A. Mogg

发表

Epibatidine isomers and analogues: structure-activity relationships.

L. Broad, J. Malpass, Richard White, 2006, Bioorganic & medicinal chemistry letters.

Methyllycaconitine is a potent antagonist of alpha-conotoxin-MII-sensitive presynaptic nicotinic acetylcholine receptors in rat striatum.

A. C. Collins, A. Collins, M. Marks, 2002, The Journal of pharmacology and experimental therapeutics.

Ligands selective for α4β2 but not α3β4 or α7 nicotinic receptors generalise to the nicotine discriminative stimulus in the rat

P. Szekeres, Janice W. Smith, M. Tricklebank, 2006, Psychopharmacology.

Identification and pharmacological profile of SPP1, a potent, functionally selective and brain penetrant agonist at muscarinic M1 receptors

David A. Evans, E. Sher, V. Barth, 2018, British journal of pharmacology.

PAPER Pharmacological proﬁling of the TRPV3 channel in recombinant and native assays

C. Ruble, L. Broad, D. Ursu, 2014 .

Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs

P. Sexton, A. Christopoulos, S. Sakata, 2020, Nature Chemical Biology.

Presynaptic nicotinic acetylcholine receptors: subtypes mediating neurotransmitter release

I. Jones, S. Wonnacott, Bradly Alicea, 2001 .

Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes

C. Langmead, P. Sexton, A. Christopoulos, 2018, Molecular Pharmacology.

Functional responses and subunit composition of presynaptic nicotinic receptor subtypes explored using the novel agonist 5-iodo-A-85380

S. Wonnacott, A. Mogg, I. Pullar, 2004, Neuropharmacology.

Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain.

S. Bevan, M. Perretti, Ki-Wook Kim, 2014, The Journal of clinical investigation.

Sazetidine-A Is a Potent and Selective Agonist at Native and Recombinant α4β2 Nicotinic Acetylcholine Receptors

E. Sher, B. Heinz, L. Broad, 2008, Molecular Pharmacology.

Intracellular Ca2+ signals evoked by stimulation of nicotinic acetylcholine receptors in SH‐SY5Y cells: contribution of voltage‐operated Ca2+ channels and Ca2+ stores

S. Wonnacott, F. Dajas-Bailador, A. Mogg, 2002, Journal of neurochemistry.

Recombinant α4β2 Nicotinic Acetylcholine Receptors

E. Sher, B. Heinz, L. Broad, 2008 .

Paradoxical effects of the cannabinoid CB2 receptor agonist GW405833 on rat osteoarthritic knee joint pain.

E. Nisenbaum, J. McDougall, L. Broad, 2010, Osteoarthritis and cartilage.

Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons

J. Isaac, E. Sher, J. Dage, 2014, Psychopharmacology.

CARDIAC ARRHYTHMIA: EFFECT OF VAGAL STIMULATION AND HYPOXIA

A. Mogg, W. Hamelberg, J. Jacoby, 1955, Anesthesiology.

PET ligands [18F]LSN3316612 and [11C]LSN3316612 quantify O-linked-β-N-acetyl-glucosamine hydrolase in the brain

S. Zoghbi, J. Liow, R. Gladding, 2020, Science Translational Medicine.

M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss

J. Wess, P. Sexton, A. Christopoulos, 2016, The Journal of clinical investigation.

Activation of transient receptor potential ankyrin 1 induces CGRP release from spinal cord synaptosomes

S. Bevan, L. Broad, C. Gentry, 2015, Pharmacology research & perspectives.

Molecular Mechanisms of Action and In Vivo Validation of an M4 Muscarinic Acetylcholine Receptor Allosteric Modulator with Potential Antipsychotic Properties

P. Sexton, A. Christopoulos, D. McKinzie, 2010, Neuropsychopharmacology.

Gain and loss of function of P2X7 receptors: mechanisms, pharmacology and relevance to diabetic neuropathic pain

L. Munsie, Y. Qian, E. Sher, 2014, Molecular pain.

TRPV3 in Drug Development

Dominic L. Li, L. Broad, K. Knopp, 2016, Pharmaceuticals.

Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the Hippocampus

Christian C. Felder, Jack R. Mellor, J. Isaac, 2015, Cerebral cortex.

123I-Iododexetimide Preferentially Binds to the Muscarinic Receptor Subtype M1 In Vivo

Geor Bakker, David A. Collier, Vanessa N. Barth, 2015, The Journal of Nuclear Medicine.

TRP channels as emerging targets for pain therapeutics

M. Blanco, D. Bleakman, L. Broad, 2009, Expert opinion on therapeutic targets.

In Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission Tomography

V. Barth, C. Felder, T. Eessalu, 2018, The Journal of Pharmacology and Experimental Therapeutics.

An Antibody Biosensor Establishes the Activation of the M1 Muscarinic Acetylcholine Receptor during Learning and Memory*♦

A. Tobin, A. Bottrill, C. Felder, 2016, The Journal of Biological Chemistry.

Current status of muscarinic M1 and M4 receptors as drug targets for neurodegenerative diseases

David A. Evans, C. Felder, L. Broad, 2018, Neuropharmacology.

Ligands selective for alpha4beta2 but not alpha3beta4 or alpha7 nicotinic receptors generalise to the nicotine discriminative stimulus in the rat.

P. Szekeres, Janice W. Smith, M. Tricklebank, 2007, Psychopharmacology.

Presynaptic nicotinic receptors modulating dopamine release in the rat striatum.

I. Jones, S. Wonnacott, A. Mogg, 2000, European journal of pharmacology.

Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons

J. Isaac, E. Sher, J. Dage, 2014, Psychopharmacology.

The subtype-selective nicotinic acetylcholine receptor positive allosteric potentiator 2087101 differentially facilitates neurotransmission in the brain.

E. Sher, G. de Filippi, K. Phillips, 2010, European journal of pharmacology.

Presynaptic nicotinic acetylcholine receptors: subtypes mediating neurotransmitter release

I. Jones, S. Wonnacott, Bradly Alicea, 2001 .

Pharmacological profiling of the TRPV3 channel in recombinant and native assays

C. Ruble, L. Broad, D. Ursu, 2014, British journal of pharmacology.

M 1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss

P. Sexton, A. Christopoulos, J. Steinert, 2022 .

M 1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss

P. Sexton, A. Christopoulos, J. Steinert, 2022 .