T. Hiranita

发表

Dopamine Transporter Dynamics of N-Substituted Benztropine Analogs with Atypical Behavioral Effects

J. Madura, C. K. Surratt, W. Hong, 2018, The Journal of Pharmacology and Experimental Therapeutics.

Sigma Receptor Agonists: Receptor Binding and Effects on Mesolimbic Dopamine Neurotransmission Assessed by Microdialysis

G. Tanda, C. McCurdy, C. Mesangeau, 2011, Biological Psychiatry.

A Role for Sigma Receptors in Stimulant Self Administration and Addiction

Teruo Hayashi, T. Su, G. Tanda, 2011, Pharmaceuticals.

Reinforcing Effects of σ-Receptor Agonists in Rats Trained to Self-Administer Cocaine

P. Soto, G. Tanda, J. Katz, 2010, Journal of Pharmacology and Experimental Therapeutics.

The sigma-1 receptor modulates dopamine transporter conformation and cocaine binding and may thereby potentiate cocaine self-administration in rats

S. Amara, T. Su, W. Hong, 2017, The Journal of Biological Chemistry.

Identification of the Sigma-2 Receptor: Distinct from the Progesterone Receptor Membrane Component 1 (PGRMC1)

T. Hiranita, 2016, Journal of alcoholism and drug dependence.

Identification of Antagonists Selective for Sigma Receptor Subtypes that are Active In vivo.

T. Hiranita, 2016, Journal of alcoholism and drug dependence.

Role of the σRs for Development of Medications.

T. Hiranita, 2014, Journal of alcoholism and drug dependence.

Endocannabinoid System Modulates Relapse to Methamphetamine Seeking: Possible Mediation by the Arachidonic Acid Cascade

Shigenori Watanabe, Y. Shoyama, Hiroyuki Tanaka, 2004, Neuropsychopharmacology.

New perspectives in the studies on endocannabinoid and cannabis: a role for the endocannabinoid-arachidonic acid pathway in drug reward and long-lasting relapse to drug taking.

Tsuneyuki Yamamoto, K. Anggadiredja, T. Hiranita, 2004, Journal of pharmacological sciences.

Self-Administration of Cocaine Induces Dopamine-Independent Self-Administration of Sigma Agonists

P. Soto, G. Tanda, J. Katz, 2013, Neuropsychopharmacology.

Importance of Substrate-Coupled Proton Antiport by the Vesicular Monoamine Transporter in the Actions of Amphetamines in Drosophila Brain.

Z. Freyberg, T. Hiranita, 2016, Journal of alcoholism and drug dependence.

Evaluation of the rewarding effects of mitragynine and 7-hydroxymitragynine in an intracranial self-stimulation procedure in male and female rats.

Adriaan W. Bruijnzeel, C. McCurdy, F. León, 2020, Drug and alcohol dependence.

Decreases in Cocaine Self-Administration with Dual Inhibition of the Dopamine Transporter and σ Receptors

A. Newman, P. Soto, G. Tanda, 2011, Journal of Pharmacology and Experimental Therapeutics.

action illuminated through optical monitoring of synaptic vesicles in Drosophila brain.

R. Freyberg, J. Flores, D. Sulzer, 2016 .

Interactive Effects of µ-Opioid and Adrenergic-α2 Receptor Agonists in Rats: Pharmacological Investigation of the Primary Kratom Alkaloid Mitragynine and Its Metabolite 7-Hydroxymitragynine

P. Soto, J. Wilkerson, T. Hiranita, 2022, The Journal of Pharmacology and Experimental Therapeutics.

Activity of Mitragyna speciosa ("Kratom") Alkaloids at Serotonin Receptors.

C. McCurdy, Clinton E. Canal, T. Hiranita, 2021, Journal of medicinal chemistry.

Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats

Tobias Braun, J. Wilkerson, J. Fortner, 2020, The Journal of Pharmacology and Experimental Therapeutics.

σ Receptor Effects of N-Substituted Benztropine Analogs: Implications for Antagonism of Cocaine Self-Administration

W. Hong, T. Kopajtic, J. Katz, 2017, The Journal of Pharmacology and Experimental Therapeutics.

s Receptor Effects of N-Substituted Benztropine Analogs: Implications for Antagonism of Cocaine Self-Administration

W. Hong, T. Kopajtic, J. Katz, 2017 .

Blockade of Cocaine or σ Receptor Agonist Self Administration by Subtype-Selective σ Receptor Antagonists

K. Rice, A. Abdelazeem, C. McCurdy, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Blockade of Cocaine or Sigma Receptor Agonist Self-Administration by Subtype- Selective Sigma Receptor Antagonists

K. Rice, A. Abdelazeem, C. McCurdy, 2016 .

Preclinical Efficacy of N-Substituted Benztropine Analogs as Antagonists of Methamphetamine Self-Administration in Rats

P. Soto, G. Tanda, T. Kopajtic, 2014, The Journal of Pharmacology and Experimental Therapeutics.

(-)-Trans-Δ9-Tetrahydrocannabinol-Like Discriminative-Stimulus Effects of Gabapentin in Cannabis Users.

T. Hiranita, 2016, Journal of alcoholism and drug dependence.

Methamphetamine-seeking behavior is due to inhibition of nicotinic cholinergic transmission by activation of cannabinoid CB1 receptors

Tsuneyuki Yamamoto, T. Hiranita, K. Sakimura, 2008, Neuropharmacology.

Cannabimimetic effects of abused indazole-carboxamide synthetic cannabinoid receptor agonists AB-PINACA, 5F-AB-PINACA and 5F-ADB-PINACA in mice: Tolerance, dependence and withdrawal.

T. Hiranita, W. Fantegrossi, Catheryn D. Wilson, 2022, Drug and alcohol dependence.

The discriminative stimulus effects of baclofen and gamma hydroxybutyrate in C57BL/6J mice

W. Koek, J. Wilkerson, T. Hiranita, 2022, Behavioural pharmacology.

Miscibility behavior of dipalmitoylphosphatidylcholine with a single-chain partially fluorinated amphiphile in Langmuir monolayers.

T. Vandamme, O. Shibata, M. Krafft, 2003, Journal of colloid and interface science.

DAT isn’t all that: cocaine reward and reinforcement requires Toll Like Receptor 4 signaling

S. Maier, L. Watkins, M. Baratta, 2014, Molecular Psychiatry.

Suppression of methamphetamine-seeking behavior by nicotinic agonists.

Tsuneyuki Yamamoto, K. Anggadiredja, T. Hiranita, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Opioid Activation of Toll-Like Receptor 4 Contributes to Drug Reinforcement

S. Maier, L. Watkins, S. Bland, 2012, The Journal of Neuroscience.

OpioidActivationofToll-LikeReceptor4Contributesto DrugReinforcement

S. Maier, S. Bland, R. R. Rozeske, 2012 .

Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain

R. Freyberg, J. Flores, D. Sulzer, 2016, Nature Communications.

Modafinil potentiates cocaine self-administration by a dopamine-independent mechanism: possible involvement of gap junctions

Z. Xi, A. Newman, C. Jordan, 2020, Neuropsychopharmacology.

Lack of Specific Involvement of (+)-Naloxone and (+)-Naltrexone on the Reinforcing and Neurochemical Effects of Cocaine and Opioids

G. Tanda, J. Katz, M. Mereu, 2016, Neuropsychopharmacology.

A Role for Sigma Receptors in Stimulant Self-Administration and Addiction.

W. Hong, C. McCurdy, J. Katz, 2017, Handbook of experimental pharmacology.

Preference for Distinct Functional Conformations of the Dopamine Transporter Alters the Relationship between Subjective Effects of Cocaine and Stimulation of Mesolimbic Dopamine

G. Tanda, J. Katz, M. Mereu, 2014, Biological Psychiatry.

Novel Approaches, Drug Candidates, and Targets in Pain Drug Discovery.

C. McCurdy, F. León, T. Hiranita, 2021, Journal of medicinal chemistry.

A role for sigma receptors in stimulant self-administration and addiction

T. Su, W. Hong, J. Katz, 2016, Behavioural pharmacology.

Differential Roles for Dopamine D1-Like and D2-Like Receptors in Mediating the Reinforcing Effects of Cocaine: Convergent Evidence from Pharmacological and Genetic Studies

G. Collins, T. Hiranita, 2015, Journal of alcoholism and drug dependence.

Medications Discovery: Importance of Assessment of Drug Self Administration Dose-Effect Curves

T. Hiranita, 2015, Journal of alcoholism and drug dependence.

The Reinforcing Effects of Nicotine in Humans and Nonhuman Primates: A Review of Intravenous Self-Administration Evidence and Future Directions for Research.

M. Paule, T. Hiranita, A. Goodwin, 2015, Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.

Stimulants as Specific Inducers of Dopamine-Independent σ Agonist Self-Administration in Rats

P. Soto, G. Tanda, T. Kopajtic, 2013, The Journal of Pharmacology and Experimental Therapeutics.

The effects of mitragynine and morphine on schedule-controlled responding and antinociception in rats

B. Avery, J. Wilkerson, C. McCurdy, 2019, Psychopharmacology.

Mice lacking the schizophrenia-associated protein FEZ1 manifest hyperactivity and enhanced responsiveness to psychostimulants.

K. Nakayama, J. Kira, T. Miyakawa, 2008, Human molecular genetics.

The use of hypercapnic conditions to assess opioid-induced respiratory depression in rats.

C. McCurdy, T. Hiranita, L. McMahon, 2021, Journal of pharmacological and toxicological methods.

Exploring the Chemistry of Alkaloids from Malaysian Mitragyna speciosa (Kratom) and the Role of Oxindoles on Human Opioid Receptors.

K. Abboud, S. Ramanathan, C. McCurdy, 2021, Journal of natural products.

Studies on diketopiperazine and dipeptide analogs as opioid receptor ligands.

V. Neugebauer, T. Abbruscato, C. McCurdy, 2023, European journal of medicinal chemistry.

Dopamine D2-Like Receptors and Behavioral Economics of Food Reinforcement

D. Grandy, S. Hursh, P. Soto, 2016, Neuropsychopharmacology.

2-Isoxazol-3-Phenyltropane Derivatives of Cocaine: Molecular and Atypical System Effects at the Dopamine Transporter

C. Lupica, A. Newman, P. Soto, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Assessment of Reinforcing Effects of Benztropine Analogs and Their Effects on Cocaine Self-Administration in Rats: Comparisons with Monoamine Uptake Inhibitors

A. Newman, P. Soto, J. Katz, 2009, Journal of Pharmacology and Experimental Therapeutics.

Assessment of Reinforcing Effects of Benztropine Analogues and Their Effects on Cocaine Self‐Administration: Comparisons with Monoamine Uptake Inhibitors

J. Katz, T. Hiranita, A. Newman, 2008 .

A tryptamine-derived catecholaminergic enhancer, (−)-1-(benzofuran-2-yl)-2-propylaminopentane [(−)-BPAP], attenuates reinstatement of methamphetamine-seeking behavior in rats

T. Yamamoto, T. Hiranita, Y. Nawata, 2010, Neuroscience.

A Cannabinoid CB1 Receptor Antagonist Ameliorates Impairment of Recognition Memory on Withdrawal from MDMA (Ecstasy)

Tsuneyuki Yamamoto, T. Hiranita, Y. Nawata, 2010, Neuropsychopharmacology.

Self-Administration of JWH-018 A Synthetic Cannabinoid in Experimentally Naïve Rats

T. Hiranita, 2015, Journal of alcoholism and drug dependence.

Self-Administration of an Endogenous Cannabinoid 2-Arachidonoylglycerol in Experimentally Naïve Rats

T. Hiranita, 2015, Journal of alcoholism and drug dependence.

Lack of cocaine-like discriminative-stimulus effects of &sgr;-receptor agonists in rats

P. Soto, G. Tanda, J. Katz, 2011, Behavioural pharmacology.

Investigation of the Adrenergic and Opioid Binding affinities, Metabolic Stability, Plasma Protein Binding Properties and Functional Effects of Selected Indole-based Kratom Alkaloids.

B. Avery, S. Ramanathan, C. McCurdy, 2019, Journal of medicinal chemistry.

The effects of mitragynine and morphine on schedule-controlled responding and antinociception in rats

B. Avery, J. Wilkerson, C. McCurdy, 2019, Psychopharmacology.

The Adrenergic a2 Receptor‐Mediated Discriminative‐Stimulus Effects of Mitragynine, the Primary Alkaloid in Kratom (Mitragyna Speciosa) in Rats

T. Hiranita, L. McMahon, M. Behnke, 2020, The FASEB Journal.

Potential Contribution of 7‐Hydroxymitragynine, a Metabolite of the Primary Kratom (Mitragyna Speciosa) Alkaloid Mitragynine, to the μ‐Opioid Activity of Mitragynine in Rats

T. Hiranita, Abhisheak Sharma, L. McMahon, 2020, The FASEB Journal.

In Vitro and In Vivo Pharmacological Comparison of Mu‐Opioid Receptor Activity of the Kratom (Mitragyna speciosa) Alkaloid Mitragynine and its Metabolite 7‐Hydroxymitragynine

C. McCurdy, T. Hiranita, L. McMahon, 2021, Alzheimer's & Dementia.

The Lack of Contribution of 7-Hydroxymitragynine to the Antinociceptive Effects of Mitragynine in Mice: A Pharmacokinetic and Pharmacodynamic Study

C. McCurdy, T. Hiranita, Abhisheak Sharma, 2021, Drug Metabolism and Disposition.

The discriminative stimulus effects of epibatidine in C57BL/6J mice

T. Hiranita, L. McMahon, Fernando B. de Moura, 2020, Behavioural pharmacology.

In vitro and in vivo pharmacology of kratom.

J. Wilkerson, C. McCurdy, T. Hiranita, 2022, Advances in pharmacology.

Citalopram enhances cocaine's subjective effects in rats

P. Soto, J. Katz, T. Hiranita, 2009, Behavioural pharmacology.

Involvement of the GABA/benzodiazepine receptor in the axiolytic-like effect of nociceptin/orphanin FQ.

Shigenori Watanabe, Taku Yamaguchi, R. Eyanagi, 2008, European journal of pharmacology.

Naltrexone attenuates cue- but not drug-induced methamphetamine seeking: a possible mechanism for the dissociation of primary and secondary reward

Tsuneyuki Yamamoto, K. Anggadiredja, T. Hiranita, 2004, Brain Research.

Preclinical Efficacy of Novel Vesicular Monoamine Transporter 2 Inhibitors as Antagonists of d-Methamphetamine Self-Administration in Rats

T. Hiranita, 2015, Journal of alcoholism and drug dependence.

Positron emission tomography (PET) imaging of nicotine-induced dopamine release in squirrel monkeys using [18F]Fallypride.

M. Paule, T. Hiranita, A. Goodwin, 2017, Drug and alcohol dependence.

Effects of benztropine analogs on delay discounting in rats

P. Soto, T. Hiranita, 2020, Psychopharmacology.

Role of amygdaloid nuclei in the anxiolytic-like effect of nociceptin/orphanin FQ in rats

Shigenori Watanabe, R. Eyanagi, T. Hiranita, 2008, Neuroscience Letters.

The stereotypy-inducing effects of N-substituted benztropine analogs alone and in combination with cocaine do not account for their blockade of cocaine self-administration

A. Newman, J. Katz, T. Hiranita, 2013, Psychopharmacology.

Choice for response alternatives differing in reinforcement frequency in dopamine D2 receptor mutant and Swiss-Webster mice

D. Grandy, P. Soto, J. Katz, 2014, Psychopharmacology.

Lack of Effects of Toll-Like Receptor 4 Antagonists on the Reinforcing Effects of Cocaine and Remifentanil

T. Hiranita, 2016, Journal of Alcoholism and Drug Dependence.

Correction to "Novel Approaches, Drug Candidates, and Targets in Pain Drug Discovery".

C. McCurdy, T. Hiranita, L. McMahon, 2021, Journal of medicinal chemistry.

Preference for Distinct Functional Conformations of the Dopamine Transporter Alters the Relationship between Subjective Effects of Cocaine and Stimulation of Mesolimbic Dopamine

G. Tanda, J. Katz, T. Hiranita, 2014, Biological Psychiatry.

Preclinical Efficacy of N-Substituted Benztropine Analogs as Antagonists of Methamphetamine Self-Administration in Rats

P. Soto, G. Tanda, T. Kopajtic, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Reinforcing Effects of σ-Receptor Agonists in Rats Trained to Self-Administer Cocaine

P. Soto, G. Tanda, J. Katz, 2010, Journal of Pharmacology and Experimental Therapeutics.

Decreases in Cocaine Self-Administration with Dual Inhibition of the Dopamine Transporter and (cid:1) Receptors

P. Soto, G. Tanda, T. Kopajtic, 2011 .

Decreases in Cocaine Self-Administration with Dual Inhibition of the Dopamine Transporter and (cid:1) Receptors

P. Soto, G. Tanda, T. Kopajtic, 2011 .

Dual DAT and sigma receptor inhibitors attenuate cocaine effects on nucleus accumbens dopamine dynamics in rats

G. Tanda, Jianjing Cao, T. Hiranita, 2024, The European journal of neuroscience.

The stereotypy-inducing effects of N-substituted benztropine analogs alone and in combination with cocaine do not account for their blockade of cocaine self-administration

A. Newman, J. Katz, T. Hiranita, 2012, Psychopharmacology.

In Vivo Significance of In Vitro Studies on G-Protein-Coupled Receptor Heteromers.

T. Hiranita, 2015, Journal of alcoholism and drug dependence.

Comparison of the µ-opioid receptor antagonists methocinnamox (MCAM) and naloxone to reverse and prevent the ventilatory depressant effects of fentanyl, carfentanil, 3-methylfentanyl, and heroin in male rats.

T. Hiranita, Nicholas P. Ho, C. P. France, 2024, The Journal of pharmacology and experimental therapeutics.

Ventilatory effects of fentanyl, heroin, and d -methamphetamine , alone and in mixtures, in male rats breathing normal air.

C. France, T. Hiranita, Nicholas P. Ho, 2023, The Journal of pharmacology and experimental therapeutics.

2-Isoxazol-3-Phenyltropane Derivatives of Cocaine: Molecular and Atypical System Effects at the Dopamine Transporter

C. Lupica, A. Newman, P. Soto, 2014, The Journal of Pharmacology and Experimental Therapeutics.

DAT Conformation Does Not Predict the Ability of Atypical Dopamine Uptake Inhibitors to Substitute for Cocaine.

T. Hiranita, 2016, Journal of alcoholism and drug dependence.

Nicotine Attenuates Relapse to Methamphetamine‐Seeking Behavior (Craving) in Rats

Shigenori Watanabe, Tsuneyuki Yamamoto, K. Anggadiredja, 2004, Annals of the New York Academy of Sciences.

Cannabis smoke and oral Δ9THC enhance working memory in aged but not young adult subjects

T. Hiranita, Erin C. Berthold, Alexandria S. Senetra, 2024, bioRxiv.