J. Elferich

发表

Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context

E. Gouaux, Hui Wang, J. Elferich, 2012, Nature Structural &Molecular Biology.

Using computational and experimental approaches to understand protein function : application to proprotein convertases and other disease-related proteins

J. Elferich, 2015 .

Putting the Pieces Together: the Hair Cell Transduction Complex

J. R. Holt, E. Gouaux, A. Ballesteros, 2021, Journal of the Association for Research in Otolaryngology.

The Mechanism by Which a Propeptide-encoded pH Sensor Regulates Spatiotemporal Activation of Furin*

U. Shinde, J. Elferich, G. Thomas, 2013, The Journal of Biological Chemistry.

Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5

E. Gouaux, A. Goehring, Huaying Zhao, 2018, eLife.

Mechanism of Fine-tuning pH Sensors in Proprotein Convertases

U. Shinde, J. Elferich, Danielle M. Williamson, 2015, The Journal of Biological Chemistry.

PROPEPTIDES OF PROTEASES EVOLVED SENSORS TO EXPLOIT ORGANELLAR PH

Bala Krishnamoorthy, U. Shinde, J. Elferich, 2012 .

Mutant calreticulin‐expressing cells induce monocyte hyperreactivity through a paracrine mechanism

B. Druker, A. Agarwal, E. Traer, 2016, American journal of hematology.

Molecular structures and conformations of protocadherin-15 and its complexes on stereocilia elucidated by cryo-electron tomography

E. Gouaux, A. Goehring, J. Elferich, 2021, eLife.

Molecular structure and conformation of stereocilia tip-links elucidated by cryo-electron tomography

E. Gouaux, A. Goehring, J. Elferich, 2021, bioRxiv.

Molecular structures and conformations of protocadherin-15 and its complexes on stereocilia 3 elucidated by cryo-electron tomography 4

A. Goehring, J. Elferich, Sarah Clark, 2022 .

Foretinib is a potent inhibitor of oncogenic ROS1 fusion proteins

S. Lowe, B. Druker, A. Agarwal, 2013, Proceedings of the National Academy of Sciences.

An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I

Jimmy D. Dikeakos, J. Dikeakos, G. Thomas, 2012, Molecular biology of the cell.

Monoubiquitination Is Critical for Ovarian Tumor Domain-containing Ubiquitin Aldehyde Binding Protein 1 (Otub1) to Suppress UbcH5 Enzyme and Stabilize p53 Protein*

Yuhuang Li, M. Dai, L. David, 2014, Journal of Biological Chemistry.

MonoubiquitinationIsCriticalforOvarianTumor Domain-containingUbiquitinAldehydeBindingProtein1 (Otub1)toSuppressUbcH5EnzymeandStabilizep53Protein *

Yuhuang Li, M. Dai, L. David, 2014 .

Inhibition of interleukin-1 receptor-associated kinase-1 is a therapeutic strategy for acute myeloid leukemia subtypes

Samuel H. Payne, B. Druker, M. Mori, 2018, Leukemia.

Proteomic analysis and molecular modelling characterize the iron-regulatory protein haemojuvelin/repulsive guidance molecule c.

P. Rotwein, L. David, M. Nili, 2013, The Biochemical journal.

Molecular mechanism of prestin electromotive signal amplification

E. Gouaux, E. Tajkhorshid, H. V. Gersdorff, 2021, Cell.

Defocus Corrected Large Area Cryo-EM (DeCo-LACE) for label-free detection of molecules across entire cell sections

N. Grigorieff, Giulia Schiroli, J. Elferich, 2022, bioRxiv.

Determination of Histidine pKa Values in the Propeptides of Furin and Proprotein Convertase 1/3 Using Histidine Hydrogen-Deuterium Exchange Mass Spectrometry.

L. David, U. Shinde, J. Elferich, 2015, Analytical chemistry.

Cotranslational Folding Inhibits Translocation from Within the Ribosome–Sec61 Translocon Complex

W. Skach, Brian J. Conti, U. Shinde, 2014, Nature Structural &Molecular Biology.

Pacritinib, a Dual FLT3/JAK2 Inhibitor, Reduces Irak-1 Signaling in Acute Myeloid Leukemia

B. Druker, J. Singer, A. Agarwal, 2015 .

Substrate Inhibition of Uracil Phosphoribosyltransferase by Uracil Can Account for the Uracil Growth Sensitivity of Leishmania donovani Pyrimidine Auxotrophs*

P. Yates, Radika Soysa, Isaac P. Forquer, 2013, The Journal of Biological Chemistry.

Propeptides are sufficient to regulate organelle-specific pH-dependent activation of furin and proprotein convertase 1/3.

G. Thomas, U. Shinde, J. Elferich, 2012, Journal of molecular biology.

Conformational selection in substrate recognition by Hsp70 chaperones.

Matthias J. Feige, J. Buchner, C. Becker, 2013, Journal of molecular biology.

KHARON1 Mediates Flagellar Targeting of a Glucose Transporter in Leishmania mexicana and Is Critical for Viability of Infectious Intracellular Amastigotes*

S. Landfear, L. David, P. Yates, 2013, The Journal of Biological Chemistry.

Identification of the Intracellular Gate for a Member of the Equilibrative Nucleoside Transporter (ENT) Family*

S. Landfear, R. Valdés, U. Shinde, 2014, The Journal of Biological Chemistry.

Propeptides of eukaryotic proteases encode histidines to exploit organelle pH for regulation

U. Shinde, J. Elferich, Danielle M. Williamson, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Spatiotemporal Activation of Furin Propeptide-encoded pH Sensor Regulates The Mechanism by Which a Protein Structure and Folding :

U. Shinde, J. Elferich, G. Thomas, 2013 .

HOTSPUR: A Real-time Interactive Preprocessing System for Cryo-EM Data.

E. Gouaux, C. Yoshioka, J. Elferich, 2019, Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada.

Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5

E. Gouaux, A. Goehring, Huaying Zhao, 2018, eLife.

Author response: Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5

E. Gouaux, A. Goehring, Huaying Zhao, 2018 .

Monoubiquitination Is Critical for Ovarian Tumor Domain-containing Ubiquitin Aldehyde Binding Protein 1 (Otub1) to Suppress UbcH5 Enzyme and Stabilize p53 Protein*

Yuhuang Li, M. Dai, L. David, 2014, The Journal of Biological Chemistry.