. Utkin, V. Tsetlin, 2001, Russian Journal of Bioorganic Chemistry.

Naturally Occurring Disulfide-bound Dimers of Three-fingered Toxins

D. Bertrand, R. Hogg, M. Serebryakova, 2008, Journal of Biological Chemistry.

Snake Venom Components as Basis for Biologically Active Synthetic Peptides

V. Tsetlin, I. Kasheverov, 2016 .

Labeling of Torpedo californica nicotinic acetylcholine receptor subunits by cobratoxin derivatives with photoactivatable groups of different chemical nature at Lys23.

A. Arseniev, F. Hucho, Y. Utkin, 1998, European journal of biochemistry.

α9α10 nicotinic acetylcholine receptors regulate murine bone marrow granulocyte functions.

I. Tikhonova, V. Tsetlin, V. Safronova, 2020, Immunobiology.

Snake Toxins Labeled by Green Fluorescent Protein or Its Synthetic Chromophore are New Probes for Nicotinic acetylcholine Receptors

M. Baranov, Y. Utkin, V. Tsetlin, 2021, Frontiers in Molecular Biosciences.

Scorpion toxins interact with nicotinic acetylcholine receptors

M. Serebryakova, Y. Utkin, V. Tsetlin, 2019, FEBS letters.

Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors

D. Craik, P. Corringer, David John Adams, 2017, Scientific Reports.

Water-soluble LYNX1 Residues Important for Interaction with Muscle-type and/or Neuronal Nicotinic Receptors*

P. Bregestovski, D. Dolgikh, M. Kirpichnikov, 2013, The Journal of Biological Chemistry.

Naturally occurring and synthetic peptides acting on nicotinic acetylcholine receptors.

Y. Utkin, V. Tsetlin, I. Kasheverov, 2009, Current pharmaceutical design.

Novel long-chain neurotoxins from Bungarus candidus distinguish the two binding sites in muscle-type nicotinic acetylcholine receptors.

T. Bergman, U. Kuch, D. Warrell, 2019, The Biochemical journal.

Makaluvamine G from the Marine Sponge Zyzzia fuliginosa Inhibits Muscle nAChR by Binding at the Orthosteric and Allosteric Sites

V. Tsetlin, N. Utkina, I. Shelukhina, 2018, Marine drugs.

Conjugates of α-Cobratoxin with CdSe Quantum Dots: Preparation and Biological Activity

A. Mukherjee, D. Kuznetsov, Y. Utkin, 2017 .

Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1) Is a Selective Allosteric Antagonist of α7 Nicotinic Acetylcholine Receptor

D. Dolgikh, M. Kirpichnikov, E. Lyukmanova, 2016, PloS one.

Antiviral Effects of Animal Toxins: Is There a Way to Drugs?

V. Tsetlin, I. Kasheverov, Y. Utkin, 2022, International journal of molecular sciences.

Pancreatic and snake venom presynaptically active phospholipases A2 inhibit nicotinic acetylcholine receptors

G. Faure, T. Andreeva, Y. Utkin, 2017, PloS one.

Possible involvement of neuronal nicotinic acetylcholine receptors in compensatory brain mechanisms at early stages of Parkinson’s disease

P. Slominsky, Y. Utkin, V. Tsetlin, 2017, Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry.

Novel Three-Finger Neurotoxins from Naja melanoleuca Cobra Venom Interact with GABAA and Nicotinic Acetylcholine Receptors

T. Andreeva, Y. Utkin, V. Tsetlin, 2021, Toxins.

Nicotinic Acetylcholine Receptors Are Novel Targets of APETx-like Toxins from the Sea Anemone Heteractis magnifica

J. Tytgat, S. Peigneur, P. Dmitrenok, 2022, Toxins.

Azemiopsin from Azemiops feae Viper Venom, a Novel Polypeptide Ligand of Nicotinic Acetylcholine Receptor

D. Bertrand, W. Sieghart, A. J. Thompson, 2012, The Journal of Biological Chemistry.

Marine compound rhizochalinin shows high in vitro and in vivo efficacy in castration resistant prostate cancer

S. Venz, C. Bokemeyer, T. Steuber, 2016, Oncotarget.

Arachidonoylcholine and Other Unsaturated Long-Chain Acylcholines Are Endogenous Modulators of the Acetylcholine Signaling System

V. Tsetlin, Y. Palikova, I. Dyachenko, 2020, Biomolecules.

Marine Natural Products Acting on the Acetylcholine-Binding Protein and Nicotinic Receptors: From Computer Modeling to Binding Studies and Electrophysiology

Christoph Methfessel, V. Stonik, V. Tsetlin, 2014, Marine drugs.

Curare alkaloids from Matis Dart Poison: Comparison with d-tubocurarine in interactions with nicotinic, 5-HT3 serotonin and GABAA receptors

S. Lummis, R. Bussmann, V. Tsetlin, 2019, PloS one.

2 | THREE-FINGER PROTEINS FROM SNAKE VENOMS: AN INTRODUC TION

Y. Utkin, V. Tsetlin, I. Kasheverov, 2021 .

Three‐finger proteins from snakes and humans acting on nicotinic receptors: Old and new

Y. Utkin, V. Tsetlin, I. Kasheverov, 2020, Journal of neurochemistry.

A model for short alpha-neurotoxin bound to nicotinic acetylcholine receptor from Torpedo californica: Comparison with long-chain alpha-neurotoxins and alpha-conotoxins

Konstantin V. Shaitan, D. Yu. Mordvintsev, Ya. L. Polyak, 2005, Comput. Biol. Chem..

The solid-state catalytic isotope exchange of hydrogen in α-conotoxin G1 by the tritium spillover

Yu. A. Borisov, A. Arseniev, E. Bocharov, 2000, Russian Journal of Bioorganic Chemistry.

Chapter 4 Peptide and Protein Neurotoxin Toolbox in Research on Nicotinic Acetylcholine Receptors

V. Tsetlin, I. Kasheverov, 2017 .

Peptide and Protein Neurotoxin Toolbox in Research on Nicotinic Acetylcholine Receptors

V. Tsetlin, I. Kasheverov, 2014 .

Polypeptide and peptide toxins, magnifying lenses for binding sites in nicotinic acetylcholine receptors.

Y. Utkin, V. Tsetlin, I. Kasheverov, 2009, Biochemical pharmacology.

α‐Conotoxin analogs with additional positive charge show increased selectivity towards Torpedo californica and some neuronal subtypes of nicotinic acetylcholine receptors

A. Smit, Y. Utkin, V. Tsetlin, 2006 .

α‐Conotoxin GI benzoylphenylalanine derivatives

V. S. Pashkov, D. C. Chiara, Jonathan B. Cohen, 2006 .

Natural α-conotoxins and their synthetic analogues in study of nicotinic acetylcholine receptors

Y. Utkin, V. Tsetlin, I. Kasheverov, 2006, Russian Journal of Bioorganic Chemistry.

A Comparative Study on Selectivity of α-Conotoxins GI and ImI Using Their Synthetic Analogues and Derivatives

Y. Utkin, V. Tsetlin, I. Kasheverov, 2003, Neurochemical Research.

Photoactivatable Analogues of α-Conotoxins GI and MI and Their Interaction with Nicotinic Acetylcholine Receptor

A. Rozhkova, Y. Utkin, V. Tsetlin, 2002, Russian Journal of Bioorganic Chemistry.

Photoactivatable alpha-conotoxins reveal contacts with all subunits as well as antagonist-induced rearrangements in the Torpedo californica acetylcholine receptor.

A. Rozhkova, V. Ivanov, Y. Utkin, 2001, European journal of biochemistry.

Analysis of specificity of antibodies against synthetic fragments of different neuronal nicotinic acetylcholine receptor subunits

V. Tsetlin, I. Shelukhina, I. Kasheverov, 2006, Biochemistry (Moscow).

Natural Compounds Interacting with Nicotinic Acetylcholine Receptors: From Low-Molecular Weight Ones to Peptides and Proteins

V. Stonik, Y. Utkin, V. Tsetlin, 2015, Toxins.

Isomerization of Asp7 in Beta-Amyloid Enhances Inhibition of the α7 Nicotinic Receptor and Promotes Neurotoxicity

A. Makarov, M. Hollmann, V. Mitkevich, 2019, Cells.

The effect of MII α-conotoxin and its N-terminal derivatives on Ca2+- and Na+-signals induced by nicotine in SH-SY5Y neuroblastoma cells

L. Khiroug, A. Surin, O. Salminen, 2012, Russian Journal of Bioorganic Chemistry.

6-Bromohypaphorine from Marine Nudibranch Mollusk Hermissenda crassicornis is an Agonist of Human α7 Nicotinic Acetylcholine Receptor

V. Stonik, V. Tsetlin, T. Makarieva, 2015, Marine drugs.

High Selectivity of an α-Conotoxin LvIA Analogue for α3β2 Nicotinic Acetylcholine Receptors Is Mediated by β2 Functionally Important Residues.

Xinquan Wang, V. Tsetlin, Jinfang Yu, 2020, Journal of medicinal chemistry.

α‐Bungarotoxin interacts with the rat brain tachykinin receptors

Y. Utkin, V. Tsetlin, I. Kasheverov, 1989, FEBS letters.

Assembly of nicotinic and other Cys‐loop receptors

V. Tsetlin, I. Kasheverov, D. Kuzmin, 2011, Journal of neurochemistry.

Spatial Structure and Activity of Synthetic Fragments of Lynx1 and of Nicotinic Receptor Loop C Models

K. Mineev, A. Arseniev, Y. Utkin, 2020, Biomolecules.

From Synthetic Fragments of Endogenous Three-Finger Proteins to Potential Drugs

Y. Utkin, V. Tsetlin, I. Kasheverov, 2019, Front. Pharmacol..

Crystal Structure of the Monomeric Extracellular Domain of α9 Nicotinic Receptor Subunit in Complex With α-Conotoxin RgIA: Molecular Dynamics Insights Into RgIA Binding to α9α10 Nicotinic Receptors

V. Tsetlin, S. Tzartos, A. Papakyriakou, 2019, Front. Pharmacol..

Oligoarginine Peptides, a New Family of nAChR Inhibitors.

R. Katsarava, N. Zavradashvili, V. Tsetlin, 2019, Molecular Pharmacology.

Design of New α-Conotoxins: From Computer Modeling to Synthesis of Potent Cholinergic Compounds

V. Tsetlin, I. Kasheverov, M. Zhmak, 2011, Marine drugs.

NMR Structure and Action on Nicotinic Acetylcholine Receptors of Water-soluble Domain of Human LYNX1*

D. Bertrand, K. Mineev, A. Arseniev, 2011, The Journal of Biological Chemistry.

Neurotoxins from Snake Venoms and α-Conotoxin ImI Inhibit Functionally Active Ionotropic γ-Aminobutyric Acid (GABA) Receptors*

W. Sieghart, D. Dolgikh, E. Lyukmanova, 2015, The Journal of Biological Chemistry.

Point Mutations of Nicotinic Receptor α1 Subunit Reveal New Molecular Features of G153S Slow-Channel Myasthenia

V. Tsetlin, I. Kasheverov, D. Kudryavtsev, 2021, Molecules.

Reverse-phase chromatography isolation and MALDI mass spectrometry of the acetylcholine receptor subunits.

F. Hucho, Y. Utkin, V. Tsetlin, 1998, Protein expression and purification.

α7- and α9-Containing Nicotinic Acetylcholine Receptors in the Functioning of Immune System and in Pain

V. Tsetlin, I. Shelukhina, I. Kasheverov, 2023, International journal of molecular sciences.

Refolding of the Escherichia coli expressed extracellular domain of alpha 7 nicotinic acetylcholine receptor.

V. Tsetlin, E. Shibanova, I. Kasheverov, 2002, European journal of biochemistry.

Substance P derivatives with photoactivatable labels in the N-terminal part of the molecule.

Y. Utkin, V. Tsetlin, P. Franke, 2009, The journal of peptide research : official journal of the American Peptide Society.

Complex approach for analysis of snake venom α-neurotoxins binding to HAP, the high-affinity peptide

E. Shirshin, R. Efremov, V. Tsetlin, 2020, Scientific Reports.

Analysis of binding centers in nicotinic receptors with the aid of synthetic peptides

M. Alfimov, V. Tsetlin, I. Shelukhina, 2016, Doklady Biochemistry and Biophysics.

Effect of a peptide modeling the nicotinic receptor binding site on the spectral and luminescent properties of dye complexes with cucurbit[8]uril

M. Alfimov, Y. Utkin, V. Tsetlin, 2016, High Energy Chemistry.

Dimeric α-Cobratoxin X-ray Structure

D. Bertrand, T. Sixma, T. Andreeva, 2012, The Journal of Biological Chemistry.

Dimeric -Cobratoxin X-ray Structure LOCALIZATIONOFINTERMOLECULARDISULFIDESANDPOSSIBLEMODEOFBINDINGTO NICOTINICACETYLCHOLINERECEPTORS *

D. Bertrand, T. Sixma, T. Andreeva, 2012 .

Rational design of new ligands for nicotinic receptors on the basis of α-conotoxin PnIA

R. Efremov, V. Tsetlin, A. Chugunov, 2015, Doklady Biochemistry and Biophysics.

Muscle-type , neuronal and “ non-neuronal ” nAChRs — Brief overview

V. Tsetlin, I. Kasheverov, 2018 .

Scope and limitations of pseudoprolines as individual amino acids in peptide synthesis

I. Kasheverov, I. Ivanov, Nikita D. Timofeev, 2021, Amino Acids.

Inhibition of Nicotinic Acetylcholine Receptors, a Novel Facet in the Pleiotropic Activities of Snake Venom Phospholipases A2

T. Andreeva, Y. Utkin, V. Tsetlin, 2014, PloS one.

An unusual phospholipase A₂ from puff adder Bitis arietans venom--a novel blocker of nicotinic acetylcholine receptors.

T. Andreeva, Y. Utkin, V. Tsetlin, 2011, Toxicon : official journal of the International Society on Toxinology.

Phospholipases A2 isolated from snake venoms block acetylcholine-elicited currents in identified Lymnaea stagnalis neurons

T. Andreeva, Y. Utkin, V. Tsetlin, 2013, Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology.

The new peptide from the Fea’s viper Azemiops feae venom interacts with nicotinic acetylcholine receptors

Hoang Ngoc Anh, Y. Utkin, V. Tsetlin, 2012, Doklady Biochemistry and Biophysics.

Development of a recombinant immunotoxin for the immunotherapy of autoreactive lymphocytes expressing MOG-specific BCRs

A. Tonevitsky, D. Sakharov, A. Belyy, 2016, Biotechnology Letters.

Ultrafast, Ultrasensitive Detection and Imaging of Single Cardiac Troponin-T Molecules.

R. Esenaliev, P. Melentiev, V. Tsetlin, 2020, ACS sensors.

Bacterial production and refolding from inclusion bodies of a “Weak” toxin, a disulfide rich protein

A. Arseniev, D. Dolgikh, M. Kirpichnikov, 2009, Biochemistry (Moscow).

Central loop of non-conventional toxin WTX from Naja kaouthia is important for interaction with nicotinic acetylcholine receptors.

A. Arseniev, D. Dolgikh, M. Kirpichnikov, 2016, Toxicon : official journal of the International Society on Toxinology.

Human neuromodulator SLURP-1: Bacterial expression, binding to muscle-type nicotinic acetylcholine receptor, secondary structure, and conformational heterogeneity in solution

A. Arseniev, D. Dolgikh, M. Kirpichnikov, 2013, Biochemistry (Moscow).

Diversity of nicotinic receptors mediating Cl− current in Lymnaea neurons distinguished with specific agonists and antagonist

Y. Utkin, V. Tsetlin, I. Kasheverov, 2005, Neuroscience Letters.

Peptides from the Sea Anemone Metridium senile with Modified Inhibitor Cystine Knot (ICK) Fold Inhibit Nicotinic Acetylcholine Receptors

K. Mineev, Y. Andreev, Klara Stensvåg, 2022, Toxins.

Analogs of 6-Bromohypaphorine with Increased Agonist Potency for α7 Nicotinic Receptor as Anti-Inflammatory Analgesic Agents

V. Tsetlin, V. A. Palikov, Y. Palikova, 2023, Marine drugs.

Phospholipases A2 isolated from snake venoms block acetylcholine-elicited currents in identified Lymnaea stagnalis neurons

T. Andreeva, Y. Utkin, V. Tsetlin, 2013, Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology.

From crystal structure of α-conotoxin GIC in complex with Ac-AChBP to molecular determinants of its high selectivity for α3β2 nAChR

S. Xiang, Xi Liu, Xinquan Wang, 2016, Scientific Reports.

Patient-derived glioblastoma neurosphere cultures differentially express nicotinic acetylcholine receptors depending on ambient choline

V. Tsetlin, I. Kasheverov, D. Kudryavtsev, 2023, bioRxiv.

Fifty Years of Animal Toxin Research at the Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry RAS

I. Shelukhina, I. Kasheverov, Victor Tsetlin, 2023, International journal of molecular sciences.

Comparison of Conformations and Interactions with Nicotinic Acetylcholine Receptors for E. coli-Produced and Synthetic Three-Finger Protein SLURP-1

I. Shelukhina, I. Kasheverov, D. Kudryavtsev, 2023, International Journal of Molecular Sciences.