F. Melani

发表

Design and solid phase synthesis of new DOTA conjugated (+)-biotin dimers planned to develop molecular weight-tuned avidin oligomers.

M. Bartoli, M. Ginanneschi, A. Papini, 2015, Organic & biomolecular chemistry.

Interaction between naproxen and chemically modified β-cyclodextrins in the liquid and solid state

P. Mura, F. Melani, G. Bettinetti, 1995 .

New 3-, 8-disubstituted pyrazolo[5,1-c][1,2,4]benzotriazines useful for studying the interaction with the HBp-3 area (hydrogen bond point area) in the benzodiazepine site on the γ-aminobutyric acid type A (GABAA) receptor.

C. Martini, S. Daniele, S. Selleri, 2011, Bioorganic & medicinal chemistry.

Novel 3-aroylpyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: synthesis, pharmacological and molecular modeling studies.

C. Martini, C. Ghelardini, M. Montali, 2008, Bioorganic & medicinal chemistry.

New docking CFF91 parameters specific for cyclodextrin inclusion complexes

C. Bonaccini, P. Gratteri, P. Mura, 2003 .

Authentication of the geographical origin of virgin olive oils from the main worldwide producing countries: A new combination of HS-SPME-GC-MS analysis of volatile compounds and chemometrics applied to 1217 samples

L. Cecchi, E. Giambanelli, N. Mulinacci, 2020, Food Control.

4-Heteroaryl Substituted Amino-3,5-Dicyanopyridines as New Adenosine Receptor Ligands: Novel Insights on Structure-Activity Relationships and Perspectives

K. Varani, F. Vincenzi, D. Dal Ben, 2022, Pharmaceuticals.

Substituted piperazines as nootropic agents: 2- or 3-phenyl derivatives structurally related to the cognition-enhancer DM235.

C. Ghelardini, G. Bartolucci, S. Dei, 2015, Bioorganic & medicinal chemistry letters.

Tricyclic heteroaromatic systems: [1]benzopyrano-pyrazol-4-ones as benzodiazepine receptor ligands.

C. Martini, A. Lucacchini, S. Gelli, 1991, Journal of pharmaceutical sciences.

Synthesis, SAR and in vitro evaluation of new cyclic Arg-Gly-Asp pseudopentapeptides containing a s-cis peptide bond as integrin alphavbeta3 and alphavbeta5 ligands.

A. Brandi, P. Gratteri, F. M. Cordero, 2008, Bioorganic & medicinal chemistry.

New fluoro derivatives of the pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide system: evaluation of fluorine binding properties in the benzodiazepine site on γ-aminobutyrric acid type A (GABA(A)) receptor. Design, synthesis, biological, and molecular modeling investigation.

C. Martini, C. Ghelardini, S. Daniele, 2010, Journal of medicinal chemistry.

New Panx-1 Blockers: Synthesis, Biological Evaluation and Molecular Dynamic Studies

C. Ghelardini, E. Lucarini, L. di Cesare Mannelli, 2022, International journal of molecular sciences.

New 3,6‐Disubstituted Pyrazolo[1,5‐ a ]quinazolines as Ligands to GABA A Receptor Subtype

C. Martini, C. Vergelli, M. Giovannoni, 2019, Journal of Heterocyclic Chemistry.

Synthesis and A1 and A2A adenosine binding activity of some pyrano[2,3-c]pyrazol-4-ones.

C. Martini, A. Lucacchini, F. Melani, 1998, Farmaco.

HS-SPME-GC-MS Quantification of Volatile Profile of more than 1200 Virgin Olive Oils for Supporting Panel Test in their Classification: Comparison of Different Chemometric Approaches.

L. Cecchi, E. Giambanelli, N. Mulinacci, 2019, Journal of agricultural and food chemistry.

GABAA Receptor Modulators with a Pyrazolo[1,5-a]quinazoline Core: Synthesis, Molecular Modelling Studies and Electrophysiological Assays

M. P. Mascia, C. Vergelli, M. Giovannoni, 2022, International journal of molecular sciences.

Evaluation of the separation mechanism of electrokinetic chromatography with a microemulsion and cyclodextrins using NMR and molecular modeling

S. Furlanetto, S. Pinzauti, S. Orlandini, 2011, Electrophoresis.

Tricyclic heteroaromatic systems. 5H-1,2,3-triazolo[5,1-c][1,4]benzodiazepine

F. Melani, L. Cecchi, V. Colotta, 2009 .

New isobaric lignans from Refined Olive Oils as quality markers for Virgin Olive Oils.

L. Cecchi, M. Innocenti, N. Mulinacci, 2017, Food chemistry.

Is the volatile compounds profile a suitable tool for authentication of virgin olive oils (Olea europaea L.) according to cultivars? A study by using HS-SPME-GC-MS and chemometrics

L. Cecchi, B. Zanoni, E. Giambanelli, 2022, Food Control.

GRIND-derived pharmacophore model for a series of α-tropanyl derivative ligands of the sigma-2 receptor*

Maria Novella Romanelli, Gabriele Cruciani, Paola Gratteri, 2004, J. Comput. Aided Mol. Des..

Structure-activity relationships of 1,2,4-triazolo[1,5-a] quinoxalines and their 1-deaza analogues imidazo[1,2-a]quinoxalines at the benzodiazepine receptor.

C. Martini, A. Lucacchini, L. Giusti, 1994, Journal of Medicinal Chemistry.

1,3-Diarylpyrazolo[4,5-c]- and -[5,4-c]quinolin-4-ones. 4. Synthesis and specific inhibition of benzodiazepine receptor binding.

C. Martini, A. Lucacchini, F. Melani, 1987, Journal of medicinal chemistry.

Pyrazolo[4,5-c]quinolines. 2. Synthesis and specific inhibition of benzodiazepine receptor binding.

C. Martini, A. Lucacchini, F. Melani, 1986, Journal of medicinal chemistry.

Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as peripheral benzodiazepine receptor ligands: synthesis, biological evaluation and 3D-QSAR investigation.

C. Martini, B. Costa, P. Gratteri, 2005, Bioorganic & medicinal chemistry.

Tricyclic heteroaromatic systems: synthesis, [3H]flunitrazepam brain membrane binding inhibition, and structure-activity relationships of 2,3-dihydro-2-aryl-4-R-[1]benzopyrano[4,3-c]pyrazole-3-ones.

C. Martini, G. Giannaccini, A. Lucacchini, 1989, Journal of pharmaceutical sciences.

The correct synthesis of 2,3-dihydro-2-aryl-4-r-[1]benzopyrano[4,3-c]pyrazole-3-ones.

F. Melani, G. Palazzino, L. Cecchi, 1987 .

Synthesis of 5H‐10,11‐dihydropyrazolo[5,1‐c]‐[1,4]benzodiazepinederivatives. II

F. Melani, L. Cecchi, G. Filacchioni, 1984 .

Synthesis of 1,5-diaryl-3-methyl-1H-pyrazolo[4,5-c]isoquinolines and studies of binding to specific peripheral benzodiazepine binding sites.

C. Martini, G. Giannaccini, A. Lucacchini, 1989, Journal of pharmaceutical sciences.

Interaction of Naproxen with Alpha-Cyclodextrin and Its Noncyclic Analog Maltohexaose

P. Mura, F. Melani, G. Bettinetti, 1999, Pharmaceutical Research.

Computer-aided molecular modeling techniques for predicting the stability of drug–cyclodextrin inclusion complexes in aqueous solutions

P. Mura, F. Melani, M. Faucci, 2002 .

Carbon-13 Nuclear Magnetic Resonance Study of Naproxen Interaction with Cyciodextrins in Solution

Fabrizio Melani, Paola Mura, Ferdinando Giordano, 1991 .

Combined Use of Cyclodextrins and Amino Acids for the Development of Cefixime Oral Solutions for Pediatric Use

E. Casalone, P. Mura, F. Maestrelli, 2021, Pharmaceutics.

Combination of capillary electrophoresis, molecular modeling and NMR to study the enantioselective complexation of sulpiride with double cyclodextrin systems.

R. Gotti, S. Furlanetto, S. Orlandini, 2015, Journal of pharmaceutical and biomedical analysis.

Phase solubility, 1H NMR and molecular modelling studies of bupivacaine hydrochloride complexation with different cyclodextrin derivates

M. Jug, P. Mura, F. Maestrelli, 2010 .

1H-NMR and molecular modelling techniques for the investigation of the inclusion complex of econazole with alpha-cyclodextrin in the presence of malic acid.

P Mura, M T Faucci, P. Mura, 2000, Journal of pharmaceutical and biomedical analysis.

Interactions between naproxen and maltoheptaose, the non-cyclic analog ofβ-cyclodextrin

F. Giordano, P. Mura, F. Melani, 1996 .

1H-NMR NOE and molecular modelling to characterize thymol and carvacrol β-cyclodextrin complexes

A. Romani, N. Mulinacci, F. Vincieri, 1996 .

Combined approach using capillary electrophoresis, NMR and molecular modeling for ambrisentan related substances analysis: Investigation of intermolecular affinities, complexation and separation mechanism

S. Furlanetto, S. Pinzauti, S. Orlandini, 2017, Journal of pharmaceutical and biomedical analysis.

Interaction of naproxen with α-, β-, and γ-hydroxypropyl cyclodextrins in solution and in the solid state

P. Mura, F. Melani, G. Bettinetti, 1995 .

Molecular modelling and NMR NOE experiments: Complementary tools for the investigation of complex ibuproxam-β-cyclodextrin topology

N. Mulinacci, F. Vincieri, F. Melani, 1993 .

Modeling and Biological Investigations of an Unusual Behavior of Novel Synthesized Acridine‐Based Polyamine Ligands in the Binding of Double Helix and G‐Quadruplex DNA

C. Giorgi, B. Valtancoli, C. Sissi, 2010, ChemMedChem.

Stereoselective Synthesis of 1,3-Disaccharides through Diels-Alder Reactions: Part 2[ ]: Convenient Protecting Groups for Heterodienes and Conformational Evaluations

C. Nativi, Gabriele Gabrielli, B. Richichi, 2009 .

An insight on the alkaloid content of Capparis spinosa L. root by HPLC-DAD-MS, MS/MS and (1)H qNMR.

G. Pieraccini, M. Innocenti, N. Mulinacci, 2016, Journal of pharmaceutical and biomedical analysis.

13C NMR spectra of 1,3-oxathiolane, 1,3-oxathiolane 3-oxide and 1,3-oxathiolane 3,3-dioxide derivatives

E. Teodori, F. Gualtieri, F. Melani, 1986 .

Does Fermentation Really Increase the Phenolic Content in Cereals? A Study on Millet

P. Paoli, M. Bellumori, M. Innocenti, 2020, Foods.

Enhancement of viniferin production in Vitis vinifera L. cv. Alphonse Lavallée Cell suspensions by low-energy ultrasound alone and in combination with methyl jasmonate.

G. Pasqua, A. Valletta, M. Innocenti, 2012, Journal of agricultural and food chemistry.

Exploring the intermolecular interactions acting in solvent‐modified MEKC by Molecular Dynamics and NMR: The effect of n‐butanol on the separation of diclofenac and its impurities

S. Furlanetto, S. Orlandini, B. Pasquini, 2018, Journal of pharmaceutical and biomedical analysis.

Pyrazolo[1,5-a]quinazoline scaffold as 5-deaza analogue of pyrazolo[5,1-c][1,2,4]benzotriazine system: synthesis of new derivatives, biological activity on GABAA receptor subtype and molecular dynamic study

C. Martini, C. Vergelli, M. Giovannoni, 2016, Journal of enzyme inhibition and medicinal chemistry.

Benzodiazepine binding activity of some tricyclic heteroaromatic systems to define the hydrogen bonding strength of the proton donors of the receptor site

C. Costagli, A. Galli, F. Melani, 1996 .

Tricyclic heteroaromatic systems. 1,2,3,4-tetrahydropyrazolo[4,3-c][l]benzazepin-1-ones as potential antitumor agents

F. Melani, G. Palazzino, L. Cecchi, 1989 .

Design, Synthesis and Pharmacological Evaluation of New Quinoline-Based Panx-1 Channel Blockers

G. Bartolucci, M. Giovannoni, P. Paoli, 2023, International journal of molecular sciences.

Tricyclic heterocyclic systems: Pyrazolo[5′,4′:4,5]‐and pyrazolo‐[3′,4′:4,5]pyrano[2,3‐b]pyridine derivatives

F. Melani, G. Palazzino, L. Cecchi, 1988 .

Tricyclic heteroaromatic systems. [1]benzopyranopyrrol-4-ones and [1]benzopyrano-1,2,3-triazol-4-ones as benzodiazepine receptor ligands. Synthesis and structure-activity relationships.

C. Martini, G. Giannaccini, A. Lucacchini, 1990, Journal of Medicinal Chemistry.

Tricyclic Heteroaromatic Systems. (1)Benzopyranopyrrol‐4‐ones and (1)Benzopyrano‐1,2,3‐triazol‐4‐ones as Benzodiazepine Receptor Ligands. Synthesis and Structure‐Activity Relationships.

C. Martini, G. Giannaccini, A. Lucacchini, 1991 .

4,5-Dihydro-5-Oxo-Pyrazolo[1,5-a]Thieno[2,3-c]Pyrimidine: A Novel Scaffold Containing Thiophene Ring. Chemical Reactivity and In Silico Studies to Predict the Profile to GABAA Receptor Subtype

C. Vergelli, M. Giovannoni, F. Melani, 2023, Molecules.

Synthetic butanolide and tetrahydrofuran lignans with platelet activating factor antagonist activity

N. Mulinacci, F. Vincieri, F. Melani, 1991 .

Synthesis, in vivo evaluation, and molecular modeling studies of new pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide derivatives. Identification of a bifunctional hydrogen bond area related to the inverse agonism.

C. Martini, C. Ghelardini, M. Montali, 2009, Journal of medicinal chemistry.

Mechanisms for the inhibition of amyloid aggregation by small ligands

M. Ramazzotti, D. Degl’Innocenti, N. Mulinacci, 2016, Bioscience reports.

New quinoline-based PDE4 inhibitors through GSK-256066 fragment-based elaboration

C. Vergelli, M. Giovannoni, A. Cilibrizzi, 2023, Journal of Molecular Structure.