Xavier Garcia-Ortega

发表

Innovative Bioprocess Strategies Combining Physiological Control and Strain Engineering of Pichia pastoris to Improve Recombinant Protein Production

José Luis Montesinos-Seguí, F. Valero, Arnau Gasset, 2022, Frontiers in Bioengineering and Biotechnology.

Physiological state as transferable operating criterion to improve recombinant protein production in Pichia pastoris through oxygen limitation

José Luis Montesinos-Seguí, F. Valero, Xavier Garcia-Ortega, 2017 .

Fed-batch operational strategies for recombinant Fab production with Pichia pastoris using the constitutive GAP promoter

Francisco Valero, Pau Ferrer, José Luis Montesinos, 2013 .

Specific growth rate governs AOX1 gene expression, affecting the production kinetics of Pichia pastoris (Komagataella phaffii) PAOX1-driven recombinant producer strains with different target gene dosage

José Luis Montesinos-Seguí, Miguel Angel Nieto-Taype, F. Valero, 2019, Microbial Cell Factories.

Rationale‐based selection of optimal operating strategies and gene dosage impact on recombinant protein production in Komagataella phaffii (Pichia pastoris)

José Luis Montesinos-Seguí, Miguel Angel Nieto-Taype, F. Valero, 2019, Microbial biotechnology.

Bioprocess performance analysis of novel methanol-independent promoters for recombinant protein production with Pichia pastoris

José Luis Montesinos-Seguí, Miguel Angel Nieto-Taype, M. Penttilä, 2021, Microbial Cell Factories.

Scalable production and application of Pichia pastoris whole cell catalysts expressing human cytochrome P450 2C9

José Luis Montesinos-Seguí, A. Glieder, F. Valero, 2021, Microbial Cell Factories.

Continuous Cultivation as a Tool Toward the Rational Bioprocess Development With Pichia Pastoris Cell Factory

Francisco Valero, Joan Albiol, José Luis Montesinos-Seguí, 2020, Frontiers in Bioengineering and Biotechnology.

Rational development of bioprocess engineering strategies for recombinant protein production in Pichia pastoris (Komagataella phaffi) using the methanol free GAP promoter. Where do we stand?

Francisco Valero, Pau Ferrer, Joan Albiol, 2019, New biotechnology.

Continuous operation, a realistic alternative to fed-batch fermentation for the production of recombinant lipase B from Candida antarctica under the constitutive promoter PGK in Pichia pastoris

José Luis Montesinos-Seguí, F. Valero, Xavier Garcia-Ortega, 2019, Biochemical Engineering Journal.

A step forward to improve recombinant protein production in Pichia pastoris : from specific growth rate effect on protein secretion to carbon-starving conditions as advanced strategy.

P. Ferrer, F. Valero, J. Montesinos, 2016 .

Overall Key Performance Indicator to Optimizing Operation of High-Pressure Homogenizers for a Reliable Quantification of Intracellular Components in Pichia pastoris

Cecilia Reyes, José Luis Montesinos, Xavier Garcia-Ortega, 2015, Front. Bioeng. Biotechnol..

The effect of hypoxia on the lipidome of recombinant Pichia pastoris

I. Feussner, G. Daum, P. Ferrer, 2017, Microbial Cell Factories.

Enabling growth-decoupled Komagataella phaffii recombinant protein production based on the methanol-free PDH promoter

Miguel Angel Nieto-Taype, J. E. Fischer, A. Glieder, 2023, Frontiers in Bioengineering and Biotechnology.

Scalable protein production by Komagataella phaffii enabled by ARS plasmids and carbon source-based selection

Xavier Garcia-Ortega, Florian Weiss, Guillermo Requena-Moreno, 2024, Microbial cell factories.