A. Shanmugham

发表

Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase.

T. Sixma, H. Ovaa, A. Faesen, 2011, Molecular cell.

Chapter 4 Functional reconstitution of the E . coli Tat system by subunits obtained from a thermophilic bacterium

P. Völler, Y. Bollen, H. Lill, 2010 .

Nonhydrolyzable ubiquitin-isopeptide isosteres as deubiquitinating enzyme probes.

T. Sixma, H. Ovaa, A. Faesen, 2010, Journal of the American Chemical Society.

Surface plasmon resonance biosensor assay for the analysis of small-molecule inhibitor binding to human and parasitic phosphodiesterases.

I. D. de Esch, R. Leurs, M. Siderius, 2016, Analytical biochemistry.

DUBs and disease: activity assays for inhibitor development.

H. Ovaa, A. Shanmugham, 2008, Current opinion in drug discovery & development.

Supplemental Information Mechanism of USP 7 / HAUSP Activation by Its C-Terminal Ubiquitin-like Domain and Allosteric Regulation by GMP-Synthetase

T. Sixma, H. Ovaa, A. Faesen, 2011 .

Membrane binding of twin arginine preproteins as an early step in translocation.

Y. Bollen, H. Lill, Yves J M Bollen, 2006, Biochemistry.

Fragment-Based Screening in Tandem with Phenotypic Screening Provides Novel Antiparasitic Hits

Rob Leurs, Marco Siderius, Ewald Edink, 2015, Journal of biomolecular screening.

The twin arginine system rescues the transport of folded Sec substrates

P. Völler, Y. Bollen, R. Srivastava, 2010 .

Catechol pyrazolinones as trypanocidals: fragment-based design, synthesis, and pharmacological evaluation of nanomolar inhibitors of trypanosomal phosphodiesterase B1.

Rob Leurs, Emily Adams, Paul Cos, 2012, Journal of medicinal chemistry.

Fragment-Based Screening in Tandem with Phenotypic Screening Provides Novel Antiparasitic Hits

I. D. de Esch, R. Leurs, M. Siderius, 2015, Journal of biomolecular screening.

Catechol pyrazolinones as trypanocidals: fragment-based design, synthesis, and pharmacological evaluation of nanomolar inhibitors of trypanosomal phosphodiesterase B1.

I. D. de Esch, R. Leurs, E. Chatelain, 2012, Journal of medicinal chemistry.

Surface plasmon resonance biosensor assay for the analysis of small-molecule inhibitor binding to human and parasitic phosphodiesterases.

I. D. de Esch, R. Leurs, M. Siderius, 2016, Analytical biochemistry.

The Hydrophobic Core of Twin-Arginine Signal Sequences Orchestrates Specific Binding to Tat-Pathway Related Chaperones

Adil Bakayan, P. Völler, Y. Bollen, 2012, PloS one.

Chapter 3 Interactions of Tat pathway-related chaperone proteins

Adil Bakayan, Y. Bollen, H. Lill, 2010 .