L. Azam

发表

Positional Scanning Mutagenesis of α-Conotoxin PeIA Identifies Critical Residues That Confer Potency and Selectivity for α6/α3β2β3 and α3β2 Nicotinic Acetylcholine Receptors*

J. McIntosh, Sean B. Christensen, A. Hone, 2013, The Journal of Biological Chemistry.

Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors

J. McIntosh, L. Azam, 2009, Acta Pharmacologica Sinica.

Molecular Interaction of a-Conotoxin RgIA with the Rat a 9 a 10 Nicotinic Acetylcholine Receptor s

J. McIntosh, S. Tzartos, A. Papakyriakou, 2016 .

Molecular Interaction of α-Conotoxin RgIA with the Rat α9α10 Nicotinic Acetylcholine Receptor

J. McIntosh, S. Tzartos, A. Papakyriakou, 2015, Molecular Pharmacology.

Co‐expression of NaVβ subunits alters the kinetics of inhibition of voltage‐gated sodium channels by pore‐blocking μ‐conotoxins

D. Yoshikami, J. Rivier, G. Bulaj, 2013, British journal of pharmacology.

α-Conotoxin BuIA, a Novel Peptide from Conus bullatus, Distinguishes among Neuronal Nicotinic Acetylcholine Receptors*

J. McIntosh, J. Stitzel, B. Olivera, 2005, Journal of Biological Chemistry.

Alpha-conotoxin BuIA, a novel peptide from Conus bullatus, distinguishes among neuronal nicotinic acetylcholine receptors.

J. McIntosh, J. Stitzel, B. Olivera, 2005, The Journal of biological chemistry.

Structure/Function Characterization of μ-Conotoxin KIIIA, an Analgesic, Nearly Irreversible Blocker of Mammalian Neuronal Sodium Channels*

Brian J. Smith, D. Yoshikami, R. Norton, 2007, Journal of Biological Chemistry.

Structure, dynamics and selectivity of the sodium channel blocker µ-conotoxin SIIIA†,,‡

D. Yoshikami, R. Norton, S. Yao, 2014 .

Systemin the Amphibian Sympathetic Nervous -Conotoxins PVIA and SVIE on Sodium δ Effects of

B. Ueberheide, J. Rivier, J. Biggs, 2015 .

A disulfide tether stabilizes the block of sodium channels by the conotoxin μO§-GVIIJ

B. Ueberheide, D. Yoshikami, H. M. Zhou, 2014, Proceedings of the National Academy of Sciences.

α-Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between α6ß4 and α6ß2 nicotinic acetylcholine receptors and blocks nicotine-stimulated norepinephrine release.

J. Changeux, U. Maskos, J. McIntosh, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Na(V)1.2, 1.6 and 1.7.

D. Yoshikami, R. Norton, G. Bulaj, 2008, Biochemical pharmacology.

α-Conotoxins Identify the α3β4* Subtype as the Predominant Nicotinic Acetylcholine Receptor Expressed in Human Adrenal Chromaffin Cells

J. Lindstrom, J. McIntosh, P. Whiteaker, 2015, Molecular Pharmacology.

Developmental regulation of nicotinic acetylcholine receptors within midbrain dopamine neurons

F. Leslie, L. Azam, Y. Chen, 2007, Neuroscience.

Α- and β-subunit composition of voltage-gated sodium channels investigated with μ-conotoxins and the recently discovered μO§-conotoxin GVIIJ.

D. Yoshikami, J. Rivier, B. Olivera, 2015, Journal of neurophysiology.

Unexpected synergism between Tetrodotoxin and μ-conotoxin in blocking voltage-gated sodium channels

M. Zhang, D. Yoshikami, R. French, 2009 .

STRUCTURE/FUNCTION CHARACTERIZATION OF μ -CONOTOXIN KIIIA, AN ANALGESIC, NEARLY IRREVERSIBLE BLOCKER OF NEURONAL MAMMALIAN SODIUM CHANNELS*

D. Yoshikami, R. Norton, J. Rivier, 2007 .

Analogs of alpha-conotoxin MII are selective for alpha6-containing nicotinic acetylcholine receptors.

J. Lindstrom, M. Marks, A. Kuryatov, 2004, Molecular pharmacology.

Structure, dynamics, and selectivity of the sodium channel blocker mu-conotoxin SIIIA.

D. Yoshikami, R. Norton, S. Yao, 2008, Biochemistry.

Probing the Redox States of Sodium Channel Cysteines at the Binding Site of μO§-Conotoxin GVIIJ.

D. Yoshikami, G. Bulaj, B. Olivera, 2015, Biochemistry.

μ-Conotoxins that differentially block sodium channels NaV1.1 through 1.8 identify those responsible for action potentials in sciatic nerve

D. Yoshikami, G. Bulaj, B. Olivera, 2011, Proceedings of the National Academy of Sciences.

Pruning nature: Biodiversity-derived discovery of novel sodium channel blocking conotoxins from Conus bullatus.

D. Yoshikami, G. Bulaj, B. Olivera, 2009, Toxicon : official journal of the International Society on Toxinology.

Analogs of α-conotoxin MII are selective for α6-containing nicotinic acetylcholine receptors

Michael J. Marks, James E. Garrett, J. Lindstrom, 2004 .

Molecular basis for the differential sensitivity of rat and human α9α10 nAChRs to α‐conotoxin RgIA

L. Azam, J. McIntosh, 2012, Journal of neurochemistry.

Characterization of Nicotinic Acetylcholine Receptors That Modulate Nicotine-Evoked [3H]Norepinephrine Release from Mouse Hippocampal Synaptosomes

J. McIntosh, L. Azam, 2006, Molecular Pharmacology.

Effect of Novel α-Conotoxins on Nicotine-Stimulated [3H]Dopamine Release from Rat Striatal Synaptosomes

J. McIntosh, L. Azam, 2005, Journal of Pharmacology and Experimental Therapeutics.

NaVβ Subunits Modulate the Inhibition of NaV1.8 by the Analgesic Gating Modifier μO-Conotoxin MrVIB

D. Yoshikami, G. Bulaj, B. Olivera, 2011, Journal of Pharmacology and Experimental Therapeutics.

Expression of neuronal nicotinic acetylcholine receptor subunit mRNAs within midbrain dopamine neurons

F. Leslie, L. Azam, U. Winzer-Serhan, 2002, The Journal of comparative neurology.

αM-Conotoxin MIIIJ Blocks Nicotinic Acetylcholine Receptors at Neuromuscular Junctions of Frog and Fish

D. Yoshikami, J. McIntosh, B. Olivera, 2020, Toxins.

Co-expression of α7 and β2 nicotinic acetylcholine receptor subunit mRNAs within rat brain cholinergic neurons

F. Leslie, L. Azam, U. Winzer-Serhan, 2003, Neuroscience.

Co-expression of alpha7 and beta2 nicotinic acetylcholine receptor subunit mRNAs within rat brain cholinergic neurons.