C. Pessoa-Mahana

发表

Synthesis, docking and pharmacological evaluation of novel homo- and hetero-bis 3-piperazinylpropylindole derivatives at SERT and 5-HT1A receptor.

R. Araya-Maturana, A. Fierro, P. Iturriaga-Vásquez, 2013, Bioorganic & medicinal chemistry.

2D-QSAR and 3D-QSAR/CoMSIA Studies on a Series of (R)-2-((2-(1H-Indol-2-yl)ethyl)amino)-1-Phenylethan-1-ol with Human β3-Adrenergic Activity

G. Apablaza, C. Morales-Verdejo, Jorge Soto-Delgado, 2017, Molecules.

Synthesis and Docking of Novel 3‐Indolylpropyl Derivatives as New Polypharmacological Agents Displaying Affinity for 5‐HT1AR/SERT

R. Araya-Maturana, P. Iturriaga-Vásquez, M. Reyes-Parada, 2017, Archiv der Pharmazie.

Nitrofuran drugs beyond redox cycling: Evidence of nitroreduction-independent cytotoxicity mechanism.

R. Araya-Maturana, H. Pessoa‐Mahana, C. Pessoa-Mahana, 2020, Toxicology and applied pharmacology.

Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor.

V. Di Marzo, M. Torres, P. Iturriaga-Vásquez, 2016, European journal of medicinal chemistry.

Synthesis and Biological Screening of Novel Indolalkyl Arenes Targeting the Serotonine Transporter

Gonzalo Recabarren‐Gajardo, P. Iturriaga-Vásquez, H. Pessoa‐Mahana, 2014, Archiv der Pharmazie.

Interaction of 5-aminosalicylic acid with nitrous acid: Formation of the diazonium derivative and nitric oxide release

P. Hoffmann, E. Lissi, G. Ferrer-Sueta, 2011 .

Synthesis, 5-hydroxytryptamine1A receptor affinity and docking studies of 3-[3-(4-aryl-1-piperazinyl)-propyl]-1H-indole derivatives.

R. Araya-Maturana, P. Iturriaga-Vásquez, M. Reyes-Parada, 2012, Chemical & pharmaceutical bulletin.

Synthesis of 2‐Benzothienyl Carbonyl 4‐Arylpiperazines as Novel Delavirdine Analogs

R. Araya-Maturana, H. Pessoa‐Mahana, C. Pessoa-Mahana, 2007 .

1-BENZOYL-2-(2-NITROPHENYL)-1H-BENZIMIDAZOLE DERIVATIVES: A NOVEL APPROACH TO THE DEVELOPMENT OF NEW HIV-1 REVERSE TRANSCRIPTASE INHIBITORS

Tomas Perez-Acle, Carlos F. Lagos, T. Pérez-Acle, 2007 .

A Facile Approach for New Dibenzo [b,f][1,5] Diazocinones

R. Araya-Maturana, H. Pessoa‐Mahana, C. Pessoa-Mahana, 2005 .

Biological evaluation of novel 6-Arylbenzimidazo[1,2-c]quinazoline derivatives as inhibitors of LPS-induced TNF-alpha secretion.

A. Edwards, H. Pessoa‐Mahana, C. Pessoa-Mahana, 2008, Biological research.

A Facile Approach for New Dibenzo[b,f][1,5]-diazocinones.

R. Araya-Maturana, H. Pessoa‐Mahana, C. Pessoa-Mahana, 2005 .

Solvent-Free Synthesis of 6-Arylbenzimidazo[1,2-c]quinazolines under Microwave Irradiation.

R. Salazar, R. Araya-Maturana, H. Pessoa‐Mahana, 2004 .

Solvent-Free Synthesis of 6-Arylbenzimidazo[1,2-c]quinazolines under Microwave Irradiation

R. Salazar, R. Araya-Maturana, H. Pessoa‐Mahana, 2004 .

Reaction of spiroanthracenones with DDQ: a one-pot synthesis of benz[a]anthraquinones

R. Tapia, J. Valderrama, C. Pessoa-Mahana, 1994 .

STUDIES ON QUINONES. PART 36.1 SYNTHESIS AND TRYPANOCIDAL ACTIVITY OF 2-ALKOXYCARBONYLBENZO[b]THIOPHENE-4,7-QUINONES

A. Rojas de Arias, H. Pessoa‐Mahana, J. Valderrama, 2002 .

Synthesis, characterization, and electrochemical studies of new 5‐ and 6‐nitro N‐acyl‐1H‐indazoles

M. D. Valle, M. Gacitúa, Gonzalo Recabarren‐Gajardo, 2011 .

Evaluation of the Membrane Permeability (PAMPA and Skin) of Benzimidazoles with Potential Cannabinoid Activity and their Relation with the Biopharmaceutics Classification System (BCS)

J. Mella-Raipán, C. Pessoa-Mahana, M. J. Álvarez-Figueroa, 2011, AAPS PharmSciTech.

Synthesis, Docking, 3-D-Qsar, and Biological Assays of Novel Indole Derivatives Targeting Serotonin Transporter, Dopamine D2 Receptor, and Mao-A Enzyme: In the Pursuit for Potential Multitarget Directed Ligands

R. Araya-Maturana, P. Iturriaga-Vásquez, M. Reyes-Parada, 2020, Molecules.

Synthesis of 4‐Arylpiperazine Derivatives of Moclobemide: Potential Antidepressants with a Dual Mode of Action

R. Araya-Maturana, H. Pessoa‐Mahana, C. Pessoa-Mahana, 2004 .

Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer's disease.

P. Jaque, R. Araya-Maturana, Marcos Lorca, 2020, European journal of medicinal chemistry.

Cannabidiol binding and negative allosteric modulation at the cannabinoid type 1 receptor in the presence of delta-9-tetrahydrocannabinol: An In Silico study

A. Fierro, C. Pessoa-Mahana, Hery Chung, 2019, PloS one.

Design, Synthesis, Binding and Docking-Based 3D-QSAR Studies of 2-Pyridylbenzimidazoles—A New Family of High Affinity CB1 Cannabinoid Ligands

Gonzalo Recabarren‐Gajardo, C. Lagos, P. Iturriaga-Vásquez, 2013, Molecules.

Synthesis and biological evaluation of potential acetylcholinesterase inhibitors based on a benzoxazine core

M. Kogan, R. Araya-Maturana, P. Iturriaga-Vásquez, 2018, Archiv der Pharmazie.

Synthesis, Docking Studies and Biological Evaluation of Benzo[b]thiophen-2-yl-3-(4-arylpiperazin-1-yl)-propan-1-one Derivatives on 5-HT1A Serotonin Receptors

R. Araya-Maturana, Gonzalo Recabarren‐Gajardo, H. Pessoa‐Mahana, 2012, Molecules.

Computational modeling study of functional microdomains in cannabinoid receptor type 1.

Tomas Perez-Acle, T. Pérez-Acle, J. Garate, 2008, Bioorganic & medicinal chemistry.

Antioxidant Capacity of Pure Compounds and Complex Mixtures Evaluated by the ORAC-Pyrogallol Red Assay in the Presence of Triton X-100 Micelles

E. Lissi, J. Mella-Raipán, C. López-Alarcón, 2010, Molecules.

Three-Dimensional Quantitative Structure-Activity Relationships (3D-QSAR) on a Series of Piperazine-Carboxamides Fatty Acid Amide Hydrolase (FAAH) Inhibitors as a Useful Tool for the Design of New Cannabinoid Ligands

Marcos Lorca, J. Mella, C. Pessoa-Mahana, 2019, International journal of molecular sciences.

SYNTHESIS OF CONFORMATIONALLY RESTRICTED N-{4-[4-(4,7-DIMETHOXY-BENZO[b]THIOPHENE-2-CARBONYL)-1-PIPERAZINYL]-PHENYL}-ARYLCARBOXAMIDES POTENTIAL LIGANDS WITH 5-HT1A BINDING AFFINITY

R. Araya-Maturana, H. Pessoa‐Mahana, C. Pessoa-Mahana, 2009 .

THIOPHENE – 2 – CARBONYL )-1-PIPERAZINYL ] – PHENYL }-ARYLCARBOXAMIDES POTENTIAL LIGANDS WITH 5-HT 1 A BINDING AFFINITY

R. Araya-Maturana, H. Pessoa‐Mahana, C. Saitz, 2009 .

Synthesis of Benzo[b]thiophene Carboxamides Connected to 4‐Arylpiperazines through a Benzylic Spacer: Potential Ligands with 5‐HT1A Binding Affinity

R. Araya-Maturana, H. Pessoa‐Mahana, C. Saitz, 2007 .

Extended N-Arylsulfonylindoles as 5-HT6 Receptor Antagonists: Design, Synthesis & Biological Evaluation

Gonzalo Recabarren‐Gajardo, C. Lagos, J. Mella-Raipán, 2016, Molecules.

Design, Synthesis, Biological Evaluation and Binding Mode Modeling of Benzimidazole Derivatives Targeting the Cannabinoid Receptor Type 1

Gonzalo Recabarren‐Gajardo, C. Lagos, A. M. Zárate, 2015, Archiv der Pharmazie.

3D-QSAR on a Series of Pyrimidinyl-Piperazine-Carboxamides Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors as a Useful Tool to Obtain Novel Endocannabinoid Enhancers

Marcos Lorca, J. Mella, C. Pessoa-Mahana, 2018 .