C. Cioffi

发表

Glycine transporter-1 inhibitors: a patent review (2011–2016)

C. Cioffi, 2018, Expert opinion on therapeutic patents.

Stringent Response Governs the Virulence and Oxidative Stress Resistance of Francisella tularensis

Zhuo Ma, C. Bakshi, C. Cioffi, 2019, bioRxiv.

Synthesis and Biological Evaluation of N-((1-(4-(Sulfonyl)piperazin-1-yl)cycloalkyl)methyl)benzamide Inhibitors of Glycine Transporter-1.

R. N. Davis, Shuang Liu, A. Mhyre, 2016, Journal of medicinal chemistry.

A non-retinoid antagonist of retinol-binding protein 4 rescues phenotype in a model of Stargardt disease without inhibiting the visual cycle

R. Allikmets, B. Rácz, P. Pearson, 2018, The Journal of Biological Chemistry.

Bicyclic [3.3.0]-Octahydrocyclopenta[c]pyrrolo Antagonists of Retinol Binding Protein 4: Potential Treatment of Atrophic Age-Related Macular Degeneration and Stargardt Disease.

Ping Chen, D. Kitchen, C. Cywin, 2015, Journal of medicinal chemistry.

Design, Synthesis, and Evaluation of Nonretinoid Retinol Binding Protein 4 Antagonists for the Potential Treatment of Atrophic Age-Related Macular Degeneration and Stargardt Disease

Ping Chen, D. Kitchen, C. Cywin, 2014, Journal of medicinal chemistry.

Discovery of Bispecific Antagonists of Retinol Binding Protein 4 That Stabilize Transthyretin Tetramers: Scaffolding Hopping, Optimization, and Preclinical Pharmacological Evaluation as a Potential Therapy for Two Common Age-Related Comorbidities.

B. Rácz, A. Váradi, K. Petrukhin, 2020, Journal of medicinal chemistry.

Convenient Palladium-Catalyzed Preparation of Primary Anilines Using a Fluorous Benzophenone Imine Reagent

R. J. Herr, C. Cioffi, Michael L. Berlin, 2004 .

8-Aminocyclazocine analogues: synthesis and structure-activity relationships.

J. Bidlack, M. Wentland, W. Duan, 2000, Bioorganic & medicinal chemistry letters.

Design, Synthesis, and Preclinical Efficacy of Novel Nonretinoid Antagonists of Retinol-Binding Protein 4 in the Mouse Model of Hepatic Steatosis.

Ping Chen, D. Kitchen, W. Blaner, 2019, Journal of medicinal chemistry.

Inhibitors of Glycine Transporter-1: Potential Therapeutics for the Treatment of CNS Disorders.

C. Cioffi, P. Guzzo, 2016, Current topics in medicinal chemistry.

G. Montelione, R. Krug, Khushboo Bafna, 2022, Frontiers in Chemistry.

Design, synthesis, and SAR of N-((1-(4-(propylsulfonyl)piperazin-1-yl)cycloalkyl)methyl)benzamide inhibitors of glycine transporter-1.

Shuang Liu, A. Mhyre, J. Maeng, 2013, Bioorganic & medicinal chemistry letters.

Recent Developments in Glycine Transporter-1 Inhibitors

Shuang Liu, C. Cioffi, M. Wolf, 2010 .

Generation of 3-pyridyl biaryl systems via palladium-catalyzed Suzuki cross-couplings of aryl halides with 3-pyridylboroxin.

R. J. Herr, C. Cioffi, Justin J. Richards, 2004, The Journal of organic chemistry.

Synthesis of 2-aminobenzoxazoles using tetramethyl orthocarbonate or 1,1-dichlorodiphenoxymethane.

C. Cioffi, John J. Lansing, H. Yüksel, 2010, The Journal of organic chemistry.

Generation of 3-pyridyl biaryl systems via palladium-catalyzed Suzuki cross-couplings of aryl halides with 3-pyridylboroxin.

R. J. Herr, C. Cioffi, Justin J. Richards, 2004, The Journal of organic chemistry.

Synthesis of 24.xi.-Squalamine, an Anti-Infective Steroidal Polyamine

L. Frye, W. Kinney, A. D. Pechulis, 1995 .

Introduction: Overview of the Human Eye, Mammalian Retina, and the Retinoid Visual Cycle

Christopher L. Cioffi, C. Cioffi, 2020 .

Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases

C. Cioffi, Bakall M. Choudhary, Malek K. Mears, 2020 .

Inhibition of Glycine Re-Uptake: A Potential Approach for Treating Pain by Augmenting Glycine-Mediated Spinal Neurotransmission and Blunting Central Nociceptive Signaling

C. Cioffi, 2021, Biomolecules.

Photoswitchable ORG25543 Congener Enables Optical Control of Glycine Transporter 2

R. Vandenberg, T. Rawling, Shannon N. Mostyn, 2020, ACS chemical neuroscience.

Modulation of Glycine-Mediated Spinal Neurotransmission for the Treatment of Chronic Pain.

C. Cioffi, 2017, Journal of medicinal chemistry.

A novel RPE65 inhibitor CU239 suppresses visual cycle and prevents retinal degeneration.

Jian-xing Ma, K. Petrukhin, G. Moiseyev, 2018, Biochimica et biophysica acta. Molecular basis of disease.

Modulation of NMDA receptor function as a treatment for schizophrenia.

C. Cioffi, 2013, Bioorganic & medicinal chemistry letters.

Stringent response governs the oxidative stress resistance and virulence of Francisella tularensis

Zhuo Ma, C. Bakshi, C. Cioffi, 2019, PloS one.

Syntheses and opioid receptor binding affinities of 8-amino-2,6-methano-3-benzazocines.

Xufeng Sun, J. Bidlack, M. Wentland, 2003, Journal of medicinal chemistry.

Convenient Palladium‐Catalyzed Preparation of Primary Anilines Using a Fluorous Benzophenone Imine Reagent.

R. J. Herr, C. Cioffi, Michael L. Berlin, 2004 .

The novel visual cycle inhibitor (±)-RPE65-61 protects retinal photoreceptors from light-induced degeneration

Jian-xing Ma, Yuhong Wang, K. Petrukhin, 2022, PloS one.

Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome.

David D. Manning, N. Barnes, C. Brady, 2011, Bioorganic & medicinal chemistry letters.

Discovery of 2-substituted benzoxazole carboxamides as 5-HT3 receptor antagonists.

David D. Manning, Jianqing Chen, Marlene L. Cohen, 2010, Bioorganic & medicinal chemistry letters.

A novel RPE65 inhibitor CU239 suppresses visual cycle and prevents retinal degeneration.

Jian-xing Ma, K. Petrukhin, G. Moiseyev, 2018, Biochimica et biophysica acta. Molecular basis of disease.