D. Sbrissa

发表

A. Shisheva, O. Ikonomov, D. Sbrissa, 2009, The Journal of Biological Chemistry.

Mammalian Cell Morphology and Endocytic Membrane Homeostasis Require Enzymatically Active Phosphoinositide 5-Kinase PIKfyve*

A. Shisheva, O. Ikonomov, D. Sbrissa, 2001, The Journal of Biological Chemistry.

The metabolism of 4-deoxy-4-fluoro-D-glucose in Pseudomonas putida

D. Sbrissa, J. Mcintosh, N. F. Taylor, 1990 .

Apilimod, a candidate anticancer therapeutic, arrests not only PtdIns(3,5)P2 but also PtdIns5P synthesis by PIKfyve and induces bafilomycin A1-reversible aberrant endomembrane dilation

A. Shisheva, O. Ikonomov, D. Sbrissa, 2018, PloS one.

Analysis of potential binding of the recombinant Rab9 effector p40 to phosphoinositide-enriched synthetic liposomes.

A. Shisheva, O. Ikonomov, D. Sbrissa, 2005, Methods in enzymology.

Kinesin Adapter JLP Links PIKfyve to Microtubule-based Endosome-to-Trans-Golgi Network Traffic of Furin*

A. Shisheva, O. Ikonomov, D. Sbrissa, 2009, Journal of Biological Chemistry.

A novel cross-talk between CXCR4 and PI4KIIIα in prostate cancer cells.

A. Shisheva, P. Stemmer, U. Vaishampayan, 2018, Oncogene.

ArPIKfyve Regulates Sac3 Protein Abundance and Turnover

A. Shisheva, O. Ikonomov, D. Sbrissa, 2010, The Journal of Biological Chemistry.

Class III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasis.

A. Shisheva, E. Tisdale, P. Garg, 2015, Biochimica et biophysica acta.

Molecular basis for the insulinomimetic effects of C-peptide

G. Grunberger, A. Shisheva, S. T. Mathews, 2001, Diabetologia.

Role for a novel signaling intermediate, phosphatidylinositol 5-phosphate, in insulin-regulated F-actin stress fiber breakdown and GLUT4 translocation.

J. Straková, A. Shisheva, O. Ikonomov, 2004, Endocrinology.

Functional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636.

A. Shisheva, O. Ikonomov, D. Sbrissa, 2012, American journal of physiology. Cell physiology.

ArPIKfyve-PIKfyve interaction and role in insulin-regulated GLUT4 translocation and glucose transport in 3T3-L1 adipocytes.

A. Shisheva, O. Ikonomov, D. Sbrissa, 2007, Experimental cell research.

The PIKfyve-ArPIKfyve-Sac3 triad in human breast cancer: Functional link between elevated Sac3 phosphatase and enhanced proliferation of triple negative cell lines.

A. Shisheva, Xuequn Chen, O. Ikonomov, 2013, Biochemical and biophysical research communications.

Localized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusion.

A. Shisheva, O. Ikonomov, D. Sbrissa, 2006, American journal of physiology. Cell physiology.

Protein and Vesicle Trafficking , Cytoskeleton Localized PtdIns 3 , 5P 2 synthesis to regulate early endosome dynamics and fusion

A. Shisheva, O. Ikonomov, D. Sbrissa, 2006 .

The Protein Complex of Neurodegeneration-related Phosphoinositide Phosphatase Sac3 and ArPIKfyve Binds the Lewy Body-associated Synphilin-1, Preventing Its Aggregation*

Rita Kumar, A. Shisheva, Xuequn Chen, 2015, The Journal of Biological Chemistry.

Requirement for PIKfyve enzymatic activity in acute and long-term insulin cellular effects.

A. Shisheva, O. Ikonomov, D. Sbrissa, 2002, Endocrinology.

Selective insulin-induced activation of class IA phosphoinositide 3-kinase in PIKfyve immune complexes from 3T3-L1 adipocytes

A. Shisheva, O. Ikonomov, D. Sbrissa, 2001, Molecular and Cellular Endocrinology.

PIKfyve, a Mammalian Ortholog of Yeast Fab1p Lipid Kinase, Synthesizes 5-Phosphoinositides

A. Shisheva, O. Ikonomov, D. Sbrissa, 1999, The Journal of Biological Chemistry.

Localization and Insulin-regulated Relocation of Phosphoinositide 5-Kinase PIKfyve in 3T3-L1 Adipocytes*

A. Shisheva, O. Ikonomov, D. Sbrissa, 2001, The Journal of Biological Chemistry.

Functional Dissection of Lipid and Protein Kinase Signals of PIKfyve Reveals the Role of PtdIns 3,5-P2 Production for Endomembrane Integrity*

M. Kanzaki, J. Pessin, A. Shisheva, 2002, The Journal of Biological Chemistry.

PIKfyve inhibitor cytotoxicity requires AKT suppression and excessive cytoplasmic vacuolation

A. Shisheva, G. Altankov, O. Ikonomov, 2018, Toxicology and applied pharmacology.

Plentiful PtdIns5P from scanty PtdIns(3,5)P2 or from ample PtdIns? PIKfyve‐dependent models: Evidence and speculation (response to: DOI 10.1002/bies.201300012)

A. Shisheva, O. Ikonomov, D. Sbrissa, 2015, BioEssays : news and reviews in molecular, cellular and developmental biology.

Phosphatidylinositol 5-Phosphate Biosynthesis Is Linked to PIKfyve and Is Involved in Osmotic Response Pathway in Mammalian Cells*

A. Shisheva, O. Ikonomov, D. Sbrissa, 2002, The Journal of Biological Chemistry.

Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency.

A. Shisheva, L. M. Compton, P. Garg, 2016, American journal of physiology. Cell physiology.

PIKfyve Kinase and SKD1 AAA ATPase Define Distinct Endocytic Compartments

T. Cover, A. Shisheva, T. Yoshimori, 2002, The Journal of Biological Chemistry.

Severe Consequences of SAC3/FIG4 Phosphatase Deficiency to Phosphoinositides in Patients with Charcot-Marie-Tooth Disease Type-4J

A. Shisheva, Jun Li, D. Sbrissa, 2019, Molecular Neurobiology.

A Mammalian Ortholog of Saccharomyces cerevisiae Vac14 That Associates with and Up-Regulates PIKfyve Phosphoinositide 5-Kinase Activity

J. Straková, A. Shisheva, R. Silver, 2004, Molecular and Cellular Biology.

Acquisition of Unprecedented Phosphatidylinositol 3,5-Bisphosphate Rise in Hyperosmotically Stressed 3T3-L1 Adipocytes, Mediated by ArPIKfyve-PIKfyve Pathway*

A. Shisheva, D. Sbrissa, 2005, Journal of Biological Chemistry.

Chemical synthesis and molecular recognition of phosphatase-resistant analogues of phosphatidylinositol-3-phosphate.

G. Prestwich, A. Shisheva, T. Kutateladze, 2006, Journal of the American Chemical Society.

Phosphatidylinositol 3-Phosphate-interacting Domains in PIKfyve

A. Shisheva, O. Ikonomov, D. Sbrissa, 2002, The Journal of Biological Chemistry.

The Phosphoinositide Kinase PIKfyve Is Vital in Early Embryonic Development

D. Rappolee, A. Shisheva, Jian-Ping Jin, 2011, The Journal of Biological Chemistry.

Cloning, Characterization, and Expression of a Novel Zn2+-Binding FYVE Finger-Containing Phosphoinositide Kinase in Insulin-Sensitive Cells

A. Shisheva, O. Ikonomov, D. Sbrissa, 1999, Molecular and Cellular Biology.

Unexpected severe consequences of Pikfyve deletion by aP2‐ or Aq‐promoter‐driven Cre expression for glucose homeostasis and mammary gland development

A. Shisheva, O. Ikonomov, D. Sbrissa, 2016, Physiological reports.

YM201636, an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, halts glucose entry by insulin in adipocytes.

A. Shisheva, O. Ikonomov, D. Sbrissa, 2009, Biochemical and biophysical research communications.

Core Protein Machinery for Mammalian Phosphatidylinositol 3,5-Bisphosphate Synthesis and Turnover That Regulates the Progression of Endosomal Transport

T. Takenawa, T. Ijuin, A. Shisheva, 2007, Journal of Biological Chemistry.

Sac3 Is an Insulin-regulated Phosphatidylinositol 3,5-Bisphosphate Phosphatase

T. Takenawa, T. Ijuin, A. Shisheva, 2009, The Journal of Biological Chemistry.

ArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionality.

A. Shisheva, O. Ikonomov, D. Sbrissa, 2008, Journal of molecular biology.

cdc-Like/Dual-Specificity Tyrosine Phosphorylation–Regulated Kinases Inhibitor Leucettine L41 Induces mTOR-Dependent Autophagy: Implication for Alzheimer’s Disease

L. Meijer, B. Payrastre, A. Shisheva, 2014, Molecular Pharmacology.

Active PIKfyve Associates with and Promotes the Membrane Attachment of the Late Endosome-to-trans-Golgi Network Transport Factor Rab9 Effector p40*

R. Finley, A. Shisheva, O. Ikonomov, 2003, Journal of Biological Chemistry.

PIKfyve controls fluid phase endocytosis but not recycling/degradation of endocytosed receptors or sorting of procathepsin D by regulating multivesicular body morphogenesis.

Michelangelo Foti, M. Foti, A. Shisheva, 2003, Molecular biology of the cell.

Adaptor proteins mediate CXCR4 and PI4KA crosstalk in prostate cancer cells and the significance of PI4KA in bone tumor growth

U. Vaishampayan, M. Cher, D. Sbrissa, 2023, Research square.

Muscle-specific Pikfyve gene disruption causes glucose intolerance, insulin resistance, adiposity, and hyperinsulinemia but not muscle fiber-type switching.

A. Shisheva, G. Cartee, Jian-Ping Jin, 2013, American journal of physiology. Endocrinology and metabolism.

Origin of molecular species of diacylglycerol induced by bombesin in smooth muscle cells from rabbit rectosigmoid.

K. Bitar, D. Sbrissa, A. Hajra, 1998, The American journal of physiology.

Small molecule PIKfyve inhibitors as cancer therapeutics: Translational promises and limitations.

A. Shisheva, O. Ikonomov, D. Sbrissa, 2019, Toxicology and applied pharmacology.

PIKfyve lipid kinase is a protein kinase: downregulation of 5'-phosphoinositide product formation by autophosphorylation.

A. Shisheva, O. Ikonomov, D. Sbrissa, 2000, Biochemistry.

Phosphatidylinositol 3-Phosphate-interacting Domains in PIKfyve BINDING SPECIFICITY AND ROLE IN PIKfyve ENDOMEMBRANE LOCALIZATION*

A. Shisheva, O. Ikonomov, D. Sbrissa, 2002 .

ArPIKfyve REGULATES Sac3 PROTEIN ABUNDANCE AND TURNOVER: DISRUPTION OF THE MECHANISM BY Sac3 I41T MUTATION CAUSING CHARCOT-MARIE-TOOTH 4J DISORDER

A. Shisheva, O. Ikonomov, D. Sbrissa, 2010 .

Sac3 Is an Insulin-regulated Phosphatidylinositol 3,5-Bisphosphate Phosphatase

T. Takenawa, T. Ijuin, A. Shisheva, 2009, The Journal of Biological Chemistry.

A Novel Interaction between Chemokine and Phosphoinositide Signaling in Metastatic Prostate Cancer

M. Cher, D. Sbrissa, S. Chinni, 2023, Medical research archives.

ArPIKfyve REGULATES Sac 3 PROTEIN ABUNDANCE AND TURNOVER : DISRUPTION OF THE MECHANISM BY Sac 3 I 41 T MUTATION CAUSING CHARCOT-MARIE-TOOTH 4 J DISORDER

A. Shisheva, O. Ikonomov, D. Sbrissa, 2010 .